Case presentation of malaria includes patient demographics, chief complaints, past medical and medication history, personal history, physical examination, laboratory investigations, treatment, Adverse drug reactions, disease information includes definition, causative organism and their classification, clinical presentation, pathophysiology, diagnostic tests, anti malarial drugs patient counseling, lifestyle modifications.

1. CASE
PRESENTATON
ON MALARIA
PRESENTED BY
M.DURGAROHITHA
PHARM-DVI YEAR
174T1T0005

2. PATIENT DEMOGRAPHICS
Patient Name : Venkatasai Age : 22yrs
Gender : Male
DOA : 19/7/22 Dept : MMW
CHIEF COMPLAINTS ;
o Headache and nausea feeling - since 3 days.
o Chills with intermittent fever – since 3 days.
o Weakness/tiredness – since 3 days.
PAST MEDICAL HISTORY ;
NILL

3. Personal history:
Diet – veg
Sleep – sleeplessness
Allergies – no
Appetite – normal
Physical examination:
Vitals Day1 Day2 Day3 Day4
Bp(mmHg) 110/70 110/70 110/70 110/70
Spo2(%) 98 98 98 98
Temp(0f) 101 100 99.8 98.6
PR(bpm) 80 83 83 76

4. Laboratory investigation:
Parameter Observed values Normal values
RBC count 3.1mil/cumm 3.8-
5.8mill/cumm
Esinophils 10% 1-6%
Direct serum
bilirubin
0.3mg/dl 0-0.25mg/dl
Indirect serum
bilirubin
0.9mg/dl 0-0.75mg/dl
Total bilirubin 1.2mg/dl 0.1-1.0mg/dl
PLT count
(1-400000
cells/cum)
Day1 day2 Day3 day4
33000 8.Am-35000
7.30pm-
40000
45000
55000
65000
Other investigations
:
RDT
+ve

5. DIAGNOSIS :
MALARIA

6. SOAP NOTES:
 Subjective
Headache and nausea feeling - since 3 days.
Chills with intermittent fever – since 3 days.
Weakness/tiredness – since 3 days.
 Objective
temp-1010f.
platelet count-33000cells/cum.
eosinophils-10%.
 Assessment
based on patient chief complaints and laboratory abnormalities and
RDT test the
patient was diagnosed as ALGID malaria.

7. P-PLANNING DAYS OF TREATMENT
Brand
name
Genric
name
ROA Dose Frequen
cy
1 2 3 4
I.Oframa
x
Ceftriax
one
IV 1gm BD  - - -
I.Oframa
x forty
Ceftriax
one
+sulbact
um
IV 1.5gm BD -   
I.Larinat
e
Artisuna
te
IV 120mg BD    
I.Pacimo
l
Paraceto
mol
IV 100ml OD  - - -
T.Dolo Paraceto
mol
ORAL 650mg TID -   
IVF
ringers
solution
&
normal
- IV - OD  - - -

8.  ceftriaxone
* 3rd generation antibiotic from cephalosporins family.
* selectively and irreversibly inhibits bacterial cellwall synthesis by binding
to transcmdiasis
which are penicillin binding protin.
* PBP is repair mechanism that normaly helps to maintain bacterial cellwall
integrity.
* Uses UTI ,infection of ears , lungs , sorethroat.
 ceftriaxone +sulbactum-
* cettriaxone works by interfering and certain process,that helps the
bacterial to grow and increses in number.
* sulbactum inhibits some chemicals produce by the bacteria and makes
the bacteria more
sensitive to the ceftriaxone activity.
 pantoprazole- PPI(proton pump inhibitor)
* PPI irreversibly binds to the H+/K+ ATPase pump.
then prevent the movement of hydrogen ions from parietal cells into
stomach it results no.
* HCL production it means neutralizes the excess acid.
* Uses prevent ulcers,GERD.
 Artisunate –
antimalarial drug

9. DISEASE INFORMATION
DEFINATION:
Malaria is a mosquito-borne infectious disease that affects humans and
other animals . Mainly it is caused by plasmodium species.
Causative organisms:
P . Vivax, p . Falciparum , p . ovalae , p. malarial, p. knowlesi
Classification:
Algid malaria - p. falciparum - cause hemodynamic
disorders.
Bilious malaria - p.falciparum - affects liver.
Cerebral malaria - p.falciparum - affects cerebrum.
Congenital malaria - p.falciparum/p.vivax - mother via fetal
circulation.
Transfussion malaria - various plasmodium species - introduced by blood
transfusion, needles
sharing.
Qustidian malaria - p.falciparum and p.vivax - recurrent fever every 36
to 48hrs.

11. Signs and symptoms

12. Pathophysiology

13. Diagnostic tests:
 Light microscopy-species identification.
 serology tests-for antibody against malarial parasite.
 RDT- detects specific antigen produced by malarial parasite in blood
of infected individual. some RDT can detect only one species
(p.falciparum) while others detect multiple species.
 PCR – amplification of malaria DNA.
 Immunofluorescence

14. Anti malarial drugs
 Cinchona alkaloids – quinine, quinidine
 Quinoline methanol – mefloquine
 4-aminoquinoline – choloroquine,
piperaquine
 Biguanides - chloroquanides
 8-aminoquinolines – primaquins.tafenoquine
 Sulfonamides and sulfons –
sulfadoxine,sulfamethopyrazine
 Naphihyndine – pyronaridines
 Ivophthoquinom – atovaquaone
 Sesquiturine analogues – arthemether,
artesunate
 Newly antimalarial – arthemisinon,
fosmidomycin

15. PATIENT COUNSELLING
Malaria can often be avoided using abcd approach to prevention.
A : awareness of risk; find out whether your at risk of getting
malaria.
B : bite prevention; avoid mosquito bites by using insect repellants
covering your
arms and legs and using a mosquito nets.
C : check whether you need to take malaria prevention tablets; if
you do make sure
you take the night antimalarial tablets at right dose and finish
the coarse.
D : diagnosis; seek immediately medical advice if you have malaria

16. Life style changes:
 Avoid junk oil ad spicy foods
 Go for long sleeves
 Use insect repellent
 Take vit C and A rich foods such as
popaya, beetroot, other citrous
foods T vit B complex
 Take orange juicies-may helps in
boostimg immunity ,also helpful to
reduce fever.