Juan Carlos Torres Sánchez #804-11-9230 BIOL 3095 Seminar 3 on MetabolomicsOn September 6,Leiddy Alvarado offered a seminar about metabolic studies in breastcancer patients. The main goal of the research is identifying a way to discover anearly prognosis of breast cancer. Something many people don’t know is that whencancer survivor patients are in remission it means that they are not cured, but for themoment there is no visible recurrence of the cancer. Leiddy Alvarado’s researchspecializes in finding biomarkers for the early detection of breast cancer recurrence inpatients. The techniques used were MS and NMR (nuclear magnetic resonance).Thislast one is new to me. The combination of both techniques helps to identifyspecific biomarkers with more specificity and sensitivity. Specificity isdefinedas theprobability that a testlet’sa person know that they do not have the disease. Sensitivityis the probability that a testtells a person it has the disease when in fact they do havethe disease. The analysis for sensitivity and specificity is an important aspect of thisproject because with them the result is more precise and efficient. ResearchemployingMetabolic techniques, such as NMR and MS, utilizes a lot of analyticalchemistry.The results of this research are the identification of eleven biomarkers that could bepotential biomarkers for early breast cancer prognosis. The experiment is still in thevalidation stage, but regardless, it passed a pre validation giving hope that thisresearch is going down the right path. If this experiment is completed and theprocedure marketed, patients with a simple blood test would know their prognosiswithout having to go through invasive surgery, or spending a great deal of money.That would be a great advantage. Also, Metabolomic studies can be used for other
diseases instead of cancer. For example, it can help detect biomarkers for certaindiseases, such as Lou Gehrig’s disease.Leiddy Alvarez was a great speaker and her motivation was really effective. I willnever forget what she repeated: “Keep on going, never give up” and “Take risks”.