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Bodyfluids
and
circulation
Dr. Nirav Soni
36 State, National, and International Awards Winner
Terms
• Haematology :-
• Angiology:-
• Angiography:-
• Angioplasty:-
• Hemopoiesis:-
• Erythropoiesis:-
• Leukopoiesis:-
• Thrombopoiesis:-
• Erythroblast:-
• Leukoblast:-
• Megakaryoblast/Thromboblast:-
Arteries:- Its bright red in color
Veins:- Dark red in colour
Terms
• Haematocrit:- Weight in (kg) * 8 %
• Blood pH is about 7.2-7.4 (Slightly Alkaline /Basic)
• Total volume of blood is about 5-6 Ltr.
Blood formation from Hemopoietic tissue
Yolk
sac
Liver
Red
bone
marrow
Long
bone
marrow
How to separate blood elements :- ____________________
Process of blood plasma separation
Formation
of WBC
Description about RBCs:- ________
• Enucleated
• Loss of organelle
• High CA
• Round shape and Biconcave
surface
• No mitochondria present
• Life span :- 120 Days/4 Months
Are we millioner?
Yes
Because we are having
Male :- 5-5.5 million/mm3
Female :- 4-4.5 million/mm3
Diseases related to RBCs
• Polycyhtemia/Anemia
• Erythrocytopenia
RBC affinity
Oxyhaemoglobin
Carbaminohaemoglobin
Carboxyhaemoglobin
(toxic)
Maturation of RBCs by Vitamin B12 and folic acids
Spleen
• Graveyard of RBCs
• Blood Bank
Blood = Plasma + RBC + WBC +Platelets
Serum = Blood –Clotting factor
Multilobed Bilobed
“S”
Shaped
PMNL
Eosin dye
gives red
colour
Methylene
blue gives
blue colour
Largest WBC
Kidney
shaped
Smallest
WBC
Fused
together and
from
Macrophages
Descending order :- N > L > M > A > B
Basophil
Heparin
Anti-Coagulans
Histamine
Allergic response
Serotonin
Anti-inflammatory
and vasoconstriction
functions
Abnormal
condition
leukopenia
Leukaemia
(Blood Cancer)
Thrombocytes/Platelets/Megakaryocytes
1.5 -3 Lakh/mm3
Abnormal
condition
Thrombocythemia
Thrombocytopenia
Coagulating Agent Anti-Coagulating Agent
All 13 factors Heparin
Vitamin K
(Menadione/Phyloquinone)
Hirudin
Calcium (IV) Streptokinase
Urokinase
Aspirin (Acetyl Salicylic Acid)
warfarin (also called
Coumadin
Chapter-18 Body fluids and circulation

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