Cold creams –
formulation and
evaluation
preparedby :Nidhijoshi
b-pharmSem-6
smtrdgardicollege
Guidedby : assi.ms. kajal pradhan
CONTENTS
 What is cold cream
 Ideal characteristics
 Formula/ingredients
 Preparation
 Evaluation
 Uses
 Best marketed products
 Important questions
 References
These type of emulsion are
water in oil type of
emulsion.
• What is cold cream?
They produce cooling sensation
by Evaporation of water after
application Of cream to the
skin. hence, they are known as
cold cream
Also called moisturizer or
moisturizing cream.
Please add pictures
It should provide a smooth texture.
It should not be sticky or dirty. Should
not cause skin irritation.
• Ideal characteristics
It should look elegant and
Do not dry
The sensitization index should be low.
Must be miscible with skin secretions
Methyl/propyl p-
hydroxybenzoate
preservative
Water, rose water,
Vehicle
Glycerin , glycerol
Humectants
Sodium borate, borax
emulsifier
Almond oil , mineral oil,
Isopropyl myristate,
petroleum jelly
emollient
Cetyl esters wax, white
bees wax, spermaceti,
Stiffening
agent
• Common ingredients
• Formula as per BP
Name of Raw
materials
Quantity Function
Almond oil 610.00 ml
Emollient, Solvent and vehicles of an
oil phase
White beeswax 180.00 g Stiffening agent
Borax 10.00 g Emulsifying agent
Rosewater 199.00 ml
Vehicle and Solvent of an aqueous
phase
Oil of rose 1.00 ml Flavoring agent
Melt
beeswax
about
70c
Add
mineral in
melted
beeswax (A)
Dissolve
borax in
water(B)
Add
mixture b
in a with
stirring
Semisolid
mass
formed
• preparation method
First
marketed
cold cream
Colour, odour ,appearance
Extent of area to which the
topical application spreads
Determine by Brookfield viscometer
Spindle no.64
Redness, edema,
inflammation
Organoleptic
property
Spread
ability
viscosity
irritancy
homogeneity
Observe by visual
appearance or by touchhere
• Evaluation test(cream)
1.Dilution test
2.Microbial
growth
3.Patch test
4.Dye test
Please add
pictures
Please replace the
text content and copy
your content here
Please replace the
text content and copy
your content here
Project A
Please replace the
text content and copy
your content here
Please replace the
text content and copy
your content here
Project B
• Evaluation test(emulsion)
1 2
3 4
• Please
add
pictures
• Uses
• Remove oil
soluble
impurities
from skin
• Emollient effect
and soothing
effect
• Best marketed products
Add
Titl
e
Add
Titl
e
Add
Titl
e
Add
Tit
le
• Gtu important questions
1.Define cream write the formulation of foundation
cream
2. Formulation and preparation of moisturizing cream
3. Write the principle involved in the formation of
creams. Discuss various alkalies used in cream
formulation
4. write a formula of cold cream
• References
a. The United States pharmacopeia The National formulary. Rockville, Md.: United
States Pharmacopeial Convention, Inc. (USP 21 – NF 16). Lachman, Lieberman,
H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Lea and
Fibiger, New York, 15th edition; 2013
b. Remington, Joseph P, and Paul Beringer. Remington: The Science and Practice of
Pharmacy. 21st edition. Philadelphia: Lippincott Williams & Wilkins; 2005.
c. Poucher, W A, and George M. Howard. Perfumes, Cosmetics, and Soaps. London:
Chapman and Hall, 1974.
d. Chauhan lalita, gupta sahani Creams: a review on classification ,preparation
method ,journal of drug delivery and therapeutics,2020:281-289
T H A N K S

Cold cream.pptx

  • 1.
    Cold creams – formulationand evaluation preparedby :Nidhijoshi b-pharmSem-6 smtrdgardicollege Guidedby : assi.ms. kajal pradhan
  • 2.
    CONTENTS  What iscold cream  Ideal characteristics  Formula/ingredients  Preparation  Evaluation  Uses  Best marketed products  Important questions  References
  • 3.
    These type ofemulsion are water in oil type of emulsion. • What is cold cream? They produce cooling sensation by Evaporation of water after application Of cream to the skin. hence, they are known as cold cream Also called moisturizer or moisturizing cream. Please add pictures
  • 4.
    It should providea smooth texture. It should not be sticky or dirty. Should not cause skin irritation. • Ideal characteristics It should look elegant and Do not dry The sensitization index should be low. Must be miscible with skin secretions
  • 5.
    Methyl/propyl p- hydroxybenzoate preservative Water, rosewater, Vehicle Glycerin , glycerol Humectants Sodium borate, borax emulsifier Almond oil , mineral oil, Isopropyl myristate, petroleum jelly emollient Cetyl esters wax, white bees wax, spermaceti, Stiffening agent • Common ingredients
  • 6.
    • Formula asper BP Name of Raw materials Quantity Function Almond oil 610.00 ml Emollient, Solvent and vehicles of an oil phase White beeswax 180.00 g Stiffening agent Borax 10.00 g Emulsifying agent Rosewater 199.00 ml Vehicle and Solvent of an aqueous phase Oil of rose 1.00 ml Flavoring agent
  • 7.
    Melt beeswax about 70c Add mineral in melted beeswax (A) Dissolve boraxin water(B) Add mixture b in a with stirring Semisolid mass formed • preparation method First marketed cold cream
  • 8.
    Colour, odour ,appearance Extentof area to which the topical application spreads Determine by Brookfield viscometer Spindle no.64 Redness, edema, inflammation Organoleptic property Spread ability viscosity irritancy homogeneity Observe by visual appearance or by touchhere • Evaluation test(cream)
  • 9.
    1.Dilution test 2.Microbial growth 3.Patch test 4.Dyetest Please add pictures Please replace the text content and copy your content here Please replace the text content and copy your content here Project A Please replace the text content and copy your content here Please replace the text content and copy your content here Project B • Evaluation test(emulsion) 1 2 3 4
  • 10.
    • Please add pictures • Uses •Remove oil soluble impurities from skin • Emollient effect and soothing effect
  • 11.
  • 12.
    Add Titl e Add Titl e Add Titl e Add Tit le • Gtu importantquestions 1.Define cream write the formulation of foundation cream 2. Formulation and preparation of moisturizing cream 3. Write the principle involved in the formation of creams. Discuss various alkalies used in cream formulation 4. write a formula of cold cream
  • 13.
    • References a. TheUnited States pharmacopeia The National formulary. Rockville, Md.: United States Pharmacopeial Convention, Inc. (USP 21 – NF 16). Lachman, Lieberman, H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Lea and Fibiger, New York, 15th edition; 2013 b. Remington, Joseph P, and Paul Beringer. Remington: The Science and Practice of Pharmacy. 21st edition. Philadelphia: Lippincott Williams & Wilkins; 2005. c. Poucher, W A, and George M. Howard. Perfumes, Cosmetics, and Soaps. London: Chapman and Hall, 1974. d. Chauhan lalita, gupta sahani Creams: a review on classification ,preparation method ,journal of drug delivery and therapeutics,2020:281-289
  • 14.
    T H AN K S