This document discusses diabetes and its effects on the orthopedic system, with a focus on the diabetic foot. It covers the pathophysiology of diabetes and how it can lead to complications like neuropathy, vasculopathy, and immunopathy. These complications increase the risk of issues like diabetic foot ulcers and Charcot arthropathy. The document outlines treatments for various conditions like total contact casting, antibiotics, and surgery. It also describes classifications of diabetic foot ulcers and Charcot arthropathy to help guide treatment decisions.
Diabetes can cause many complications affecting the feet including neuropathy, vasculopathy, and immunopathy which increase risks for foot ulcers and infections. Neuropathy damages nerves through multiple pathways like reactive oxygen species, impairing sensation and motor function. Vasculopathy damages blood vessels increasing risks of ischemia. Immunopathy impairs immune response to infection. Charcot arthropathy is a condition where loss of autonomic control and sensation leads to repetitive micro-trauma and bone destruction in the foot. Treatment involves wound care, offloading pressure through casting, surgery to correct deformities or remove infected tissue, and managing underlying complications of diabetes.
This document provides an overview of peripheral neuropathies. It discusses that peripheral neuropathies can involve sensory nerves, motor nerves, or both, and may affect single or multiple nerves. The document then covers the clinical presentation and classification of different types of neuropathies, including those that primarily affect the cell body, myelin, or axon. It also lists common causes of peripheral neuropathies like diabetes, paraproteinemia, alcohol misuse, and discusses their prevalence. The temporal course, symptoms, and assessment of peripheral neuropathies are discussed in detail.
Neuropathic arthropathy, also known as Charcot arthropathy, is a condition characterized by progressive joint destruction and deformity caused by loss of sensation in the joints. It is most commonly seen in patients with diabetes or neurological disorders. The main theories for its pathophysiology are neurotrauma from repetitive micro-injuries without pain perception, and neurovascular changes that increase bone resorption. Treatment involves initial casting to immobilize the joint, followed by bracing, orthotics, and immobilization over the course of 1-2 years to allow healing. Surgical options like fusion or reconstruction may be used for advanced cases or deformity correction.
Pruritus, or itch, is a sensation that provokes the desire to scratch. Chronic pruritus lasts more than 6 weeks and can be caused by skin diseases or systemic diseases. Itch is transmitted through unmyelinated C fibers and is a distinct sensation from pain. Scratching provides temporary relief by stimulating myelinated fibers or damaging sensory nerve endings. Management of pruritus involves general skin care, topical agents like corticosteroids, calcineurin inhibitors, local anesthetics, and antihistamines, as well as treating any underlying cause.
This 62-year-old lady presented with 5 days of painful right knee associated with redness and limping after trauma to the knee. Examination found fullness, redness, tenderness, warmth and restricted movement of the right knee. Differential diagnoses included fracture, septic arthritis, and allergy.
This 62-year-old lady presented with 5 days of painful right knee associated with redness and limping after trauma to the knee. Examination found fullness, redness, tenderness, warmth and restricted movement of the right knee. Differential diagnoses included fracture, septic arthritis, and allergy.
Approach to patient with peripheral neuropathyDrAnusha3
This document provides an overview of approaches to evaluating and diagnosing peripheral neuropathy. It discusses 9 patterns seen in peripheral neuropathy and the key considerations for each. The patterns include distal symmetric, asymmetric distal weakness, proximal and distal symmetric involvement, asymmetric proximal and distal weakness, asymmetric distal weakness without sensory loss, symmetric weakness without sensory loss, symmetric sensory loss and distal areflexia, asymmetric proprioceptive sensory loss without weakness, and autonomic symptoms and signs. For each pattern, common causes are outlined along with important historical and examination findings.
This document discusses diabetes and its effects on the orthopedic system, with a focus on the diabetic foot. It covers the pathophysiology of diabetes and how it can lead to complications like neuropathy, vasculopathy, and immunopathy. These complications increase the risk of issues like diabetic foot ulcers and Charcot arthropathy. The document outlines treatments for various conditions like total contact casting, antibiotics, and surgery. It also describes classifications of diabetic foot ulcers and Charcot arthropathy to help guide treatment decisions.
Diabetes can cause many complications affecting the feet including neuropathy, vasculopathy, and immunopathy which increase risks for foot ulcers and infections. Neuropathy damages nerves through multiple pathways like reactive oxygen species, impairing sensation and motor function. Vasculopathy damages blood vessels increasing risks of ischemia. Immunopathy impairs immune response to infection. Charcot arthropathy is a condition where loss of autonomic control and sensation leads to repetitive micro-trauma and bone destruction in the foot. Treatment involves wound care, offloading pressure through casting, surgery to correct deformities or remove infected tissue, and managing underlying complications of diabetes.
This document provides an overview of peripheral neuropathies. It discusses that peripheral neuropathies can involve sensory nerves, motor nerves, or both, and may affect single or multiple nerves. The document then covers the clinical presentation and classification of different types of neuropathies, including those that primarily affect the cell body, myelin, or axon. It also lists common causes of peripheral neuropathies like diabetes, paraproteinemia, alcohol misuse, and discusses their prevalence. The temporal course, symptoms, and assessment of peripheral neuropathies are discussed in detail.
Neuropathic arthropathy, also known as Charcot arthropathy, is a condition characterized by progressive joint destruction and deformity caused by loss of sensation in the joints. It is most commonly seen in patients with diabetes or neurological disorders. The main theories for its pathophysiology are neurotrauma from repetitive micro-injuries without pain perception, and neurovascular changes that increase bone resorption. Treatment involves initial casting to immobilize the joint, followed by bracing, orthotics, and immobilization over the course of 1-2 years to allow healing. Surgical options like fusion or reconstruction may be used for advanced cases or deformity correction.
Pruritus, or itch, is a sensation that provokes the desire to scratch. Chronic pruritus lasts more than 6 weeks and can be caused by skin diseases or systemic diseases. Itch is transmitted through unmyelinated C fibers and is a distinct sensation from pain. Scratching provides temporary relief by stimulating myelinated fibers or damaging sensory nerve endings. Management of pruritus involves general skin care, topical agents like corticosteroids, calcineurin inhibitors, local anesthetics, and antihistamines, as well as treating any underlying cause.
This 62-year-old lady presented with 5 days of painful right knee associated with redness and limping after trauma to the knee. Examination found fullness, redness, tenderness, warmth and restricted movement of the right knee. Differential diagnoses included fracture, septic arthritis, and allergy.
This 62-year-old lady presented with 5 days of painful right knee associated with redness and limping after trauma to the knee. Examination found fullness, redness, tenderness, warmth and restricted movement of the right knee. Differential diagnoses included fracture, septic arthritis, and allergy.
Approach to patient with peripheral neuropathyDrAnusha3
This document provides an overview of approaches to evaluating and diagnosing peripheral neuropathy. It discusses 9 patterns seen in peripheral neuropathy and the key considerations for each. The patterns include distal symmetric, asymmetric distal weakness, proximal and distal symmetric involvement, asymmetric proximal and distal weakness, asymmetric distal weakness without sensory loss, symmetric weakness without sensory loss, symmetric sensory loss and distal areflexia, asymmetric proprioceptive sensory loss without weakness, and autonomic symptoms and signs. For each pattern, common causes are outlined along with important historical and examination findings.
This document discusses peripheral neuropathy, including:
1. It defines peripheral neuropathy and describes the different types that can affect motor, sensory, or autonomic nerves.
2. It outlines various causes of peripheral neuropathies including hereditary, infectious, inflammatory, metabolic, toxic, and more.
3. It describes the clinical presentations of different types of peripheral neuropathies based on the affected nerves and provides examples.
This document provides an overview of how to approach a patient presenting with joint pain. It discusses how the pain may occur only at rest or only with activity. The physical exam aims to localize the source and understand the pathophysiology by assessing for signs of inflammation, functional impairment, swelling, range of motion, and tendon issues. Taking a thorough history is important to generate differential diagnoses and evaluate features like onset, duration, joint involvement, and extra-articular manifestations that may indicate underlying conditions like rheumatoid arthritis or lupus.
This document provides an overview of how to approach a patient with arthritis. It describes common symptoms of arthritis and how to differentiate between inflammatory and non-inflammatory types based on history, physical exam findings, pattern of joint involvement, onset and duration of symptoms, and additional features. It discusses specific types of arthritis like osteoarthritis, gout, pseudogout, septic arthritis, rheumatoid arthritis, seronegative spondyloarthritides, and others. It provides guidance on diagnostic tests, imaging, and treatment approaches for different arthritis conditions.
This document discusses the major complications of diabetes mellitus, including macrovascular complications like coronary artery disease and stroke, microvascular complications affecting the eyes, kidneys, and nerves, and other issues like infections. It provides detailed information on the pathogenesis and management of various complications. The main points are that cardiovascular disease is the leading cause of death in diabetics, and that better control of blood sugar can reduce the risk of developing and progression of complications over time.
approach to joint pain in pediatrics and treatment of join painpptxmadhurathore16
Arthritis in childhood commonly presents as monoarthritis rather than polyarthritis. Acute monoarthritis lasting less than 2 weeks can be caused by septic arthritis, reactive arthritis, hemarthrosis, or trauma. It is important to determine if the child appears systemically well or sick, and consider features suggestive of local or systemic infection, bleeding diathesis, or the nature of symptom onset. A thorough history, examination, and laboratory/radiological investigations can help identify the underlying cause.
I. The peripheral nervous system carries signals between the central nervous system and the rest of the body. It has three main components - cranial, spinal, and autonomic. There are three main types of nerve fibers - A, B, and C - which differ in diameter, myelination, and function.
II. Peripheral neuropathies can be acquired through systemic diseases, trauma, infections, or inherited genetically. Common acquired neuropathies include diabetic neuropathy, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and alcoholic neuropathy. Inherited forms include Charcot-Marie-Tooth disease and hereditary liability to pressure palsies.
This document provides guidance on approaching a case of arthritis by discussing the history, signs, symptoms, patterns, screening tests, and types of arthritis. It outlines the key differences between inflammatory and non-inflammatory arthritis, acute vs chronic presentations, monoarticular vs polyarticular involvement, and symmetric vs asymmetric distribution. Screening tests are recommended based on whether the arthritis presentation is acute polyarthritis, chronic polyarthritis, or diffuse arthralgias and myalgias.
This document summarizes musculoskeletal manifestations and considerations for orthopedic surgeons in patients with diabetes mellitus. It describes increased risks of conditions like limited joint mobility, adhesive capsulitis, Dupuytren's contracture, and diabetic foot complications in diabetics. It also provides classifications and evaluations for diabetic foot ulcers and Charcot neuroarthropathy. Management involves optimizing glycemic control, offloading pressures, wound care, and possible surgery. Surgeons must consider higher risks of infection and impaired healing in diabetic patients.
This document provides an overview of several rheumatological conditions including osteoarthritis, rheumatoid arthritis, systemic lupus erythematosus, and seronegative arthritides such as reactive arthritis, ankylosing spondylitis, and enteropathic arthritis. Key details are provided on the epidemiology, pathology, signs and symptoms, investigations, and management of each condition. The document is intended as a guide for an OSCE station on rheumatology topics.
The document discusses various types of peripheral neuropathy, including definitions, mechanisms of damage, classification based on examination findings, associated laboratory and diagnostic testing, and treatment approaches. Peripheral neuropathy can be caused by numerous systemic diseases and conditions and presents with a variety of symptoms depending on the affected nerve fibers and distribution of the neuropathy. A thorough evaluation is required to determine the underlying cause and guide management strategies.
Approach towards a case of musculoskeletal disorder.#sirmohit
This document provides guidance for doctors on evaluating musculoskeletal complaints during initial patient encounters. It describes determining if the issue is articular or peri-articular, inflammatory or non-inflammatory, acute or chronic, and localized or widespread. Characteristics of articular vs. nonarticular disorders are outlined. Inflammatory conditions are distinguished from mechanical issues based on factors like stiffness, pain, and physical findings. Acute vs. chronic disorders are defined as less or greater than 6 weeks respectively. Extent of joint involvement from monoarticular to polyarticular is also addressed. Rheumatoid arthritis diagnosis criteria and distinguishing features from similar conditions are reviewed. Investigations like blood tests, synovial fluid analysis, and imaging are also summarized
The document discusses seronegative and seropositive spondyloarthropathies. It describes the key characteristics of several types of spondyloarthropathies including ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and arthritis associated with inflammatory bowel disease. Imaging findings are an important part of diagnosis and include changes in the sacroiliac joints and spine seen on radiography as well as MRI findings. HLA-B27 positivity is also discussed as a predictor for some types.
Peripheral neuropathy is damage to the peripheral nervous system, affecting nerves outside of the brain and spinal cord. It can be caused by diseases of the nerves themselves or systemic illness. There are several types including mononeuropathy (affecting a single nerve), mononeuritis multiplex (affecting multiple individual nerves), and polyneuropathy (affecting many nerves symmetrically). Common causes include diabetes, alcohol use, toxins, genetics, and metabolic conditions. Symptoms vary depending on the type and nerves involved but may include pain, numbness, tingling, muscle weakness and loss of sensation. Diagnosis involves clinical exams, nerve conduction tests, and identifying underlying causes. Treatment focuses on managing the cause, treating pain symptoms
A short review of rheumatological diseases.
Rheumatoid Arthritis, Gout, Ankylosing Spondylitis, Systemic Sclerosis, Behcet Disease, Osteoarthritis, etc.
Rheumatoid arthritis and osteoarthritis are common forms of arthritis. Rheumatoid arthritis is a systemic inflammatory disease that affects the joints and other organs, causing progressive joint deformity if not treated early. It can be a potentially fatal illness with increased risks of infections, renal impairment and cardiovascular disease. Osteoarthritis is the most common joint disorder and affects older individuals, particularly the weight-bearing joints like the hips and knees. It involves the breakdown of cartilage and bone within a joint. Management of both conditions involves conservative measures as well as medications aimed at reducing pain and inflammation.
Charcot joint or neuropathic joint are destructed joint occurs in Diabetes, syphilis, syringomyelia , leprosy, AMLS, Peripheral neuropathy and any condition leads to impair sensation of peripheral part of body
1) Myalgia, or muscle pain, is a common complaint that can be caused by exertion, trauma, or viral infections. It may indicate underlying disorders.
2) Causes of myalgia include infections, rheumatic diseases, medications, endocrine disorders, and psychiatric conditions. Localized myalgia can be from overuse, soft tissue issues, or compartment syndrome.
3) Evaluation of myalgia involves history of symptoms and onset, exam of muscles and other systems, and sometimes imaging or labs. Management depends on cause but may include heat, rest, analgesics, and NSAIDs.
Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of internal Medicine, Immunology, rheumatology and allergy
How to approach a musculoskeletal pain step by step?
Differentiating different rheumatic diseases
This document discusses peripheral neuropathy, including:
1. It defines peripheral neuropathy and describes the different types that can affect motor, sensory, or autonomic nerves.
2. It outlines various causes of peripheral neuropathies including hereditary, infectious, inflammatory, metabolic, toxic, and more.
3. It describes the clinical presentations of different types of peripheral neuropathies based on the affected nerves and provides examples.
This document provides an overview of how to approach a patient presenting with joint pain. It discusses how the pain may occur only at rest or only with activity. The physical exam aims to localize the source and understand the pathophysiology by assessing for signs of inflammation, functional impairment, swelling, range of motion, and tendon issues. Taking a thorough history is important to generate differential diagnoses and evaluate features like onset, duration, joint involvement, and extra-articular manifestations that may indicate underlying conditions like rheumatoid arthritis or lupus.
This document provides an overview of how to approach a patient with arthritis. It describes common symptoms of arthritis and how to differentiate between inflammatory and non-inflammatory types based on history, physical exam findings, pattern of joint involvement, onset and duration of symptoms, and additional features. It discusses specific types of arthritis like osteoarthritis, gout, pseudogout, septic arthritis, rheumatoid arthritis, seronegative spondyloarthritides, and others. It provides guidance on diagnostic tests, imaging, and treatment approaches for different arthritis conditions.
This document discusses the major complications of diabetes mellitus, including macrovascular complications like coronary artery disease and stroke, microvascular complications affecting the eyes, kidneys, and nerves, and other issues like infections. It provides detailed information on the pathogenesis and management of various complications. The main points are that cardiovascular disease is the leading cause of death in diabetics, and that better control of blood sugar can reduce the risk of developing and progression of complications over time.
approach to joint pain in pediatrics and treatment of join painpptxmadhurathore16
Arthritis in childhood commonly presents as monoarthritis rather than polyarthritis. Acute monoarthritis lasting less than 2 weeks can be caused by septic arthritis, reactive arthritis, hemarthrosis, or trauma. It is important to determine if the child appears systemically well or sick, and consider features suggestive of local or systemic infection, bleeding diathesis, or the nature of symptom onset. A thorough history, examination, and laboratory/radiological investigations can help identify the underlying cause.
I. The peripheral nervous system carries signals between the central nervous system and the rest of the body. It has three main components - cranial, spinal, and autonomic. There are three main types of nerve fibers - A, B, and C - which differ in diameter, myelination, and function.
II. Peripheral neuropathies can be acquired through systemic diseases, trauma, infections, or inherited genetically. Common acquired neuropathies include diabetic neuropathy, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and alcoholic neuropathy. Inherited forms include Charcot-Marie-Tooth disease and hereditary liability to pressure palsies.
This document provides guidance on approaching a case of arthritis by discussing the history, signs, symptoms, patterns, screening tests, and types of arthritis. It outlines the key differences between inflammatory and non-inflammatory arthritis, acute vs chronic presentations, monoarticular vs polyarticular involvement, and symmetric vs asymmetric distribution. Screening tests are recommended based on whether the arthritis presentation is acute polyarthritis, chronic polyarthritis, or diffuse arthralgias and myalgias.
This document summarizes musculoskeletal manifestations and considerations for orthopedic surgeons in patients with diabetes mellitus. It describes increased risks of conditions like limited joint mobility, adhesive capsulitis, Dupuytren's contracture, and diabetic foot complications in diabetics. It also provides classifications and evaluations for diabetic foot ulcers and Charcot neuroarthropathy. Management involves optimizing glycemic control, offloading pressures, wound care, and possible surgery. Surgeons must consider higher risks of infection and impaired healing in diabetic patients.
This document provides an overview of several rheumatological conditions including osteoarthritis, rheumatoid arthritis, systemic lupus erythematosus, and seronegative arthritides such as reactive arthritis, ankylosing spondylitis, and enteropathic arthritis. Key details are provided on the epidemiology, pathology, signs and symptoms, investigations, and management of each condition. The document is intended as a guide for an OSCE station on rheumatology topics.
The document discusses various types of peripheral neuropathy, including definitions, mechanisms of damage, classification based on examination findings, associated laboratory and diagnostic testing, and treatment approaches. Peripheral neuropathy can be caused by numerous systemic diseases and conditions and presents with a variety of symptoms depending on the affected nerve fibers and distribution of the neuropathy. A thorough evaluation is required to determine the underlying cause and guide management strategies.
Approach towards a case of musculoskeletal disorder.#sirmohit
This document provides guidance for doctors on evaluating musculoskeletal complaints during initial patient encounters. It describes determining if the issue is articular or peri-articular, inflammatory or non-inflammatory, acute or chronic, and localized or widespread. Characteristics of articular vs. nonarticular disorders are outlined. Inflammatory conditions are distinguished from mechanical issues based on factors like stiffness, pain, and physical findings. Acute vs. chronic disorders are defined as less or greater than 6 weeks respectively. Extent of joint involvement from monoarticular to polyarticular is also addressed. Rheumatoid arthritis diagnosis criteria and distinguishing features from similar conditions are reviewed. Investigations like blood tests, synovial fluid analysis, and imaging are also summarized
The document discusses seronegative and seropositive spondyloarthropathies. It describes the key characteristics of several types of spondyloarthropathies including ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and arthritis associated with inflammatory bowel disease. Imaging findings are an important part of diagnosis and include changes in the sacroiliac joints and spine seen on radiography as well as MRI findings. HLA-B27 positivity is also discussed as a predictor for some types.
Peripheral neuropathy is damage to the peripheral nervous system, affecting nerves outside of the brain and spinal cord. It can be caused by diseases of the nerves themselves or systemic illness. There are several types including mononeuropathy (affecting a single nerve), mononeuritis multiplex (affecting multiple individual nerves), and polyneuropathy (affecting many nerves symmetrically). Common causes include diabetes, alcohol use, toxins, genetics, and metabolic conditions. Symptoms vary depending on the type and nerves involved but may include pain, numbness, tingling, muscle weakness and loss of sensation. Diagnosis involves clinical exams, nerve conduction tests, and identifying underlying causes. Treatment focuses on managing the cause, treating pain symptoms
A short review of rheumatological diseases.
Rheumatoid Arthritis, Gout, Ankylosing Spondylitis, Systemic Sclerosis, Behcet Disease, Osteoarthritis, etc.
Rheumatoid arthritis and osteoarthritis are common forms of arthritis. Rheumatoid arthritis is a systemic inflammatory disease that affects the joints and other organs, causing progressive joint deformity if not treated early. It can be a potentially fatal illness with increased risks of infections, renal impairment and cardiovascular disease. Osteoarthritis is the most common joint disorder and affects older individuals, particularly the weight-bearing joints like the hips and knees. It involves the breakdown of cartilage and bone within a joint. Management of both conditions involves conservative measures as well as medications aimed at reducing pain and inflammation.
Charcot joint or neuropathic joint are destructed joint occurs in Diabetes, syphilis, syringomyelia , leprosy, AMLS, Peripheral neuropathy and any condition leads to impair sensation of peripheral part of body
1) Myalgia, or muscle pain, is a common complaint that can be caused by exertion, trauma, or viral infections. It may indicate underlying disorders.
2) Causes of myalgia include infections, rheumatic diseases, medications, endocrine disorders, and psychiatric conditions. Localized myalgia can be from overuse, soft tissue issues, or compartment syndrome.
3) Evaluation of myalgia involves history of symptoms and onset, exam of muscles and other systems, and sometimes imaging or labs. Management depends on cause but may include heat, rest, analgesics, and NSAIDs.
Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of internal Medicine, Immunology, rheumatology and allergy
How to approach a musculoskeletal pain step by step?
Differentiating different rheumatic diseases
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This document discusses various types of airway devices including nasopharyngeal airways, oropharyngeal airways like Guedel and Berman, and endotracheal tubes. It provides details on the purpose, construction, sizes, indications, contraindications and complications of these devices. Tracheostomy tubes are also summarized, including their parts, advantages over endotracheal tubes, and potential complications. Proper tracheostomy care is outlined.
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This document provides definitions and concepts related to mechanical ventilation. It begins by defining basic terminology like pressures, pressure gradients, and types of ventilation. It then discusses normal breathing mechanics and how mechanical ventilation works. The rest of the document defines various pressures involved in ventilation, describes different modes and settings, and discusses how to monitor patients on ventilators.
Core Dysfunction in children with CP.pptxHanineHassan2
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2. Physical therapy must address both excessive muscle co-contraction and periods of no contraction. Treatment techniques and strategies need to change frequently due to variability in muscle tone.
3. Impairments in athetoid CP include difficulty controlling muscle contractions for movement initiation and termination, abnormal timing and initiation of movements, and limited use of muscle synergies for posture and movement.
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The document discusses the application of ergonomics in designing equipment and playing surfaces for racket sports. It covers considerations for designing tennis rackets, balls, footwear, and playing surfaces. For tennis rackets, attributes like head size, string pattern, weight, balance, stiffness, and string tension are discussed. Characteristics of tennis balls for different court surfaces are also outlined. The document then summarizes biomechanical factors and considerations for shoe design for different surfaces.
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Medical ionization is a technique that introduces therapeutic ions into tissues using direct current. Positive ions are repelled into tissues under the anode, while negative ions are repelled under the cathode. An experiment in 1903 proved ions enter tissues - when rabbits were connected to a current, the rabbit with strychnine ions under the anode died, showing ion entry. Various ions like iodine, zinc, and histamine can be used, having effects like counterirritation, tissue destruction, or vasodilation. The technique involves soaking pads in salt solutions of the desired ion and applying one pad and electrode to the treatment area.
A stroke is caused by an interruption of blood flow to the brain and results in the rapid onset of neurological symptoms. There are two main types of stroke: ischemic, due to blockage of a blood vessel, and hemorrhagic, due to bleeding. Assessment focuses on the symptoms, their progression over time, and functional abilities. Treatment goals are to prevent complications, improve mobility and strength, and regain independence with daily living activities.
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• Equipping health professionals to address questions, concerns and health misinformation
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The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
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These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
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3. ETIOLOGY
Diabetes mellitus the most common
Has been associated with:
Autonomic neuroarthropathy,
Infection (leprosy, HIV),
Toxic exposure (ethanol, drug related),
Rheumatoid arthritis,
Multiple sclerosis,
Congenital neuropathy,
Tabes dorsalis,
Traumatic injury,
Metabolic abnormalities and syringomyelia
5. STAGES OF CHARCOT ARTHROPATHY
(EICHENHOLTZ)
STAGE SIGNS AND
SYMPTOMS
RADIOGRAPHS
0: Clinical
(prefragmentation)
Acute inflammation Normal radiographs
1: Dissolution
(fragmentation)
Acute inflammation,
swelling,erythema,
warmth
Osteopenia, fragmentation,
joint subluxation or dislocation
2: Coalescence Less inflammation, less
swelling, less erythema
Absorption of bone debris,
sclerosis, fusion of larger
fragments
3. Resolution Resolved erythema,
swelling and warmth;
consolidation of healing
Smoothed bony edges; bony/
fibrous ankylosis, consolidation
of deformity
6.
7. Anatomical classification(Brodsky)
Brodsky Type I (midfoot) naviculocuneiform and
metatarsocuneiform joints(60%)
Type II (hindfoot) subtalar, talonavicular, or
calcaneocuboid joints (30-35%)
Type III :
Type IIIA tibiotalar joint and associated bones
Type IIIB pathologic fracture of the tuberosity of
the calcaneus.
8. IMAGING AND DIAGNOSTIC
LAB : WBC, ESR
IMAGING : Radiographs, Bone scan, Ultrasound , MRI
OTHERS: Synovial biopsy, bone probe
9. TREATMENT
Eichenholtz stage 0 : frequent follow-up
patient education on diabetic foot care
protected weight bearing
Eichenholtz stage I : protected weight bearing with
total contact casting or prefabricated pneumatic brace
Eichenholtz Stage II : Total contact casting, prefabricated
pneumatic brace, Charcot restraint orthotic walker or clamshell
AFO
10.
11.
12. Eichenholtz Stage III
if the foot is if the foot is with osteomyelitis
plantigrade non-plantigrade /
recurrent history
of ulcerations surgical debridement
patient can use or amputation
custom inlay shoes
debridement,
exostectomy,correction,
or fusion with
internal fixation