Praharshit Sharma is a bioinformatician currently working as a project fellow at CSIR-Centre for Cellular and Molecular Biology in Hyderabad, India studying microRNA-mRNA interactions in neurodegenerative diseases. He has work experience in bioinformatics industrial training and research internships. Praharshit has an MSc in Bioinformatics and PG Diploma in Bioinformatics. He has skills in Linux, programming languages, bioinformatics tools and databases. Praharshit has publications and presentations in bioinformatics and has done statistical analysis projects correlating genetic code, protein structure and crystallographic data.

1. Curriculum Vitae
PERSONAL INFORMATION Praharshit Sharma
S-112, CSIR-CCMB, Uppal Road, 500007 Hyderabad (India)
+91 8143 647 944 +91 40 2719 2745
praharshit.sharma@gmail.com
Skype praharshit.sharma
PERSONAL STATEMENT A creative Bioinformatician seeking innovative roles in the field.
WORK EXPERIENCE
21/04/2014–Present Bioinformatics Project Fellow
CSIR-Centre for Cellular and Molecular Biology, Hyderabad (India)
microRNA-mRNA interactomics in neuro-degenerative diseases such as Schizophrenia.
18/10/2013–17/04/2014 Bioinformatics Industrial Trainee
BioServe Biotechnologies (India) Pvt Ltd, Hyderabad (India)
NGS data analysis (Differential Gene Expression of Rice Transcriptome and Variant Analysis of E.coli
DH10B strain).
04/07/2010–13/12/2010 Research Intern
CSIR-Indian Institute of Chemical Technology, Hyderabad (India)
Study of Heterogeneous Catalysis employing Heteropolyacids.
22/05/2008–15/07/2008 Summer Intern
SAIL-Steel Authority of India Limited, Bhadravati, Shimoga (India)
Spectroscopic analysis of alloying elements, gases in steel and time-management in the laboratory.
EDUCATION AND TRAINING
01/08/2012–17/08/2013 MSc Bioinformatics
Sikkim Manipal University, Manipal (India)
Bioinformatics, Computer Programming and Computational Biology.
01/08/2011–31/07/2012 PG Diploma Bioinformatics
Institute of Bioinformatics and Applied Biotechnology, Bangalore (India)
Bioinformatics, Biomathematics, Biostatistics
01/08/2005–29/07/2011 Integrated MSc (Hons) Chemistry
Birla Institute of Technology and Science, Pilani (India)
Physical, Inorganic, Organic, Analytical and Computational Chemistry
PERSONAL SKILLS
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2. Curriculum Vitae Praharshit Sharma
Mother tongue(s) Telugu, Tamil
Other language(s) UNDERSTANDING SPEAKING WRITING
Listening Reading Spoken interaction Spoken production
English C2 C2 C1 C1 C2
Merit Certificate in English CORE from CBSE, New Delhi
Hindi B2 B2 B2 B2 B2
AISSE-2003 from CBSE, New Delhi
Levels:A1/A2: Basic user - B1/B2: Independent user - C1/C2: Proficient user
Common European Framework of Reference for Languages
Communication skills Excellent negotiation skills as a past coordinator of Project BITS Embryo which complements on-
campus education at BITS Pilani through scheduled online video-conferenced lectures delivered by its
Alumni and/or friends spread worldwide.
Organisational / managerial skills Certified Documentation skills as a past coordinator of NSS (National Service Scheme) - BITS Pilani
Chapter, a Government of India initiative.
Job-related skills NGS data analysis.
Sequence analysis.
Knowledge of installation and usage of allied Bioinformatic tools and software.
Familiarity with various Bioinformatics databases.
Computer skills Linux, C, C++, MySQL, PHP, Java, PERL, Python and R/ Bioconductor.
Other skills Scripting in Mathematica ver.10
ADDITIONAL INFORMATION
Publications A mathematical model of central dogma of molecular biology employing a novel irrational-integral-
imaginary (i3) encoding and numerical approximation based on cellular automaton. Praharshit
Sharma, Bhupendra Kumar Pathak, Tiratha Raj Singh. International Journal for Computational
Biology. Vol. 3, No. 1 (2014) pp. 27-30.
Proof of Achimowicz's result in relation to Genetic Code through a Cellular Automaton Approach.
www.academia.edu/5536744
Justification of Achimowicz's result for Genetic codon length in the specific case of Mitochondrial DNA
by using Combinatorics. www.academia.edu/6156747
Presentations Plausible explanation of anfinsens dogma by treating disulfide bond-distances as radii of 3-
dimensional von-neumann cellular automata (CA) for small globular proteins. 2nd International
Symposium on Protein Folding and Dynamics, 5-7 Nov, 2014. F1000Posters 2014, 5: 1837
30-offset elementary cellular automata rule degeneracies pertaining to exact correlation of first six first
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3. Curriculum Vitae Praharshit Sharma
differences of number of black cells in nth-generation with m/z peak differences of characteristic
compounds. Brainstorming Meeting and Workshop on Proteomics: Present and Future, 22 - 24 Nov
2014. F1000Posters 2014, 5: 1884
Modeling host [pattern recognition receptors] vs. pathogen [associated molecular patterns]
interactions using parametric complimentarily-incremented docking (PCID)-“3DVNBNNCA” as a
hypothetical study. International Conference on Host Pathogen Interactions (ICHPI), 12 - 15 Jul 2014.
F1000Posters 2014, 5: 958
Ab-initio reconstruction of genetic code, prediction of Tm
, C-value paradox and correlation with
ANISOU data based on cellular automaton theory with further applications to protein secondary
structure prediction, codon-bias and degeneracy. National Conference on "New Trends in
Bioinformatics" Theme: New Methods, Softwares, Databases, Web-tools of Bioinformatics from India,
30 - 31 Jul 2012. F1000Posters 2013, 4: 1315
Bioinformatics database design: an effective method for the universal indexing of DNA sequences
using quaternary logic tables for efficient data mining. 3rd Annual Biotechnology Conference for
Students (ABCS), 12 - 13 Nov 2011. F1000Posters 2013, 4: 1314
Projects Statistical constraint on ANISOU data from RCSB-PDB that correlates significantly with:
# The outcome of mRNA Codon length approximation to Achimowicz's result pertaining to Genetic
translation [PMID: 7280057]
# The minimal Oligonucleotide Melting Temperature (predicted vs. observed) as validated by 475
PCR assays [PMID: 11673362]
# The absolute difference between Eigenvalues for the folding sequence of small Globular proteins
obtained through minimal model calculations [PMCID: PMC2286534] # The 'significand' of duration of
Kali-Yuga with exponent adjusted to same as that of universal-standard-scaling-factor of ANISOU =
10000 [ISBN: 978-8185208039]
References Dr. Prashanth Suravajhala: PhD,Founder, Bioclues.org and Director, Bioinformatics.org Address:
Bakkegården 6, 2TH, 4000, Roskilde, Denmark Phone: +45 71495160 Email: prash@ruc.dk
prash@bioinformatics.org
Dr. Inamul Hasan Madar, MSc, M.Phil, PGDCA, DMLT, ADMD, PhD.
Research Doctorate Fellow, Laboratory of Gaseous Ion Chemistry
Korea University, Seoul, South Korea Web: ionchem.korea.ac.kr Mobile: +82-10-6873-0485 Email:
inambioinfo@korea.ac.kr
inam@compcyc.org
Ms. Gadicherla Ramya, Laboratory Manager, BioServe Biotechnologies (India) Pvt. Ltd. # 3-1-135/1A,
CNR Complex, Genome valley, Mallapur Main Road, R.R.Dist, Hyderabad - 500 076 Phone: +91-40-
27178176, Fax: +91-40-27178178
Email: ramya@bioserve.com
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