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Clinical Neuroanatomy
language function
95% in left hemisphere
Broca's area
injury causes inability to speak
Wernick's area (superior temporal lobe)
injury causes inability to comprehend
upper motor neuron
injury
distal muscles are weaker
than the proximal muscles
extensors muscles are weaker
than the flexors muscles
pre-central gyrus
primary motor cortex
corticospinal tract
sends axons through posterior limb of internal capsule
injury here involves
face, arm and leg (just
like a lesion of the
whole precentral gyrus)
goes through the brainstem
cross at pyramidal decussation
(right before spinal cord)
goes through spinal cord
synapses with lower motor neuron
post-central gyrus
primary sensory cortex
2 parallel systems mediation sensation from the body
thalamus injury involves
both systems, just like
a lesion of the whole
postcentral gyrus
posterior or dorsal column pathway vibration and proprioception
1st neuron goes through spinal cord and synapses in the brain stem
2nd neuron crosses and goes to the
thalamus where it synapses again
3rd neuron projects to postcentral gyrus
spinotalhamic pathway temperature and pain
1st neuron immediately synapse at spinal cord
2nd neuron crosses at spinal cord and ascends up
the brain stem to the thalamaus where it synapses
3rd neuron projects to the postcentral cortex
primary visual cortex
right occipital lobe see the
left side of the world and vice-versa
sends optic radiations to the eyeballs
ocular motor neurons
left hemisphere starts drives the
eyes to the right and vice-versa
this is acomplished by frontal
eye fields (distinct areas of brain)
injury causes deviations to
the side of the lesion
vascular supply to the brain
2 carotid arteries
supplies the interior
2/3 of the brain
2 vertebral arteries
supplies the posterior
portion of the brain

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Clinical neuroanatomy

  • 1. Clinical Neuroanatomy language function 95% in left hemisphere Broca's area injury causes inability to speak Wernick's area (superior temporal lobe) injury causes inability to comprehend upper motor neuron injury distal muscles are weaker than the proximal muscles extensors muscles are weaker than the flexors muscles pre-central gyrus primary motor cortex corticospinal tract sends axons through posterior limb of internal capsule injury here involves face, arm and leg (just like a lesion of the whole precentral gyrus) goes through the brainstem cross at pyramidal decussation (right before spinal cord) goes through spinal cord synapses with lower motor neuron post-central gyrus primary sensory cortex 2 parallel systems mediation sensation from the body thalamus injury involves both systems, just like a lesion of the whole postcentral gyrus posterior or dorsal column pathway vibration and proprioception 1st neuron goes through spinal cord and synapses in the brain stem 2nd neuron crosses and goes to the thalamus where it synapses again 3rd neuron projects to postcentral gyrus spinotalhamic pathway temperature and pain 1st neuron immediately synapse at spinal cord 2nd neuron crosses at spinal cord and ascends up the brain stem to the thalamaus where it synapses 3rd neuron projects to the postcentral cortex primary visual cortex right occipital lobe see the left side of the world and vice-versa sends optic radiations to the eyeballs ocular motor neurons left hemisphere starts drives the eyes to the right and vice-versa this is acomplished by frontal eye fields (distinct areas of brain) injury causes deviations to the side of the lesion vascular supply to the brain 2 carotid arteries supplies the interior 2/3 of the brain 2 vertebral arteries supplies the posterior portion of the brain