Cells are the basic structural and functional units of all living organisms. There are two main types of cells - prokaryotic cells, which lack a nucleus, and eukaryotic cells, which have a nucleus surrounded by a nuclear envelope. The plasma membrane surrounds the cell and acts as a selectively permeable barrier that regulates what enters and exits the cell. Transport across the membrane can occur through passive diffusion, facilitated diffusion, or active transport processes that require energy. Vesicle transport is also used to move materials within and between cells.
the presentation gives the structure, function, and electron microscopic image of the various cytoplasmic organelles. it also includes the clinical significance of various organelle damage.
This PowerPoint, designed by East Stroudsburg University student Kristen O'Connor, is a PowerPoint designed for middle school science students on cell organelles.
the presentation gives the structure, function, and electron microscopic image of the various cytoplasmic organelles. it also includes the clinical significance of various organelle damage.
This PowerPoint, designed by East Stroudsburg University student Kristen O'Connor, is a PowerPoint designed for middle school science students on cell organelles.
Coagulation: In medicine, the clotting of blood. The process by which the blood clots to form solid masses, or clots.
More than 30 types of cells and substances in blood affect clotting. The process is initiated by blood platelets. Platelets produce a substance that combines with calcium ions in the blood to form thromboplastin, which in turn converts the protein prothrombin into thrombin in a complex series of reactions. Thrombin, a proteolytic enzyme, converts fibrinogen, a protein substance, into fibrin, an insoluble protein that forms an intricate network of minute threadlike structures called fibrils and causes the blood plasma to gel. The blood cells and plasma are enmeshed in the network of fibrils to form the clot.
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The cell is the structural and functional unit of the body. All living beings develop from pre-existing cells. Robert Hooke (1665) discovered the cell. He observed cork cells of a tree bark.
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Biological screening of herbal drugs: Introduction and Need for
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Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
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The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
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The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
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3. Sizes of Living Things
3
Minimum resolution of a LM 2 microns, the size of a small bacterium
LM can magnify effectively to 1,000 times the size of the actual specimen.
http://amazedatbio.wordpress.com/2012/09/17/life-is-cellular/
4. Properties of life
Reproduction :
o sexual : genetic variation, fertilization
o asexual : genetically identical, e.g. sporulation, budding,
regeneration, binary fission
Metabolism : anabolism Vs. catabolism
Growth and Development
Response to environment
Homeostasis : regulated via organ system
Organization : Cell, tissue, organ, organ system, organism
o acellular
o unicellular : bacteria, yeast
o multicellular : plant, animal
4
5. Cell Theory
All organisms are composed of cells
All cells come only from preexisting cells (Rudolf Virchow)
Cells are the smallest structural and functional unit of organisms
Cells carry genetic information in the form of DNA
5
Robert Hooke (1665) Matthias Jacob
Schleiden (1838)
plant
Theodor Schwann
(1839)
animal
Antony van
Leeuwenhoek (1673)
7. Electron microscope
To resolve smaller structures we use EM, which focuses a beam
of electrons through the specimen (TEM) or onto its surface
(SEM)
TEM are used to study the internal ultrastructure of cells.
A TEM aims an electron beam through a thin section of the
specimen.
o The image is focused and magnified by electromagnets.
o To enhance contrast, the thin sections are stained with
atoms of heavy metals.
SEM are useful for studying surface structures.
The SEM has great depth of field, resulting in an image that
seems three-dimensional.
7
9. Prokaryotic and eukaryotic cells
All cells
o surrounded by a plasma membrane.
o have cytosol, containing the organelles.
o contain chromosomes
o have ribosomes
A major difference
o eukaryotic cell: chromosomes are contained in the
nucleus (within a membranous nuclear envelope)
o prokaryotic cell: the DNA is concentrated in the
nucleoid
9
10. A major difference...
Cytoplasm
o All the material within the plasma membrane of a prokaryotic
cell is cytoplasm.
o Within the cytoplasm of a eukaryotic cell is a variety of
membrane-bounded organelles of specialized form and
function.
Eukaryotic cells are generally much bigger than prokaryotic
cells.
o smallest bacteria, mycoplasmas, are 0.1 to 1.0 micron. (most
bacteria: 1-10 microns)
o Eukaryotic cells are typically 10-100 microns in diameter
10
12. 12
Eukaryotic Cells Prokaryotic Cells
“complex” organisms, including all
plants, protists, fungi and animals
“Simple” organisms, including
bacteria and cyanobacteria
Contain nucleus and membrane bound
organelles
Several chromosome
Lack nucleus and other
membrane-encased organelles.
Single chromosome (DNA + non-
histone protein)
Can specialize for certain functions,
multicellular organs and organisms
Usually exist as single, virtually
identical cells
Cellular respiration occur in
mitochondria
Cellular respiration occur in
mesosome (extended membrane)
Ribosome: 40s, 60S Ribosome: 30S, 50S
Photosynthesis occur in chloroplast Photosynthesis occur in
chlorophyll located region
Cell Wall present in Plants & Fungi only Cell Wall
Cyanobacteria (blue-green algae) e.g. Nostoc, Oscillatoria, Anabaena, Spirulina
13. Cells
Cell coat: Cell wall, Cell membrane
Protoplasm
o Nucleus : nuclear membrane, nucleoplasm (chromatin fiber,
nucleolus)
o Cytoplasm
• cytosol
• organelle
– no membrane bounded: ribosome, centriole,
cytoskeleton
– single membrane bounded: ER, Golgi complex,
lysosome, peroxisome, vacuole
– double membrane bounded: mitochondria, chloroplast
13
16. Plasma membrane
Fluid mosaic model
o Phospholipid bilayer acts
more like a fluid than a
liquid
Contains integral and
peripheral proteins
Semi permeable membrane
Like a city border they
surround the cell and are able
to regulate entrance and exit
16
Campbell et al, Biology; 2009.
17. Phospholipid bilayer
polar heads face outward towards the watery environments both inside and
outside the cell
non polar tails face inward away from the watery environment 17
http://alevelnotes.com/content_images/i38_phospholipid.gif
http://online.morainevalley.edu/WebSupported/BIO111-
Gibbons/membra29.jpg
20. Function of membrane protein
Enzyme
Mediate the passage of ions and most biological molecule
Selective traffic of molecule
Control the interactions between cells of multicellular organisms
Serve as sensor (e.g. receptors, signal transductions)
20
Chandar et al, Lippincott’s Illustrated Reviews: Cell and Molecular Biology; 2010.
21. Transport through membrane
Passive transport: need no energy, downhill
o simple diffusion
o facilitated diffusion: channel protein, carrier protein
Active transport: need energy, uphill
o primary active : direct hydrolysis of ATP
o secondary active : symporters, antiporters
Vesicle transport
o endocytosis: receptor mediated, phagocytosis,
pinocytosis
o exocytosis
21