Burn is coagulative necrosis of the skin’s tissues, usually caused by excessive heat
Excess heat causes rapid protein denaturation and cell damage
Wet heat (scald) travels more rapidly into tissue than dry heat (flame)
A surface temperature of over 60˚C produces immediate cell death as well as vessel thrombosis
The dead skin tissue is known as Eschar
Introduction
Burns
Clinically Relevant Anatomy Of Hand
Common Hand Problems In Burns
Surgical Management
Evidence based Physical Therapy Rehabilitation
Outcome Measures
Summary
References
Burn is coagulative necrosis of the skin’s tissues, usually caused by excessive heat
Excess heat causes rapid protein denaturation and cell damage
Wet heat (scald) travels more rapidly into tissue than dry heat (flame)
A surface temperature of over 60˚C produces immediate cell death as well as vessel thrombosis
The dead skin tissue is known as Eschar
Introduction
Burns
Clinically Relevant Anatomy Of Hand
Common Hand Problems In Burns
Surgical Management
Evidence based Physical Therapy Rehabilitation
Outcome Measures
Summary
References
Physiotherapy rehabilitation of burns with various forms of exercise, modalities, recent advances, splints. all the therapies described here are evidence based practices with references
Physiotherapy rehabilitation of burns with various forms of exercise, modalities, recent advances, splints. all the therapies described here are evidence based practices with references
A complete review for all medical students and doctors working in burn unit in any hospital. #Emergency #BurnProtocol #protocol #Burns #Abhishek #MUSTKNOW #knowledge #Medical #Health
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
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Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. • Neurologic- delirium, seizure, peripheral nerve injury
• Psychiatric-PTSD, Anxiety,
• Genitourinary- early acute renal failure, late renal failure
• Endocrine – acute adrenal insufficiency
• Cardiovascular-endocarditis, suppurative thrombophlebitis
• Pulmonary- pneumonia, respiratory failure, CO intoxication
• Hematologic –neutropenia, thrombocytopenia, DIC
• Otolaryngologic-auricular chondritis, sinusitis, otitis media
• Enteric – gastroduodenal ulcer, pancreatitis, hepatic dysfunction
• Ophthalmologic- ectropion,
• Musculoskeletal – heterotrophic scar, heterotopic ossification ,
marjolins ulcer
Almost every system may involve
3. Burn shock
• 3 types of shock can
affect burn victim
1. neurogenic shock –due
to severe pain
• Treatment – pain killers
(IV morphine)
2. hypovolemic shock- due
to fluid loss
• Treatment- fluid
resuscitation
4. 3. septic shock -due to infections
• Treatment –iv antibiotics, oxygen and
fluid
• 50-to-60 % of burn injury deaths
• develop after
• infection of the burn wound
(Pseudomonas aeruginosa)
• pneumonia from breathing tubes
• UTI from bladder catheters
• Management-IV antibiotics , oxygen
and IV fluids with careful
monitoring
5. Burn scarring
• unavoidable complication of burn
• prevalence -32 to 72 % of burn patient
• In 3rd and 4th degree –more severe and lifelong
• Formation depends on size, depth, patients gene,
age, ethnicity etc
• 3 types
• Keloid
• Hypertrophic scar
• Scar contracture
6. Keloid scar
• thicker type of burn scar
that grow beyond the
burned area
• the result of an overgrowth
of scar tissue
• pink to red in colour
• Management-steroid
injection, excision, laser
therapy
7. Hypertrophic scar
• Hypertrophic scars are confined to the
site of the injury
• typically appear red and raised
• Mechanism- strong expression of
• tumor growth factor beta(TGHB)
• focal adhesion kinase 1 (FAK1)
• Treatment-steroid injections,
revision excision with grafting,
laser therapy
• Prevention- pressure garments,
local tissue rearrangement,
physical therapy
8. Contractures
• Abnormal shortening of tissue (muscle) resulting
in resistance of that to stretching
• Common sites- joints, eyelids, cheeks, lips, neck,
elbow, knee etc.
• It can be
• Extrinsic- pull during healing phase
• Intrinsic- loss of tissue (fibrosis)
• Treatment -Release of contracture surgically,
antihistaminic for itching
• Prevention -Physical and Occupational
therapy, Pressure garments, Topical silicon
sheeting, tissue expansion
10. Marjolin's ulcer
• Very well differentiated squamous cell
carcinoma occurring in scar ulcer
• Locally malignant
• No spread to regional lymph nodes
• Painless
• Treatment –wide excision with at
least 2cm margin
• Radiotherapy is contraindicated
12. Posioning and splinting
• Starts in the intensive care unit to prevent contracture
• The basic rule - maintaining the body part in opposite plane and
direction which it will potentially contracture (anti contracture position)
The fetal position (flexed) is position of comfort so anti
contracture position is of extension.
13. Physical
Therapy
• Gross motor skills
• Focus on lower
extremities
• Feet
• Knees
• Hips
Getting in and out of bed
Walking
Going up and down stairs
Occupational
Therapy
• Focus on upper extremities
• Arm
• Hands
• fingers
• Focus on activities of daily living
• Feeding
• Dressing
• Getting out of bed
• Going to the bathroom
15. Scar management
• Tension release with incision- defect created is
treated with grafting such as FTSG ,STSG
• Tension release with tissue rearrangement –Z-
plasty
• Intralesional corticosteroid injection-
suppress inflammatory process of wound
,decrease collagen synthesis and increase
collagen degradation
• Cryotherapy –increases vascular damage
leading to necrosis of scar tissue
• Fat grafting into scar- recent study
• Scar massage
• Laser based therapies
• Pulse dye laser (PDL)
• Ablative CO2 laser
16. Laser based therapies
1. 585 nm pulse dye laser (PDL)
• Excellent therapeutic measure for younger
hypertrophic scar
• Induces dissociation of disulfide bond in
collagen fibers and causes realignment and
decrease fibroblast proliferation
• Repeated treatment (2 to 6)is required for better
outcome
• Side effects – erythema/purpura for 7 to 14
days, hyperpigmentation or hypopigmentation
17. 2. Ablative CO2 laser (10600nm)
• Targets water in underlying tissue
• It has greater potential depth of treatment (4mm
compared to 1.8 mm in non ablative laser)
• Works by ablating microscopic column of tissue to
flatten scars and is also believed to stimulate
matrix metalloproteinase and other signaling
pathways to collagen reorganization
• Only a portion is treated with column of energy to
create targeted area of thermal damage
(microthermal treatment zone)
• The untreated area act as reservoir of collagen and
tissue regrowth
18. Psychological therapy
• Major psychological problems
• Depression
• post traumatic stress disorder
• concerns about image
• anxiety about returning to society
• nightmares and flashbacks associated
with incident of burn
• Psychological distress occurs in as many
as 34% of burn patients and persists in
severity long after discharge
• Help the patient to develop positive mental
state
19. • Method
• Combines drug therapy and cognitive
behavioral therapy
• Beginning of therapy
• as soon as the patient is able to
understand the situation
• Goal of therapy
• To help the patient recognize thinking
that may differ physical and emotional
recovery from burn in order to return to
independent lifestyle
20. Early Burn reconstruction
• Small set of operations required in the first few year of injury
• collaboratively with the patient family and the patient's therapists
• Do not rush into these
• A balance must be drawn between repeat trauma of surgery and
patients functional and cosmetic needs
• Common procedures-
• Head and neck- lid release, neck release
• Hand- dorsal hand release, web space release
• Upper extremity- heterotopic ossification removal, axillary
contracture release
• Lower extremities- dorsal foot release, popliteal release, hip
release