The document discusses several topics related to genetics and biology:
1) Mutations can affect gene expression and the amino acid sequence of proteins. Specialization of cells is usually due to differences in gene expression, not the genes themselves.
2) Genetic engineering is used to produce novel products by inserting exogenous DNA into bacterial cells to alter their genetics and express new proteins.
3) The immune system relies on phagocytes, B-lymphocytes, T-lymphocytes to protect against infection, as well as antibodies and vaccination.
4) Breast cancer is discussed in relation to mutation, heredity, and the immune response working to protect against disease. Mutation and hered
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
contains descriptive and other studies on genetics and epigenetics and whole gene concepts from central dogma to future concepts . Dr Harshavardhan Patwal
Introducing AGiR: Action for Genomic integrity through Research Rachel Aronoff
Action for genomic integrity
cigarettes, hair dye ingredients, UV light, all affect health in part due to effects on genomic integrity, our molecular heritage, so to speak. Our cells need saving and future generations need protection too. see more in the site!
How Plants Avoid Sunburn: Findings Could Lead to Crops With Increased Protection from Bright Light and Enhanced Photosynthesis and- Cell MemoryMechanism Discovered
This paper highlights mainly on gene therapy for oral cancer
Oral cancer is one of the deadly disease which need a different vision of treatment because of its pooor prognosis rate.
This paper highlights the basic idea of gene therapy , techniques , steps , its merits & limitations.
Gene Therapy: Central concept of gene therapy, basic molecular mechanism of gene transfer, prerequisite of human gene therapy, biological basis of gene therapy strategies, vehicles for gene transfer, Antisence oligonucleotides and RNAi, clinical gene therapy studies, gene therapy for hereditary disease, gene therapy for cancer, gene therapy for HIV.
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
contains descriptive and other studies on genetics and epigenetics and whole gene concepts from central dogma to future concepts . Dr Harshavardhan Patwal
Introducing AGiR: Action for Genomic integrity through Research Rachel Aronoff
Action for genomic integrity
cigarettes, hair dye ingredients, UV light, all affect health in part due to effects on genomic integrity, our molecular heritage, so to speak. Our cells need saving and future generations need protection too. see more in the site!
How Plants Avoid Sunburn: Findings Could Lead to Crops With Increased Protection from Bright Light and Enhanced Photosynthesis and- Cell MemoryMechanism Discovered
This paper highlights mainly on gene therapy for oral cancer
Oral cancer is one of the deadly disease which need a different vision of treatment because of its pooor prognosis rate.
This paper highlights the basic idea of gene therapy , techniques , steps , its merits & limitations.
Gene Therapy: Central concept of gene therapy, basic molecular mechanism of gene transfer, prerequisite of human gene therapy, biological basis of gene therapy strategies, vehicles for gene transfer, Antisence oligonucleotides and RNAi, clinical gene therapy studies, gene therapy for hereditary disease, gene therapy for cancer, gene therapy for HIV.
Gene therapy is the process of inserting therapeutic genes into cells to prevent or cure wide range of diseases. The newly introduced genes will encode proteins and correct the deficiencies that occur in genetic diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease, and keep organism in good health. It is a technique for correcting defective genes responsible for disease and development.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. 4c Students know how mutations in the DNA sequence of a
gene may or may not affect the expression of the gene, or
the sequence of amino acids in an encoded protein.
4d Students know how specialization of cells in multicellular
organisms is usually due to different patterns of gene
expression rather than to differences in the genes themselves.
5c Students know how genetic engineering (biotechnology)
is used to produce novel biomedical and agricultural
products.
5e Students know how exogenous DNA can be inserted into
bacterial cells to alter their genetic makeup and support
expression of new protein products.
3. 10f Students know the roles of phagocytes, B-lymphocytes, and
T-lympho10a Students know the role of the skin in providing
nonspecific diseases against infection.
10b Students know the role of antibodies in the body’s response
to infection.
10c Students know how vaccination protects an individual from
infectious diseases.
10d Students know there are important differences between
bacteria and viruses with respect to their requirements for growth
and replication, the body’s primary defenses against bacterial
and viral infections, and effective treatments of those infections.
10e Students know why an individual with a compromised
immune system (for example, a person with AIDS), may be
unable to fight off and survive infections by microorganisms that
are usually benign.cytes in the immune system.
4. I chose these standards because it unites
how breast cancer works like the immune
response works with mutation
It works like your body works when you
need it to work
You lease expect a new disease in your
body like beast cancer you wont notice
it until you get a physical check up
5. Cancer is a term
used for diseases in
which abnormal cells
divide without
control and are able
to invade other
tissues.
6. Breast cancer is combined with
mutation.
Its combined with it because cancer is a
type of mutation and mutation is
something that has something to do with
your DNA.
Mutation changes part of your DNA.
Breast cancer is a type of mutation
because it changes you DNA and parts
of your body
7.
8.
9. Mutation are
changes in a
genomic
sequence.
Mutation are
caused by
radiation, virus
es, and
transposons
10. They can also be induce by
the organism itself
A mutation is passed to the
offspring stably, unless it is a
“dynamic mutation”
11. Mutation can result in several different
type of change in sequence (RNA) these
can either have no effect, or prevent the
gene from functioning properly or
completely
Mutation changes a protein produced
by a gene.
12. Breast cancer is combined with heredity
because its in your DNA.
Like in a heredity is with DOMINAD and
RESSEVES it all depends on your family
records
13. Heredity is the
passing to
offspring from its
parent or ancestors
Through
heredity, variation
exhibited by
individuals can
accumulate and
cause some
species to evolve.
14. In humans eye color is an inherited
characteristic and an individual might
inherit the brown eye trait from one of
the parents
Heritable traits are known to be passed
from one generation to the next via
DNA, a molecule that encodes genetic
information
15. Before a cell divides, the DNA
is copied , so that each of the
resulting two cells will inherit
the DNA sequence
The specific location of the
DNA sequence within a
chromosome is known as a
locus
16. Immune response is combined with
breast cancer because it tries to protect
people from disease
This all response with the standards
because mutation has to do with the
DNA also like the heredity and the
immune response with fighting with the
diseases
17. A immune response is a system
biological structures and processes
with in a organism that project against
disease .
Immune response consists of many
type of proteins, cells, organs, and
tissues that interact in an elaborate
and dynamic network
18. This process of
acquired immunity
is the basis of
vaccination.
A immune response
protects organisms
from infection with
layered defenses of
increasing
specificity
19. Immunity depends on the
ability of the immune response
to distinguish between self and
non-self molecules
“the earliest known mention of
immunity was during the
plague of Athens in 430 BC.”
20. Breast cancer is a cancer
originating from breast
tissue
Treatment may include
surgery, drugs, radiation
21. „in 2008 , breast cancer caused
458,503 deaths worldwide (13.7%
of cancer deaths in women).
“a genetic mutation implicated in
breast and ovarian cancer could
also have a role in causing heart
failure.
22. Unknown Author. (15 Oct 2009 - 3:00 PST). Common Genetic Mutation In Breast Cancer May
Point To New Treatments For Heart Disease. Medical News Today. 6 Feb 2012, from
http://www.medicalnewstoday.com/releases/167422.php
Unknown author. (May 25th, 2011). BIRTH DEFECTS AND HEREDITY: HEREDITY. Preparing to be
best parents & relating to children. 8 February 2012, from
http://www.parentchildcare.co.uk/birth-defects-and-heredity-heredity
Unknown author. (No date) Breast cancer tumor. Natural health is our DNA. 8 February
2012, from http://www.encognitive.com/node/10399
Unknown author. (Updated: 6 February, 2012). What is cancer? Nation cancer institute. 8
February 2012, from
http://www.cancer.gov/cancertopics/cancerlibrary/what-is-cancer
Unknown author. (To many dates). Meditation helps women affected by breast cancer.
Health spa blog. 8 February 2012, from http://www.healthspablog.org/?s=breast+cancer
Jimmy Donal. (Last modified 9 February 2012). Mutation. Wikipedia the free encyclopedia. 8
February 2012, from http://www.medicalnewstoday.com/releases/167422.php