The document discusses several methods for controlling particulate contaminants, including their working principles:
1) Gravity separators and centrifugal separators remove larger particles (>50 μm) from gas streams using gravitational settling or centrifugal forces.
2) Electrostatic precipitators ionize particles and collect them on oppositely charged plates, achieving high removal efficiencies of over 90% for particles over 1 μm.
3) Fabric filters and wet scrubbers like particulate scrubbers can remove over 90% of particles less than 10 μm using filtration through fabric or liquid contact. Selection depends on factors like contaminant properties, space, and costs.
Unit 3 control of particulate contaminantsChockalingam T
The attached powerpoint presentation contains information about the Control of Particulate Contaminants. It is very useful for students studiying Air Pollution and Control Engineering either as an Open elective or Professional elective.
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
Air Pollution control- at source-equipments for control of air pollution-For particulate matter-Settling chambers-Fabric filters-Scrubbers-Cyclones-Electrostatic precipitators
, For Gaseous pollutants-control by absorption-adsorption-scrubbers-secondary combustion after burners, Working principles advantages and disadvantages
Unit 3 control of particulate contaminantsChockalingam T
The attached powerpoint presentation contains information about the Control of Particulate Contaminants. It is very useful for students studiying Air Pollution and Control Engineering either as an Open elective or Professional elective.
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
Air Pollution control- at source-equipments for control of air pollution-For particulate matter-Settling chambers-Fabric filters-Scrubbers-Cyclones-Electrostatic precipitators
, For Gaseous pollutants-control by absorption-adsorption-scrubbers-secondary combustion after burners, Working principles advantages and disadvantages
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
Everyone can raise a question that how to prevent an Air pollution and so on. So here is our presentation on Control of Air pollution. So using the technique called adsorption sampling is an interesting one to all of the human beings
SBR-process (Sequencing-Batch-Reactor) is the combination of the procedural functions “Aeration” and “Clarification” in one reaction tank. Here from a stable and flexible process flow results. Furthermore the SBR-process enables a compact plant design and a minimization of the investment costs. Because of the flexible plant geometry (tanks with circular, quadratic or rectangular footprint) SBR-wastewater treatment plants of w-wwt can be simply realized also under hindered project conditions (tourism areas, recreation centers, tower buildings etc.).
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
AIR POLLUTION CONTROL course material by Prof S S JAHAGIRDAR,NKOCET,SOLAPUR for BE (CIVIL ) students of Solapur university. Content will be also useful for SHIVAJI and PUNE university students
Everyone can raise a question that how to prevent an Air pollution and so on. So here is our presentation on Control of Air pollution. So using the technique called adsorption sampling is an interesting one to all of the human beings
SBR-process (Sequencing-Batch-Reactor) is the combination of the procedural functions “Aeration” and “Clarification” in one reaction tank. Here from a stable and flexible process flow results. Furthermore the SBR-process enables a compact plant design and a minimization of the investment costs. Because of the flexible plant geometry (tanks with circular, quadratic or rectangular footprint) SBR-wastewater treatment plants of w-wwt can be simply realized also under hindered project conditions (tourism areas, recreation centers, tower buildings etc.).
- Raw Material Handling Plant
- Dust Generation & Necessity of Control
- Types of Dust Control System
- Dust Collection System
- Air Cleaning Devices
- Bag House Dust Collector
Standard particulate matter
particle pollution
air pollution and control
particulate matter
Monitoring of Particulate matter
Monitoring of air pollutants
the spray drying process involves the atomization of a solution ,slurry or emulsion containing one or more components of the desired product in to droplets by spraying followed by the rapid evaporation of the sprayed droplets in to solid powder by hot air at a certain temp and pressure.
- Raw material handling plant
- Dust generation
- Necessity of dust control
- Types of Dust Control system
- Wet Dust Suppression
- Dry fog Dust Suppression
- Types of Nozzle & Spray pattern
- Nozzle Maintenance & Performance Testing
spray drying is technology widely used in milk powder and coffee powder manufacturing industry because of its working principle and technology involved..
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
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Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
1. CONTROL OF PARTICULATE CONTAMINANTS
1. Factors affecting Selection of Control
Equipment
2. Gas Particle Interaction – Working principle
3. Gravity Separators - Working principle
4. Centrifugal separators - Working principle
5. Fabric filters - Working principle
6. Particulate Scrubbers - Working principle
7. Electrostatic Precipitators - Working principle
2. Factors affecting Selection of Control Equipment
The following factors are considered for selecting a
particular air pollution control equipment.
• Environment
• Engineering
• Economic
Environmental :
• equipment location, availability space, ambient
conditions, availability of adequate utilities and
ancillary system facilities.
• Maximum allowable emissions.
• Contribution of air pollution control system to waste
water and solid waste.
• Contribution of air pollution control system to plant
noise levels.
3. Engineering:
• Design and performance characteristics of the
particular control system(size and weight)
• Pressure drop, reliability and dependability,
temperature limitation, maintenance
requirement.
• Contaminant characteristics(physical and
chemical) properties,concentration, particulate
shape and size distribution in the case of
particulates.
• Gas stream characteristics (volume, flow rate,
temperature, pressure, humidity, composition,
reactivity, corrosiveness and toxicity).
5. • PM stands for particulate matter - particle
pollution
• It is a mixture of solid particles and liquid
droplets found in the air - Some particles, such as
dust, dirt, soot, or smoke.
• Fine particulate matter (PM2.5) is an air pollutant
- when levels in air are high.
• PM2.5 are tiny particles in the air that reduce
visibility and cause the air to appear hazy when
levels are elevated.
• Exposure to such particles can affect both your
lungs and your heart.
6. Types of particulate matter
• Inhalable coarse particles - found near
roadways and dusty industries, they are larger
than 2.5 micrometers and smaller than 10
micrometers in diameter.
• Fine particles - found in smoke and haze, and
are 2.5 micrometers in diameter and smaller.
7. steps to Reduce Exposure to Indoor PM
• Vent all fuel-fired combustion appliances to the
outdoors (including stoves, heaters and furnaces)
• Install and use exhaust fans vented to the
outside when cooking.
• Avoid the use of unvented stoves, fireplaces or
space heaters indoors.
Measurement Method :
• The most accurate measurements is gravimetric
(weighing) method. Air is drawn through a
preweighed filter, and particles collect in the
filter.
8. Gas Particle Interaction –Working
principle - Gravity Separators
• Gravitational settling chambers used to remove large particles
usually > 50 µm from gas stream.
• Particles settle under gravitational force.
• This device consists of huge rectangular chambers in which
the velocity of the carrier gas is decreased so that particles in
the gas settle down by gravity.
• The gas stream polluted with particulates is allowed to enter
from one end..
• The horizontal velocity of the gas stream is kept low in order
to give sufficient time for the particle to settle by gravity.
• The particulates having higher density obey stoke’s law and
settle at the bottom of the chamber from where they are
removed ultimately.
• Several horizontal shelves or trays improve the collection
efficiency by shortening the settling path of the particles.
9. Advantages :
Low initial cost
Easy to design
Low pressure drop
low maintenance
cost
Disadvantages
Require large space
Less collection efficiency
Only larger size particles can be
collected
10. Cyclone separators
• A simple cyclone separator consists of a cylindrical shell,
conical base, dust hopper and an inlet. An out let for
discharging the particulates is present at the base of the
cone.
• Through an inlet, the dust laden gas enters tangentially.
where the gas receives a rotating motion and generates a
centrifugal force.
• Under the influence of the centrifugal force generated by
the spinning gas, the solid particulates are thrown to the
cyclone walls as the gas spirals upwards inside the cone.
• The particulates slide down the walls of the cone and into
the hopper and are discharged from the outlet.
• It can remove 10 to 50 µm particle size.
11.
12. Disadvantages:
• Requires large head room
• Less efficiency for smaller particles
• Sensitive to variable dust load and flow rate.
Advantages :
1. Low initial cost
2. Require less floor area
3. Simple construction and maintenance
13. Electrostatic precipitator
• Electrostatic precipitator are used in removal of fly ash dust particles
from electric utility boiler emissions.
• The dust laden gas is passed between oppositely charged
conductors.
• Then it becomes ionized as the voltage applies between the
conductors.
• As the dust laden gas is passed through those highly charged
electrodes, both negative and positive ions are formed.
• The ionized gas is further passed through the collecting units.
• Which consist of a set of vertical metal plates.
• Alternate plates are positively charged and earthed.
• As the alternate plates ate earthed high intensity electrostatic field
applies a force on oppositely charged dust particles and drives them
toward the grounded plates.
• The deposited dust particles are removed from the plates by giving
the shaking motion of the plates with the help of external means.
• The dust removed from the plates with the help of shaking motion is
collected in the dust hoppers.
14.
15. Advantages:
1.high collection efficiency
2. particles may be collected dry or wet
3. can be operated at high temperature.
4. Maintenance is normal
5. few moving parts
Disadvantages:
• High initial cost
• Require high voltage
• Collection efficiency reduce with time
• Space requirement is more
16. Centrifugal Separator
• The centrifugal separator features an inlet, outlet,
and separator. The separator produces a spinning
vortex, which leads to the filtration of solids from
liquids. The separated solids are collected at the
bottom of the separator, and they are removed
from there.
• centrifugal separator is the most effective
• least expensive method for PM control.
• More than 90% dust removal efficiency
17.
18. Fabric filter
• Fabric filter remove partcles upto 1μm. FFs are typically
referred to as baghouses.
• When the flue gas is allowed to pass through a fabric,
which filters out particulate matter.
• Dust laden gas or air enters the baghouse through hoppers
then it is directed into the baghouse compartment.
• The gas is drawn through the bags, either on the inside or
outside depending on cleaning method.
• A layer of dust accumulates on the filter media surface
until air can no longer move through it.
• When sufficient pressure drop occurs, the cleaning
process begins.
• When the compartment is clean, normal filtering resumes.
19.
20. Advantages
• Higher collection efficiency for smaller than 10
μm particle size.
• High removal yield for coarse and fine dust.
• Varying load does not influence pressure drop
and efficiency.
• Collected dust can possibly be re-used in the
process.
• Residual emissions are determined by incoming
concentrations.
• Relatively easy to use.
21. Disadvantages:
• High temperature gases need to be cooled
• High maintenance and fabric replacement cost
• Large size equipment
• Fabric is liable to chemical attack.
22. Particulate Scrubbers:
• Particulate scrubber is a low energy scrubber and is
the simplest wet scrubber used for particulate
control.
• A particulate scrubber is a scrubber in which a liquid
is mixed with the gas to collect solids.
• In particulate scrubbers, the liquid is dispersed into
the gas as a spray, and the liquid droplets are the
main collectors for the solid particles.
• It consists of an open vessel with one or more sets of
spray nozzles to distribute the scrubbing liquid.
• Typically, the gas stream enters at the bottom and
passes upward through the sprays.
23. • Devices called wet scrubbers trap suspended
particles by direct contact with a spray of water
or other liquid.