This document provides information on dosage guidelines and administration instructions for several vasoactive medications including adrenaline, noradrenaline, dobutamine, dopamine, nitroglycerine, nitroprusside, heparin, fentanyl, and midazolam. It includes details on drug compatibility, dilution, concentration, dosage ranges, stability times, and infusion rate tables based on patient weight. Proper light protection during preparation and a maximum 24 hour infusion time are noted for several of the drugs.
Pharmacology is an important part of ACLS program. In ACLS Program,we are using many essential drugs for surviving cardiac arrest cases in Emergency department. We are introducing ACLS which is locally called ARC ( Advanced Resuscitation Course) started in Square Hospitals Ltd,Dhaka,Bangladesh. Hope it will help many health care provider to know the useful medication in case of CPR.
Pharmacology is an important part of ACLS program. In ACLS Program,we are using many essential drugs for surviving cardiac arrest cases in Emergency department. We are introducing ACLS which is locally called ARC ( Advanced Resuscitation Course) started in Square Hospitals Ltd,Dhaka,Bangladesh. Hope it will help many health care provider to know the useful medication in case of CPR.
Comprehensive presentation on intra arterial blood pressure with a good insight into the the basic physics and brief look into the risks and complications.
The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle (myocardial contractility). However, it can also refer to pathological conditions. For example, enlarged heart muscle (ventricular hypertrophy) can increase inotropic state, whereas dead heart muscle (myocardial infarction) can decrease it.
by the renowned pediatrician, Dr Satish Deopujari,
National Chairperson (Ex)
Intensive Care Chapter I A P
Founder Chairman.....
National conference on pediatric critical care
Professor of pediatrics ( Hon ) JNMC:Wardha
Nagpur : INDIA
Pediatric Emergency & Medications Doses By Dr Essam SidqiEssam Sidqi Yaqoob
Pediatrics medications doses and its emergency related cases were always problematic..
I hope with this presentation, it be much simpler and much more beneficial and easier to be accessed quickly in emergencies.
Comprehensive presentation on intra arterial blood pressure with a good insight into the the basic physics and brief look into the risks and complications.
The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle (myocardial contractility). However, it can also refer to pathological conditions. For example, enlarged heart muscle (ventricular hypertrophy) can increase inotropic state, whereas dead heart muscle (myocardial infarction) can decrease it.
by the renowned pediatrician, Dr Satish Deopujari,
National Chairperson (Ex)
Intensive Care Chapter I A P
Founder Chairman.....
National conference on pediatric critical care
Professor of pediatrics ( Hon ) JNMC:Wardha
Nagpur : INDIA
Pediatric Emergency & Medications Doses By Dr Essam SidqiEssam Sidqi Yaqoob
Pediatrics medications doses and its emergency related cases were always problematic..
I hope with this presentation, it be much simpler and much more beneficial and easier to be accessed quickly in emergencies.
Formulation and evaluation of sitagliptan floating tabletsSriramNagarajan19
Gastro retentive dosage form using Guar gum was prepared to develop floating tablets of Sitagliptin that could retain in the stomach for longer periods of time delivering the drug to the site of action, i.e., stomach. The pre-compression parameters of all formulations showed good flow properties and these can be used for tablet manufacture. The post-compression parameters of all formulations were determined and the values were found to be satisfactory. From the drug content and in-vitro dissolution studies of the formulations, it was concluded that the formulation F9 i.e. the formulation containing guargum, Sodium bicarbonate, citric acid, micro crystalline cellulose and Magnesium stearate is the best formulation. As a result of this study it may be concluded that the floating tablets using a guar gum in optimized concentration can be used to increase the GRT of the dissolution fluid in the stomach to deliver the drug in a sustained manner. The concept of formulating floating tablets of Sitagliptin offers a suitable and practical approach in serving desired objectives of gastro retentive floating tablets.
3rd Edition Pediatrics Emergency And Medications Doses By Dr Essam Sidqi.pdfEssam Sidqi Yaqoob
3rd Edition and Most Updated Version.
Pediatrics medications doses and its emergency related cases were always problematic for new junior doctors.
I hope with this new update, I tried to make it much simpler and much easier to be accessed quickly in emergencies to reach its maximum benefits.
Any comment or recommendation is welcomed.
Thank you.
Dr. Essam Sidqi
August 2023
Edits:
Dopamine Amp.
200mg/5ml, 400mg/10ml
1-5mcg/kg/min.
Then 5-20mcg/kg/min.
(Max. 50mcg/kg/min.)
5cc + 45 D5%
0.015-0.08cc/kg/hr.
Then 0.08-0.3cc/kg/hr.
(Max.0.75cc/kg/hr.)
Comprehensive Investigation of the Utilization of SFC/ESI Positive Mode MS fo...Waters Corporation
Bioanalysis and drug metabolism studies are critical parts of the drug development process. The aim of these studies is to identify and quantify drugs and their associated metabolites in biofluids such as plasma and urine. Typically reversed-phase chromatography coupled with mass spectrometry is often the analytical technique of choice utilized in the analyses due to the specificity and sensitivity of the technique. However, due to the complexity of the biofluid samples accurate and precise measurements can become challenging due to poor chromatographic peak shape, insufficient chromatographic resolution from matrix components and incompatible sample compositions.
Recent advancements in the field of super critical fluid chromatography (SFC) have lead to the development of sub 2 micron chromatographic separations coupled mass spectrometry operating under positive ESI mode. In the work presented here the applicability of SFC for both chiral and achiral bioanalysis is shown. The orthogonal separation selectivity compared with reversed-phase separations and tolerance for high organic sample compositions will be discussed. This work further presents a critical evaluation of the influence of mobile phase and make up flow modifiers on the sensitivity and selectivity of probe pharmaceuticals analyzed under SFC/ESI positive mode MS conditions.
Paul Rainville of Waters Corporation gave this Oral presentation at Pittcon 2015.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
10. Propofol
Strength 10 mg/ml (1%) amp=20ml
Compatibility Does not need to be diluted
Dilution 500 mg (2.5 amp) Total 50 ml
Concentration 10 mg / ml
Dose
Initial dose (0.3 mg/kg)
Maintenance infusion: 0.3 to 3 mg/kg/hour
Stability
If transferred to a syringe or other container prior to
administration, use within 6 hours.
If diluted in 5% dextrose stable for 8 hours at room
temperature
Dose (mg) WT(kg)
30 40 50 60 70 80 90 100
Infusion Rates ml/ hr
0.3 0.9 1.2 1.5 1.8 2.1 2.4 2.7 3
0.4 1.2 1.6 2 2.4 2.8 3.2 3.6 4
0.5 1.5 2 2.5 3 3.5 4 4.5 5
0.75 2.25 3 3.75 4.5 5.25 6 6.75 7.5
1 3 4 5 6 7 8 9 10
1.25 3.75 5 6.25 7.5 8.75 10 11.25 12.5
1.5 4.5 6 7.5 9 10.5 12 13.5 15
1.75 5.25 7 8.75 10.5 12.25 14 15.75 17.5
2 6 8 10 12 14 16 18 20
2.25 6.75 9 11.25 13.5 15.75 18 20.25 22.5
2.5 7.5 10 12.5 15 17.5 20 22.5 25
2.75 8.25 11 13.75 16.5 19.25 22 24.75 27.5
3 9 12 15 18 21 24 27 30
11. Insulin Infusion Protocol
1. Standard infusion: 50 Units Regular insulin/50 mL NS via an infusion device
2. For most patients, the goal BG should be between 90-140 mg/dL.
3. Initiating the Infusion:
Algorithm 1: Start here for most patients.
Algorithm 2: Start here if the patient has a glucose > 600 mg/dL, is in diabetic ketoacidosis, or
is s/p CABG, s/p solid organ transplant, receiving glucocorticoids, or patient with diabetes
receiving over 80 units/day of insulin as an outpatient, has a BMI more then 35, or is pregnant.
Algorithms 3-8: Do not start patients in these algorithms.
4. Patient Monitoring:
Hourly monitoring is indicated for most critically ill patients.
For stable patients, check BG every hour until it is within goal range (90 – 140 mg/dL) for 4
hours, then decrease BG checks to every 2 hours.
6. Moving down from Algorithm to Algorithm When glucose decreases >60 mg/dl in 1 hour
Blood Glucose Adjustment
BG < 60 mg/dL Treatment of Hypoglycemia
BG 61-90 mg/dL Turn off the infusion and recheck BG every 1 hour
until> 90 mg/dL and then restart infusion in next
Lower algorithm
BG between 90 and 140 mg/dL (goal) Adjust the rate within the SAME algorithm
BG between 141 and 180 mg/dL and decreased by
30 mg/dL or more
Adjust the rate within the SAME algorithm
BG between 141 and 180 mg/dL and did not
decrease by at least 30 mg/dL
Adjust the rate to the next HIGHER algorithm
BG > 180 mg/dL and decreased by 60 mg/dL or
more
Adjust the rate within the SAME algorithm
BG > 180 mg/dL and did not decrease by at least 60
mg/dL
Adjust the rate to the next HIGHER algorithm
Blood Glucose
(mg/dl)
Scale 1
(ml/hr)
Scale 2
(ml/hr)
Scale 3
(ml/hr)
Scale 4
(ml/hr)
Scale 5
(ml/hr)
Scale 6
(ml/hr)
Scale 7
(ml/hr)
Scale 8
(ml/hr)
≥400 3 4 5 6 7 8 10 11
320-399 2.5 3.5 4 5 6 6 8 9
250-319 2 3 3 4 5 5 6 7
210-249 1.5 2.5 2.5 3 4 4 4 5
180-209 1 2 2 2 3 3 3 4
140-179 1 1.5 1.5 1.5 2 2 2.5 3
110-139 0.5 1 1 1 1.5 1.5 2 2
90-109 0.5 0.5 0.5 1 1 1 1.5 1.5
<90 Stop IV insulin infusion and inform doctor
