This document summarizes a presentation about CloudMan, a platform for deploying cloud computing resources and Galaxy instances. CloudMan allows users to setup cloud clusters in minutes without expertise, provides over 700GB of reference genomes and bioinformatics tools, and enables customization and sharing of derived cluster instances. It bridges users, isolated Galaxy instances, and cloud infrastructure. Key features include deployment on AWS, automated configuration, dynamic storage, and elastic scaling of resources.

1. C A M P A I G N
Chief Development Officer
Emory University
C A M P A I G N
School of Nursing Development
Emory University
1520 Clifton Road, NE
School of Nursing Development
Atlanta, Georgia 30322-4207
1520 Clifton Road, NE
P 404.727.1234
Atlanta, Georgia 30322-4207
E adorrill@emory.edu
Discovery of human heteroplasmic sites P 404.727.1234
Enabling of human heteroplasmic sites
enabled NGS analysis with(out)
E adorrill@emory.edu
Discovery by an accessible interface to
cloud computing infrastructure to
enabled by infrastructure
the an accessible interface
cloud computing infrastructure
Enis Afgan, the Galaxy Team,Francesca Chiaromonte
Enis Afgan, Hiroki Goto, Ian Paul,
Anton Nekrutenko,
James Taylor
Kateryna Makova, Anton Nekrutenko, James Taylor
Enis Afgan, Hiroki Goto, Ian Paul, Francesca Chiaromonte
Kateryna Makova, Anton Nekrutenko, James Taylor
Bioinformatics Open Source Conference, July 16, 2011, Vienna
missions: you are free to blog or live-blog about this presentation as long as you attribute the work to its au

2. CloudMan-as-a-Bridge
A. Users in different labs B. Isolated Galaxy instance(s) C. Dense data center

3. CloudMan-as-a-Bridge
A. Users in different labs B. Isolated Galaxy instance(s) C. Dense data center
SaaS

4. CloudMan-as-a-Bridge
A. Users in different labs B. Isolated Galaxy instance(s) C. Dense data center
SaaS IaaS

5. CloudMan-as-a-Bridge
A. Users in different labs B. Isolated Galaxy instance(s) C. Dense data center
SaaS CloudMan + Galaxy IaaS

6. CloudMan Platform
A complete solution for instantiating and
managing cloud resources
With automatically configured Galaxy (if desired)
Scope of tools and reference datasets exceed Galaxy Main
Deploy a (Galaxy) cluster in minutes!

7. CloudMan features
• Deployment on Amazon Web Services Cloud
• Wizard-guided setup: requires no computational expertise, no
infrastructure, no software
• Automated (thus reproducible) configuration for machine image, tools,
and data
• Four modes of cluster type setup
• Dynamic persistent storage
• Elastic resource scaling: manual or automatic based on workload
• Standalone deployment, requiring no external dependencies or services
• Customizable by individual users
• Sharing of derived cluster instances -> even the customized ones!

8. CloudMan features
• Deployment on Amazon Web Services Cloud
• Wizard-guided setup: requires no computational expertise, no
infrastructure, no software
• Automated (thus reproducible) configuration for machine image, tools,
and data
• Four modes of cluster type setup
• Dynamic persistent storage
• Elastic resource scaling: manual or automatic based on workload
• Standalone deployment, requiring no external dependencies or services
• Customizable by individual users
• Sharing of derived cluster instances -> even the customized ones!

9. Deploying a cluster on AWS
1.

10. Deploying a cluster on AWS
1.
2.

11. Deploying a cluster on AWS
1.
2.
3.

12. Deploying a cluster on AWS
1.
2.
3.
4.

13. CloudBioLinux + Galaxy
+ CloudMan =
• A lot of (NGS) tools immediately available
and easily accessible
• 700GB of reference genome data
Bowtie, BWA, Samtools, MAQ, BFAST, ABySS, Velvet,
MACS, Tophat, Cufflinks, MegaBLAST, BLAST, Sputnik,
Taxonomy, HyPhy, Lastz, Perm, GATK, Srma, Beam, Pass,
LPS, Plink, Haploview, Freebayes, Mosaik, Picard, ...

14. But what if your tool
(or data) is missing?
1. Add it! (via automation)
- CloudMan instances
are self-contained
2. Save & share Add tools
- With individual users
or make it public
Add data

15. Deployment sharing

16. Deployment sharing

17. Deployment sharing

18. Use CloudMan as SaaS
Use CloudMan as PaaS
It’s automated, reproducible, extensible, and
transparent.

19. Enis Afgan Dannon Baker Dan Blankenberg Nate Coraor
Dave Clements Jeremy Goecks Jennifer Jackson Greg von Kuster
Kanwei Li James Taylor Kelly Vincent Anton Nekrutenko
Supported by the NHGRI (HG005542, HG004909, HG005133), NSF (DBI-0850103), Penn State University,
Emory University, and the Pennsylvania Department of Public Health