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Complications
of
local
anesthesia
Presented by:-
Dr. Salabh Singh Parihar
What is “local anesthesia”?
Loss of sensation in a circumscribed area of the body caused by
depression of excitation in nerve endings or inhibition of the
conduction process in peripheral nerves.
Complication
“Any deviation from the normally expected pattern during or after the
securing regional analgesia.”
Classification
Primary or secondary
Mild or sever
Transient or permanent
Attributed to solution or needle insertion
TYPES OF LA
COMPLICATIONS
Local complication
Systemic complication
Needle breakage
Prolonged anesthesia or paresthesia
Facial nerve paralysis
Trismus
Soft tissue injury
Hematoma
Local Complications
Pain during injection
Infection
Edema
Sloughing of tissues
Post anesthetic intraoral lesions
Systemic complications
Toxicity
Idiosyncrasy
Allergy
Anaphylactic reactions
KEEP IN MIND
A - Airway - clear
adequate respiration
B - Bleeding - stopped
achieve inlet to vessels
C - Circulation - fluid if needed
D - Drugs to treat the present condition
TOXICITY
It refers to the symptoms manifested as a results of over dosage or
excessive administration of the solution.
Cause:
• Intravascular injection usually coupled with too rapid deposition of
solution
• Too large a volume
• Rapid absorption into bloodstream
Symptoms:(clinically)
Talkativeness, restlessness, apprehension, excitement, convulsions,
lethargy, sleepiness, unconsciousness
Increase or decrease in BP, pulse rate and respiration, nausea and vomiting is
also seen.
Prevention:
• Aspiration must be performed before injecting.
• Smallest possible volume of drugs should be used.
• A vasoconstrictor should be employed with the local anesthetic.
Treatment:-
Mild stimulation - no t/m
stop further injection
Moderate stimulation - I.V. inj. Of Barbiturates
0.2% solution of sodium thiopental
oxygen inhalation
Convulsions phase - anticonvulsant I.V./I.M.
coramine (150-450 mg I.V.), metrazol (100mg I.V.)
oxygen inhalation
Depression phase - artificial respiration
I.V. fluid
IDIOSYNCRASY
The term idiosyncrasy is defined as any reaction to a local anesthetic or drug
that cannot be classified as toxic or allergic.
Idiosyncrasy have no relation to the pharmacology of the drug and may vary
in degree from day, to day even in the same patient.
THE TREATMENT FOR IDIOSYNCRASY TYPE OF EMERGENCY:
The patients airway must be maintained and adequate oxygenation assured.
• Steps should be taken to evaluate the circulation and support it by positional
changes, drugs, or parenteral fluids.
• Precautions may also be exercised to protect the patient from injury to himself
as a result of convulsive seizures, loss of consciousness or similar reactions.
ALLERGY
• Allergy is a hypersensitive reaction that occurs through exposure to an antigen.
CAUSE:
The primary cause of allergic reactions is a specific antigen-antibody reaction
in a patient who has previously been sensitizing to a particular drug or chemical
derivative thereof.
ALLERGY
SYMPTOMS:
1.Rashes
2.Urticaria
3.Mucous membrane congestion
a. Rhinitis
b. Asthmatic symptoms
PREVENTION:
1. Adequate preanesthetic evaluation must be done.
2. No drug or drugs should be used if the patient gives a history of previous allergic
reactions to them.
ANAPHYLACTIC REACTIONS
Anaphylaxis is a severe form of allergic reactions occurs suddenly &
end fatally in which sudden violent loss of vasomotor tonus.
CLINICALLY
• Drop in B.P.
• Weak rapid pulse
• Death
MANAGEMENT
Benadryl 20 – 40 mg I.V. or I.M.
Epinephrine 1:1000 concentration
LOCAL REACTIONS
• Infection
• Tissue irritation
FAINTING OR SYNCOPE
It is due to temporary cerebral ischemia as a results of dilation of the
splanchnic B.P. & reduced cardiac output.
SIGN & SYMPTOMS
Pallor
Cold
sweating
nausea
Loss of consciousness
MANAGEMENT
• Stop dental procedure
• Place patients in supine position with slight head down or elevate the
legs to increase cerebral circulation.
or
• Place the hands of the patient behind his head and bend him forward
until his head is in b/w the knee to (produce pressure on the
splanchnic B.P. to replace the blood that drained from the head).
• Aromatic spirit (ammonia) held under the nose of the pt. for several
breath.
MUSCLE TRISMUS
Inability to open the mouth normally.
Etiology:
Injection in to muscles or ligaments
Needle borne infection
Contaminated / irritating solution
Hematoma formation in the muscle
MANAGEMENT
Depends upon the cause.
• It is due to trauma it slight muscle exercise & during therapy to
relieve pain if present.
• If due to infection this needs antibiotics.
Heat therapy
Warm saline rinses
Analgesics
Muscles relaxant
PAIN DURING INJECTION
Pain during or after the administration of a regional anesthetic is very
common.
ETIOLOGY:
Injection in to a muscle or ligament, parotid gland, TMJ
Using a non isotonic solution
Very cold solution
Management:
Assure the patients
Analgesics
Contaminated solution
Too rapid injection resulting in tissue distention
Numerous needle puncture
EDEMA
It is usually a symptom.
ETIOLOGY
• Trauma
• Allergy
• Infection
• hemorrhage
MANAGEMENT
• Trauma – resolve in few days without therapy
• Hemorrhage – resolve slowly 7-14 days
• Allergy – life threatening, airway impairment – basic life support,
call medical help, Epinephrine – 0.3mg, Antihistamine,
Corticosteroids
• Total airway obstruction – Tracheostomy
INFECTION
Contaminated non sterile needle or solution.
Carrying surface bacteria from non sterile mucous membrane in to the
deeper structures with the tip of the needle are the causative factors.
Injection in to infected area.
MANAGEMENT
Antibiotics
Anti inflammatory drugs
Use disposable syringe.
NEEDLE BROKEN
CAUSE:
• Unexpected movement – patient (if patient movement is opposite
to path of needle insertion)
• Multiple used needle
• Defective manufacture of needles
• smaller gauge – more likely to break
• On most occasious accidental breakage takes place at the hub.
• This enables the operator to remove the broken needle by grasping
the portion remaining in view.
MANAGEMENT
• Patient – not to move – hand in the mouth – mouth open
• Fragment visible – remove it
• Fragment not visible – inform patient – not necessary for
intervention immediately – Radiograph suggested
PROLONGED ANESTHESIA
ETIOLOGY:
contamination of the anesthetic solution with alcohol or
some other germicidal solution.
Needle trauma to nerve tissue.
Trauma & swelling of the soft tissue in proximity to the nerve.
MANAGEMENT
• Assure the patients.
• it takes some time to disappear.
HAEMATOMA & ECCHYMOSIS
“effusion of blood into extra-vascular spaces”
Causes
• Arterial & venous puncture – common in PSA & Inf. Alv. nerve blocks
• Patients with bleeding disorders
Problem
• Bruise – may / may not be visible extra-orally
• Complications – pain & trismus
• Swelling & discoloration
MANAGEMENT
• Knowledge of normal anatomy – proper technique
• Shorter needle – PSA, minimize the number of penetration
• Discard defective needles- barbed needles
• Ice pack
SLOUGHING & ULCERATION
Causes
• Epithelial desquamation – topical anaesthesia – long time,
heightened sensitivity to LA
• Sterile abscess – secondary to prolonged ischemia – VC in LA 
site – hard palate
Problems
• Pain & infection
MANAGEMENT
• Symptomatic – pain – analgesia
• Epithelial desquamation – resolve few days
• Sterile abscess resolve  7-10 days
SOFT TISSUE INJURY
Causes:
• Trauma occurs – frequently mentally / physically challenged children
• Primary cause – significantly longer duration of action
Problem:
• Pain & swelling
• Infection of soft tissue
Prevention:
• Cotton roll between lip & teeth
• Patient – guarded against eating / drinking
• Warning sticker
FACIAL NERVE PARALYSIS
Cause
• LA solution into parotid gland – usually while giving Inferior Alveoler Nr. Block,
Problem
• Ipsilateral loss of motor control – Buccinator muscle
• Inability to raise the corner of Mouth, close Eye lid
Prevention
• Needle tip to contact bone, redirection of needle to be done only after complete
withdrawal
MANAGEMENT
• Reassure the patient
• Resolves after action of LA is over
• Eye patches to the affected – eye drops
• Contact lenses if any – removed
POST ANESTHETIC INTRAORAL LESION
Ulcers are developed in the mouth after 2 days of intraoral LA
Cause
Trauma to the tissue by the needle, local aesthetic solutions cotton swab
or ay other instruments may activate the latent form of the disease like
herpes simplex, recurrent apthous stomatitis that was present in the tissues
before injection
Problems
Acute sensitivity in the ulcerated area
conclusion
The best way to avoid nearly all complications relating to
administration of local anesthetics is to use the right technique and to
have a good knowledge of the anatomy of the trigeminal nerve and the
adjacent anatomical structures.
However, if complications occur, the dentist should know how best to
manage them.
References
Local Anesthesia- Stanley Malamed.
Monheim’s Local Anesthesia And Pain Control In Dental Practice.
Complications of local anesthesia

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Complications of local anesthesia

  • 1.
  • 3. What is “local anesthesia”? Loss of sensation in a circumscribed area of the body caused by depression of excitation in nerve endings or inhibition of the conduction process in peripheral nerves.
  • 4. Complication “Any deviation from the normally expected pattern during or after the securing regional analgesia.”
  • 5. Classification Primary or secondary Mild or sever Transient or permanent Attributed to solution or needle insertion
  • 6. TYPES OF LA COMPLICATIONS Local complication Systemic complication
  • 7. Needle breakage Prolonged anesthesia or paresthesia Facial nerve paralysis Trismus Soft tissue injury Hematoma Local Complications
  • 8. Pain during injection Infection Edema Sloughing of tissues Post anesthetic intraoral lesions
  • 10. KEEP IN MIND A - Airway - clear adequate respiration B - Bleeding - stopped achieve inlet to vessels C - Circulation - fluid if needed D - Drugs to treat the present condition
  • 11. TOXICITY It refers to the symptoms manifested as a results of over dosage or excessive administration of the solution. Cause: • Intravascular injection usually coupled with too rapid deposition of solution • Too large a volume • Rapid absorption into bloodstream
  • 12. Symptoms:(clinically) Talkativeness, restlessness, apprehension, excitement, convulsions, lethargy, sleepiness, unconsciousness Increase or decrease in BP, pulse rate and respiration, nausea and vomiting is also seen. Prevention: • Aspiration must be performed before injecting. • Smallest possible volume of drugs should be used. • A vasoconstrictor should be employed with the local anesthetic.
  • 13. Treatment:- Mild stimulation - no t/m stop further injection Moderate stimulation - I.V. inj. Of Barbiturates 0.2% solution of sodium thiopental oxygen inhalation Convulsions phase - anticonvulsant I.V./I.M. coramine (150-450 mg I.V.), metrazol (100mg I.V.) oxygen inhalation Depression phase - artificial respiration I.V. fluid
  • 14. IDIOSYNCRASY The term idiosyncrasy is defined as any reaction to a local anesthetic or drug that cannot be classified as toxic or allergic. Idiosyncrasy have no relation to the pharmacology of the drug and may vary in degree from day, to day even in the same patient.
  • 15. THE TREATMENT FOR IDIOSYNCRASY TYPE OF EMERGENCY: The patients airway must be maintained and adequate oxygenation assured. • Steps should be taken to evaluate the circulation and support it by positional changes, drugs, or parenteral fluids. • Precautions may also be exercised to protect the patient from injury to himself as a result of convulsive seizures, loss of consciousness or similar reactions.
  • 16. ALLERGY • Allergy is a hypersensitive reaction that occurs through exposure to an antigen. CAUSE: The primary cause of allergic reactions is a specific antigen-antibody reaction in a patient who has previously been sensitizing to a particular drug or chemical derivative thereof.
  • 17. ALLERGY SYMPTOMS: 1.Rashes 2.Urticaria 3.Mucous membrane congestion a. Rhinitis b. Asthmatic symptoms PREVENTION: 1. Adequate preanesthetic evaluation must be done. 2. No drug or drugs should be used if the patient gives a history of previous allergic reactions to them.
  • 18. ANAPHYLACTIC REACTIONS Anaphylaxis is a severe form of allergic reactions occurs suddenly & end fatally in which sudden violent loss of vasomotor tonus.
  • 19. CLINICALLY • Drop in B.P. • Weak rapid pulse • Death MANAGEMENT Benadryl 20 – 40 mg I.V. or I.M. Epinephrine 1:1000 concentration
  • 21. FAINTING OR SYNCOPE It is due to temporary cerebral ischemia as a results of dilation of the splanchnic B.P. & reduced cardiac output. SIGN & SYMPTOMS Pallor Cold sweating nausea Loss of consciousness
  • 22. MANAGEMENT • Stop dental procedure • Place patients in supine position with slight head down or elevate the legs to increase cerebral circulation. or • Place the hands of the patient behind his head and bend him forward until his head is in b/w the knee to (produce pressure on the splanchnic B.P. to replace the blood that drained from the head). • Aromatic spirit (ammonia) held under the nose of the pt. for several breath.
  • 23. MUSCLE TRISMUS Inability to open the mouth normally. Etiology: Injection in to muscles or ligaments Needle borne infection Contaminated / irritating solution Hematoma formation in the muscle
  • 24. MANAGEMENT Depends upon the cause. • It is due to trauma it slight muscle exercise & during therapy to relieve pain if present. • If due to infection this needs antibiotics. Heat therapy Warm saline rinses Analgesics Muscles relaxant
  • 25. PAIN DURING INJECTION Pain during or after the administration of a regional anesthetic is very common. ETIOLOGY: Injection in to a muscle or ligament, parotid gland, TMJ Using a non isotonic solution Very cold solution
  • 26. Management: Assure the patients Analgesics Contaminated solution Too rapid injection resulting in tissue distention Numerous needle puncture
  • 27. EDEMA It is usually a symptom. ETIOLOGY • Trauma • Allergy • Infection • hemorrhage
  • 28. MANAGEMENT • Trauma – resolve in few days without therapy • Hemorrhage – resolve slowly 7-14 days • Allergy – life threatening, airway impairment – basic life support, call medical help, Epinephrine – 0.3mg, Antihistamine, Corticosteroids • Total airway obstruction – Tracheostomy
  • 29. INFECTION Contaminated non sterile needle or solution. Carrying surface bacteria from non sterile mucous membrane in to the deeper structures with the tip of the needle are the causative factors. Injection in to infected area.
  • 31. NEEDLE BROKEN CAUSE: • Unexpected movement – patient (if patient movement is opposite to path of needle insertion) • Multiple used needle • Defective manufacture of needles • smaller gauge – more likely to break
  • 32. • On most occasious accidental breakage takes place at the hub. • This enables the operator to remove the broken needle by grasping the portion remaining in view. MANAGEMENT • Patient – not to move – hand in the mouth – mouth open • Fragment visible – remove it • Fragment not visible – inform patient – not necessary for intervention immediately – Radiograph suggested
  • 33. PROLONGED ANESTHESIA ETIOLOGY: contamination of the anesthetic solution with alcohol or some other germicidal solution. Needle trauma to nerve tissue. Trauma & swelling of the soft tissue in proximity to the nerve.
  • 34. MANAGEMENT • Assure the patients. • it takes some time to disappear.
  • 35. HAEMATOMA & ECCHYMOSIS “effusion of blood into extra-vascular spaces” Causes • Arterial & venous puncture – common in PSA & Inf. Alv. nerve blocks • Patients with bleeding disorders Problem • Bruise – may / may not be visible extra-orally • Complications – pain & trismus • Swelling & discoloration
  • 36. MANAGEMENT • Knowledge of normal anatomy – proper technique • Shorter needle – PSA, minimize the number of penetration • Discard defective needles- barbed needles • Ice pack
  • 37. SLOUGHING & ULCERATION Causes • Epithelial desquamation – topical anaesthesia – long time, heightened sensitivity to LA • Sterile abscess – secondary to prolonged ischemia – VC in LA  site – hard palate Problems • Pain & infection
  • 38. MANAGEMENT • Symptomatic – pain – analgesia • Epithelial desquamation – resolve few days • Sterile abscess resolve  7-10 days
  • 39. SOFT TISSUE INJURY Causes: • Trauma occurs – frequently mentally / physically challenged children • Primary cause – significantly longer duration of action Problem: • Pain & swelling • Infection of soft tissue Prevention: • Cotton roll between lip & teeth • Patient – guarded against eating / drinking • Warning sticker
  • 40. FACIAL NERVE PARALYSIS Cause • LA solution into parotid gland – usually while giving Inferior Alveoler Nr. Block, Problem • Ipsilateral loss of motor control – Buccinator muscle • Inability to raise the corner of Mouth, close Eye lid Prevention • Needle tip to contact bone, redirection of needle to be done only after complete withdrawal
  • 41. MANAGEMENT • Reassure the patient • Resolves after action of LA is over • Eye patches to the affected – eye drops • Contact lenses if any – removed
  • 42. POST ANESTHETIC INTRAORAL LESION Ulcers are developed in the mouth after 2 days of intraoral LA Cause Trauma to the tissue by the needle, local aesthetic solutions cotton swab or ay other instruments may activate the latent form of the disease like herpes simplex, recurrent apthous stomatitis that was present in the tissues before injection Problems Acute sensitivity in the ulcerated area
  • 43. conclusion The best way to avoid nearly all complications relating to administration of local anesthetics is to use the right technique and to have a good knowledge of the anatomy of the trigeminal nerve and the adjacent anatomical structures. However, if complications occur, the dentist should know how best to manage them.
  • 44. References Local Anesthesia- Stanley Malamed. Monheim’s Local Anesthesia And Pain Control In Dental Practice.

Editor's Notes

  1. 1Cerebral cortex.2 medula