SlideShare a Scribd company logo
 A 70-Year-old man is seen in follow-up at your
office after he has been hospitalized for a
myocardial infarction. He underwent successful
angioplasty and is currently asymptomatic. Prior to
his MI, he was not on medications. He is not a
smoker and is not diabetic. During his
hospitalization, he was noted to have persistently
elevated blood pressure readings. He had asthma as
a child, but has not had any recent wheezing
episodes . While in the hospital, he was started on
oral metoprolol.
Questions
1. Metoprolol is selective for which adrenoceptor?
2. What effects do agents such as metoprolol have
on the cardiovascular system?
3. In which organ is metoprolol primarily
metabolized?
4. Why must beta adrenergic antagonists be used
with caution in asthmatics?
Summary
 A 70-year-old hypertensive man with a
childhood history of asthma had a recent
myocardial infarction and is prescribed
metoprolol
Adrenoceptor selectively
antagonized by metaprolol
Beta 1
Effect of beta adrenoceptor antagonists
on the cardiovascular system
 Reduction of sympathetic-stimulated increases
in heart rate, contractility and cardiac output
 Lower BP as a result of effects on heart, renin-
angiotensin system, and CNS
 Increased atrioventricular (AV) conduction
time and refractoriness.
Organ in which metoprolol is
metabolized
Liver
Reason for caution in use in
asthhmatics
 Blockade of beta 2 adrenoceptor in bronchial
smooth muscle may cause increased airway
resistance and bronchospasm

More Related Content

What's hot

Clinical Case 2
Clinical Case 2Clinical Case 2
Clinical Case 2
Venkata Subba Reddy
 
Cardiovascular pharmacology
Cardiovascular pharmacologyCardiovascular pharmacology
Cardiovascular pharmacology
Reza Heidari
 
Nonsteroidal anti inflammatory drugs (NSAIDS)
Nonsteroidal anti inflammatory drugs (NSAIDS)Nonsteroidal anti inflammatory drugs (NSAIDS)
Nonsteroidal anti inflammatory drugs (NSAIDS)
abdul waheed
 
Local anaesthetics
Local anaestheticsLocal anaesthetics
Local anaesthetics
OPTOM FASLU MUHAMMED
 
Corticosteroids
CorticosteroidsCorticosteroids
Corticosteroids
Dr Pralhad Patki
 
Adrenergic receptors
Adrenergic receptorsAdrenergic receptors
Adrenergic receptors
Amy Mehaboob
 
Mechanism of local anesthesia
Mechanism of local anesthesiaMechanism of local anesthesia
Mechanism of local anesthesia
ishita1994
 
Factors modifying drug actionsvpp
Factors modifying drug actionsvppFactors modifying drug actionsvpp
Factors modifying drug actionsvpp
Virupanagouda patil
 
Pharmacodynamics revised
Pharmacodynamics   revisedPharmacodynamics   revised
Pharmacodynamics revised
Omar Moatamed
 
Local anesthetic solution
Local anesthetic solutionLocal anesthetic solution
Local anesthetic solution
Saeed Bajafar
 
Pharmacology of corticosteroids
Pharmacology of corticosteroidsPharmacology of corticosteroids
Pharmacology of corticosteroids
Mayur Chaudhari
 
Adrenergic drugs.
Adrenergic drugs.Adrenergic drugs.
Adrenergic drugs.
Md kawsar
 
Beta blockers
Beta blockersBeta blockers
Beta blockers
Naser Tadvi
 
Role of fluoride in dental health
Role of fluoride in dental healthRole of fluoride in dental health
Role of fluoride in dental health
Sarang Suresh Hotchandani
 
Vasodilators - Medicinal chemistry for B.Pharm.
Vasodilators - Medicinal chemistry for B.Pharm.Vasodilators - Medicinal chemistry for B.Pharm.
Vasodilators - Medicinal chemistry for B.Pharm.
Purna Nagasree K
 
Corticosteroid
CorticosteroidCorticosteroid
Corticosteroid
Joel D'silva
 
3. Drugs acting on bones
3. Drugs acting on bones3. Drugs acting on bones
3. Drugs acting on bones
Mirza Anwar Baig
 
Haematinics
HaematinicsHaematinics
Limit test of Arsenic
Limit test of ArsenicLimit test of Arsenic
Limit test of Arsenic
Sonali Pawar
 
Ganglionic stimulants and blockers suffi
Ganglionic stimulants and blockers suffiGanglionic stimulants and blockers suffi
Ganglionic stimulants and blockers suffi
Dr.UMER SUFYAN M
 

What's hot (20)

Clinical Case 2
Clinical Case 2Clinical Case 2
Clinical Case 2
 
Cardiovascular pharmacology
Cardiovascular pharmacologyCardiovascular pharmacology
Cardiovascular pharmacology
 
Nonsteroidal anti inflammatory drugs (NSAIDS)
Nonsteroidal anti inflammatory drugs (NSAIDS)Nonsteroidal anti inflammatory drugs (NSAIDS)
Nonsteroidal anti inflammatory drugs (NSAIDS)
 
Local anaesthetics
Local anaestheticsLocal anaesthetics
Local anaesthetics
 
Corticosteroids
CorticosteroidsCorticosteroids
Corticosteroids
 
Adrenergic receptors
Adrenergic receptorsAdrenergic receptors
Adrenergic receptors
 
Mechanism of local anesthesia
Mechanism of local anesthesiaMechanism of local anesthesia
Mechanism of local anesthesia
 
Factors modifying drug actionsvpp
Factors modifying drug actionsvppFactors modifying drug actionsvpp
Factors modifying drug actionsvpp
 
Pharmacodynamics revised
Pharmacodynamics   revisedPharmacodynamics   revised
Pharmacodynamics revised
 
Local anesthetic solution
Local anesthetic solutionLocal anesthetic solution
Local anesthetic solution
 
Pharmacology of corticosteroids
Pharmacology of corticosteroidsPharmacology of corticosteroids
Pharmacology of corticosteroids
 
Adrenergic drugs.
Adrenergic drugs.Adrenergic drugs.
Adrenergic drugs.
 
Beta blockers
Beta blockersBeta blockers
Beta blockers
 
Role of fluoride in dental health
Role of fluoride in dental healthRole of fluoride in dental health
Role of fluoride in dental health
 
Vasodilators - Medicinal chemistry for B.Pharm.
Vasodilators - Medicinal chemistry for B.Pharm.Vasodilators - Medicinal chemistry for B.Pharm.
Vasodilators - Medicinal chemistry for B.Pharm.
 
Corticosteroid
CorticosteroidCorticosteroid
Corticosteroid
 
3. Drugs acting on bones
3. Drugs acting on bones3. Drugs acting on bones
3. Drugs acting on bones
 
Haematinics
HaematinicsHaematinics
Haematinics
 
Limit test of Arsenic
Limit test of ArsenicLimit test of Arsenic
Limit test of Arsenic
 
Ganglionic stimulants and blockers suffi
Ganglionic stimulants and blockers suffiGanglionic stimulants and blockers suffi
Ganglionic stimulants and blockers suffi
 

Viewers also liked

ECONS REPORT
ECONS REPORTECONS REPORT
ECONS REPORT
Lillian June
 
ACC REPORT
ACC REPORTACC REPORT
ACC REPORT
Lillian June
 
National geographic
National geographicNational geographic
National geographic
Mihail_Sirmanov
 
Kauri Cliffs Golf Course Yardage Chart
Kauri Cliffs Golf Course Yardage Chart Kauri Cliffs Golf Course Yardage Chart
Kauri Cliffs Golf Course Yardage Chart
Paul Thornton
 
Developing an argumentative essay introduction
Developing an argumentative essay introductionDeveloping an argumentative essay introduction
Developing an argumentative essay introduction
raynerhd
 
Mastic Surface Treatment Applicator
Mastic Surface Treatment ApplicatorMastic Surface Treatment Applicator
Mastic Surface Treatment Applicator
Crystal Lance
 
Handleiding online boeken in alle veiligheid
Handleiding online boeken in alle veiligheidHandleiding online boeken in alle veiligheid
Handleiding online boeken in alle veiligheid
Luc De Smedt
 
Apple x fbi o que está acontecendo-
Apple x fbi   o que está acontecendo-Apple x fbi   o que está acontecendo-
Apple x fbi o que está acontecendo-
Thiago Escobar
 
engineering-africa
engineering-africaengineering-africa
engineering-africa
Filipe de Gouveia
 
Bat kid
Bat kidBat kid
Bat kid
119604
 
Cruise Allure of the Seas Algemene Informatie
Cruise Allure of the Seas   Algemene InformatieCruise Allure of the Seas   Algemene Informatie
Cruise Allure of the Seas Algemene Informatie
Luc De Smedt
 
Herramientas tic
Herramientas ticHerramientas tic
Herramientas tic
sulmasm24
 
CiviCRM 5.0 for Non-Techies
CiviCRM 5.0 for Non-TechiesCiviCRM 5.0 for Non-Techies
CiviCRM 5.0 for Non-Techies
tonymazz
 
MATHS REPORT
MATHS REPORTMATHS REPORT
MATHS REPORT
Lillian June
 
PSYCHO VIDEO REPORT
PSYCHO VIDEO REPORTPSYCHO VIDEO REPORT
PSYCHO VIDEO REPORT
Lillian June
 
Wynn energy resources and agriculture
Wynn energy resources  and agricultureWynn energy resources  and agriculture
Wynn energy resources and agriculture
Peter Wynn
 

Viewers also liked (18)

ECONS REPORT
ECONS REPORTECONS REPORT
ECONS REPORT
 
ACC REPORT
ACC REPORTACC REPORT
ACC REPORT
 
National geographic
National geographicNational geographic
National geographic
 
Kauri Cliffs Golf Course Yardage Chart
Kauri Cliffs Golf Course Yardage Chart Kauri Cliffs Golf Course Yardage Chart
Kauri Cliffs Golf Course Yardage Chart
 
Developing an argumentative essay introduction
Developing an argumentative essay introductionDeveloping an argumentative essay introduction
Developing an argumentative essay introduction
 
Mastic Surface Treatment Applicator
Mastic Surface Treatment ApplicatorMastic Surface Treatment Applicator
Mastic Surface Treatment Applicator
 
ARIF BUDIMAN
ARIF BUDIMANARIF BUDIMAN
ARIF BUDIMAN
 
Handleiding online boeken in alle veiligheid
Handleiding online boeken in alle veiligheidHandleiding online boeken in alle veiligheid
Handleiding online boeken in alle veiligheid
 
Apple x fbi o que está acontecendo-
Apple x fbi   o que está acontecendo-Apple x fbi   o que está acontecendo-
Apple x fbi o que está acontecendo-
 
engineering-africa
engineering-africaengineering-africa
engineering-africa
 
Bat kid
Bat kidBat kid
Bat kid
 
Cruise Allure of the Seas Algemene Informatie
Cruise Allure of the Seas   Algemene InformatieCruise Allure of the Seas   Algemene Informatie
Cruise Allure of the Seas Algemene Informatie
 
Foto fenomenální ,h1
Foto fenomenální  ,h1Foto fenomenální  ,h1
Foto fenomenální ,h1
 
Herramientas tic
Herramientas ticHerramientas tic
Herramientas tic
 
CiviCRM 5.0 for Non-Techies
CiviCRM 5.0 for Non-TechiesCiviCRM 5.0 for Non-Techies
CiviCRM 5.0 for Non-Techies
 
MATHS REPORT
MATHS REPORTMATHS REPORT
MATHS REPORT
 
PSYCHO VIDEO REPORT
PSYCHO VIDEO REPORTPSYCHO VIDEO REPORT
PSYCHO VIDEO REPORT
 
Wynn energy resources and agriculture
Wynn energy resources  and agricultureWynn energy resources  and agriculture
Wynn energy resources and agriculture
 

Similar to Clinical Case 6

Metoprolol Succinate: Uses, Dosage , Side effects.
Metoprolol Succinate: Uses, Dosage , Side effects.Metoprolol Succinate: Uses, Dosage , Side effects.
Metoprolol Succinate: Uses, Dosage , Side effects.
Medical Dialogues
 
antihypertensive_agent
antihypertensive_agentantihypertensive_agent
antihypertensive_agent
royal medical services
 
Cardiovascular Drugs-Medicinal Chemistry MANIK
Cardiovascular Drugs-Medicinal Chemistry MANIKCardiovascular Drugs-Medicinal Chemistry MANIK
Cardiovascular Drugs-Medicinal Chemistry MANIK
Imran Nur Manik
 
Metoprolol (ellen soyombo) final
Metoprolol (ellen soyombo) finalMetoprolol (ellen soyombo) final
Metoprolol (ellen soyombo) final
esoyombo
 
From eye drops to icu, a case report of three side effects of ophthalmic timo...
From eye drops to icu, a case report of three side effects of ophthalmic timo...From eye drops to icu, a case report of three side effects of ophthalmic timo...
From eye drops to icu, a case report of three side effects of ophthalmic timo...
Muhammad Asim Rana
 
CVS-_Antihypertensives-_Beta_blockers.pdf
CVS-_Antihypertensives-_Beta_blockers.pdfCVS-_Antihypertensives-_Beta_blockers.pdf
CVS-_Antihypertensives-_Beta_blockers.pdf
SanjayaManiDixit
 
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
PrasannRoy2
 
Pharmaceutical care plan
Pharmaceutical care planPharmaceutical care plan
Pharmaceutical care plan
Norliza Ariffin
 
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
Dr Hitesh Motwani
 
Hypertension - Role of Azilsartan ( Case based & Evidence based)
Hypertension  - Role of Azilsartan ( Case based & Evidence based)Hypertension  - Role of Azilsartan ( Case based & Evidence based)
Hypertension - Role of Azilsartan ( Case based & Evidence based)
PROFESSOR DR. MD. TOUFIQUR RAHMAN
 
Anti htn drugs
Anti htn drugsAnti htn drugs
Anti htn drugs
DrVishal Kandhway
 
Antiarrhythmic taste smell disturbances 1
Antiarrhythmic taste smell disturbances 1Antiarrhythmic taste smell disturbances 1
Antiarrhythmic taste smell disturbances 1
KshitijMankar
 
Bronchoconstrictor Drugs
Bronchoconstrictor Drugs Bronchoconstrictor Drugs
Bronchoconstrictor Drugs
Arsi University, Asella, Ethiopia
 
Beta blocker dr. kiran..
Beta blocker dr. kiran..Beta blocker dr. kiran..
Beta blocker dr. kiran..
Kiran Piparva
 
7.c v s
7.c v s 7.c v s
7.c v s
Lama K Banna
 
7.cvs
7.cvs7.cvs
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
Sujit Karpe
 
ECT .pptx
ECT .pptxECT .pptx
ECT .pptx
Sakun Rasaily
 
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docxASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
galerussel59292
 
Beta adrenergic blockers
Beta adrenergic blockersBeta adrenergic blockers
Beta adrenergic blockers
MuniSahu
 

Similar to Clinical Case 6 (20)

Metoprolol Succinate: Uses, Dosage , Side effects.
Metoprolol Succinate: Uses, Dosage , Side effects.Metoprolol Succinate: Uses, Dosage , Side effects.
Metoprolol Succinate: Uses, Dosage , Side effects.
 
antihypertensive_agent
antihypertensive_agentantihypertensive_agent
antihypertensive_agent
 
Cardiovascular Drugs-Medicinal Chemistry MANIK
Cardiovascular Drugs-Medicinal Chemistry MANIKCardiovascular Drugs-Medicinal Chemistry MANIK
Cardiovascular Drugs-Medicinal Chemistry MANIK
 
Metoprolol (ellen soyombo) final
Metoprolol (ellen soyombo) finalMetoprolol (ellen soyombo) final
Metoprolol (ellen soyombo) final
 
From eye drops to icu, a case report of three side effects of ophthalmic timo...
From eye drops to icu, a case report of three side effects of ophthalmic timo...From eye drops to icu, a case report of three side effects of ophthalmic timo...
From eye drops to icu, a case report of three side effects of ophthalmic timo...
 
CVS-_Antihypertensives-_Beta_blockers.pdf
CVS-_Antihypertensives-_Beta_blockers.pdfCVS-_Antihypertensives-_Beta_blockers.pdf
CVS-_Antihypertensives-_Beta_blockers.pdf
 
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
2969e0d66a077c285b71d2a82dff426b474653b7 (1).ppt
 
Pharmaceutical care plan
Pharmaceutical care planPharmaceutical care plan
Pharmaceutical care plan
 
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
ALL ABOUT HYPERTENSION FOR OMF SURGEONS part 2
 
Hypertension - Role of Azilsartan ( Case based & Evidence based)
Hypertension  - Role of Azilsartan ( Case based & Evidence based)Hypertension  - Role of Azilsartan ( Case based & Evidence based)
Hypertension - Role of Azilsartan ( Case based & Evidence based)
 
Anti htn drugs
Anti htn drugsAnti htn drugs
Anti htn drugs
 
Antiarrhythmic taste smell disturbances 1
Antiarrhythmic taste smell disturbances 1Antiarrhythmic taste smell disturbances 1
Antiarrhythmic taste smell disturbances 1
 
Bronchoconstrictor Drugs
Bronchoconstrictor Drugs Bronchoconstrictor Drugs
Bronchoconstrictor Drugs
 
Beta blocker dr. kiran..
Beta blocker dr. kiran..Beta blocker dr. kiran..
Beta blocker dr. kiran..
 
7.c v s
7.c v s 7.c v s
7.c v s
 
7.cvs
7.cvs7.cvs
7.cvs
 
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
drugs that affect the autonomic nervous system.ppt [autosaved] [autosaved]
 
ECT .pptx
ECT .pptxECT .pptx
ECT .pptx
 
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docxASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
ASSESSMENT AND PLANNING GUIDE FOR USE IN THE HOSPITALThe followi.docx
 
Beta adrenergic blockers
Beta adrenergic blockersBeta adrenergic blockers
Beta adrenergic blockers
 

Recently uploaded

Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
19various
 
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
Donc Test
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
Dhayanithi C
 
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in IndiaTop Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
SwisschemDerma
 
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
rightmanforbloodline
 
Adhd Medication Shortage Uk - trinexpharmacy.com
Adhd Medication Shortage Uk - trinexpharmacy.comAdhd Medication Shortage Uk - trinexpharmacy.com
Adhd Medication Shortage Uk - trinexpharmacy.com
reignlana06
 
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdfCHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
rishi2789
 
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachIntegrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Ayurveda ForAll
 
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPromoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
PsychoTech Services
 
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdfCHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
rishi2789
 
THERAPEUTIC ANTISENSE MOLECULES .pptx
THERAPEUTIC ANTISENSE MOLECULES    .pptxTHERAPEUTIC ANTISENSE MOLECULES    .pptx
THERAPEUTIC ANTISENSE MOLECULES .pptx
70KRISHPATEL
 
CBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdfCBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdf
suvadeepdas911
 
Aortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 BernAortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 Bern
suvadeepdas911
 
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in IndiaTop 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Swastik Ayurveda
 
Best Ayurvedic medicine for Gas and Indigestion
Best Ayurvedic medicine for Gas and IndigestionBest Ayurvedic medicine for Gas and Indigestion
Best Ayurvedic medicine for Gas and Indigestion
Swastik Ayurveda
 
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdfCHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
rishi2789
 
Efficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in AyurvedaEfficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in Ayurveda
Dr. Jyothirmai Paindla
 
Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)
Josep Vidal-Alaball
 
Complementary feeding in infant IAP PROTOCOLS
Complementary feeding in infant IAP PROTOCOLSComplementary feeding in infant IAP PROTOCOLS
Complementary feeding in infant IAP PROTOCOLS
chiranthgowda16
 
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptxVestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Dr. Rabia Inam Gandapore
 

Recently uploaded (20)

Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
 
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
 
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in IndiaTop Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
 
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
 
Adhd Medication Shortage Uk - trinexpharmacy.com
Adhd Medication Shortage Uk - trinexpharmacy.comAdhd Medication Shortage Uk - trinexpharmacy.com
Adhd Medication Shortage Uk - trinexpharmacy.com
 
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdfCHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 1_ANTI TB DRUGS.pdf
 
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachIntegrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
 
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPromoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
 
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdfCHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
CHEMOTHERAPY_RDP_CHAPTER 4_ANTI VIRAL DRUGS.pdf
 
THERAPEUTIC ANTISENSE MOLECULES .pptx
THERAPEUTIC ANTISENSE MOLECULES    .pptxTHERAPEUTIC ANTISENSE MOLECULES    .pptx
THERAPEUTIC ANTISENSE MOLECULES .pptx
 
CBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdfCBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdf
 
Aortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 BernAortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 Bern
 
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in IndiaTop 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in India
 
Best Ayurvedic medicine for Gas and Indigestion
Best Ayurvedic medicine for Gas and IndigestionBest Ayurvedic medicine for Gas and Indigestion
Best Ayurvedic medicine for Gas and Indigestion
 
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdfCHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
 
Efficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in AyurvedaEfficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in Ayurveda
 
Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)
 
Complementary feeding in infant IAP PROTOCOLS
Complementary feeding in infant IAP PROTOCOLSComplementary feeding in infant IAP PROTOCOLS
Complementary feeding in infant IAP PROTOCOLS
 
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptxVestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
 

Clinical Case 6

  • 1.
  • 2.  A 70-Year-old man is seen in follow-up at your office after he has been hospitalized for a myocardial infarction. He underwent successful angioplasty and is currently asymptomatic. Prior to his MI, he was not on medications. He is not a smoker and is not diabetic. During his hospitalization, he was noted to have persistently elevated blood pressure readings. He had asthma as a child, but has not had any recent wheezing episodes . While in the hospital, he was started on oral metoprolol.
  • 3. Questions 1. Metoprolol is selective for which adrenoceptor? 2. What effects do agents such as metoprolol have on the cardiovascular system? 3. In which organ is metoprolol primarily metabolized? 4. Why must beta adrenergic antagonists be used with caution in asthmatics?
  • 4. Summary  A 70-year-old hypertensive man with a childhood history of asthma had a recent myocardial infarction and is prescribed metoprolol
  • 6. Effect of beta adrenoceptor antagonists on the cardiovascular system  Reduction of sympathetic-stimulated increases in heart rate, contractility and cardiac output  Lower BP as a result of effects on heart, renin- angiotensin system, and CNS  Increased atrioventricular (AV) conduction time and refractoriness.
  • 7. Organ in which metoprolol is metabolized Liver
  • 8. Reason for caution in use in asthhmatics  Blockade of beta 2 adrenoceptor in bronchial smooth muscle may cause increased airway resistance and bronchospasm