Liquid crystal LC is the substances that flow like liquids but maintain some of the ordered structure characteristics of liquid crystals. Examined and summarized the types of liquid crystals. Analyzed the structural characteristic of smectic, nematic and cholesteric liquid crystals. It is noted that cholesteric liquid crystals are helically twisted structure and the pitch of the helix which is temperature dependent and individual chemical properties of liquid -crystalline compounds of cholesterol. Results on the influence of temperature on rheological properties of cholesteric liquid crystal are presents. This chapter describes briefly about classification of liquid crystals their structure and properties. the main aim of this review article is to scientifically highlight pharmaceutical liquid crystals, its importance in current development of targeted drug delivery system. Objects of this review is also to provide in depth information of pharmaceutical liquid crystal technology which include advanced technology development. V. Viswanatha | C. Rajaramb | S. R. Fathimac | D. Bhanu priyad "Brief Review of Liquid Crystals" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-6 , October 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18770.pdf
Intermediate state of mesophases & halfway between isotropic liquid &solid crystal.
In solid crystal, basic unit display translational long range order, with center of molecule located on crystal lattice &display orientational order.
In isotropic liquid, basic unit do not preset positional or orientational long rang order.
Liquid Crystals are discovered in 1888 by Austrian botanical physiologist Friedrich Reinitzer. Liquid Crystal (LC) is a state of matter intermediate between that of a solid crystalline and an isotropic liquid. Copy the link given below and paste it in new browser window to get more information on Liquid Crystal:- http://www.transtutors.com/homework-help/mechanical-engineering/liquid-crystal.aspx
Chemistry is a branch of science which deals with the study of matter and all the chemical reactions taking place in a matter.
It also deals about the changes taking place in matter.
Due to concern with different methods and changes, chemistry is divided into 8 branches.
All of these eight branches has been discussed in above slides.
John Dalton was the first who discoered the atomic theory.
examples of materials that have directional properties as a single cry.docxtodd401
examples of materials that have directional properties as a single crystal but are isotropic in their polycrystalline form.
Solution
Liquid crystals (LCs) are matter in a state that has properties between those of conventional liquid and those of solid crystal. [1] For instance, a liquid crystal may flow like a liquid, but its molecules may be oriented in a crystal-like way. There are many different types of liquid-crystal phases, which can be distinguished by their different optical properties (such as birefringence). When viewed under a microscope using a polarized light source, different liquid crystal phases will appear to have distincttextures. The contrasting areas in the textures correspond to domains where the liquid-crystal molecules are oriented in different directions. Within a domain, however, the molecules are well ordered. LC materials may not always be in a liquid-crystal phase (just as water may turn into ice or steam).
Liquid crystals can be divided into thermotropic, lyotropic and metallotropic phases. Thermotropic and lyotropic liquid crystals consist of organic molecules. Thermotropic LCs exhibit a phase transition into the liquid-crystal phase as temperature is changed. Lyotropic LCs exhibit phase transitions as a function of both temperature and concentration of the liquid-crystal molecules in a solvent (typically water). Metallotropic LCs are composed of both organic and inorganic molecules; their liquid-crystal transition depends not only on temperature and concentration, but also on the inorganic-organic composition ratio.
Examples of liquid crystals can be found both in the natural world and in technological applications. Most contemporary electronic displays use liquid crystals. Lyotropic liquid-crystalline phases are abundant in living systems. For example, many proteins and cell membranes are liquid crystals. Other well-known examples of liquid crystals are solutions ofsoap and various related detergents, as well as the tobacco mosaic virus.
.
Intermediate state of mesophases & halfway between isotropic liquid &solid crystal.
In solid crystal, basic unit display translational long range order, with center of molecule located on crystal lattice &display orientational order.
In isotropic liquid, basic unit do not preset positional or orientational long rang order.
Liquid Crystals are discovered in 1888 by Austrian botanical physiologist Friedrich Reinitzer. Liquid Crystal (LC) is a state of matter intermediate between that of a solid crystalline and an isotropic liquid. Copy the link given below and paste it in new browser window to get more information on Liquid Crystal:- http://www.transtutors.com/homework-help/mechanical-engineering/liquid-crystal.aspx
Chemistry is a branch of science which deals with the study of matter and all the chemical reactions taking place in a matter.
It also deals about the changes taking place in matter.
Due to concern with different methods and changes, chemistry is divided into 8 branches.
All of these eight branches has been discussed in above slides.
John Dalton was the first who discoered the atomic theory.
examples of materials that have directional properties as a single cry.docxtodd401
examples of materials that have directional properties as a single crystal but are isotropic in their polycrystalline form.
Solution
Liquid crystals (LCs) are matter in a state that has properties between those of conventional liquid and those of solid crystal. [1] For instance, a liquid crystal may flow like a liquid, but its molecules may be oriented in a crystal-like way. There are many different types of liquid-crystal phases, which can be distinguished by their different optical properties (such as birefringence). When viewed under a microscope using a polarized light source, different liquid crystal phases will appear to have distincttextures. The contrasting areas in the textures correspond to domains where the liquid-crystal molecules are oriented in different directions. Within a domain, however, the molecules are well ordered. LC materials may not always be in a liquid-crystal phase (just as water may turn into ice or steam).
Liquid crystals can be divided into thermotropic, lyotropic and metallotropic phases. Thermotropic and lyotropic liquid crystals consist of organic molecules. Thermotropic LCs exhibit a phase transition into the liquid-crystal phase as temperature is changed. Lyotropic LCs exhibit phase transitions as a function of both temperature and concentration of the liquid-crystal molecules in a solvent (typically water). Metallotropic LCs are composed of both organic and inorganic molecules; their liquid-crystal transition depends not only on temperature and concentration, but also on the inorganic-organic composition ratio.
Examples of liquid crystals can be found both in the natural world and in technological applications. Most contemporary electronic displays use liquid crystals. Lyotropic liquid-crystalline phases are abundant in living systems. For example, many proteins and cell membranes are liquid crystals. Other well-known examples of liquid crystals are solutions ofsoap and various related detergents, as well as the tobacco mosaic virus.
.
Here you can find a simple and short note on Pharmaceutical Preformulation studies.
Reference book:
The theory and practice of industrial pharmacy by Lachman and Lieberman.
If you are in search of the Chemistry book in pdf format for class 9 matric then you are at right page because here we have shared the Punjab Textbook board PTB 9th class Chemistry Book pdf Download or you can read it online below:
.Chemistry 9Th Book, PUNJAB TEXT BOOK
Chemistry 9th Class Book (English Medium) Free Download. Free download the book Chemistry is for 9th class english medium students.
‘Six Sigma Technique’ A Journey Through its Implementationijtsrd
The manufacturing industries all over the world are facing tough challenges for growth, development and sustainability in today’s competitive environment. They have to achieve apex position by adapting with the global competitive environment by delivering goods and services at low cost, prime quality and better price to increase wealth and consumer satisfaction. Cost Management ensures profit, growth and sustainability of the business with implementation of Continuous Improvement Technique like Six Sigma. This leads to optimize Business performance. The method drives for customer satisfaction, low variation, reduction in waste and cycle time resulting into a competitive advantage over other industries which did not implement it. The main objective of this paper ‘Six Sigma Technique A Journey Through Its Implementation’ is to conceptualize the effectiveness of Six Sigma Technique through the journey of its implementation. Aditi Sunilkumar Ghosalkar "‘Six Sigma Technique’: A Journey Through its Implementation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64546.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64546/‘six-sigma-technique’-a-journey-through-its-implementation/aditi-sunilkumar-ghosalkar
Edge Computing in Space Enhancing Data Processing and Communication for Space...ijtsrd
Edge computing, a paradigm that involves processing data closer to its source, has gained significant attention for its potential to revolutionize data processing and communication in space missions. With the increasing complexity and data volume generated by modern space missions, traditional centralized computing approaches face challenges related to latency, bandwidth, and security. Edge computing in space, involving on board processing and analysis of data, offers promising solutions to these challenges. This paper explores the concept of edge computing in space, its benefits, applications, and future prospects in enhancing space missions. Manish Verma "Edge Computing in Space: Enhancing Data Processing and Communication for Space Missions" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64541.pdf Paper Url: https://www.ijtsrd.com/computer-science/artificial-intelligence/64541/edge-computing-in-space-enhancing-data-processing-and-communication-for-space-missions/manish-verma
Dynamics of Communal Politics in 21st Century India Challenges and Prospectsijtsrd
Communal politics in India has evolved through centuries, weaving a complex tapestry shaped by historical legacies, colonial influences, and contemporary socio political transformations. This research comprehensively examines the dynamics of communal politics in 21st century India, emphasizing its historical roots, socio political dynamics, economic implications, challenges, and prospects for mitigation. The historical perspective unravels the intricate interplay of religious identities and power dynamics from ancient civilizations to the impact of colonial rule, providing insights into the evolution of communalism. The socio political dynamics section delves into the contemporary manifestations, exploring the roles of identity politics, socio economic disparities, and globalization. The economic implications section highlights how communal politics intersects with economic issues, perpetuating disparities and influencing resource allocation. Challenges posed by communal politics are scrutinized, revealing multifaceted issues ranging from social fragmentation to threats against democratic values. The prospects for mitigation present a multifaceted approach, incorporating policy interventions, community engagement, and educational initiatives. The paper conducts a comparative analysis with international examples, identifying common patterns such as identity politics and economic disparities. It also examines unique challenges, emphasizing Indias diverse religious landscape, historical legacy, and secular framework. Lessons for effective strategies are drawn from international experiences, offering insights into inclusive policies, interfaith dialogue, media regulation, and global cooperation. By scrutinizing historical epochs, contemporary dynamics, economic implications, and international comparisons, this research provides a comprehensive understanding of communal politics in India. The proposed strategies for mitigation underscore the importance of a holistic approach to foster social harmony, inclusivity, and democratic values. Rose Hossain "Dynamics of Communal Politics in 21st Century India: Challenges and Prospects" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64528.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/history/64528/dynamics-of-communal-politics-in-21st-century-india-challenges-and-prospects/rose-hossain
Assess Perspective and Knowledge of Healthcare Providers Towards Elehealth in...ijtsrd
Background and Objective Telehealth has become a well known tool for the delivery of health care in Saudi Arabia, and the perspective and knowledge of healthcare providers are influential in the implementation, adoption and advancement of the method. This systematic review was conducted to examine the current literature base regarding telehealth and the related healthcare professional perspective and knowledge in the Kingdom of Saudi Arabia. Materials and Methods This systematic review was conducted by searching 7 databases including, MEDLINE, CINHAL, Web of Science, Scopus, PubMed, PsycINFO, and ProQuest Central. Studies on healthcare practitioners telehealth knowledge and perspectives published in English in Saudi Arabia from 2000 to 2023 were included. Boland directed this comprehensive review. The researchers examined each connected study using the AXIS tool, which evaluates cross sectional systematic reviews. Narrative synthesis was used to summarise and convey the data. Results Out of 1840 search results, 10 studies were included. Positive outlook and limited knowledge among providers were seen across trials. Healthcare professionals like telehealth for its ability to improve quality, access, and delivery, save time and money, and be successful. Age, gender, occupation, and work experience also affect health workers knowledge. In Saudi Arabia, healthcare professionals face inadequate expert assistance, patient privacy, internet connection concerns, lack of training courses, lack of telehealth understanding, and high costs while performing telemedicine. Conclusions Healthcare practitioners telehealth perceptions and knowledge were examined in this systematic study. Its collection of concerned experts different personal attitudes and expertise would help enhance telehealths implementation in Saudi Arabia, develop its healthcare delivery alternative, and eliminate frequent problems. Badriah Mousa I Mulayhi | Dr. Jomin George | Judy Jenkins "Assess Perspective and Knowledge of Healthcare Providers Towards Elehealth in Saudi Arabia: A Systematic Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64535.pdf Paper Url: https://www.ijtsrd.com/medicine/other/64535/assess-perspective-and-knowledge-of-healthcare-providers-towards-elehealth-in-saudi-arabia-a-systematic-review/badriah-mousa-i-mulayhi
The Impact of Digital Media on the Decentralization of Power and the Erosion ...ijtsrd
The impact of digital media on the distribution of power and the weakening of traditional gatekeepers has gained considerable attention in recent years. The adoption of digital technologies and the internet has resulted in declining influence and power for traditional gatekeepers such as publishing houses and news organizations. Simultaneously, digital media has facilitated the emergence of new voices and players in the media industry. Digital medias impact on power decentralization and gatekeeper erosion is visible in several ways. One significant aspect is the democratization of information, which enables anyone with an internet connection to publish and share content globally, leading to citizen journalism and bypassing traditional gatekeepers. Another aspect is the disruption of conventional media industry business models, as traditional organizations struggle to adjust to the decrease in advertising revenue and the rise of digital platforms. Alternative business models, such as subscription models and crowdfunding, have become more prevalent, leading to the emergence of new players. Overall, the impact of digital media on the distribution of power and the weakening of traditional gatekeepers has brought about significant changes in the media landscape and the way information is shared. Further research is required to fully comprehend the implications of these changes and their impact on society. Dr. Kusum Lata "The Impact of Digital Media on the Decentralization of Power and the Erosion of Traditional Gatekeepers" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64544.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/political-science/64544/the-impact-of-digital-media-on-the-decentralization-of-power-and-the-erosion-of-traditional-gatekeepers/dr-kusum-lata
Online Voices, Offline Impact Ambedkars Ideals and Socio Political Inclusion ...ijtsrd
This research investigates the nexus between online discussions on Dr. B.R. Ambedkars ideals and their impact on social inclusion among college students in Gurugram, Haryana. Surveying 240 students from 12 government colleges, findings indicate that 65 actively engage in online discussions, with 80 demonstrating moderate to high awareness of Ambedkars ideals. Statistically significant correlations reveal that higher online engagement correlates with increased awareness p 0.05 and perceived social inclusion. Variations across colleges and a notable effect of college type on perceived social inclusion highlight the influence of contextual factors. Furthermore, the intersectional analysis underscores nuanced differences based on gender, caste, and socio economic status. Dr. Kusum Lata "Online Voices, Offline Impact: Ambedkar's Ideals and Socio-Political Inclusion - A Study of Gurugram District" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64543.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/political-science/64543/online-voices-offline-impact-ambedkars-ideals-and-sociopolitical-inclusion--a-study-of-gurugram-district/dr-kusum-lata
Problems and Challenges of Agro Entreprenurship A Studyijtsrd
Noting calls for contextualizing Agro entrepreneurs problems and challenges of the agro entrepreneurs and for greater attention to the Role of entrepreneurs in agro entrepreneurship research, we conduct a systematic literature review of extent research in agriculture entrepreneurship to overcome the study objectives of complications of agro entrepreneurs through various factors, Development of agriculture products is a key factor for the overall economic growth of agro entrepreneurs Agro Entrepreneurs produces firsthand large scale employment, utilizes the labor and natural resources, This research outlines the problems of Weather and Soil Erosions, Market price fluctuation, stimulates labor cost problems, reduces concentration of Price volatility, Dependency on Intermediaries, induces Limited Bargaining Power, and Storage and Transportation Costs. This paper mainly devoted to highlight Problems and challenges faced for the sustainable of Agro Entrepreneurs in India. Vinay Prasad B "Problems and Challenges of Agro Entreprenurship - A Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64540.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64540/problems-and-challenges-of-agro-entreprenurship--a-study/vinay-prasad-b
Comparative Analysis of Total Corporate Disclosure of Selected IT Companies o...ijtsrd
Disclosure is a process through which a business enterprise communicates with external parties. A corporate disclosure is communication of financial and non financial information of the activities of a business enterprise to the interested entities. Corporate disclosure is done through publishing annual reports. So corporate disclosure through annual reports plays a vital role in the life of all the companies and provides valuable information to investors. The basic objectives of corporate disclosure is to give a true and fair view of companies to the parties related either directly or indirectly like owner, government, creditors, shareholders etc. in the companies act, provisions have been made about mandatory and voluntary disclosure. The IT sector in India is rapidly growing, the trend to invest in the IT sector is rising and employment opportunities in IT sectors are also increasing. Therefore the IT sector is expected to have fair, full and adequate disclosure of all information. Unfair and incomplete disclosure may adversely affect the entire economy. A research study on disclosure practices of IT companies could play an important role in this regard. Hence, the present research study has been done to study and review comparative analysis of total corporate disclosure of selected IT companies of India and to put forward overall findings and suggestions with a view to increase disclosure score of these companies. The researcher hopes that the present research study will be helpful to all selected Companies for improving level of corporate disclosure through annual reports as well as the government, creditors, investors, all business organizations and upcoming researcher for comparative analyses of level of corporate disclosure with special reference to selected IT companies. Dr. Vaibhavi D. Thaker "Comparative Analysis of Total Corporate Disclosure of Selected IT Companies of India" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64539.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64539/comparative-analysis-of-total-corporate-disclosure-of-selected-it-companies-of-india/dr-vaibhavi-d-thaker
The Impact of Educational Background and Professional Training on Human Right...ijtsrd
This study investigated the impact of educational background and professional training on human rights awareness among secondary school teachers in the Marathwada region of Maharashtra, India. The key findings reveal that higher levels of education, particularly a master’s degree, and fields of study related to education, humanities, or social sciences are associated with greater human rights awareness among teachers. Additionally, both pre service teacher training and in service professional development programs focused on human rights education significantly enhance teacher’s knowledge, skills, and competencies in promoting human rights principles in their classrooms. Baig Ameer Bee Mirza Abdul Aziz | Dr. Syed Azaz Ali Amjad Ali "The Impact of Educational Background and Professional Training on Human Rights Awareness among Secondary School Teachers" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64529.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/64529/the-impact-of-educational-background-and-professional-training-on-human-rights-awareness-among-secondary-school-teachers/baig-ameer-bee-mirza-abdul-aziz
A Study on the Effective Teaching Learning Process in English Curriculum at t...ijtsrd
“One Language sets you in a corridor for life. Two languages open every door along the way” Frank Smith English as a foreign language or as a second language has been ruling in India since the period of Lord Macaulay. But the question is how much we teach or learn English properly in our culture. Is there any scope to use English as a language rather than a subject How much we learn or teach English without any interference of mother language specially in the classroom teaching learning scenario in West Bengal By considering all these issues the researcher has attempted in this article to focus on the effective teaching learning process comparing to other traditional strategies in the field of English curriculum at the secondary level to investigate whether they fulfill the present teaching learning requirements or not by examining the validity of the present curriculum of English. The purpose of this study is to focus on the effectiveness of the systematic, scientific, sequential and logical transaction of the course between the teachers and the learners in the perspective of the 5Es programme that is engage, explore, explain, extend and evaluate. Sanchali Mondal | Santinath Sarkar "A Study on the Effective Teaching Learning Process in English Curriculum at the Secondary Level of West Bengal" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd62412.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/62412/a-study-on-the-effective-teaching-learning-process-in-english-curriculum-at-the-secondary-level-of-west-bengal/sanchali-mondal
The Role of Mentoring and Its Influence on the Effectiveness of the Teaching ...ijtsrd
This paper reports on a study which was conducted to investigate the role of mentoring and its influence on the effectiveness of the teaching of Physics in secondary schools in the South West Region of Cameroon. The study adopted the convergent parallel mixed methods design, focusing on respondents in secondary schools in the South West Region of Cameroon. Both quantitative and qualitative data were collected, analysed separately, and the results were compared to see if the findings confirm or disconfirm each other. The quantitative analysis found that majority of the respondents 72 of Physics teachers affirmed that they had more experienced colleagues as mentors to help build their confidence, improve their teaching, and help them improve their effectiveness and efficiency in guiding learners’ achievements. Only 28 of the respondents disagreed with these statements. With majority respondents 72 agreeing with the statements, it implies that in most secondary schools, experienced Physics teachers act as mentors to build teachers’ confidence in teaching and improving students’ learning. The interview qualitative data analysis summarized how secondary school Principals use meetings with mentors and mentees to promote mentorship in the school milieu. This has helped strengthen teachers’ classroom practices in secondary schools in the South West Region of Cameroon. With the results confirming each other, the study recommends that mentoring should focus on helping teachers employ social interactions and instructional practices feedback and clarity in teaching that have direct measurable impact on students’ learning achievements. Andrew Ngeim Sumba | Frederick Ebot Ashu | Peter Agborbechem Tambi "The Role of Mentoring and Its Influence on the Effectiveness of the Teaching of Physics in Secondary Schools in the South West Region of Cameroon" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64524.pdf Paper Url: https://www.ijtsrd.com/management/management-development/64524/the-role-of-mentoring-and-its-influence-on-the-effectiveness-of-the-teaching-of-physics-in-secondary-schools-in-the-south-west-region-of-cameroon/andrew-ngeim-sumba
Design Simulation and Hardware Construction of an Arduino Microcontroller Bas...ijtsrd
This study primarily focuses on the design of a high side buck converter using an Arduino microcontroller. The converter is specifically intended for use in DC DC applications, particularly in standalone solar PV systems where the PV output voltage exceeds the load or battery voltage. To evaluate the performance of the converter, simulation experiments are conducted using Proteus Software. These simulations provide insights into the input and output voltages, currents, powers, and efficiency under different state of charge SoC conditions of a 12V,70Ah rechargeable lead acid battery. Additionally, the hardware design of the converter is implemented, and practical data is collected through operation, monitoring, and recording. By comparing the simulation results with the practical results, the efficiency and performance of the designed converter are assessed. The findings indicate that while the buck converter is suitable for practical use in standalone PV systems, its efficiency is compromised due to a lower output current. Chan Myae Aung | Dr. Ei Mon "Design Simulation and Hardware Construction of an Arduino-Microcontroller Based DC-DC High-Side Buck Converter for Standalone PV System" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64518.pdf Paper Url: https://www.ijtsrd.com/engineering/mechanical-engineering/64518/design-simulation-and-hardware-construction-of-an-arduinomicrocontroller-based-dcdc-highside-buck-converter-for-standalone-pv-system/chan-myae-aung
Sustainable Energy by Paul A. Adekunte | Matthew N. O. Sadiku | Janet O. Sadikuijtsrd
Energy becomes sustainable if it meets the needs of the present without compromising the ability of future generations to meet their own needs. Some of the definitions of sustainable energy include the considerations of environmental aspects such as greenhouse gas emissions, social, and economic aspects such as energy poverty. Generally far more sustainable than fossil fuel are renewable energy sources such as wind, hydroelectric power, solar, and geothermal energy sources. Worthy of note is that some renewable energy projects, like the clearing of forests to produce biofuels, can cause severe environmental damage. The sustainability of nuclear power which is a low carbon source is highly debated because of concerns about radioactive waste, nuclear proliferation, and accidents. The switching from coal to natural gas has environmental benefits, including a lower climate impact, but could lead to delay in switching to more sustainable options. “Carbon capture and storage” can be built into power plants to remove the carbon dioxide CO2 emissions, but this technology is expensive and has rarely been implemented. Leading non renewable energy sources around the world is fossil fuels, coal, petroleum, and natural gas. Nuclear energy is usually considered another non renewable energy source, although nuclear energy itself is a renewable energy source, but the material used in nuclear power plants is not. The paper addresses the issue of sustainable energy, its attendant benefits to the future generation, and humanity in general. Paul A. Adekunte | Matthew N. O. Sadiku | Janet O. Sadiku "Sustainable Energy" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64534.pdf Paper Url: https://www.ijtsrd.com/engineering/electrical-engineering/64534/sustainable-energy/paul-a-adekunte
Concepts for Sudan Survey Act Implementations Executive Regulations and Stand...ijtsrd
This paper aims to outline the executive regulations, survey standards, and specifications required for the implementation of the Sudan Survey Act, and for regulating and organizing all surveying work activities in Sudan. The act has been discussed for more than 5 years. The Land Survey Act was initiated by the Sudan Survey Authority and all official legislations were headed by the Sudan Ministry of Justice till it was issued in 2022. The paper presents conceptual guidelines to be used for the Survey Act implementation and to regulate the survey work practice, standardizing the field surveys, processing, quality control, procedures, and the processes related to survey work carried out by the stakeholders and relevant authorities in Sudan. The conceptual guidelines are meant to improve the quality and harmonization of geospatial data and to aid decision making processes as well as geospatial information systems. The established comprehensive executive regulations will govern and regulate the implementation of the Sudan Survey Geomatics Act in all surveying and mapping practices undertaken by the Sudan Survey Authority SSA and state local survey departments for public or private sector organizations. The targeted standards and specifications include the reference frame, projection, coordinate systems, and the guidelines and specifications that must be followed in the field of survey work, processes, and mapping products. In the last few decades, there has been a growing awareness of the importance of geomatics activities and measurements on the Earths surface in space and time, together with observing and mapping the changes. In such cases, data must be captured promptly, standardized, and obtained with more accuracy and specified in much detail. The paper will also highlight the current situation in Sudan, the degree to which survey standards are used, the problems encountered, and the errors that arise from not using the standards and survey specifications. Kamal A. A. Sami "Concepts for Sudan Survey Act Implementations - Executive Regulations and Standards" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63484.pdf Paper Url: https://www.ijtsrd.com/engineering/civil-engineering/63484/concepts-for-sudan-survey-act-implementations--executive-regulations-and-standards/kamal-a-a-sami
Towards the Implementation of the Sudan Interpolated Geoid Model Khartoum Sta...ijtsrd
The discussions between ellipsoid and geoid have invoked many researchers during the recent decades, especially during the GNSS technology era, which had witnessed a great deal of development but still geoid undulation requires more investigations. To figure out a solution for Sudans local geoid, this research has tried to intake the possibility of determining the geoid model by following two approaches, gravimetric and geometrical geoid model determination, by making use of GNSS leveling benchmarks at Khartoum state. The Benchmarks are well distributed in the study area, in which, the horizontal coordinates and the height above the ellipsoid have been observed by GNSS while orthometric heights were carried out using precise leveling. The Global Geopotential Model GGM represented in EGM2008 has been exploited to figure out the geoid undulation at the benchmarks in the study area. This is followed by a fitting process, that has been done to suit the geoid undulation data which has been computed using GNSS leveling data and geoid undulation inspired by the EGM2008. Two geoid surfaces were created after the fitting process to ensure that they are identical and both of them could be counted for getting the same geoid undulation with an acceptable accuracy. In this respect, statistical operation played an important role in ensuring the consistency and integrity of the model by applying cross validation techniques splitting the data into training and testing datasets for building the geoid model and testing its eligibility. The geometrical solution for geoid undulation computation has been utilized by applying straightforward equations that facilitate the calculation of the geoid undulation directly through applying statistical techniques for the GNSS leveling data of the study area to get the common equation parameters values that could be utilized to calculate geoid undulation of any position in the study area within the claimed accuracy. Both systems were checked and proved eligible to be used within the study area with acceptable accuracy which may contribute to solving the geoid undulation problem in the Khartoum area, and be further generalized to determine the geoid model over the entire country, and this could be considered in the future, for regional and continental geoid model. Ahmed M. A. Mohammed. | Kamal A. A. Sami "Towards the Implementation of the Sudan Interpolated Geoid Model (Khartoum State Case Study)" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63483.pdf Paper Url: https://www.ijtsrd.com/engineering/civil-engineering/63483/towards-the-implementation-of-the-sudan-interpolated-geoid-model-khartoum-state-case-study/ahmed-m-a-mohammed
Activating Geospatial Information for Sudans Sustainable Investment Mapijtsrd
Sudan is witnessing an acceleration in the processes of development and transformation in the performance of government institutions to raise the productivity and investment efficiency of the government sector. The development plans and investment opportunities have focused on achieving national goals in various sectors. This paper aims to illuminate the path to the future and provide geospatial data and information to develop the investment climate and environment for all sized businesses, and to bridge the development gap between the Sudan states. The Sudan Survey Authority SSA is the main advisor to the Sudan Government in conducting surveying, mappings, designing, and developing systems related to geospatial data and information. In recent years, SSA made a strategic partnership with the Ministry of Investment to activate Geospatial Information for Sudans Sustainable Investment and in particular, for the preparation and implementation of the Sudan investment map, based on the directives and objectives of the Ministry of Investment MI in Sudan. This paper comes within the framework of activating the efforts of the Ministry of Investment to develop technical investment services by applying techniques adopted by the Ministry and its strategic partners for advancing investment processes in the country. Kamal A. A. Sami "Activating Geospatial Information for Sudan's Sustainable Investment Map" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63482.pdf Paper Url: https://www.ijtsrd.com/engineering/information-technology/63482/activating-geospatial-information-for-sudans-sustainable-investment-map/kamal-a-a-sami
Educational Unity Embracing Diversity for a Stronger Societyijtsrd
In a rapidly changing global landscape, the importance of education as a unifying force cannot be overstated. This paper explores the crucial role of educational unity in fostering a stronger and more inclusive society through the embrace of diversity. By examining the benefits of diverse learning environments, the paper aims to highlight the positive impact on societal strength. The discussion encompasses various dimensions, from curriculum design to classroom dynamics, and emphasizes the need for educational institutions to become catalysts for unity in diversity. It highlights the need for a paradigm shift in educational policies, curricula, and pedagogical approaches to ensure that they are reflective of the diverse fabric of society. This paper also addresses the challenges associated with implementing inclusive educational practices and offers practical strategies for overcoming barriers. It advocates for collaborative efforts between educational institutions, policymakers, and communities to create a supportive ecosystem that promotes diversity and unity. Mr. Amit Adhikari | Madhumita Teli | Gopal Adhikari "Educational Unity: Embracing Diversity for a Stronger Society" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64525.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/64525/educational-unity-embracing-diversity-for-a-stronger-society/mr-amit-adhikari
Integration of Indian Indigenous Knowledge System in Management Prospects and...ijtsrd
The diversity of indigenous knowledge systems in India is vast and can vary significantly between different communities and regions. Preserving and respecting these knowledge systems is crucial for maintaining cultural heritage, promoting sustainable practices, and fostering cross cultural understanding. In this paper, an overview of the prospects and challenges associated with incorporating Indian indigenous knowledge into management is explored. It is found that IIKS helps in management in many areas like sustainable development, tourism, food security, natural resource management, cultural preservation and innovation, etc. However, IIKS integration with management faces some challenges in the form of a lack of documentation, cultural sensitivity, language barriers legal framework, etc. Savita Lathwal "Integration of Indian Indigenous Knowledge System in Management: Prospects and Challenges" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63500.pdf Paper Url: https://www.ijtsrd.com/management/accounting-and-finance/63500/integration-of-indian-indigenous-knowledge-system-in-management-prospects-and-challenges/savita-lathwal
DeepMask Transforming Face Mask Identification for Better Pandemic Control in...ijtsrd
The COVID 19 pandemic has highlighted the crucial need of preventive measures, with widespread use of face masks being a key method for slowing the viruss spread. This research investigates face mask identification using deep learning as a technological solution to be reducing the risk of coronavirus transmission. The proposed method uses state of the art convolutional neural networks CNNs and transfer learning to automatically recognize persons who are not wearing masks in a variety of circumstances. We discuss how this strategy improves public health and safety by providing an efficient manner of enforcing mask wearing standards. The report also discusses the obstacles, ethical concerns, and prospective applications of face mask detection systems in the ongoing fight against the pandemic. Dilip Kumar Sharma | Aaditya Yadav "DeepMask: Transforming Face Mask Identification for Better Pandemic Control in the COVID-19 Era" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64522.pdf Paper Url: https://www.ijtsrd.com/engineering/electronics-and-communication-engineering/64522/deepmask-transforming-face-mask-identification-for-better-pandemic-control-in-the-covid19-era/dilip-kumar-sharma
Streamlining Data Collection eCRF Design and Machine Learningijtsrd
Efficient and accurate data collection is paramount in clinical trials, and the design of Electronic Case Report Forms eCRFs plays a pivotal role in streamlining this process. This paper explores the integration of machine learning techniques in the design and implementation of eCRFs to enhance data collection efficiency. We delve into the synergies between eCRF design principles and machine learning algorithms, aiming to optimize data quality, reduce errors, and expedite the overall data collection process. The application of machine learning in eCRF design brings forth innovative approaches to data validation, anomaly detection, and real time adaptability. This paper discusses the benefits, challenges, and future prospects of leveraging machine learning in eCRF design for streamlined and advanced data collection in clinical trials. Dhanalakshmi D | Vijaya Lakshmi Kannareddy "Streamlining Data Collection: eCRF Design and Machine Learning" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63515.pdf Paper Url: https://www.ijtsrd.com/biological-science/biotechnology/63515/streamlining-data-collection-ecrf-design-and-machine-learning/dhanalakshmi-d
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1. International Journal of Trend in
International Open Access Journal
ISSN No: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Brief Review o
V. Viswanatha1
, C.
1
Assistant Professor
1,3,4
Department of Pharmaceutics,
P. Rami Reddy Memorial
ABSTRACT
Liquid crystal (LC) is the substances that flow like
liquids but maintain some of the ordered structure
characteristics of liquid crystals. Examined and
summarized the types of liquid crystals. Analyzed the
structural characteristic of smectic, nematic and
cholesteric liquid crystals. It is noted that cholesteric
liquid crystals are helically twisted structure and the
pitch of the helix which is temperature dependent and
individual chemical properties of liquid
compounds of cholesterol. Results on the influence of
temperature on rheological properties of cholesteric
liquid crystal are presents. This chapter describes
briefly about classification of liquid crystals their
structure and properties. the main aim of this review
article is to scientifically highlight phar
liquid crystals, its importance in current development
of targeted drug delivery system. Objects of this
review is also to provide in depth information of
pharmaceutical liquid crystal technology which
include advanced technology development.
Keyword: Pharmaceutical liquid crystals, history,
Liquid crystal displays, pharma and non
applications, structures, Drug delivery utilizing LCs.
INTRODUCTION
Liquid crystals (LCs) are matter in a state which has
properties between those of conventional liquids and
those of solid crystals. For example, a liquid crystal
may flow like a liquid, but its molecules may be
oriented in a crystal-like way [1]. These are
International Journal of Trend in Scientific Research and Development (IJTSRD)
International Open Access Journal | www.ijtsrd.com
ISSN No: 2456 - 6470 | Volume - 2 | Issue – 6 | Sep
www.ijtsrd.com | Volume – 2 | Issue – 6 | Sep-Oct 2018
Review of Liquid Crystals
, C. Rajaramb2
, S. R. Fathimac3
, D. Bhanu priyad
Assistant Professor, 2,3,4
Associate Professor
Department of Pharmaceutics, 2
Department of Pharmacology
Rami Reddy Memorial Collage of Pharmacy, Kadapa, Andhra Pradesh
the substances that flow like
liquids but maintain some of the ordered structure
characteristics of liquid crystals. Examined and
summarized the types of liquid crystals. Analyzed the
structural characteristic of smectic, nematic and
ystals. It is noted that cholesteric
liquid crystals are helically twisted structure and the
pitch of the helix which is temperature dependent and
individual chemical properties of liquid -crystalline
compounds of cholesterol. Results on the influence of
emperature on rheological properties of cholesteric
liquid crystal are presents. This chapter describes
briefly about classification of liquid crystals their
structure and properties. the main aim of this review
article is to scientifically highlight pharmaceutical
liquid crystals, its importance in current development
of targeted drug delivery system. Objects of this
review is also to provide in depth information of
pharmaceutical liquid crystal technology which
include advanced technology development.
Pharmaceutical liquid crystals, history,
pharma and non-pharma
applications, structures, Drug delivery utilizing LCs.
Liquid crystals (LCs) are matter in a state which has
properties between those of conventional liquids and
those of solid crystals. For example, a liquid crystal
may flow like a liquid, but its molecules may be
1]. These are many
different types of liquid phases, which can be
distinguished by their different optical properties
(such as texture). The contrasting areas in texture to
domains where the liquid –
oriented in different directions. Within a
however the particles are well ordered. LC materials
may not generally be in a liquid
(similarly as water may turn into ice or steam).
Liquid crystals can be divided into thermo
lyotropic and met allotropic phases. Thermo
and lyotropic liquid crystals consist mostly of organic
molecules, although a few minerals are also known.
Thermo tropic LCs exhibit a phase transition into the
liquid crystal phase as temperature is change.
Lyotropic LCs exhibit phase transition as a function
of both temperature and concentration of the liquid
crystal molecule in solvent (typically water). Met
allotropic LCs are compounds of both organic and
inorganic; their liquid crystal transition depends not
only on the inorganic and organic
of liquid crystals can be found both in the natural
world and in technological applications. Most
contemporary electronic displays use liquid crystals.
Lyotropic liquid crystalline phases are abundant in
living systems but can also be found in the mineral
world. For example, many proteins and cell
membrane are liquid crystals. Other well
examples of LCs are solutions of soap and various
related detergents, as well as the tobacco mosaic
virus, and some clays [3].
Research and Development (IJTSRD)
www.ijtsrd.com
6 | Sep – Oct 2018
Oct 2018 Page: 956
, D. Bhanu priyad4
Department of Pharmacology
Collage of Pharmacy, Kadapa, Andhra Pradesh, India
different types of liquid phases, which can be
distinguished by their different optical properties
(such as texture). The contrasting areas in texture to
crystals molecules are
oriented in different directions. Within a space,
however the particles are well ordered. LC materials
may not generally be in a liquid -crystal phase
(similarly as water may turn into ice or steam).
Liquid crystals can be divided into thermo tropic,
allotropic phases. Thermo tropic
and lyotropic liquid crystals consist mostly of organic
molecules, although a few minerals are also known.
LCs exhibit a phase transition into the
liquid crystal phase as temperature is change.
Lyotropic LCs exhibit phase transition as a function
of both temperature and concentration of the liquid
crystal molecule in solvent (typically water). Met
Cs are compounds of both organic and
inorganic; their liquid crystal transition depends not
only on the inorganic and organic ratio [2]. Example
of liquid crystals can be found both in the natural
world and in technological applications. Most
electronic displays use liquid crystals.
Lyotropic liquid crystalline phases are abundant in
living systems but can also be found in the mineral
world. For example, many proteins and cell
membrane are liquid crystals. Other well known
solutions of soap and various
related detergents, as well as the tobacco mosaic
2. International Journal of Trend in Scientific
@ IJTSRD | Available Online @ www.ijtsrd.com
Historical background:
1849: W. Heintz found that upon heating (t (at
52c), stearin, softened and become cloudy, and at
62.5 it becomes clear. Duffy partrayed this
phenomenon as the presents of two melting points
1950: Mettenheimier found myelin to be
birefringent, a property previously known to be
possessed by crystals only
1888: Reinitzer observed the two -
phenomenon, birefringence and the occurrence of
iridescent colors between the two melting points
in a material that we now was cholesteryl benzole
1889: Lehmann carried out detail tail investigation
and reasoned that the birefringent portions of the
liquid must be crystals. He previously referred to
this material as liquid crystals
Classification:
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 2 | Issue – 6 | Sep-Oct 2018
1849: W. Heintz found that upon heating (t (at
52c), stearin, softened and become cloudy, and at
ear. Duffy partrayed this
phenomenon as the presents of two melting points
1950: Mettenheimier found myelin to be
birefringent, a property previously known to be
-melting-points
birefringence and the occurrence of
iridescent colors between the two melting points
in a material that we now was cholesteryl benzole
carried out detail tail investigation
and reasoned that the birefringent portions of the
liquid must be crystals. He previously referred to
1890: Gattermann blended the principalfluid
precious crystals of azoxybenzene, with fully
known structures
1908: D. Vorlaender, the first to integrate a
thermotropic smectic compound, related liquid
crystallinity to chemical structures, detected
polymorphism of liquid crystal state
1922: Freidel identified and named thedifferent
microscopic textures (nematic, smectic, and
cholesteric), observed the impacts of electric and
magnetic fields
1930: Freedericksz studied the transition from a
homogeneoustructure at some critical valuer of
applied field strength
1965: the global liquid crystal society by late
Glenn Brown at kent state university. Lehmann
and Reinitzer are known as the grandfathers of
LCs science [4-5]
Research and Development (IJTSRD) ISSN: 2456-6470
Oct 2018 Page: 957
1890: Gattermann blended the principalfluid
precious crystals of azoxybenzene, with fully
1908: D. Vorlaender, the first to integrate a
thermotropic smectic compound, related liquid
crystallinity to chemical structures, detected
phism of liquid crystal state
1922: Freidel identified and named thedifferent
microscopic textures (nematic, smectic, and
cholesteric), observed the impacts of electric and
1930: Freedericksz studied the transition from a
re at some critical valuer of
1965: the global liquid crystal society by late
Glenn Brown at kent state university. Lehmann
and Reinitzer are known as the grandfathers of
3. International Journal of Trend in Scientific
@ IJTSRD | Available Online @ www.ijtsrd.com
Chemical structure: All the known molecules that
form liquid crystalline phases are asymmetric in
their shape.
Monomers can be attached: to in polymer back
bone forming side chain polymer
Characteristic features and properties:
point along a common axis, the director
Orientational arrange is between the
strong and fluid stages
Mesogens Anisotropic i.e. the properties very
contingent upon what course they are estimated
with respect to the chief
Birefriengent, resulting in the two components of
electric or magnetic field travelling through it at
different speed hence out of phase when they exit
Stiffness necessary for liquid crystallinity results
from restrictions on rotation caused by steric
hindrance and
Axial proportion (x=l/d) must be something like
three to display the attributes of liquid crystals
Properties:
Liquid crystal can flow like a liquid, due to loss of
positional order
Liquid crystal is optically birefringent, due to its
orientational order
Transition crystalline solid to liquid crystals
caused by a change of temperature –
THRMOTROPIC liquid crystals
Substances that are most likely to form a liquid
crystals phase at a certain temperature are
molecules that are ELONGATED
degree of rigidity [7].
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 2 | Issue – 6 | Sep-Oct 2018
All the known molecules that
form liquid crystalline phases are asymmetric in
to in polymer back
Monomers commonly used:
Cholesterol ester
Phenyl benzene
Surfactant
a long single chain forming main chain polymer
Paraffines
Glycolipids
Cellulose derivatives[6]
properties:
point along a common axis, the director
Orientational arrange is between the customary
Mesogens Anisotropic i.e. the properties very
contingent upon what course they are estimated
Birefriengent, resulting in the two components of
electric or magnetic field travelling through it at
when they exit
Stiffness necessary for liquid crystallinity results
from restrictions on rotation caused by steric
Axial proportion (x=l/d) must be something like
three to display the attributes of liquid crystals
ystal can flow like a liquid, due to loss of
Liquid crystal is optically birefringent, due to its
Transition crystalline solid to liquid crystals
– given rice to
Substances that are most likely to form a liquid
crystals phase at a certain temperature are
& have some
Temperature range problems
Methods of lowering the polymer melting
temperature:
Minimized interactions with reduced symmetry
Introduction of defects to disrupt the ability for
neigh boring polymers to line up
Molecules are assembled in
(head to tail, head to head)
Random copolymerization result in irregularity of
polymer substituents
LCs Display:
A liquid crystal display (LCD) is a flat
or other electronically regulated optical device that
uses the light -tweaking properties of liquid crystals.
Liquid crystals do not emit light display, instead usi
a backlight or reflector to produce image in color or
monochrome [8-9].
LCs consists of an array of tiny segments (called
pixels) that can be manipulated to present
information
LCD consist primary of two glass plates with
some liquid crystals material
Research and Development (IJTSRD) ISSN: 2456-6470
Oct 2018 Page: 958
Monomers commonly used:
a long single chain forming main chain polymer
Temperature range problems:
Methods of lowering the polymer melting
Minimized interactions with reduced symmetry
Introduction of defects to disrupt the ability for
polymers to line up
Molecules are assembled in arbitrary orientation
(head to tail, head to head)
Random copolymerization result in irregularity of
A liquid crystal display (LCD) is a flat -panel display
or other electronically regulated optical device that
tweaking properties of liquid crystals.
Liquid crystals do not emit light display, instead using
a backlight or reflector to produce image in color or
LCs consists of an array of tiny segments (called
pixels) that can be manipulated to present
LCD consist primary of two glass plates with
some liquid crystals material between them[10]
4. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Plates are usually manufactured with transparent
electrodes (ITO), that make it possible to apply an
electric field across small areas of the film of
liquid crystal
LCDs consume much less power
cathodes -ray tube (CRT) counterparts
Most usually utilised are the twisted nematic (TN)
Displays[11]
Advantages:
The liquid crystal display (LCDs)
Liquid crystals thermometers. Cholesteric liquid
crystals reflect light with a wavelength equal
the pitch which is dependent upon temperature
High strength fibers. Polymer liquid crystals are
used in applications calling for strong, lightweight
materials e.g. Kevlar
Optical imaging. Generation of electric field as
light falls on photoconductor plates
Drug delivery. Lyotropic liquid crystals can coat a
drug to keep it from being destroyed in the
digestive tract
Biological membrane. Lyotropic liquid crystals
act as biological membranes due to their
amphiphilic nature [12].
Latest Development in Pharmaceutical Liquid
Crystal Technology:
Kent state university, Summa health system and IC
MedTech have developed a new paradigm in drug
discovery based on the pharmacologic properties of
liquid crystal pharmaceuticals (LCs). LCPS are a
unique class of lyotropic liquid crystals that represent
novel drug candidates for a treatment of a wide range
of diseases. Representatives of this research project
recently filed applications for two new patients: one
for a new LCP-based anti -tumor drug called
TOLECINE and another for a formulation that
combines TOLECINE and another LCP, APATONE.
Olecine is a new pre-clinical anti-tumor LCP that also
has antiviral and antibacterial applications. It is
tumor- cell selective and exhibits a strong anti
neoplastic activity (it counteracts abnormal
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 2 | Issue – 6 | Sep-Oct 2018
Plates are usually manufactured with transparent
electrodes (ITO), that make it possible to apply an
electric field across small areas of the film of
LCDs consume much less power than their
ray tube (CRT) counterparts
are the twisted nematic (TN)
. Cholesteric liquid
crystals reflect light with a wavelength equal to
the pitch which is dependent upon temperature
. Polymer liquid crystals are
used in applications calling for strong, lightweight
. Generation of electric field as
Lyotropic liquid crystals can coat a
drug to keep it from being destroyed in the
. Lyotropic liquid crystals
act as biological membranes due to their
rmaceutical Liquid
Kent state university, Summa health system and IC -
MedTech have developed a new paradigm in drug
discovery based on the pharmacologic properties of
LCs). LCPS are a
ropic liquid crystals that represent
novel drug candidates for a treatment of a wide range
of diseases. Representatives of this research project
recently filed applications for two new patients: one
tumor drug called
another for a formulation that
combines TOLECINE and another LCP, APATONE.
tumor LCP that also
has antiviral and antibacterial applications. It is
cell selective and exhibits a strong anti-
neoplastic activity (it counteracts abnormal
proliferation of cells in a tissue or organ). Likewise,
has been appeared to be more visable than the present
standard of condition for herpes.
Apatone is a clinical phase investigational new drug
for late- stage prostate cancer. It is currently under
consideration for clinical study for potential
applications such as augmentation of chemotherapy to
allow lower, less toxic doses of common
chemotherapy agents. Apatone is made from two non
-toxic compounds, a liquid crystal compound and a
sugar, that selectively bio-concentrate with in a cancer
cell and produce a free radical. Formation of strong,
short lived free radical is a concentration driven
intracellular reaction and therefore only takes place in
cells with sufficient sugar concentrations (such as
cancer cells). The reaction results in oxidative stress
that weakens the targeted cells from within. It is
carried out quickly only within
no toxic reaction by products that might harm
adjacent healthy cells [13].
Pharma drugs as LCS:
Many little atomic pharmaceutical
compounds have been shown to frame LC meso
phases. Nafoxidine hydrochloride is one such
example; this cationic drug has amphiphilic properties
and gives rice thermo tropic (smectic type) and
lyotropic liquid crystalline structures. Palmitolyl
propranolol hydrochloride is an amphiphilic
derivative of beta-blocker propranolol hydrochloride
which forms smectic type liquid crystalline phase. It
has been administered as liquid crystalline dispersion
for cardiac problems. Itraconazole hydrochloride is an
antifungal medication which frames chiral nematic
stages. Some of the other examples of small
molecular pharmaceuticals which can from LCs are
arsphenamine, fenoprofen sodium, fenoprofen
calcium, penbutolol sulphate, nafci
folic acid and to bramycin. Large molecular
pharmaceutical active compounds are also known to
form LCs; some common
cyclosporin, calcitonin, amylin, nafarelin, detirelix,
and leuprolide. The recent research has yiel
investigational LC based anti
tolecine, a compound which also has antiviral and
antibacterial applications. Some of the pharmaceutical
excipients such as hydroxy propyl cellulose, ethyl
cellulose and cellulose acetate have also
phases. Besides this, examples of naturally occurring
LCs are DNA, cholesterol and the biological
membranes [14].
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Oct 2018 Page: 959
proliferation of cells in a tissue or organ). Likewise, it
has been appeared to be more visable than the present
standard of condition for herpes.
Apatone is a clinical phase investigational new drug
stage prostate cancer. It is currently under
consideration for clinical study for potential
ions such as augmentation of chemotherapy to
allow lower, less toxic doses of common
chemotherapy agents. Apatone is made from two non
toxic compounds, a liquid crystal compound and a
concentrate with in a cancer
ce a free radical. Formation of strong,
short lived free radical is a concentration driven
intracellular reaction and therefore only takes place in
cells with sufficient sugar concentrations (such as
cancer cells). The reaction results in oxidative stress
that weakens the targeted cells from within. It is
within the cancer cells, with
no toxic reaction by products that might harm
Pharma drugs as LCS:
Many little atomic pharmaceutical dynamic
have been shown to frame LC meso
phases. Nafoxidine hydrochloride is one such
this cationic drug has amphiphilic properties
tropic (smectic type) and
lline structures. Palmitolyl
propranolol hydrochloride is an amphiphilic
blocker propranolol hydrochloride
liquid crystalline phase. It
has been administered as liquid crystalline dispersion
Itraconazole hydrochloride is an
antifungal medication which frames chiral nematic
stages. Some of the other examples of small
molecular pharmaceuticals which can from LCs are
arsphenamine, fenoprofen sodium, fenoprofen
calcium, penbutolol sulphate, nafcillin, methotrexate,
bramycin. Large molecular
pharmaceutical active compounds are also known to
form LCs; some common examples of them are
cyclosporin, calcitonin, amylin, nafarelin, detirelix,
and leuprolide. The recent research has yielded a new
investigational LC based anti-tumor drug called
tolecine, a compound which also has antiviral and
antibacterial applications. Some of the pharmaceutical
excipients such as hydroxy propyl cellulose, ethyl
cellulose and cellulose acetate have also displayed LC
phases. Besides this, examples of naturally occurring
LCs are DNA, cholesterol and the biological
5. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Drug delivery utilizing liquid crystal structure
Vitamin E TPGS/drug compositions and methods are
provided which abviate the need for surfactants or
non-evaporated co solvents because the active drug
component is dissolved directly onto vitamin E TPGs
to form a true molecular solution -not an emulsion or
a micro emulsion. The innovation gives a gradually
dissolving TPGS/sedate framework that ingests
gastrointestinal liquid into the grid at the
measurement shape/liquid interface, where a gel like
liquid crystal is formed [15]. This gel front structures
a liquid crystal limit where tranquilize disintegration
is most. At this liquid crystal/GI fluid boundary,
synchronization takes place in which the rare of
formation of liquid crystal equal the dissolution rate
of liquid crystals at the water interface, thereby giving
controlled order release of the drug into the GI
tract[16]. The rate of disintegration is additionally
controlled by the geometry of the measurement shape.
The solid vitamin E TPGS/drug matrices of the
invention can be solidified and compressed into tablet
or filled into capsules, with other excipients, binders
and / or fillers [17]. The solid TPGS/drug solution of
the invention also can be made into an immediate
release liquid formation upon addition of water, or
into a controlled release system liquid formation up
on addition of water, or into a controlled release
system solid tablet by the use of impermeable or
permeable barrier or coatings surrounding portions of
the tablet [18].
Applications in pharma:
It has been estimated that approximately 5 percent of
all organic molecules are able to exist as temperature
LCs. Pharmaceutical compounds have been
increasingly characterized by their lyotropic liquid
crystalline states with relatively fewer examples of
thermo tropic LC states. LLCs based delivery system
such as creams, ointments, gels, liposomes, colloidal
dispersions and transdermal patches have been used in
pharmaceuticals and cosmetics.
Non-Pharma applications of liquid crystals:
Liquid crystal displays
Liquid crystal thermometers
Optical imaging
Liquid crystal technology has had a major effect many
areas of science and engineering, as well as device
technology. Applications for this special kind of
material are still being discovered and continue to
provide effective solution to different problems
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 2 | Issue – 6 | Sep-Oct 2018
Drug delivery utilizing liquid crystal structure:
Vitamin E TPGS/drug compositions and methods are
d for surfactants or
solvents because the active drug
component is dissolved directly onto vitamin E TPGs
not an emulsion or
a micro emulsion. The innovation gives a gradually
ework that ingests
gastrointestinal liquid into the grid at the
measurement shape/liquid interface, where a gel like
15]. This gel front structures
a liquid crystal limit where tranquilize disintegration
ystal/GI fluid boundary,
synchronization takes place in which the rare of
formation of liquid crystal equal the dissolution rate
of liquid crystals at the water interface, thereby giving
controlled order release of the drug into the GI
of disintegration is additionally
controlled by the geometry of the measurement shape.
The solid vitamin E TPGS/drug matrices of the
invention can be solidified and compressed into tablet
or filled into capsules, with other excipients, binders
17]. The solid TPGS/drug solution of
the invention also can be made into an immediate
release liquid formation upon addition of water, or
into a controlled release system liquid formation up
on addition of water, or into a controlled release
olid tablet by the use of impermeable or semi
barrier or coatings surrounding portions of
It has been estimated that approximately 5 percent of
all organic molecules are able to exist as temperature
Pharmaceutical compounds have been
increasingly characterized by their lyotropic liquid
crystalline states with relatively fewer examples of
tropic LC states. LLCs based delivery system
such as creams, ointments, gels, liposomes, colloidal
ns and transdermal patches have been used in
Pharma applications of liquid crystals:
Liquid crystal technology has had a major effect many
areas of science and engineering, as well as device
technology. Applications for this special kind of
material are still being discovered and continue to
provide effective solution to different problems.
Liquid crystals have a multitude of other uses. They
are used for non-destructive
materials under stress. This strategy is likewise for the
perception of RF (radio recurrence) waves in
waveguides. They are used in medical applicatio
where, for example, transient pressure transmitted by
a walking foot on the ground is measured. Low molar
mass (LMM) liquid crystal have applications
including erasable optical disks, full color “electronic
slides” for computer- aided drawing (CAD), and
modulators for color electronic imaging.
As a new properties and types of liquid crystals are
investigated and researched, these materials are sure
to gain increasing importance in industrial and
scientific application [19].
Conclusion:
There are three states of matter
A fourth condition of issue is the fluidcrystalline state.
The term liquid crystal is an apparent contradiction,
but it is useful in a descriptive sense because material
in this state are in many ways interm
the liquid and solid states. The liquid crystalline state
may result either from the heating of solids or from
the action of certain solvents or solids (lyotropic
liquid crystals). LLCs based delivery systems such as
creams, ointments, gels, liposomes, colloidal
dispersions and transdermal patches have been used in
pharmaceuticals and cosmetics. Liquid crystals
method for sedate conveyance
helpful for conveying the medication with wanted
target. This technique can be utilized largely in topical
delivery of the drug as it passes the advantages of
smooth feel and drug loading of incompatible
molecule. Day by day various pa
this liquid- crystals technique. This technique of drug
loading is a new and immerging techniques requires
attention further for its practice in real scientific
industries to deliver a quality outcome for a society.
Non -pharma applications LCs are LCS displays, LCS
thermometers and optical imaging. As research into
this field continues and as new applications are
developed, liquid crystals will play a vital role in
modern technology.
References:
1. Collings, P. J. & Hird, M. (1997). Introduction to
Liquid Crystals. Bristol, PA: Taylor & Francis.
ISBN 0-7484-0643-3.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Oct 2018 Page: 960
Liquid crystals have a multitude of other uses. They
destructive mechanical testing of
materials under stress. This strategy is likewise for the
radio recurrence) waves in
waveguides. They are used in medical applications
where, for example, transient pressure transmitted by
a walking foot on the ground is measured. Low molar
mass (LMM) liquid crystal have applications
including erasable optical disks, full color “electronic
aided drawing (CAD), and light
modulators for color electronic imaging.
As a new properties and types of liquid crystals are
investigated and researched, these materials are sure
to gain increasing importance in industrial and
re three states of matter -gas liquid and solid.
A fourth condition of issue is the fluidcrystalline state.
The term liquid crystal is an apparent contradiction,
but it is useful in a descriptive sense because material
in this state are in many ways intermediate between
the liquid and solid states. The liquid crystalline state
may result either from the heating of solids or from
the action of certain solvents or solids (lyotropic
liquid crystals). LLCs based delivery systems such as
s, liposomes, colloidal
dispersions and transdermal patches have been used in
pharmaceuticals and cosmetics. Liquid crystals
sedate conveyance can be a viable and
helpful for conveying the medication with wanted
target. This technique can be utilized largely in topical
delivery of the drug as it passes the advantages of
smooth feel and drug loading of incompatible
molecule. Day by day various patients are coming in
crystals technique. This technique of drug
loading is a new and immerging techniques requires
attention further for its practice in real scientific
industries to deliver a quality outcome for a society.
ications LCs are LCS displays, LCS
thermometers and optical imaging. As research into
this field continues and as new applications are
developed, liquid crystals will play a vital role in
Hird, M. (1997). Introduction to
Liquid Crystals. Bristol, PA: Taylor & Francis.
6. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
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(1974). Introduction to Liquid Crystals. Plenum
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“International Max Planck Research School
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Bad Marienberg, September 14, 2006:27
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(2004). Crystals That Flow – classic papers from
the history of liquid crystals. London: Taylor &
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(1962) Molecular Structure and the Properties of
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Węgłowska, D. (2017). "Mesomorphic and
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anck Research School
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of an Industry. World Scientific Publishing.
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system utilizing liquid crystal structure” US
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Liquid Crystals in” Encyclopedia of
Pharmaceutical Technology, Chapter 75, Third
Edition Informa Healthcare
Imran K. Tadwee, Sourabh Gore, Prashant
Giradkar “Advances in Topical Drug Delivery
System: A Review” Int. J. of Pharm. Res. & All.
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