The document discusses Sars-Cov-2 and Covid-19. It provides statistics on cases globally and in India. It describes the virus, including that it is a coronavirus similar to SARS. It discusses WHO declaring Covid-19 a public health emergency. It outlines symptoms, high risk groups, diagnosis methods, clinical management including drugs like hydroxychloroquine and remdesivir, and steps to take if experiencing symptoms.
In this PowerPoint presentation you can get data about every aspect of COVID-19 disease.I gave every minute important detail in short form so that you can easily get that. Coronavirus disease spread globally and WHO called it as a Pandemic Disease on March 11,2020. in India it is on stage 2,please its my request to everyone stay at Home..Don't Go outside...Government provide everything which is of daily use...Don't Panic...Stay Safe..Stay At Home...Quarantine yourself for somedays.
Features, Evaluation and Treatment Coronavirus (COVID-19)
The WHO and other organizations have issued the following general recommendations:
Avoid close contact with subjects suffering from acute respiratory infections.
Wash your hands frequently, especially after contact with infected people or their environment.
Avoid unprotected contact with farm or wild animals.
People with symptoms of acute airway infection should keep their distance, cover coughs or sneezes with disposable tissues or clothes and wash their hands.
Strengthen, in particular, in emergency medicine departments, the application of strict hygiene measures for the prevention and control of infections.
Individuals that are immunocompromised should avoid public gatherings.
Patients and families should receive instruction to:
Avoid close contact with subjects suffering from acute respiratory infections.
Wash their hands frequently, especially after contact with sick people or their environment.
Avoid unprotected contact with farm or wild animals.
People with symptoms of acute airway infection should keep their distance, cover coughs or sneezes with disposable tissues or clothes and wash their hands.
Immunocompromised patients should avoid public exposure and public gatherings. If an immunocompromised individual must be in a closed space with multiple individuals present, such as a meeting in a small room; masks, gloves, and personal hygiene with antiseptic soap should be undertaken by those in close contact with the individual. In addition, prior room cleaning with antiseptic agents should be undertaken and performed before exposure. However, considering the danger involved to these individuals, exposure should be avoided unless a meeting, group event, etc. is a true emergency.
Strict personal hygiene measures are necessary for the prevention and control of this infection.
coronavirus disease (COVID-19),origin,epidemiology,risk factors and causes,mode of transmission,pathophysiology,signs and symptoms,management,comlication,preventive measures
Rekha Dehariya (M.Sc nursing 1st year) Bhopal Nursing College, Bhopal
Covid -19 has effected broud number of people all over the world. the health education is necessary to aware people about it.
In this PowerPoint presentation you can get data about every aspect of COVID-19 disease.I gave every minute important detail in short form so that you can easily get that. Coronavirus disease spread globally and WHO called it as a Pandemic Disease on March 11,2020. in India it is on stage 2,please its my request to everyone stay at Home..Don't Go outside...Government provide everything which is of daily use...Don't Panic...Stay Safe..Stay At Home...Quarantine yourself for somedays.
Features, Evaluation and Treatment Coronavirus (COVID-19)
The WHO and other organizations have issued the following general recommendations:
Avoid close contact with subjects suffering from acute respiratory infections.
Wash your hands frequently, especially after contact with infected people or their environment.
Avoid unprotected contact with farm or wild animals.
People with symptoms of acute airway infection should keep their distance, cover coughs or sneezes with disposable tissues or clothes and wash their hands.
Strengthen, in particular, in emergency medicine departments, the application of strict hygiene measures for the prevention and control of infections.
Individuals that are immunocompromised should avoid public gatherings.
Patients and families should receive instruction to:
Avoid close contact with subjects suffering from acute respiratory infections.
Wash their hands frequently, especially after contact with sick people or their environment.
Avoid unprotected contact with farm or wild animals.
People with symptoms of acute airway infection should keep their distance, cover coughs or sneezes with disposable tissues or clothes and wash their hands.
Immunocompromised patients should avoid public exposure and public gatherings. If an immunocompromised individual must be in a closed space with multiple individuals present, such as a meeting in a small room; masks, gloves, and personal hygiene with antiseptic soap should be undertaken by those in close contact with the individual. In addition, prior room cleaning with antiseptic agents should be undertaken and performed before exposure. However, considering the danger involved to these individuals, exposure should be avoided unless a meeting, group event, etc. is a true emergency.
Strict personal hygiene measures are necessary for the prevention and control of this infection.
coronavirus disease (COVID-19),origin,epidemiology,risk factors and causes,mode of transmission,pathophysiology,signs and symptoms,management,comlication,preventive measures
Rekha Dehariya (M.Sc nursing 1st year) Bhopal Nursing College, Bhopal
Covid -19 has effected broud number of people all over the world. the health education is necessary to aware people about it.
The Corona virus pandemic has costed a lot of lives through out the world.
Here are some in formations about what is known so far.
It includes cause, Spread, Signs and Symptoms.
it also has the ongoing myths about corona virus.
COVID-19 (coronavirus disease 2019) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), previously known as 2019 novel coronavirus (2019-nCoV), a strain of coronavirus. The first cases were seen in Wuhan, China in December 2019 before spreading globally. The current outbreak was recognized as a pandemic on 11 March 2020.
The non-specific imaging findings are most commonly of atypical or organizing pneumonia, often with a bilateral, peripheral, and basal predominant distribution. No effective treatment or vaccine exists currently (March 2020).
Novel corona virus (COVID-19) its cause, symptoms and treatmentMedical Knowledge
In this SlideShare, you can learn about the pandemic Novel Corona Virus (COVID-19) and also seek knowledge about,
1. What is Coronavirus?
2. Types of the Coronavirus.
3. Transmission of Coronavirus.
4. Prevention of Coronavirus.
5. Treatment of Coronavirus.
6. Diet in Coronavirus.
7. Symptoms of Coronavirus.
8. How Coronavirus get its name?
9. What is MERS_COVID & SARS_COVID?
To download the PowerPoint of this click below:
https://drive.google.com/open?id=1s35dGMbsaO8WT2RG8NudOBc4lF2u5JXyH0MVQWpiaXk
To view the video tutorial click below:
https://youtu.be/sKVFN250l_Q
This Powerpoint presentation is on Covid-19. It includes the origin of Covid 19, features, figures in the world, role of common people, role of Government, art of living due to lockdown, outcomes and lessons of Covid-19 and lockdown, and how to tackle such situations in future.
Coronaviruses are a group of related viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold, and others that can be lethal, such as SARS, MERS, and COVID-19. Symptoms in other species vary: in chickens, they cause an upper respiratory tract disease, while in cows and pigs they cause diarrhea. There are yet to be vaccines or antiviral drugs to prevent or treat human coronavirus infections.
COVID-19 : Introduction,Nomenclature,Incubation Period,Structure,Symptoms,Transmission,Flowchart,Diagnosis,Treatment,Drugs under testing,Prevention,Importance of Social Distancing,Effects in Lungs,Effects in Other organs,Replication,Severity,Stages,Comparison,Facts.
Coronavirus presentation by Leyla RashidliAzer Rashidov
Today,I've done a presentation for students about most important health issue in our community,that is called Middle East Respiratory Syndrome-Coronavirus(MERS-CoV).
“You can download this product from SlideTeam.net”
Spread awareness about the pandemic using the impressive visuals of our Corona Virus Disease 19 Powerpoint Presentation Slides. The easy-to-follow content of coronavirus PPT theme assists you to convey information to the audience of all ages, shapes, and sizes. This COVID 19 PowerPoint slideshow will help you explain the age risk factors, symptoms, and prevention methods concisely. Impactful data visualization tools like infographics in this novel coronavirus pneumonia PPT template enables you to effortlessly demonstrate sophisticated data. Compare the spread, incubation rate of coronavirus against other pandemics, and portray mortality rate through this corona PowerPoint presentation. Present crucial information like how long the virus lasts on different surfaces, and risk factors through this COVID PPT slideshow. Our 2019-nCoV acute respiratory disease PowerPoint theme helps you to illustrate the outbreak of the pandemic continent-wise. Download severe pneumonia with novel pathogens PPT template to explain crucial information related to the pandemic like effects on the stock market. https://bit.ly/3IN6j4F
To Assess the Severity and Mortality among Covid 19 Patients after Having Vac...YogeshIJTSRD
The severity and mortality of COVID 19 cases has been associated with the Three category such as vaccination status, severity of disease and outcome. Objective presently study was aimed to assess the severity and mortality among covid 19 patients. Methods Using simple lottery random method 100 samples were selected. From these 100 patients, 50 patients were randomly assigned to case group and 50 patients in control group after informed consents of relative obtained. Patients in the case group who being died after got COVID 19 whereas 50 patients in the control group participated who were survive after got infected from COVID 19 patients. Result It has three categories such as a Vaccination status For the vaccination status we have seen 59 patients were not vaccinated and 41 patients was vaccinated out of 100. b Incidence There were 41 patients were vaccinated whereas 59 patients were not vaccinated. c Severity In the case of mortality we selected 50 patients who were died from the Corona and I got to know that out of 50 patients there were 12 24 patients were vaccinated whereas 38 76 patients were non vaccinated. Although for the 50 control survival group total 29 58 patients were vaccinated and 21 42 patients was not vaccinated all graph start. Conclusion we have find out that those people who got vaccinated were less infected and mortality rate very low. Prof. (Dr) Binod Kumar Singh | Dr. Saroj Kumar | Ms. Anuradha Sharma "To Assess the Severity and Mortality among Covid-19 Patients after Having Vaccinated: A Retrospective Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45065.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/45065/to-assess-the-severity-and-mortality-among-covid19-patients-after-having-vaccinated-a-retrospective-study/prof-dr-binod-kumar-singh
The Corona virus pandemic has costed a lot of lives through out the world.
Here are some in formations about what is known so far.
It includes cause, Spread, Signs and Symptoms.
it also has the ongoing myths about corona virus.
COVID-19 (coronavirus disease 2019) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), previously known as 2019 novel coronavirus (2019-nCoV), a strain of coronavirus. The first cases were seen in Wuhan, China in December 2019 before spreading globally. The current outbreak was recognized as a pandemic on 11 March 2020.
The non-specific imaging findings are most commonly of atypical or organizing pneumonia, often with a bilateral, peripheral, and basal predominant distribution. No effective treatment or vaccine exists currently (March 2020).
Novel corona virus (COVID-19) its cause, symptoms and treatmentMedical Knowledge
In this SlideShare, you can learn about the pandemic Novel Corona Virus (COVID-19) and also seek knowledge about,
1. What is Coronavirus?
2. Types of the Coronavirus.
3. Transmission of Coronavirus.
4. Prevention of Coronavirus.
5. Treatment of Coronavirus.
6. Diet in Coronavirus.
7. Symptoms of Coronavirus.
8. How Coronavirus get its name?
9. What is MERS_COVID & SARS_COVID?
To download the PowerPoint of this click below:
https://drive.google.com/open?id=1s35dGMbsaO8WT2RG8NudOBc4lF2u5JXyH0MVQWpiaXk
To view the video tutorial click below:
https://youtu.be/sKVFN250l_Q
This Powerpoint presentation is on Covid-19. It includes the origin of Covid 19, features, figures in the world, role of common people, role of Government, art of living due to lockdown, outcomes and lessons of Covid-19 and lockdown, and how to tackle such situations in future.
Coronaviruses are a group of related viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold, and others that can be lethal, such as SARS, MERS, and COVID-19. Symptoms in other species vary: in chickens, they cause an upper respiratory tract disease, while in cows and pigs they cause diarrhea. There are yet to be vaccines or antiviral drugs to prevent or treat human coronavirus infections.
COVID-19 : Introduction,Nomenclature,Incubation Period,Structure,Symptoms,Transmission,Flowchart,Diagnosis,Treatment,Drugs under testing,Prevention,Importance of Social Distancing,Effects in Lungs,Effects in Other organs,Replication,Severity,Stages,Comparison,Facts.
Coronavirus presentation by Leyla RashidliAzer Rashidov
Today,I've done a presentation for students about most important health issue in our community,that is called Middle East Respiratory Syndrome-Coronavirus(MERS-CoV).
“You can download this product from SlideTeam.net”
Spread awareness about the pandemic using the impressive visuals of our Corona Virus Disease 19 Powerpoint Presentation Slides. The easy-to-follow content of coronavirus PPT theme assists you to convey information to the audience of all ages, shapes, and sizes. This COVID 19 PowerPoint slideshow will help you explain the age risk factors, symptoms, and prevention methods concisely. Impactful data visualization tools like infographics in this novel coronavirus pneumonia PPT template enables you to effortlessly demonstrate sophisticated data. Compare the spread, incubation rate of coronavirus against other pandemics, and portray mortality rate through this corona PowerPoint presentation. Present crucial information like how long the virus lasts on different surfaces, and risk factors through this COVID PPT slideshow. Our 2019-nCoV acute respiratory disease PowerPoint theme helps you to illustrate the outbreak of the pandemic continent-wise. Download severe pneumonia with novel pathogens PPT template to explain crucial information related to the pandemic like effects on the stock market. https://bit.ly/3IN6j4F
To Assess the Severity and Mortality among Covid 19 Patients after Having Vac...YogeshIJTSRD
The severity and mortality of COVID 19 cases has been associated with the Three category such as vaccination status, severity of disease and outcome. Objective presently study was aimed to assess the severity and mortality among covid 19 patients. Methods Using simple lottery random method 100 samples were selected. From these 100 patients, 50 patients were randomly assigned to case group and 50 patients in control group after informed consents of relative obtained. Patients in the case group who being died after got COVID 19 whereas 50 patients in the control group participated who were survive after got infected from COVID 19 patients. Result It has three categories such as a Vaccination status For the vaccination status we have seen 59 patients were not vaccinated and 41 patients was vaccinated out of 100. b Incidence There were 41 patients were vaccinated whereas 59 patients were not vaccinated. c Severity In the case of mortality we selected 50 patients who were died from the Corona and I got to know that out of 50 patients there were 12 24 patients were vaccinated whereas 38 76 patients were non vaccinated. Although for the 50 control survival group total 29 58 patients were vaccinated and 21 42 patients was not vaccinated all graph start. Conclusion we have find out that those people who got vaccinated were less infected and mortality rate very low. Prof. (Dr) Binod Kumar Singh | Dr. Saroj Kumar | Ms. Anuradha Sharma "To Assess the Severity and Mortality among Covid-19 Patients after Having Vaccinated: A Retrospective Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45065.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/45065/to-assess-the-severity-and-mortality-among-covid19-patients-after-having-vaccinated-a-retrospective-study/prof-dr-binod-kumar-singh
Cyclosporine Attenuates Covid-19: Ensnare or Victorypateldrona
Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS). It has been proposed that initial immunological activation in SARSCoV- 2...
Cyclosporine Attenuates Covid-19: Ensnare or Victoryclinicsoncology
Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS). It has been proposed that initial immunological activation in SARSCoV- 2...
Abstract Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS)
Cyclosporine Attenuates Covid-19: Ensnare or Victorykomalicarol
Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury
(ALI) due to severe acute respiratory distress syndrome (ARDS). It
has been proposed that initial immunological activation in SARSCoV-2 infection is necessary for elimination and clearance of viral
infection; however exaggerated late immune response is associated with immunological-mediated tissue injury
Cyclosporine Attenuates Covid-19: Ensnare or VictorySarkarRenon
Abstract Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS).
Cyclosporine Attenuates Covid-19: Ensnare or Victorygeorgemarini
Coronavirus disease 2019 (Covid-19) is a recent worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In critical cases it causes acute lung injury (ALI) due to severe acute respiratory distress syndrome (ARDS). It has been proposed that initial immunological activation in SARSCoV- 2...
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. The new coronavirus that jumped from some animal to a person in the city of
Wuhan at the end of last year has managed, in only a few weeks, to draw huge
attention from the media, scientists and the international community. On
January 30, the WHO declared the epidemic a Public health emergency of
international concern (PHEIC).
At present around 12 064 828+ cases of coronavirus disease 2019 (COVID-
19) and
550 384 deaths have been reported around the world.
India has reported 794K+ cases and 21,604 deaths till date.
introduction
3. The new coronavirus, first called 2019–nCoV and officially renamed as SARS-
CoV2 (the virus) and COVID-19 (the disease), belongs to the family of coronavirus,
the name to crown-like spikes on their surface. Most described coronavirus are found in
birds or mammals, particularly bats.
The new coronavirus is called SARS-CoV2 because its genetic sequence is very similar to
that of SARS, another coronavirus that appeared for first (and only) time in 2002 and
caused a pandemic with more than 8,000 infected people and 800 deaths.
Another coronavirus that causes severe disease in humans is MERS-CoV, identified for
the first time in 2012 in the Middle East and associated with camels.
5. Stats about covid-19 in india
Active Cases
Cured/Discharged
Deaths
0
100,000
200,000
300,000
400,000
500,000
600,000
700,000
800,000
900,000
Apr-30 May-31 Jun-30 Jul-12
35,433
190,523
585362
878190
8949
91598
347921
553856
1142 5357 17311 23225
Active Cases Cured/Discharged Deaths
6. High Risk Groups
COVID-19 is peculiar in its disproportionate case fatality rates among patients >60
years as opposed to young adults or pediatric population.
The highest mortality rates were seen among individuals above 80 yr of age at 14.8
per cent.
While further research is going on, the data suggests that tobacco smoking is also a
risk factor for COVID-19. Smokers (both former and current) are more likely to have
severe symptoms, are admitted to intensive care unit (ICU), need mechanical
ventilation or die compared to non-smokers.
7. Comorbid illness and case fatality rates in high-risk groups
Age, year (case fatality rate, %) Comorbid illness (case fatality rate, %)
60-70 (4)
>70-80 (8)
>80 (15)
Cardiovascular disease (10.5)
Diabetes mellitus (7.3)
Chronic respiratory disease (6.3)
Systemic hypertension (6.0)
Cancer (5.6)
The high-risk groups and age-wise case fatality rates are depicted in
above table
NOTE: case fatality rate is the proportion of deaths from a certain
disease compared to the total number of people diagnosed with the
disease for a certain period of time.
8. A person can contract COVID-19 if:
● They come in contact with another person infected with the virus
● Someone infected coughs or sneezes directly to them
● They touch any surface with little droplets from infected people’s
cough or sneezes and then touch their eyes, nose or mouth
HOW do YOU
get COVID-19?
9. Clinicalfeatures
C l i n i c a l f e a t u r e s
The incubation period of COVID-19 is 1-14
days (mean duration of 5-7 days), with peak
viraemia occurring before the onset of
symptoms.
The most common presenting features of
COVID-19 infection are listed below:
Symptoms (frequency in %)
Fever (80-90)
Cough (60-80)
Breathlessness (18-46)
Fatigue (38)
Body ache/joint pain (15)
Sore throat (11-14)
Headache (6-14)
Chills (12)
Running nose (5)
Nausea/vomiting (5)
Diarrhea (2-10)
10. Warningsigns
Warning signs or red flag signs that can assist in
triage, indicating the need for urgent
care/hospitalization, are listed below:
Wa r n i n g s i g n s
Fever and upper respiratory symptoms lasting
for >5 days and any of the following:
1. Breathlessness/respiratory rate >24/min
2. Oxygen saturation (SpO2 )
3. 110/bpm Systolic blood pressure
E M E R G E N C Y
11. COVID nucleic acid test positive. Without
any clinical symptoms and signs and the
chest imaging is normal.
A s y m p t o m a t i c c o n d i t i o n
12. Categorization of probable coronavirus disease 2019 (COVID-19) severity, testing and admission strategy
Clinical category of
COVID-19
Features Testing strategy Level of care
Mild Fever with upper respiratory symptoms
Mild sore throat and GI symptoms
Testing may be considered in select individuals
individuals in the high-risk group
Low priority Home care
Moderate Breathlessness/respiratory rate >24/min
Oxygen saturation (SpO2) <95% in room air
Fatigue with heart rate of >110/bpm
Systolic blood pressure <90 mmHg
High priority Inpatient care
Severe SpO2 <90% in room air
Hypotension requiring ionotropic support
ARDS/myocarditis
High priority Intensive care
13. Steps to be followed if you have symptoms
You have symptoms or
have been in an infected
area
STEP 01
Call the designated phone
number for your region
STEP 02
You will be given a home
test over the phone
STEP 03
16. diagnosis
d i a g n o s i s
1. Travel history to endemic countries
2. CBC (leukopenia, seen in 30% to 45% of
patients, and lymphocytopenia, seen in 85% of
the patients)
3. Chest X-Ray (cheaper & easier with 60%
sensitivity)
4. PCR (30%-70% sensitivity)
5. Chest CT Scan (95% sensitivity, low specificity)
6. IgM/IgG combo test for COVID-19
19. Management
1. Hydroxychloroquine:
The 4-aminoquinolone, commonly used as an antimalarial and anti-inflammatory agent, possesses broad antiviral
activity. While the exact mechanisms are unknown, it is considered to gain its antiviral effects through
alkalinization of the phagolysosome as well as inhibition of viral entry by blocking receptor binding and
membrane fusion. With a similar mechanism of action, hydroxychloroquine (HCQ) has demonstrated more potent
in vitro inhibition of SARS-CoV-2 virus compared to chloroquine.
Its fewer side effects, safety in pregnancy and inexpensive nature makes it more preferable to chloroquine
If chosen for the treatment of confirmed COVID-19, the dose of HCQ suggested is 400 mg twice a day (bd) for one
day followed by 200 mg (bd) for 5-10 days.
ADRS: Nausea, vomiting, loss of appetite, diarrhea, dizziness, or headache
At present, the role of specific antiviral medication is at best adjunctive in nature. The following drugs
have shown some promise for the management of COVID-19
20. 2. Lopinavir/ritonavir:
A boosted protease inhibitor combination, while commonly used in the treatment of HIV-1
infection, came into spotlight during the SARS outbreak in 2003
the lopinavir arm had numerically lesser deaths and ventilator days. However, the drug did not
reduce the viral loads when compared to the control arm.
The dose used was lopinavir 400 mg-ritonavir 100 mg twice a day for 14 days
3. Oseltamivir:
A neuroaminidase inhibitor, is a pivotal drug in influenza management. It has not been shown
to have activity for CoVs due to lack of neuraminidase and is hence unlikely to be of benefit.
Though it was used in the earlier part of the epidemic in China, it is no longer recommended by
most guidelines
Management
21. 4. Remdesivir:
It is an adenosine analogue and RNA polymerase blocker, is a novel drug developed for the treatment of
Ebola virus infection. A randomized control trial on remdesivir in severe COVID-19 patients did not show
any significant benefit.
However, there was a trend towards shortened illness in patients who received the drug early. While the
drug is available in different countries through multiple clinical trials, it is also being provided by the
manufacturers on a compassionate use basis. In view of its broad antiviral properties, safety profile from
Ebola studies and in vitro activity against SARS-CoV-2, remdesivir is considered as a promising agent.
A recent case series of the drug in a compassionate use programme in COVID-19 patients with hypoxemia
showed clinical improvement in two-thirds of the patients.
5. Favipiravir:
It is an a RNA polymerase inhibitor, has shown modest activity against SARS-CoV-2 virus with
pronounced cytopathy in Vero cell studies
The drug has been used in China for the treatment of COVID-19 and is being studied in a clinical trial for
mild SARS-CoV-2 disease and also as an adjunct agent in moderate and severe diseases
Management
22. 6. Interleukin-6 (IL-6) inhibitors
A subgroup of patients with COVID-19 develop severe cytokine activation and secondary
haemophagocytic lymphohistiocytosis (HLH), leading to rapid-onset hypoxemia, shock and
multiorgan dysfunction. A higher neutrophil count and elevated C-reactive protein may predict
this subgroup of patients.
Interleukin-6 (IL-6) is a key cytokine in the cytokine storm, and tocilizumb, a humanized anti-
IL-6 receptor antibody, is proposed as a therapeutic agent in severe SARS-CoV-2 disease.
In a small series of 21 patients with severe or critical COVID-19 from China, tocilizumab showed
marked improvement in hypoxia, chest imaging, fever, lymphocyte counts and C-reactive
protein.
7. Corticosteroids:
These are generally not useful against similar severe respiratory viral illnesses such as SARS or
Middle East respiratory syndrome (MERS)-CoV disease.
A recent retrospective review showed decreased likelihood of death among patients with SARS-
CoV-2-related acute respiratory distress syndrome (ARDS) who received methylprednisolone
Management
23. 8. Convalescent plasma from COVID-19 survivors
Uncontrolled studies during the SARS epidemic showed that convalescent plasma therapy
decreased hospital stay and mortality when used in the critically ill48. Convalescent plasma
plasma therapy was attempted with some benefit in MERS, Ebola and H1N1 pandemic
influenza49-51. A small case series of five patients with critically ill COVID-19 on mechanical
mechanical ventilation improving after receiving therapy on the third week of illness is
encouraging52. Depicted in Table V is a quick guide for adjunctive treatment strategy to be
be considered on the use of specific antivirals for the management of COVID-19 patients
depending on the clinical category and severity of illness.
Management
24. Management
Antivirals for the management of coronavirus disease 2019 (COVID-19)
Clinical category of COVID-19 Specific/antiviral therapy
Mild Symptomatic treatment
Moderate* Tablet hydroxychloroquine 400 mg bd × 1 day
followed by 200 mg bd × 10 days
Severe* Tablet hydroxychloroquine 400 mg bd × 1 day
followed by 200 mg bd × 2 wk Tablet lopinavir
400 mg/ritonavir 100 mg bd × 2 wk *
NOTE: There is insufficient evidence for or against most of the drugs mentioned above and should
preferably be used in discussion with the patients or the next of kin. May consider new antiviral agents
agents such as remdesivir or immunomodulatory therapy such as tocilizumab in the appropriate setting
27. COVID-19 IN DIFFERENT SURFACES
SURFACE TIME
Sprayers 3 hours
Copper 4 hours
Plastic 2-3 days
SURFACE TIME
Cardboard 24 hours
Steel 2-3 days
Wood 4 days
28. Cover your mouth and your
nose with your bent elbow or
a tissue when coughing
Seek medical attention if you
have difficulty breathing and
a high fever
Follow the directions of your
national or local health
authorities
Wash your hands with an
alcohol-based sanitizer or
with soap and water
Keep a distance of at least 1
meter between yourself and
anyone who coughs or
sneezes
Try your best not to touch
your eyes, your nose and
your mouth
PROTECTING YOURSELF AND PREVENTING THE SPREAD OF
THE DISEASE
29. ● Before wearing a mask, wash your hands with an alcohol-based disinfectant or with
soap and water.
● Cover your mouth and nose with the mask and make sure the mask is firmly
pressed against your face.
● Do not touch the mask while you are wearing it; if you do, wash your hands with an
alcohol-based disinfectant or with soap and water afterward.
● Replace the mask as soon as it gets wet and do not reuse disposable masks.
● Remove the mask from behind (do not touch its front side); throw it away in a
closed container and then wash your hands with an alcohol-based disinfectant or
with soap and water.
HOW TO USE A MASK
30. Safe use of alcohol-based hand sanitizers
To protect yourself and others against COVID-19, clean your hands frequently and thoroughly. Use alcohol-based
alcohol-based hand sanitizer or wash your hands with soap and water. If you use an alcohol-based hand
sanitizer, make sure you use and store it carefully.
Keep alcohol-based hand sanitizers out of children’s reach. Teach them how to apply the sanitizer and
monitor its use.
Apply a coin-sized amount on your hands. There is no need to use a large amount of the product.
Avoid touching your eyes, mouth and nose immediately after using an alcohol-based hand sanitizer, as it can
it can cause irritation.
Hand sanitizers recommended to protect against COVID-19 are alcohol-based and therefore can
be flammable. Do not use before handling fire or cooking.
Under no circumstance, drink or let children swallow an alcohol-based hand sanitizer. It can be poisonous.
poisonous.
Remember that washing your hands with soap and water is also effective against COVID-19.
Safeuseofalcohol-basedhandsanitizers
31. PROTECTIVE MEASURES FOR PEOPLE THAT ARE IN OR
VISITED INFECTED AREAS
01 02
Stay home if you do not feel well, even if you
feel mild symptoms such as headaches, slight
fever and a runny nose
If you need to go out (for example, to buy
food or supplies), wear a mask to minimize
the risk of infecting others
03 04
If you have difficulty breathing and/or a high
fever, seek medical advice as soon as possible
Call your provider and inform them of any
recent travel, especially to countries with
reported cases