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contains axons that arise in the
ο‚ž oculomotor nucleus (which innervates all of
  the oculomotor muscles except the superior
  oblique and lateral rectus)
ο‚ž Edinger–Westphal nucleus (which sends
  preganglionic parasympathetic axons to the
  ciliary ganglion).
ο‚ž leaves the brain on the medial side of the
  cerebral peduncle, behind the posterior
  cerebral artery and in front of the superior
  cerebellar artery.
ο‚ž then passes anteriorly, parallel to the
  internal carotid artery in the lateral wall of
  the cavernous sinus, leaving the cranial
  cavity by way of the superior orbital fissure.
ο‚ž Thesomatic efferent portion of the nerve
 innervates the levator palpebrae superioris
 muscle; the superior, medial, and inferior
 rectus muscles; and the inferior oblique
 muscle
ο‚ž Thevisceral efferent portion innervates two
 smooth intraocular muscles: the ciliary and
 the constrictor pupillae.
ο‚ž Strabismus   (squint) is the deviation of one
  or both eyes.
ο‚ž In internal strabismus, the visual axes cross
  each other
ο‚ž in external strabismus, the visual axes
  diverge from each other
ο‚ž Diplopia (double vision) is a subjective
  phenomenon reported to be present when
  the patient is, usually, looking with both eyes
ο‚ž caused by misalignment of the visual axes
ο‚ž Ptosis (lid drop) is caused by weakness or
  paralysis of the levator palpebrae superioris
  muscle
ο‚ž seen with lesions of nerve III and sometimes
  in patients with myasthenia gravis.
ο‚ž External  ophthalmoplegia is characterized
  by divergent strabismus, diplopia, and ptosis.
ο‚ž The eye deviates downward and outward.
ο‚ž This corresponds to the weaknesses of the
  medial, superior, and inferior recti and the
  inferior oblique muscles.
ο‚ž position of the eye is described by the
  mnemonic "down and out."
ο‚ž Internal ophthalmoplegia is characterized
  by a dilated pupil and loss of light and
  accommodation reflexes.
ο‚ž There may be paralysis of individual muscles
  of nerve III
ο‚ž Isolatedinvolvement of nerve III (often with
 a dilated pupil) occurs as an early sign in
 uncal herniation because of expanding
 hemispheric mass lesions that compress the
 nerve against the tentorium
ο‚ž Nerve  III crosses the internal carotid, where
  it joins the posterior communicating artery;
  aneurysms of the posterior communicating
  artery thus can compress the nerve
ο‚ž Isolated nerve III palsy also occurs in
  diabetes, presumably because of ischemic
  damage, and when caused by diabetes, often
  spares the pupil
ο‚ž the  only crossed cranial nerve
ο‚ž originates from the trochlear nucleus, which
  is a group of specialized motor neurons
  located just caudal to the CN III nucleus
  within the lower midbrain.
ο‚ž Axons  cross within the midbrain, and then
  emerge contralaterally on the dorsal surface
  of the brain stem.
ο‚ž nerve then curves ventrally between the
  posterior cerebral and superior cerebellar
  arteries (lateral to CN III).
ο‚ž continues anteriorly in the lateral wall of the
  cavernous sinus and enters the orbit via the
  superior orbital fissure.
ο‚ž innervates the superior oblique muscle
ο‚ž rare condition
ο‚ž slight convergent strabismus and diplopia on
  looking downward
ο‚ž patient cannot look downward and inward -
  has difficulty in descending stairs.
ο‚ž head is tilted as a compensatory adjustment;
  this may be the first indication of a trochlear
  lesion.
ο‚ž arises from neurons of the abducens nucleus
  located within the dorsomedial tegmentum
  within the caudal pons.
ο‚ž emerges from the pontomedullary fissure,
  passes through the cavernous sinus close to
  the internal carotid, and exits from the
  cranial cavity via the superior orbital fissure
ο‚ž long intracranial course makes it vulnerable
  to pathologic processes in the posterior and
  middle cranial fossae.
ο‚ž innervates the lateral rectus muscle
ο‚ž few  proprioceptive fibers from the muscles
  of the eye are present in nerves III, IV, and VI
  and in some other nerves that innervate
  striated muscles.
ο‚ž central termination of these fibers is in the
  mesencephalic nucleus of V
ο‚ž most common owing to the long course of
  nerve VI.
ο‚ž weakness of eye abduction
ο‚ž convergent strabismus and diplopia.
ο‚ž affected eye deviates medially, i.e., in the

  direction of the opposing muscle
Cranial nerves iii, iv,vi
Cranial nerves iii, iv,vi

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Cranial nerves iii, iv,vi

  • 1.
  • 2.
  • 3.
  • 4.
  • 5. contains axons that arise in the ο‚ž oculomotor nucleus (which innervates all of the oculomotor muscles except the superior oblique and lateral rectus) ο‚ž Edinger–Westphal nucleus (which sends preganglionic parasympathetic axons to the ciliary ganglion).
  • 6. ο‚ž leaves the brain on the medial side of the cerebral peduncle, behind the posterior cerebral artery and in front of the superior cerebellar artery. ο‚ž then passes anteriorly, parallel to the internal carotid artery in the lateral wall of the cavernous sinus, leaving the cranial cavity by way of the superior orbital fissure.
  • 7. ο‚ž Thesomatic efferent portion of the nerve innervates the levator palpebrae superioris muscle; the superior, medial, and inferior rectus muscles; and the inferior oblique muscle
  • 8. ο‚ž Thevisceral efferent portion innervates two smooth intraocular muscles: the ciliary and the constrictor pupillae.
  • 9. ο‚ž Strabismus (squint) is the deviation of one or both eyes. ο‚ž In internal strabismus, the visual axes cross each other ο‚ž in external strabismus, the visual axes diverge from each other
  • 10. ο‚ž Diplopia (double vision) is a subjective phenomenon reported to be present when the patient is, usually, looking with both eyes ο‚ž caused by misalignment of the visual axes
  • 11. ο‚ž Ptosis (lid drop) is caused by weakness or paralysis of the levator palpebrae superioris muscle ο‚ž seen with lesions of nerve III and sometimes in patients with myasthenia gravis.
  • 12. ο‚ž External ophthalmoplegia is characterized by divergent strabismus, diplopia, and ptosis. ο‚ž The eye deviates downward and outward. ο‚ž This corresponds to the weaknesses of the medial, superior, and inferior recti and the inferior oblique muscles. ο‚ž position of the eye is described by the mnemonic "down and out."
  • 13. ο‚ž Internal ophthalmoplegia is characterized by a dilated pupil and loss of light and accommodation reflexes. ο‚ž There may be paralysis of individual muscles of nerve III
  • 14.
  • 15. ο‚ž Isolatedinvolvement of nerve III (often with a dilated pupil) occurs as an early sign in uncal herniation because of expanding hemispheric mass lesions that compress the nerve against the tentorium
  • 16. ο‚ž Nerve III crosses the internal carotid, where it joins the posterior communicating artery; aneurysms of the posterior communicating artery thus can compress the nerve ο‚ž Isolated nerve III palsy also occurs in diabetes, presumably because of ischemic damage, and when caused by diabetes, often spares the pupil
  • 17. ο‚ž the only crossed cranial nerve ο‚ž originates from the trochlear nucleus, which is a group of specialized motor neurons located just caudal to the CN III nucleus within the lower midbrain.
  • 18. ο‚ž Axons cross within the midbrain, and then emerge contralaterally on the dorsal surface of the brain stem. ο‚ž nerve then curves ventrally between the posterior cerebral and superior cerebellar arteries (lateral to CN III).
  • 19. ο‚ž continues anteriorly in the lateral wall of the cavernous sinus and enters the orbit via the superior orbital fissure. ο‚ž innervates the superior oblique muscle
  • 20. ο‚ž rare condition ο‚ž slight convergent strabismus and diplopia on looking downward ο‚ž patient cannot look downward and inward - has difficulty in descending stairs. ο‚ž head is tilted as a compensatory adjustment; this may be the first indication of a trochlear lesion.
  • 21. ο‚ž arises from neurons of the abducens nucleus located within the dorsomedial tegmentum within the caudal pons. ο‚ž emerges from the pontomedullary fissure, passes through the cavernous sinus close to the internal carotid, and exits from the cranial cavity via the superior orbital fissure
  • 22.
  • 23. ο‚ž long intracranial course makes it vulnerable to pathologic processes in the posterior and middle cranial fossae. ο‚ž innervates the lateral rectus muscle
  • 24. ο‚ž few proprioceptive fibers from the muscles of the eye are present in nerves III, IV, and VI and in some other nerves that innervate striated muscles. ο‚ž central termination of these fibers is in the mesencephalic nucleus of V
  • 25. ο‚ž most common owing to the long course of nerve VI. ο‚ž weakness of eye abduction ο‚ž convergent strabismus and diplopia. ο‚ž affected eye deviates medially, i.e., in the direction of the opposing muscle