This document provides an overview of the early history of Cerner, one of the largest healthcare IT companies. It describes how Neal Patterson, Cliff Illig, and Paul Gorup met at Arthur Andersen and founded PGI Inc. in 1979. As consultants at Arthur Andersen, they gained experience in healthcare IT. Their first clients included hospitals in Oklahoma, Missouri, Kansas. They found success developing clinical systems, renaming their company Cerner in 1979. The document profiles the founders and how their experience led them to start a company in healthcare IT.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
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3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
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2. 2nd of Today’s Leading HIS Vendors
• We continue the HIS-tory of today’s vendors with
Cerner, whose 2012 HIT annual revenue of $2.6B
puts them in a solid 2nd place among HIS vendors:
1. $3.2B = McKesson, née HBOC = Walt Huff, Bruce Barrington, & David Owens
2. $2.6B = Cerner, still run by Neal Patterson, co-founded by Cliff Illig & Paul Gorup
3. $1.8B (est) = Siemens, née SMS: Jim Macaleer, Harvey Wilson & Clyde Hyde
4. $1.5B = Epic. Gee, I have to wonder, just who was it who founded them?
5. $1.4B = Allscripts, née Eclipsys, also founded by Harvey Wilson of SMS.
6. $850M (est) - GE Healthcare, née IDX/PHAMIS: created by Malcolm Gleser
7. $597M = Meditech, still run after all these years by Antonino Papallardo
8. $375M = NextGen: née Quality Systems Inc. founded by Sheldon Razin
9. $183M = CPSI, founded by M. Kenny Muscat & Denny P. Wilkins (who??)
10. $156M = HMS (Healthcare Management Systems), Tom Givens & John Doss
11. $150M = Keane, parent giant by John Keane, but HIS div. built by Ray Paris
12. $106M = QuadraMed, née Compucare, founded by Sheldon Dorenfest
13. $75M (est) = Healthland, formerly Dairyland, founded by Steve Klick
3. Three Founders
• I must confess I never knew Neal
Patterson (center) and Cliff Illig
(right) had a third partner when they
founded Cerner: Paul Gorup (left).
• Another interesting pattern in our strange industry: apparently it
takes three to tango when it comes to the top three HIS vendors:
- #1 HBO = Walt Huff, Bruce Barrington and David Owens
- #3 SMS = Jim Macaleer, Harvey Wilson and Clyde Hyde
• And I must start with a sincere thank you to Neal for taking time
form his world-wide travels to introduce me to April Martin who
fully lived up to this email billing, providing many Cerner details:
“Vince .. I bet we can come with some old stuff .. April Martin
is brilliant and will help u .. my travel is taking me afar ..
connect in a couple of weeks .. good luck.”
4. PGI, Inc. in 1979
• No, not the “PGI” you can Google today in Kansas City that makes
iPhone apps, but rather Patterson, Gorup and Illig’s initials, which
they used for the first 4 years as the firm’s name back in 1979.
– (good thing Gorup came before Illig – check that acronym!)
– ((and I must give credit to Neal for that insider joke…))
• These three entrepreneurs met at Arthur Andersen, the giant
accounting/consulting firm of the days of the “Big Eight” (check
out episode #33 at hispros.com for the story of HIS consulting
firms). Arthur was renowned for hiring only the “best & brightest”
among young college graduates, then training them in the AA way
at their St. Charles training facility in IL.
• We’ll look at each of their individual
backgrounds in turn to see what
education & family backgrounds
prepped them for entrepreneurship.
5. Neal Patterson
• From an article in the Kansas City Star, here’s Neal’s early story in own words:
“I was born in Anthony, Kansas, a small town near the Oklahoma-Kansas
border, at the dawn of a new decade—1950, to be precise. The middle of three
brothers, I grew up on a farm near Manchester, Oklahoma. My beginnings
were pretty humble, but full of lessons. My father and mother were tenant
farmers. My family’s water was hand-pumped out of a cistern designed to
catch the rainwater off the roof. Our “bathroom” was located on a path
outside the house—a real issue in winter. The only source of heat was a
propane furnace in the living room, which was a popular place when you
returned from the outhouse. Our household phone line was a party line with
our neighbors on the west side of town. We were a long and a short (ring); if
you needed to call the other side of the highway, our neighbor Mabel had to
connect you through the operator console “patch panel” in her home. I
remember going to our uncle’s house to see my first color TV. Each time a new
technology was acquired that created value in our lives, it was exciting and
noteworthy. I was impatient to see more. Perhaps that was the genesis of my
interest in technology. I am still a fan of the “next new.”
6. Education, Nam, and First Jobs
• “My first business was Patterson Brothers, where we raised hogs to finance our
college education. My younger brother, Bryan Patterson, received his B.S. in
Business Administration and became my father’s trusted partner and
successor, continuing to grow the family farm.
• I received my undergraduate finance degree from Oklahoma State University in
1971, and my MBA in 1972. While an undergrad, I served as chapter treasurer
of Pi Kappa Alpha fraternity... the Vietnam War was at its peak, and on
December 1, 1969, I learned as I watched on a TV in a Stillwater laundromat
how external events shape our lives. The draft was reinstated using a lottery
system, awarding me with a very low draft number. My service was through
the National Guard, as I did my basic training, and I came back for an MBA
before starting my career.
• After completing my MBA, I took a job in Kansas City with Arthur Andersen as
an information system consultant. This was in the Administrative Services
division, which later became Andersen Consulting and then Accenture, the
global management consulting, technology services and outsourcing company.
At Andersen, I met Paul Gorup and Cliff Illig, fellow twenty-somethings who
would later become my business partners.”
7. Cliff & Paul’s Roots
• Thanks again to April Martin for inside stories about early days:
– “Cliff and Neal are both Eagle Scouts. Neal was the youngest Eagle Scout in
Oklahoma at one time – which he attributes to his blind, diabetic scout
master. Cliff’s first entrepreneurial foray was selling T-shirts at scout camp.”
• Cliff Illig - graduated from the University of Kansas School of
Business in 1972 with a degree in accounting and business
administration. He was a system consultant and manager with
Arthur Andersen in Kansas City, Mo. He is Cerner’s vice-chairman
today, and on the Executive Committee of Boy Scouts of America
• Paul Gorup – got his BA in math at Kansas University, and MBA
from Dartmouth College. He left Cerner from 1987 to 1999, but
returned and is VP of Applications and Data Centers today.
– In another cute inside story that April shared, Paul was the
only one of the founding troika to pass the CPA exam at AA. No
wonder they started in the clinical side of HIS systems!
8. Early Days – First Clients
• After spending about 6 years at AA, Neal left to form his own
application software company on 9/4/1979. He sold more in that
first week than he could do alone, and so later that week, Cliff
and Paul met around his dining room table on 9/11 to form PGI.
• The 3 started selling to and working for a variety of industries:
– Paul started working with Cook Paint and H&R Block;
– Cliff was working with manufacturing and trucking firms;
– Neal worked with a healthcare client: MAWD Laboratories.
• Sound familiar? Many HIS start-ups first diversified:
- Steve Klick started out as an DP auditor before
forming Dairyland as a consulting & payroll firm.
- John Doss worked at Ernst & Whinney prior to
forming HMS to write software for NCR minis.
- Another Neal’s (Pappalardo) early client was the
New York City Criminal Justice Department!
9. Finding a Home in Healthcare
• Neal & Co. soon found their niche at 4 nearby hospitals:
– St. John Medical Center (Tulsa, OK) signed as the first
development partner with PGI, followed by
– North Kansas City Hospital (North Kansas City, MO),
– Saint John Hospital (Leavenworth, KS) and
– Research Medical Center (Kansas City, MO).
They pioneered the development of PGI’s PathNet.
• What’s a “PathNet?” In the next
episode, we’ll step back in time a
bit to put both the HIS and LIS
industries into a bit of perspective
to appreciate why PGI entered this
highly specialized field, and how
they rapidly grew to dominate it
under their new name of Cerner.