This document summarizes the development of scientific thought and method. It describes the differences between rationalism, which relies on reason as the source of knowledge, and empiricism, which relies on experience and sensory observation. It discusses key figures like Aristotle, Galileo, and Francesco Redi, and how they helped establish scientific methods like experimentation and control conditions. The scientific method is presented as a systematic process of making observations, developing hypotheses and predictions, conducting experiments to test hypotheses, and analyzing results to either support hypotheses or generate new facts and hypotheses.