This chapter discusses preterm and postterm newborns. It begins by defining preterm as less than 38 weeks gestation and outlines some of the risks associated with preterm birth such as higher rates of death and birth defects. Some of the problems that can occur with preterm birth are then discussed in more detail, including respiratory distress syndrome, apnea, sepsis and hypothermia. Nursing care is also outlined for various problems including monitoring vital signs, minimal handling and maintaining warmth for thermoregulation.