A primer on available evidence and management of Covid -19 infection, with system wise pathophysiology and therapeutic strategies. Perspective of intensive care, with specific information and tips on intubation and ventilatory management of these patients. Focus on severe infections, and various manifestations. Serious symptoms: difficulty breathing or shortness of breath chest pain or pressure loss of speech or movement Seek immediate medical attention if you have serious symptoms. Always call before visiting your doctor or health facility.