Cellular cycle is important in cell growth, development, and death. Studying this area helps understand diseases associated with these processes. Researchers identified the cell of origin in leukemia cases using mouse experiments expressing MLL-AF2. They analyzed different cell states in mice and a control group. Further studies may open new avenues for early cancer diagnosis and treatment. A gene mutation was found to cause brittle bone disease and other connective tissue issues in two families, showing one gene can cause multiple diseases. These studies increase understanding of known diseases and could reveal unknown ones, expanding human knowledge.