The document discusses carbon and its various forms and properties. It notes that carbon forms more compounds than any other element except hydrogen. It exists in several allotropes including diamond, graphite, and amorphous forms like coal and coke. The formation of coal from buried plant matter over millions of years is described. Different types of coal are classified based on their carbon content. The process of destructive distillation is outlined which produces gases, ammoniacal liquor, coal tar, and coke from coal.
Mind Blowing Facts About Carbon Atomic Number.pdfChloe Cheney
Do you know what's carbon atomic number, what does c stand for on the periodic table & what element is C in chemistry? Here are facts about carbon atomic number
Carbon belongs to the group IV of the periodic table.
It has four electrons in its outermost orbit, so its valency is four.
Carbon is a non-metal.
Why so many Carbon Compounds in nature
Because carbon is chemically unique.
Only carbon atoms have the ability to combine with themselves to form long chains
The number of carbon compounds is larger than that of all other elements put together.
Occurrence of carbon
The name ‘carbon’ is derived from the Latin
word ‘carbo’ meaning coal. Carbon is found in
nature in free as well as compound state. Carbon in
the free state is found as diamond and graphite, and
in the combined state in the following compounds.
1. As carbon dioxide and in the form of carbonates
such as calcium carbonate, marble, calamine
(ZnCO3)
2. Fossil fuel – coal, petroleum, natural gas
3. Carbonaceous nutrients – carbohydrates,
proteins, fats
4. Natural fibres – cotton, wool, silk
Properties of carbon
Allotropic nature of Carbon
Allotropy - Some elements occur in nature in more than one form. The chemical properties
of these different forms are the same but their physical properties are different. This
property of elements is called allotropy. Like carbon, sulphur and phosphorus also exhibit
allotropy.
Allotropes of carbon
A. Crystalline forms
1. A crystalline form has a regular and definite arrangement of atoms.
2. They have high melting points and boiling points.
3. A crystalline form has a definite geometrical shape, sharp edges and plane surfaces.
Mind Blowing Facts About Carbon Atomic Number.pdfChloe Cheney
Do you know what's carbon atomic number, what does c stand for on the periodic table & what element is C in chemistry? Here are facts about carbon atomic number
Carbon belongs to the group IV of the periodic table.
It has four electrons in its outermost orbit, so its valency is four.
Carbon is a non-metal.
Why so many Carbon Compounds in nature
Because carbon is chemically unique.
Only carbon atoms have the ability to combine with themselves to form long chains
The number of carbon compounds is larger than that of all other elements put together.
Occurrence of carbon
The name ‘carbon’ is derived from the Latin
word ‘carbo’ meaning coal. Carbon is found in
nature in free as well as compound state. Carbon in
the free state is found as diamond and graphite, and
in the combined state in the following compounds.
1. As carbon dioxide and in the form of carbonates
such as calcium carbonate, marble, calamine
(ZnCO3)
2. Fossil fuel – coal, petroleum, natural gas
3. Carbonaceous nutrients – carbohydrates,
proteins, fats
4. Natural fibres – cotton, wool, silk
Properties of carbon
Allotropic nature of Carbon
Allotropy - Some elements occur in nature in more than one form. The chemical properties
of these different forms are the same but their physical properties are different. This
property of elements is called allotropy. Like carbon, sulphur and phosphorus also exhibit
allotropy.
Allotropes of carbon
A. Crystalline forms
1. A crystalline form has a regular and definite arrangement of atoms.
2. They have high melting points and boiling points.
3. A crystalline form has a definite geometrical shape, sharp edges and plane surfaces.
Carbon is one of the most important non-metallic element.
Antoine Lavoisier named carbon from the Latin word ‘Carbo’ meaning coal.
Carbon is present in our muscles, bones, organs and other components of living matter.
Thus, Carbon Chemistry is also called as Living Chemistry.
Carbon is one of the most important non-metallic element.
Antoine Lavoisier named carbon from the Latin word ‘Carbo’ meaning coal.
Carbon is present in our muscles, bones, organs and other components of living matter.
Thus, Carbon Chemistry is also called as Living Chemistry.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
2. Describe all you know about carbon.
Hey you! Yes you!
What do you know
about
CARBON?
3. • Carbon can be referred to as unique based on the following facts:
Fact 1
Carbon forms the
largest number of
compounds, next
only to hydrogen.
Fact 2
Carbon ranks
seventeenth in
the order of
abundance in
the earth’s crust
Fact 3
Carbon occurs
in the free
native state as
well as in the
combined state.
Fact 4
Carbon and its
compounds are
widely
distributed in
nature.
In Fact 3, two terms are in colour, what do you understand by those terms?
4. ACTIVITY
Fact 5
In its elemental
form, carbon
occurs in nature
as diamond and
graphite
Fact 6
Coal, charcoal
and coke are
impure forms of
carbon.
Fact 7
In the combined state,
carbon is present as
carbonate in many
mineral and also as
hydrocarbons in
natural gas, petroleum
1. Discuss in group, your understanding of the statements in step 5-6
2. In what other aspect of your life do you use carbon?
3. Carbon belongs to what group and period in the periodic table.
4. From your answer in question 3, deduce if carbon is a metal or a non metal and give
your reason.
5. • Carbon can be referred to as unique based on the following facts:
Fact 8
Nearly the worlds
energy is obtained
by burning carbon
and its
compounds.
Fact 9
It is the main element
that occurs in many
products of chemical
industries. Products
like plastics, tyres,
detergents, soap,
cosmetics etc.
Fact 10
Carbon is an
essential element
in living systems.
The food we eat
daily contain
carbon.
Fact 11
Carbon and its
compounds are
widely
distributed in
nature.
6. Atomic Structure of Carbon
• The atomic number of carbon is
6
• The shell electronic configuration of
carbon is
2, 4
• Carbon belong to group 4 and period
2 on the periodic table
7.
8.
9. Allotropes of Carbon
The existence of one element in different forms, having different
physical properties, but similar chemical properties is known as
allotropy. Different forms of an element are called ‘allotropes’ or
allotropic forms. Carbon shows allotropy.
The various allotropic forms of carbon can be broadly classified into
two classes.
1. Crystalline form
2. Amorphous form
13. Amorphous Forms of Carbon (COAL)
1. How does coal come to exist?
2. How is it coal obtained?
3. What are the uses of coal?
14. Formation of Coal
• It takes millions of years for coal to
form.
• Millions of years ago, there were
places on the earth with dense forests
in wetlands, due to natural calamities
such as flooding, tsunami, landslide,
etc. these forests got buried under the
soil. Over the years, more and more
soil compiled over these forests.
• This traps the carbon that was buried
in the sediments. Carbonization takes
place, carbonization is a process
where vegetation turns into carbon. It is
a slow process.
15.
16. Types of Coal
Peat – Like coal which is about 60%
carbon by mass
Lignite – Which is a brown soft coal
having about 67% carbon by mass
Sub-Bituminous –It contains about 70%
by mass of carbon
Bituminous –It contains about 88% by
mass of carbon
Anthracite – This is tough and hard,
having about 94% of carbon by mass
17. Destructive Distillation of Coal
• Coal is a complex mixture of compounds composed mainly of carbon,
hydrogen and oxygen with small amount of nitrogen, sulphur, phosphorus and
impurities. A wide variety of substances can be obtained from it by a process
known as destructive distillation of coal.
The chief and important products of this process are:
1. Coal gas
2. Ammoniacal liquor
3. Coal tar
4. Coke