The document provides a frame-by-frame summary of the opening sequence of the film "Cape Fear". It establishes the gloomy and ominous tone set in the opening credits with a subverted studio logo underwater. The sequence then introduces a young, innocent girl who speaks positively about Cape Fear before ominous music plays over shots of the convict, Robert De Niro's character, working out in his cell and being released from prison with an intent expression. The summary suggests the convict immediately sets off with an unknown purpose upon his release as the sky darkens, leaving the audience feeling afraid and uncertain of what he has planned.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
The hemodynamic and autonomic determinants of elevated blood pressure in obes...
Cape fear 9 frame analys coope ris
1. Cape Fear 1991 Martin Scorsese Starring: Robert De Niro, Nick Nolte & Jessica Lange
2. Frame 1 The movie opens with a Universal ident. However, the image is subverted and presented in a gloomy blue colour. The image also appears as if underwater. This links to a prominent location in the movie. The sound of falling rain in the background adds to the gloomy atmosphere of the initial shot
3. Frame 2 Although this shot is taken from the title sequence it still helps to develop the atmosphere of dread in the opening sequence. The reflection of a shadowy and menacing figure is presented atop a backdrop of calm, lightly rippling water. This juxtaposition of the calm with the violent lies at the core of the movie.
4. Frame 3 The camera slowly zooms out, stopping at a mid-shot of a girl in her late teens/early twenties. She is the archetypal victim of the genre. The girl is dressed in white carrying connotations of innocence and purity. The dialogue speaks of the enjoyment the young girl has experienced in a “magical” place, the inaptly named “Cape Fear” This scene creates uncertainty in the viewer as its overwhelmingly positive tone is a marked contrast to what is to come.
5. Frame 4 The movie opens with an establishing shot showing Cady’s prison cell. Cady’s wall is covered in pictures of historical figures, martyrs and super heroes. The choice of images suggests he respects absolute power & aggression and feels that he has been mistreated. The camera gradually zooms out to reveal the scope of his obsession. The clip features bombastic, gloomy orchestral Music creating a sense of foreboding/ anticipation of bad things to come
6. Frame 5 Focus on the convict working out. The movie shows the audience that this man is a powerful person who they should be afraid of due to him working out Scales on back imply that he feels that he needs to deal out what is right and what is wrong, he is interested in truth and justice. The audience do not know who this person is creating tension and fear from them. The audience feel edgy as it is not showing the convict’s face. In the foreground of the shot is the bars which give a sense of safety to the audience but may also give them a nervy feeling because he is behind the bars.
7. Frame 6 Convict is being let out of the prison creating the fear in the audience and the mystery into what they think he is going to do now that he is free. The face of the convict is now revealed. This relieves some of the fear from the audience as they now know what he looks like reducing the mystery that is shrouded around him. In the background of the cell there is old books which is revealed as being law books. This shows to the audience that he is a knowledgeable person and has been working towards something by reading these law books. In this shot the guards are quite polite to the convict and reveal his name suggesting to the audience that he is well known in the prison maybe implying that he has been there a long time. Also when he is walking past the other cells they are quiet suggesting that they fear this man.
8. Frame 7 This shot shows the man leaving the prison with no one waiting for him as the guard asks him if anyone will be waiting for him in which he reply’s no. This suggests that he is not close to anyone which makes the audience create an image of him as a loner and a outcast. A shot of the prison and the guards shows the convict’s freedom. This creates mystery in the audience as to what he is going to do. The long shot is used to show that now he can do what he wants which creates fear and tension in the audience as they wonder what he is going to do. The dark and cloudy sky suggests that something dark is about to occur, giving the audience the time to prepare for this dark moment. The convict walks straight off straight away showing the audience that he is keen to get on with his freedom and suggests that he has some business to attend to.
9. Frame 8 The clouds have gotten bigger and darker since the last shot which links in with the convict steely eyed face which suggests that he is out to do something dark and the audience should be afraid. The convict marches straight up to the camera frightening the audience and creating fear for them. It also intimidates the audience as he means business. The expression on the character’s face is a small smirk suggesting to the audience that he is not a usual person and that he is out to do what he needs to do. The extreme close up on the convict’s face is used to intimidate the audience and create fear among the audience.
10. Frame 9 Shot of a lavish house giving the audience the thought that this is the convict’s home or that the convict is going to this house to deal with his business. The shot is from around the bushes suggesting to the audience that the shot is from the convict’s point of view suggesting that he is watching this house. House is a contrast to the convict as the house is bright and colorful where as the convict is more gray and dull. The sky is also bright and colorful suggesting that this is not the convict’s house.