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NEUROPATHIC ARTHRITIS
- SHEETAL PAI
2ND MPT
(ORTHOPAEDICS)
INTRODUCTION
Progressive, non-infectious neuro-osteoarthropathy destruction of
the foot architecture
Inflammatory condition osteolysis
Commonly presents in the midfoot but also occurs in forefoot and hindfoot
ETIOLOGY
Diabetes mellitus the most common
Has been associated with:
Autonomic neuroarthropathy,
Infection (leprosy, HIV),
Toxic exposure (ethanol, drug related),
Rheumatoid arthritis,
Multiple sclerosis,
Congenital neuropathy,
Tabes dorsalis,
Traumatic injury,
Metabolic abnormalities and syringomyelia
PATHOPHYSIOLOGY
NEUROTRAUMATIC THEORY NEUROVASCULAR THEORY
STAGES OF CHARCOT ARTHROPATHY
(EICHENHOLTZ)
STAGE SIGNS AND
SYMPTOMS
RADIOGRAPHS
0: Clinical
(prefragmentation)
Acute inflammation Normal radiographs
1: Dissolution
(fragmentation)
Acute inflammation,
swelling,erythema,
warmth
Osteopenia, fragmentation,
joint subluxation or dislocation
2: Coalescence Less inflammation, less
swelling, less erythema
Absorption of bone debris,
sclerosis, fusion of larger
fragments
3. Resolution Resolved erythema,
swelling and warmth;
consolidation of healing
Smoothed bony edges; bony/
fibrous ankylosis, consolidation
of deformity
Anatomical classification(Brodsky)
Brodsky Type I (midfoot) naviculocuneiform and
metatarsocuneiform joints(60%)
Type II (hindfoot) subtalar, talonavicular, or
calcaneocuboid joints (30-35%)
Type III :
Type IIIA tibiotalar joint and associated bones
Type IIIB pathologic fracture of the tuberosity of
the calcaneus.
IMAGING AND DIAGNOSTIC
LAB : WBC, ESR
IMAGING : Radiographs, Bone scan, Ultrasound , MRI
OTHERS: Synovial biopsy, bone probe
TREATMENT
Eichenholtz stage 0 : frequent follow-up
patient education on diabetic foot care
protected weight bearing
Eichenholtz stage I : protected weight bearing with
total contact casting or prefabricated pneumatic brace
Eichenholtz Stage II : Total contact casting, prefabricated
pneumatic brace, Charcot restraint orthotic walker or clamshell
AFO
Eichenholtz Stage III
if the foot is if the foot is with osteomyelitis
plantigrade non-plantigrade /
recurrent history
of ulcerations surgical debridement
patient can use or amputation
custom inlay shoes
debridement,
exostectomy,correction,
or fusion with
internal fixation
THANKYOU

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  • 1. NEUROPATHIC ARTHRITIS - SHEETAL PAI 2ND MPT (ORTHOPAEDICS)
  • 2. INTRODUCTION Progressive, non-infectious neuro-osteoarthropathy destruction of the foot architecture Inflammatory condition osteolysis Commonly presents in the midfoot but also occurs in forefoot and hindfoot
  • 3. ETIOLOGY Diabetes mellitus the most common Has been associated with: Autonomic neuroarthropathy, Infection (leprosy, HIV), Toxic exposure (ethanol, drug related), Rheumatoid arthritis, Multiple sclerosis, Congenital neuropathy, Tabes dorsalis, Traumatic injury, Metabolic abnormalities and syringomyelia
  • 5. STAGES OF CHARCOT ARTHROPATHY (EICHENHOLTZ) STAGE SIGNS AND SYMPTOMS RADIOGRAPHS 0: Clinical (prefragmentation) Acute inflammation Normal radiographs 1: Dissolution (fragmentation) Acute inflammation, swelling,erythema, warmth Osteopenia, fragmentation, joint subluxation or dislocation 2: Coalescence Less inflammation, less swelling, less erythema Absorption of bone debris, sclerosis, fusion of larger fragments 3. Resolution Resolved erythema, swelling and warmth; consolidation of healing Smoothed bony edges; bony/ fibrous ankylosis, consolidation of deformity
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  • 7. Anatomical classification(Brodsky) Brodsky Type I (midfoot) naviculocuneiform and metatarsocuneiform joints(60%) Type II (hindfoot) subtalar, talonavicular, or calcaneocuboid joints (30-35%) Type III : Type IIIA tibiotalar joint and associated bones Type IIIB pathologic fracture of the tuberosity of the calcaneus.
  • 8. IMAGING AND DIAGNOSTIC LAB : WBC, ESR IMAGING : Radiographs, Bone scan, Ultrasound , MRI OTHERS: Synovial biopsy, bone probe
  • 9. TREATMENT Eichenholtz stage 0 : frequent follow-up patient education on diabetic foot care protected weight bearing Eichenholtz stage I : protected weight bearing with total contact casting or prefabricated pneumatic brace Eichenholtz Stage II : Total contact casting, prefabricated pneumatic brace, Charcot restraint orthotic walker or clamshell AFO
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  • 12. Eichenholtz Stage III if the foot is if the foot is with osteomyelitis plantigrade non-plantigrade / recurrent history of ulcerations surgical debridement patient can use or amputation custom inlay shoes debridement, exostectomy,correction, or fusion with internal fixation