Ian Gordon, Paul Zelisko, Brock Library

1. +
Ian Gordon
CHEM 2P21
Information
Exercise
March 23, 2020
Happy
Pearl Jacobson, Science Librarian,

12. 1. Download and open ChemDraw
2. Search by chemical/drug by name and insert structure
3. Click on A text box and type in name
4. Centre and/or click on lasso or marquee box to drag text
box and structure
5. Play about and learn the basics or watch any number of tutorial(s)
6. Copy/Scan and paste into Word

29. Xie, H.; Hao, H.; Xu, N.; Liang, X.; Gao, D.; Xu, Y.; Gao, Y.; Tao, H.; Wong, M.
Pharmaceuticals and Personal Care Products in Water, Sediments, Aquatic
Organisms, and Fish Feeds in the Pearl River Delta: Occurrence,
Distribution, Potential Sources, and Health Risk Assessment. Sci. Total
Environ. 2019, 659, 230–239. https://doi.org/10.1016/j.scitotenv.2018.12.222.

34. Napoleon, J. V. ; Manheri, M. K. Direct Transformation of Baylis-
Hillman Acetates into N-Substituted Quinolones through an…
Oxidation Sequence. Synthesis 2011, 20, 3379-3388.

37. Napoleon, J. V.; Manheri, M. K. Direct Transformation of
Baylis-Hillman Acetates into N-Substituted Quinolones
through an SN2′ → SNAr → (Δ3,4-Δ2,3 Shift) → Oxidation
Sequence. Synthesis 2011, 20, 3379-3388.

43. Yachao, L. Chemical Synthesis Method for Norfloxacin. Patent
Application CN 107445892, 2017.

49. Learning Outcomes:
• search SciFinder, Reaxys chemistry and Espacenet patent databases
• use small molecule databases including PubChem, ChemSpider Drugs.com
• accessing commercial chemical manufacturing suppliers e.g. Sigma-Aldrich
• determining whether to make or purchase chemical compounds
• register, download and use ChemDraw chemical drawing software
• search biochemical, chemistry, medical and biological science databases for scholarly articles
• appreciate how best to search the scholarly literature using chemical compounds, structures, names…
• explore and use Brock’s New ACS Guide to Scholarly Communication digital resource
• be better informed of biochemical research on antibiotics / antibacterial drug development, their chemical
properties, reactions, and regulatory information
• analyze and comment on pharmaceutical concepts fundamental to global health and green chemistry

50. +
Ian Gordon
CHEM 2P21
Information
Exercise
March 28, 2018
Happy
Pearl Jacobson, Science Librarian,