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CHEM 2P21 Information exercise Winter 2019 ppt slides

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Paul Zelisko Brock Course Information Assignment March 27, 2019

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CHEM 2P21 Information exercise Winter 2019 ppt slides

  1. 1. + Ian Gordon CHEM 2P21 Information Exercise March 27, 2019 Happy Pearl Jacobson, Science Librarian,
  2. 2. 1. Download and open ChemDraw 2. Search by chemical/drug by name and insert structure 3. Click on A text box and type in name 4. Centre and/or click on lasso or marquee box to drag text box and structure 5. Play about and learn the basics or watch any number of tutorial(s) 6. Copy/Scan and paste into Word
  3. 3. Napoleon, J. V. ; Manheri, M. K. Direct Transformation of Baylis- Hillman Acetates into N-Substituted Quinolones through an… Oxidation Sequence. Synthesis 2011, 20, 3379-3388.
  4. 4. Napoleon, J. V.; Manheri, M. K. Direct Transformation of Baylis-Hillman Acetates into N-Substituted Quinolones through an SN2′ → SNAr → (Δ3,4-Δ2,3 Shift) → Oxidation Sequence. Synthesis 2011, 20, 3379-3388.
  5. 5. Yachao, L. Chemical Synthesis Method for Norfloxacin. Patent Application CN 107445892, 2017.
  6. 6. New to this exercise: • searching Reaxys chemistry and Espacenet patent databases • consulting small molecule databases including PubChem, ChemSpider Drugs.com • using commercial chemical manufacturing suppliers e.g. Sigma-Aldrich • register, download and use ChemDraw chemical drawing software • be better informed of biochemical research on antibiotics / antibacterial drug development, their chemical properties, reactions, regulatory and scholarly information. • define and comment on concepts fundamental to green chemistry.
  7. 7. + Ian Gordon CHEM 2P21 Information Exercise March 28, 2018 Happy Pearl Jacobson, Science Librarian,

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