The document summarizes research on the potential link between exposure to bisphenol A (BPA) and increased risk of prostate cancer. BPA is used to make plastics and resins and can leach from food containers into food. A study found that low BPA doses promoted abnormal cell growth and centromere amplification in vitro. The study also found higher BPA levels in younger prostate cancer patients. However, the American Chemistry Council criticized the study, noting human exposure data is limited. More research is still needed to fully understand any health risks from BPA exposure.
Bisphenol A (BPA) is a chemical used to make plastics and resins. This document summarizes studies linking BPA exposure to prostate cancer risk. Animal and cell studies show BPA can disrupt cell division and centromeres, increasing abnormal cell growth. Urinary BPA levels correlate with earlier prostate cancer onset. However, human studies are needed to confirm effects, as animal results aren't always reproducible. While more research is warranted, current evidence raises concerns about BPA exposure and prostate cancer risk.
Bisphenol A (BPA) is a synthetic compound used primarily to make plastics and epoxy resins. It is found in many consumer products. There is ongoing controversy around the health effects of BPA. Some studies link BPA exposure to neurological effects, heart and kidney disease in children, breast cancer, and disrupted hormone function. However, others argue that levels of active BPA in humans are very low. While some regulatory bodies have taken action to restrict BPA, the health risks from exposure to BPA remain an area of ongoing research and debate.
Testing of neutraceuticals and food productsAbhishek Rana
Testing of neutraceuticals and food products includes Testing of microbial load, nutritional value, heavy
metals, calorific value and neutraceutical label claim test.
Brief introduction to Agmark, Bureau of Indian Standards (BIS) and Food Safety and Standards
Authority of India (FSSAI).
This document discusses lycopene, a carotenoid pigment found in tomatoes and other red fruits and vegetables. It provides lycopene's sources, history of research on it, levels of intake in different populations, content in various foods, biological activities including antioxidant effects, and potential health benefits related to reducing risks of certain cancers and cardiovascular disease. The Pennington Nutrition Series publishes research from the Pennington Biomedical Research Center on nutrition, chronic disease prevention, and healthy aging.
Bio-plastics are plastics that are either derived from renewable biomass sources like vegetable oils or are biodegradable. There are several types of bio-plastics including starch-based, cellulose-based, and aliphatic polyesters like PLA and PHA which are produced by bacteria. Compared to conventional plastics, bio-plastics have benefits like lower carbon emissions, lower toxicity, and some can biodegrade, but they also have drawbacks like higher costs and potential issues with GMOs. Bio-plastics production is growing due to advantages for certain applications and their more environmentally friendly nature.
In this slide contains need of food regulations, system and Legislation Regulation of Food Products as per BSI and Agmark.
Presented by: G. Chiranjeevi (Department of pharmaceutical analysis),
RIPER, anantapur.
Formation of polycyclic aromatic hydrocarbons in traditionally smoked fish re...ILRI
Presentation by Yolande Aké Assi, Axel Sess, Henri Godi Biégo, Mathias Koffi, Patrice Kouamé and Bassirou Bonfoh at the First International Congress on Pathogens at the Human-Animal Interface (ICOPHAI), Addis Ababa, Ethiopia, 15-17 September 2011.
Bisphenol A (BPA) is a chemical used to make plastics and resins. This document summarizes studies linking BPA exposure to prostate cancer risk. Animal and cell studies show BPA can disrupt cell division and centromeres, increasing abnormal cell growth. Urinary BPA levels correlate with earlier prostate cancer onset. However, human studies are needed to confirm effects, as animal results aren't always reproducible. While more research is warranted, current evidence raises concerns about BPA exposure and prostate cancer risk.
Bisphenol A (BPA) is a synthetic compound used primarily to make plastics and epoxy resins. It is found in many consumer products. There is ongoing controversy around the health effects of BPA. Some studies link BPA exposure to neurological effects, heart and kidney disease in children, breast cancer, and disrupted hormone function. However, others argue that levels of active BPA in humans are very low. While some regulatory bodies have taken action to restrict BPA, the health risks from exposure to BPA remain an area of ongoing research and debate.
Testing of neutraceuticals and food productsAbhishek Rana
Testing of neutraceuticals and food products includes Testing of microbial load, nutritional value, heavy
metals, calorific value and neutraceutical label claim test.
Brief introduction to Agmark, Bureau of Indian Standards (BIS) and Food Safety and Standards
Authority of India (FSSAI).
This document discusses lycopene, a carotenoid pigment found in tomatoes and other red fruits and vegetables. It provides lycopene's sources, history of research on it, levels of intake in different populations, content in various foods, biological activities including antioxidant effects, and potential health benefits related to reducing risks of certain cancers and cardiovascular disease. The Pennington Nutrition Series publishes research from the Pennington Biomedical Research Center on nutrition, chronic disease prevention, and healthy aging.
Bio-plastics are plastics that are either derived from renewable biomass sources like vegetable oils or are biodegradable. There are several types of bio-plastics including starch-based, cellulose-based, and aliphatic polyesters like PLA and PHA which are produced by bacteria. Compared to conventional plastics, bio-plastics have benefits like lower carbon emissions, lower toxicity, and some can biodegrade, but they also have drawbacks like higher costs and potential issues with GMOs. Bio-plastics production is growing due to advantages for certain applications and their more environmentally friendly nature.
In this slide contains need of food regulations, system and Legislation Regulation of Food Products as per BSI and Agmark.
Presented by: G. Chiranjeevi (Department of pharmaceutical analysis),
RIPER, anantapur.
Formation of polycyclic aromatic hydrocarbons in traditionally smoked fish re...ILRI
Presentation by Yolande Aké Assi, Axel Sess, Henri Godi Biégo, Mathias Koffi, Patrice Kouamé and Bassirou Bonfoh at the First International Congress on Pathogens at the Human-Animal Interface (ICOPHAI), Addis Ababa, Ethiopia, 15-17 September 2011.
Bioplastics are plastics derived from renewable biomass sources such as vegetable oils, corn starch, and pea starch rather than fossil fuels. They are designed to biodegrade and have less environmental impact than traditional plastics. Major types of bioplastics include PLA, PHA, and starch blends. While bioplastics reduce dependence on fossil fuels and hazardous waste, they remain more expensive than traditional plastics. Companies are working to lower costs and expand infrastructure to increase adoption of biodegradable alternatives.
Phthalates & their Alternatives - Health & Environmental Concerns v2zq
Phthalates & their Alternatives - Health & Environmental Concerns - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~ sustainableproduction.org
Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances in the Uni...OECD Environment
On 15 May 2019, Eeva Leinala of the OECD Environment Directorate, Sandi Moser of the Environment and Climate Change Canada, and Hannah Holsinger of the EPA presented the latest Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances undertaken by Canada and the United States.
The document discusses bioplastics and their role in sustainability. Bioplastics are either made from biological sources like plants or are biodegradable. While plastics currently make up about 225 million tons annually and are mostly non-biodegradable, bioplastics production is growing over 20% per year due to their sustainability advantages. Bioplastics can substitute for traditional plastics in packaging and other single-use products to reduce litter, or serve as durable replacements through equal or lower carbon footprints and reduced reliance on oil. Their growth will continue as brands and consumers recognize the environmental benefits of bioplastics.
This document outlines the syllabus for a course on Food Analysis & Quality Control. It covers various topics related to food quality parameters, analysis techniques, food laws and standards. The theory section covers concepts of quality control, sampling methods, physicochemical properties, sensory evaluation, food regulations, and quality systems like GMP and HACCP. The practical section involves proximate analysis, detection of adulteration, sensory analysis methods, analysis of food products and determination of contaminant residues. The overall aim is to impart knowledge and skills on evaluating and assuring food quality.
Carotenoids are organic pigments found in plants and photosynthetic bacteria that are precursors to vitamin A. They are fat-soluble tetraterpenoids produced from 8 isoprene molecules and contain 40 carbon atoms. Common carotenoids include lycopene, alpha-carotene, and beta-carotene. Carotenoids are important antioxidants and are found in foods like carrots, sweet potatoes, tomatoes, and leafy greens. Proper storage, avoidance of light and heat, and protection from oxygen are important to prevent carotenoid degradation.
The document discusses various types of bioplastics produced from biomass sources such as polysaccharides, proteins, and lipids. It provides information on the production processes and properties of starch-based, cellulose-based, chitin-based, gums-based, protein-based, and CNSL-based bioplastics. Global plastic production and waste statistics are presented. Reasons for developing bioplastics include sustainability and use of renewable resources. However, bioplastics still only account for 1% of total plastics production. Common applications of bioplastics include food packaging, food service items, and agricultural uses.
The hazardous impact of microplastics in aquatic environments calls for more scientific research to understand their occurrence, effects and mitigation strategies. This work describes the analysis of primary and secondary microplastics using FTIR and FTIR microscopy techniques.
This document provides an introduction and overview of bioplastics. It defines key terms like biodegradable, biobased, and standards for compostability. The drivers for bioplastics include being renewable, having reduced environmental impact, and addressing end-of-life disposal issues. Projections show strong growth in bioplastics production and demand over the next 5 years. While compostable bioplastics are growing, durable bioplastic applications are expected to account for nearly 40% of the market by 2011 to address performance shortcomings of compostable plastics. Emerging technologies may expand bioplastic uses in electronics and automotive industries.
In this slide contains sample preparation in LC-MS and need of sample preparation.
Presented by : P. Pavan kalyan. (Department of pharmaceutical analysis)
RIPER, anantpur.
The document outlines the agenda for Tyson Foods' Investor Day on December 10, 2014. The agenda includes welcome remarks by John Tyson, Chairman, followed by presentations on the company's financial performance and strategies for growth in key areas like innovation, brand building, and operations. There would also be a question and answer session with company leaders before the day's events conclude. Background information is provided on key speakers and lunch is to be catered by Tyson Foods' corporate chef.
Curious about low-calorie sweeteners? You’re not alone. Conflicting information about low-calorie sweeteners seems to be reaching new heights, so we’ve searched high and low for the facts. Here’s the low-down on aspartame.
Substitution of Benzotriazole UV Absorbers in PlasticsJim Botkin
Presented at the SPE Thermoplastic Elastomers TOPCON, September 2018. This paper discusses how UV-328 and other benzotriazoles came to be classified as SVHC under REACH, and identifies potentially safer substitutes for additive users based on the results of a hazard assessment.
Determination of vitamin a in the supplied sample.Atai Rabby
Vitamin A is assayed from the biological samples by high performance liquid chromatography(HPLC) method after processing and separation of samples, as the method is specific, accurate and sensitive but it is also widely measured by calorimetrically for the last many years using the maximum intensity of color developed at 620 nm by the method of Carr and price.
This document discusses different methods of food adulteration. It begins by defining food adulteration and adulterants. The main causes of food adulteration are listed as profit motive, food insecurity, urbanization, population demands, illiteracy, lack of effective food laws and government initiative. There are three main types of food adulteration: intentional, incidental, and metallic. Common methods include mixing, substitution, concealing quality, decomposed food, misbranding, and addition of toxicants. The document then provides several examples of food adulteration in developing countries and describes methods to detect common adulterants in foods like milk, sweets, oils and grains.
Bioplastics are plastic materials produced from renewable biomass sources, such as vegetable fats and oils, corn starch, straw, woodchips, sawdust, recycled food waste, etc. Bioplastic can be made from agricultural by-products and also from used plastic bottles and other containers using microorganisms.
This document summarizes recent advances in HPLC and GC techniques presented by Sajan Maharjan. It describes Ultra Performance Liquid Chromatography (UPLC) which achieves higher resolution, speed, sensitivity and separation efficiency than HPLC using columns with smaller particles (<1.7μm) and higher mobile phase pressures (>15,000psi). Two-dimensional GC (GCxGC) is discussed, which uses two columns in series with a modulator to further separate complex mixtures. A miniaturized GC system is also presented, featuring low power requirements, direct injection, portable design, and the ability to use room air as the carrier gas.
Pinene is a colorless liquid found in pine trees and other plants that gives them their characteristic scent. It exists as two isomers - alpha pinene and beta pinene. Pinene is the main component of turpentine and is obtained through the distillation of pine trees. It has several uses as an analgesic, antibacterial, and antioxidant and can also be synthesized from geranyl pyrophosphate. Derivatives of pinene include linalool and compounds used as fungicides, insecticides, and for removing heavy metals from solution. When pinene reacts with ozone it produces secondary organic aerosols that impact air quality and climate.
The drug or drug combination may not be official in any pharmacopoeias.
A proper analytical procedure for the drug may not be available in the literature due to patent regulations.
Analytical methods may not be available for the drug in the form of a formulation due to the interference caused by the formulation excipients.
Analytical methods for the quantitation of the drug in biological fluids may not be available.
Analytical methods for a drug in combination with other drugs may not be available.
The existing analytical procedures may require expensive reagents and solvents. It may also involve cumbersome extraction and separation procedures and these may not be reliable.
BIO PLASTIC a green alternative to plasticsMirza Beg
Bioplastic is presented as a green alternative to conventional plastics which are derived from petroleum. Bioplastics are derived from renewable biomass sources like vegetable oils, corn starch, and sugarcane. They are biodegradable and do not have the same negative environmental impacts as petroleum-based plastics which are not biodegradable. Common types of bioplastics include PLA, PHA, starch-based and cellulose-based plastics. While bioplastics have benefits like being renewable and reducing pollution, they also have disadvantages like using land that could grow food and being more expensive than conventional plastics.
Bisphenol A (BPA) is used to produce certain plastics and medical devices. While BPA is efficiently metabolized when ingested, its metabolism is less efficient when exposure comes from medical devices. There is debate about the health risks of BPA exposure from food and medical devices, with some studies finding specific effects from low doses but no clear conclusions. Certain medical procedures that result in prolonged exposure, like those for neonates and dialysis patients, may pose a risk since exposure could exceed the tolerable daily intake level. More information is needed on alternatives to BPA in medical devices to properly evaluate risks versus treatment benefits.
Bioplastics are plastics derived from renewable biomass sources such as vegetable oils, corn starch, and pea starch rather than fossil fuels. They are designed to biodegrade and have less environmental impact than traditional plastics. Major types of bioplastics include PLA, PHA, and starch blends. While bioplastics reduce dependence on fossil fuels and hazardous waste, they remain more expensive than traditional plastics. Companies are working to lower costs and expand infrastructure to increase adoption of biodegradable alternatives.
Phthalates & their Alternatives - Health & Environmental Concerns v2zq
Phthalates & their Alternatives - Health & Environmental Concerns - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~ sustainableproduction.org
Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances in the Uni...OECD Environment
On 15 May 2019, Eeva Leinala of the OECD Environment Directorate, Sandi Moser of the Environment and Climate Change Canada, and Hannah Holsinger of the EPA presented the latest Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances undertaken by Canada and the United States.
The document discusses bioplastics and their role in sustainability. Bioplastics are either made from biological sources like plants or are biodegradable. While plastics currently make up about 225 million tons annually and are mostly non-biodegradable, bioplastics production is growing over 20% per year due to their sustainability advantages. Bioplastics can substitute for traditional plastics in packaging and other single-use products to reduce litter, or serve as durable replacements through equal or lower carbon footprints and reduced reliance on oil. Their growth will continue as brands and consumers recognize the environmental benefits of bioplastics.
This document outlines the syllabus for a course on Food Analysis & Quality Control. It covers various topics related to food quality parameters, analysis techniques, food laws and standards. The theory section covers concepts of quality control, sampling methods, physicochemical properties, sensory evaluation, food regulations, and quality systems like GMP and HACCP. The practical section involves proximate analysis, detection of adulteration, sensory analysis methods, analysis of food products and determination of contaminant residues. The overall aim is to impart knowledge and skills on evaluating and assuring food quality.
Carotenoids are organic pigments found in plants and photosynthetic bacteria that are precursors to vitamin A. They are fat-soluble tetraterpenoids produced from 8 isoprene molecules and contain 40 carbon atoms. Common carotenoids include lycopene, alpha-carotene, and beta-carotene. Carotenoids are important antioxidants and are found in foods like carrots, sweet potatoes, tomatoes, and leafy greens. Proper storage, avoidance of light and heat, and protection from oxygen are important to prevent carotenoid degradation.
The document discusses various types of bioplastics produced from biomass sources such as polysaccharides, proteins, and lipids. It provides information on the production processes and properties of starch-based, cellulose-based, chitin-based, gums-based, protein-based, and CNSL-based bioplastics. Global plastic production and waste statistics are presented. Reasons for developing bioplastics include sustainability and use of renewable resources. However, bioplastics still only account for 1% of total plastics production. Common applications of bioplastics include food packaging, food service items, and agricultural uses.
The hazardous impact of microplastics in aquatic environments calls for more scientific research to understand their occurrence, effects and mitigation strategies. This work describes the analysis of primary and secondary microplastics using FTIR and FTIR microscopy techniques.
This document provides an introduction and overview of bioplastics. It defines key terms like biodegradable, biobased, and standards for compostability. The drivers for bioplastics include being renewable, having reduced environmental impact, and addressing end-of-life disposal issues. Projections show strong growth in bioplastics production and demand over the next 5 years. While compostable bioplastics are growing, durable bioplastic applications are expected to account for nearly 40% of the market by 2011 to address performance shortcomings of compostable plastics. Emerging technologies may expand bioplastic uses in electronics and automotive industries.
In this slide contains sample preparation in LC-MS and need of sample preparation.
Presented by : P. Pavan kalyan. (Department of pharmaceutical analysis)
RIPER, anantpur.
The document outlines the agenda for Tyson Foods' Investor Day on December 10, 2014. The agenda includes welcome remarks by John Tyson, Chairman, followed by presentations on the company's financial performance and strategies for growth in key areas like innovation, brand building, and operations. There would also be a question and answer session with company leaders before the day's events conclude. Background information is provided on key speakers and lunch is to be catered by Tyson Foods' corporate chef.
Curious about low-calorie sweeteners? You’re not alone. Conflicting information about low-calorie sweeteners seems to be reaching new heights, so we’ve searched high and low for the facts. Here’s the low-down on aspartame.
Substitution of Benzotriazole UV Absorbers in PlasticsJim Botkin
Presented at the SPE Thermoplastic Elastomers TOPCON, September 2018. This paper discusses how UV-328 and other benzotriazoles came to be classified as SVHC under REACH, and identifies potentially safer substitutes for additive users based on the results of a hazard assessment.
Determination of vitamin a in the supplied sample.Atai Rabby
Vitamin A is assayed from the biological samples by high performance liquid chromatography(HPLC) method after processing and separation of samples, as the method is specific, accurate and sensitive but it is also widely measured by calorimetrically for the last many years using the maximum intensity of color developed at 620 nm by the method of Carr and price.
This document discusses different methods of food adulteration. It begins by defining food adulteration and adulterants. The main causes of food adulteration are listed as profit motive, food insecurity, urbanization, population demands, illiteracy, lack of effective food laws and government initiative. There are three main types of food adulteration: intentional, incidental, and metallic. Common methods include mixing, substitution, concealing quality, decomposed food, misbranding, and addition of toxicants. The document then provides several examples of food adulteration in developing countries and describes methods to detect common adulterants in foods like milk, sweets, oils and grains.
Bioplastics are plastic materials produced from renewable biomass sources, such as vegetable fats and oils, corn starch, straw, woodchips, sawdust, recycled food waste, etc. Bioplastic can be made from agricultural by-products and also from used plastic bottles and other containers using microorganisms.
This document summarizes recent advances in HPLC and GC techniques presented by Sajan Maharjan. It describes Ultra Performance Liquid Chromatography (UPLC) which achieves higher resolution, speed, sensitivity and separation efficiency than HPLC using columns with smaller particles (<1.7μm) and higher mobile phase pressures (>15,000psi). Two-dimensional GC (GCxGC) is discussed, which uses two columns in series with a modulator to further separate complex mixtures. A miniaturized GC system is also presented, featuring low power requirements, direct injection, portable design, and the ability to use room air as the carrier gas.
Pinene is a colorless liquid found in pine trees and other plants that gives them their characteristic scent. It exists as two isomers - alpha pinene and beta pinene. Pinene is the main component of turpentine and is obtained through the distillation of pine trees. It has several uses as an analgesic, antibacterial, and antioxidant and can also be synthesized from geranyl pyrophosphate. Derivatives of pinene include linalool and compounds used as fungicides, insecticides, and for removing heavy metals from solution. When pinene reacts with ozone it produces secondary organic aerosols that impact air quality and climate.
The drug or drug combination may not be official in any pharmacopoeias.
A proper analytical procedure for the drug may not be available in the literature due to patent regulations.
Analytical methods may not be available for the drug in the form of a formulation due to the interference caused by the formulation excipients.
Analytical methods for the quantitation of the drug in biological fluids may not be available.
Analytical methods for a drug in combination with other drugs may not be available.
The existing analytical procedures may require expensive reagents and solvents. It may also involve cumbersome extraction and separation procedures and these may not be reliable.
BIO PLASTIC a green alternative to plasticsMirza Beg
Bioplastic is presented as a green alternative to conventional plastics which are derived from petroleum. Bioplastics are derived from renewable biomass sources like vegetable oils, corn starch, and sugarcane. They are biodegradable and do not have the same negative environmental impacts as petroleum-based plastics which are not biodegradable. Common types of bioplastics include PLA, PHA, starch-based and cellulose-based plastics. While bioplastics have benefits like being renewable and reducing pollution, they also have disadvantages like using land that could grow food and being more expensive than conventional plastics.
Bisphenol A (BPA) is used to produce certain plastics and medical devices. While BPA is efficiently metabolized when ingested, its metabolism is less efficient when exposure comes from medical devices. There is debate about the health risks of BPA exposure from food and medical devices, with some studies finding specific effects from low doses but no clear conclusions. Certain medical procedures that result in prolonged exposure, like those for neonates and dialysis patients, may pose a risk since exposure could exceed the tolerable daily intake level. More information is needed on alternatives to BPA in medical devices to properly evaluate risks versus treatment benefits.
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - CopyDr.Mohammad Alamgir
The document discusses several studies that have been conducted on the relationship between vitamins and prostate cancer. It summarizes the findings of several large studies, including the SELECT trial, ProtecT trial, and PHS II trial, which found that vitamins like selenium, vitamin E, and multivitamins did not effectively treat or prevent prostate cancer. However, it notes that the scientific community remains uncertain and more research is still needed to fully understand the complex relationship between vitamins and prostate cancer.
The Hidden Dangers Of BPA – Bisphenol ABudwig Center
BPA is a toxic endocrine-disrupting chemical that affects your hormonal system and is thought to be associated with serious diseases including breast tumors, testicular tumors, heart disease, diabetes, obesity, hyperactivity and impaired learning.
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol AChristina Parmionova
This document summarizes research on bisphenol A (BPA), a chemical used to make hard plastics and epoxy resins that is found in many food and drink packaging products. It notes that exposure to BPA is widespread, especially among infants and children, but the health effects of long-term, low-level exposure are still unclear. While some animal studies suggest potential neurological or behavioral effects, more research is needed. Federal regulators currently believe exposure levels from food packaging are safe, but some retailers have removed BPA-containing baby bottles from stores due to health concerns. The document provides additional sources for information on BPA regulations, studies and alternatives to products containing it.
Food packaging and Bisphenol A (BPA) - phthalate exposurericguer
This study evaluated the contribution of food packaging to exposure of bisphenol A (BPA) and bis(2-ethylhexyl) phthalate (DEHP) through a dietary intervention. 20 participants from 5 families were selected based on their usual consumption of canned and packaged foods. Participants provided urine samples before, during, and after a 3-day fresh foods diet that limited packaging. Urinary levels of BPA and DEHP metabolites significantly decreased during the fresh foods intervention, with BPA reduced by 66% and DEHP metabolites reduced by 53-56%. The findings suggest food packaging substantially contributes to exposure of BPA and DEHP.
The document discusses evidence-based practices in nursing related to breast cancer. It notes the increasing cases of breast cancer have posed challenges for healthcare. Treatments for breast cancer patients have been inadequate, leading to poor health outcomes. Several factors are attributed to the rise in breast cancer cases, including increased screening, lifestyle changes, hormone replacement therapy, and age. The real causes of breast cancer have not been fully established. The document then formulates a research question in PICOT format about monitoring white blood cell counts in cancer patients receiving chemotherapy at home versus at a healthcare facility.
A critical assessment of the literature surrounding EDCsTina Safavie
This document provides a summary and critique of literature surrounding endocrine disruptor compounds (EDCs). It first discusses the mechanisms by which EDCs can interfere with hormone function and their presence in various products. It then summarizes two opposing literature reviews on the effects of low doses of bisphenol A (BPA). One review by Michael Kamrin found inconsistencies in studies supporting low-dose effects, while another by vom Saal and Hughes provided evidence that low doses of BPA can harm health. The author agrees more with the latter review and critiques Kamrin's potential biases. Overall policies aim to reduce BPA exposure, and more research on EDC mechanisms and epidemiological studies is recommended.
- The document discusses concerns about the chemical BPA leaching from plastic containers into soil and being absorbed by food crops grown in those containers.
- Several experts responded that there is no clear evidence that BPA leaches into soil at levels that would be absorbed and transported through plants.
- While more research is needed, current evidence suggests growing food in plastic containers does not pose a direct danger to public health.
This document discusses the rising incidence of cancer worldwide and in India. It focuses on breast cancer incidence from a study conducted at IMS & SUM Hospital. The study found the highest incidence of breast cancer was in the 41-50 age group, and 29% of cases were young breast cancer.
The document then discusses xenoestrogens like Bisphenol A (BPA) found in plastics and their role in the development of hormone-dependent cancers like breast and prostate cancer. Laboratory experiments detected high levels of BPA in plastic water bottles and containers that were old or exposed to heat. BPA acts as a weak estrogen and is poorly removed from the body, potentially creating an estrogen-excess situation linked to
This document summarizes a presentation on the leaching of Bisphenol A (BPA) from plastic containers and its association with hormone-dependent cancers. The presenter discusses their lab findings showing high levels of BPA in water samples from scratched or weathered plastic containers. They also discuss evidence that BPA is an endocrine disruptor and weak estrogen, and may be associated with increased risks of breast cancer, prostate cancer, and other hormone-dependent cancers due to its ability to interfere with hormone signaling pathways. The presenter emphasizes the need for further research on BPA's health effects and ways to reduce human exposure through alternatives to plastic food and water containers.
The document discusses environmental endocrine disruption and its effects. It presents on the topic by Leslie Carol Botha at the AutismOne 2017 conference. Some key points made include:
- We have failed to consider the impacts of misdiagnosis and increased incidence of illness due to a more toxic environment affecting the endocrine system.
- Most people have little knowledge about the endocrine system and the diseases that can arise when it breaks down. Environmental degradation is even causing abnormal hormone responses in many women.
- Exposure to chemicals like BPA and ethinyl estradiol can cause gene expression changes in turtles' brains and alter their behaviors, indicating long-lasting effects from developmental exposure.
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38 experts on bpa panel consensus statement. effects in animals and potential...ricguer
Un conjunto de 38 prestigiados científicos de todo el mundo alertan sobre el potencial nocivo y los impactos de exposición al Bisphenol A para la salud humana.
This document discusses the challenges of communicating science related to food additives and processed foods. It summarizes presentations by the author at various conferences on topics such as the role of strategic communication, perceptions of food science, and case studies of specific additives like antioxidants, nitrites, and caffeine. The author concludes that the science alone is never enough and an expert panel is needed to clearly explain food science and defend additives and processed foods from misunderstandings.
This study examined the effects of bisphenol A (BPA) exposure on mammary cancer risk in mice. The researchers found that prenatal exposure to low and high doses of BPA led to earlier vaginal opening in female mouse offspring, indicating precocious puberty. While no differences in mammary gland development were observed, both BPA exposure groups had a statistically significant increase in susceptibility to mammary tumors induced by DMBA compared to controls. The study also found that BPA treatment promoted the growth of established MCF-7 human breast cancer tumors transplanted into mice, an effect that was reversed by tamoxifen treatment. The results suggest that BPA exposure may increase mammary cancer risk through at least two mechanisms: altering fetal mammary
The document outlines regulatory guidelines for validating traditional medicines through preclinical and clinical studies. It discusses the types of information required in investigational new drug applications (INDs) for botanical drug products, including descriptions of the botanical ingredients, manufacturing and quality controls, pharmacology, toxicity studies, and previous human experience. The level of information required increases from initial clinical trials to expanded clinical trials and approaches for new drug applications (NDAs). Preclinical studies help identify compounds likely to be safe and effective in humans, while clinical trials progress from small initial safety studies to larger efficacy trials.
Are environmental levels of bpa associated with reproductive function in fert...ricguer
Bisphenol A (BPA) is commonly found in many plastic and food packaging products. This study examined the relationship between environmental exposure to BPA, as measured in urine samples, and male reproductive health in 375 fertile men. The study found no significant associations between urinary BPA levels and semen quality measures. However, higher BPA exposure was associated with slightly lower levels of free testosterone and markers of free testosterone. While the effects seen were small, this study adds to evidence that environmental BPA exposure may impact the male endocrine system even at current exposure levels.
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) CurriculumMJDuyan
(𝐓𝐋𝐄 𝟏𝟎𝟎) (𝐋𝐞𝐬𝐬𝐨𝐧 𝟏)-𝐏𝐫𝐞𝐥𝐢𝐦𝐬
𝐃𝐢𝐬𝐜𝐮𝐬𝐬 𝐭𝐡𝐞 𝐄𝐏𝐏 𝐂𝐮𝐫𝐫𝐢𝐜𝐮𝐥𝐮𝐦 𝐢𝐧 𝐭𝐡𝐞 𝐏𝐡𝐢𝐥𝐢𝐩𝐩𝐢𝐧𝐞𝐬:
- Understand the goals and objectives of the Edukasyong Pantahanan at Pangkabuhayan (EPP) curriculum, recognizing its importance in fostering practical life skills and values among students. Students will also be able to identify the key components and subjects covered, such as agriculture, home economics, industrial arts, and information and communication technology.
𝐄𝐱𝐩𝐥𝐚𝐢𝐧 𝐭𝐡𝐞 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐧𝐝 𝐒𝐜𝐨𝐩𝐞 𝐨𝐟 𝐚𝐧 𝐄𝐧𝐭𝐫𝐞𝐩𝐫𝐞𝐧𝐞𝐮𝐫:
-Define entrepreneurship, distinguishing it from general business activities by emphasizing its focus on innovation, risk-taking, and value creation. Students will describe the characteristics and traits of successful entrepreneurs, including their roles and responsibilities, and discuss the broader economic and social impacts of entrepreneurial activities on both local and global scales.
This presentation was provided by Rebecca Benner, Ph.D., of the American Society of Anesthesiologists, for the second session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session Two: 'Expanding Pathways to Publishing Careers,' was held June 13, 2024.
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
The chapter Lifelines of National Economy in Class 10 Geography focuses on the various modes of transportation and communication that play a vital role in the economic development of a country. These lifelines are crucial for the movement of goods, services, and people, thereby connecting different regions and promoting economic activities.
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.pptHenry Hollis
The History of NZ 1870-1900.
Making of a Nation.
From the NZ Wars to Liberals,
Richard Seddon, George Grey,
Social Laboratory, New Zealand,
Confiscations, Kotahitanga, Kingitanga, Parliament, Suffrage, Repudiation, Economic Change, Agriculture, Gold Mining, Timber, Flax, Sheep, Dairying,
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
Special TechSoup offer for a free 180 days membership, and up to $150 in discounts on eligible orders.
Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"
2. What is Bisphenol A?
Bisphenol A has been in use for about fifty years in the
industrialized world.
Industrial chemical used in the production of epoxy
resins and polycarbonate plastics.
Frequently used in food and beverage containers
Inner liners of metallic food and beverage containers to
prevent corrosion
Used on thermal papers like cash register and ATM
receipts
3. Hazard Assessment: MSDS
(Sigma Aldrich)
4, 4’ – Isopropylidenediphenol (C15H16O2)
Health risk: 3* (*additional chronic hazards present)
Exposure controls:
Engineering: mechanical exhaust required
PPE: Respirator, chemical gloves, safety googles, other
protective clothing
Toxicological Information: “To the best of our knowledge, the
chemical, physical, and toxicological properties have not
been thoroughly investigated.
Environmental Information: Indication of bioaccumulation
4. Regulatory/Legal
Superfunds Amendments and Reauthorization Act,
Section 313- BPA manufacturers must submit an
annual toxic chemical release report
Listed as an irritant in the EU and US according to
MSDS
5. BPA Exposures
Primary exposure is via ingestion
BPA migrates from food/beverage containers
Migration is increased when container is heated
Other possible routes are inhalation and dermal
migration
Exposure is widespread; more than 90% of Americans
have been exposed to bisphenol a at some point.
6. Hazard Assessment: Estimated BPA
exposures (National Toxicology Program)
Population BPA micrograms/kg bw/day
Infant 0-6months formula fed 1-11
Infant 0-6months breast fed 0.2-1
Infant 6-12 months 1.65-13
Child 1.5-6 years 0.043-14.7
Adult- General Population 0.008
Adult- Occupational 0.043-100
7. Regulatory/Legal: European
Union
The EU currently has suggested a temporary tolerable
daily intake of 5μg/kg bw/day pending further study
results, a drop from the previous TDI of 50μg/kg
bw/day.
European Food Safety Administration believes health
risk for all population group is low because “estimates
for...exposure...are 3-5 times lower than the proposed t-
TDI”
8. Regulatory/Legal: United
States
No current TDI as defined by the FDA- current
assessment is that BPA is safe at “the very low levels
that occur in some foods”
Some studies have been initiated by the National
Center for Toxicological Research; findings will be
published in peer-reviewed scientific literature.
Have published a rule amending food additive
regulations to no longer provide for the use of BPA
based epoxy resins as coatings in infant formula
packaging because this use has been abandoned.
(2013)
9. Regulatory/Legal: States
California, Maine, Maryland,
Massachusetts, New York, Iowa,
Minnesota, Connecticut, and Wisconsin
have banned BPA in all baby bottles and
sippy cups.
Washington and Vermont have both
banned it in all sports bottles,
reusable food/beverage containers, as
well as baby bottles and sippy cups
Colorado vetoed House Bill 12-1174 in
February 2012, which proposed to ban
BPA in baby bottles and sippy cups.
11. Prostate Cancer
Prostate cancer is the second leading cause of cancer-
related death in U.S. men
Approximately 15% of men will be diagnosed with prostate
cancer in their lifetime
With the 1987 introduction of prostate-specific antigen
testing, the newly enhanced ability to diagnose the disease
caused incidence to spike to 240 age-adjusted cases per
100,000 men by 1992. After this “catch-up” period rates
dropped for three years, but are now back on the rise.
•Previous research has linked elevated estrogen levels during
pregnancy to increased risk of prostate cancer in males.
12. Prostate Cancer
BPA is a suspected endocrine disruptor
Acts by interfering with the biosynthesis, secretion, action
or metabolism of naturally occurring hormones.
In animal models, estrogens can drive carcinogenesis of
the prostate and have long been suspected of playing a
role in human prostate cancer
Scientists have hypothesized that prenatal exposure to
estrogen-like compounds including BPA may account
for recent increases in the rates of prostate cancer.
13. Study Published in
Public Library of Science
Focus on observations in this study – Exposure to BPA
Correlates with Early-Onset Prostate Cancer and Promotes
Centrosome Amplification and Anchorage- Independent
Growth in Vitro
Breakdown
Centrosome Amplification is when there are two or more
centromeres/centromere defect
Anchorage-Independent Growth is when cells grow
exponentially/out of control
Seemed to make use of viable scientific research methods
specific for their hypothesis
Recognized it’s limits because there are limits
14. Centromere is key to proper
cell division
Centromeres have a dynamic and
specialized functional regions
Centromere region is where sister
chromatids are attached
During mitosis/cell division spindle
poles will adhere to the centromere
region
Centromeres: Chromosomal
Regions Essential to Mitosis/Cell
Division
17. Study Hypothesizes
Urinary BPA levels may be associated with prostate cancer
and may have a prognostic value
BPA exposure can disrupt mitosis/cell division; specifically
affecting the centromere region causing some cells to have
improper coding
Proposed that if there is exposure early in life to an
estrogenic compound- BPA- it may reprograms stem cells
Proposed this study could be an addition to the growing field
of epigenetics, linking this chemical to altered DNA in
fetuses and the potential for later life disease
18. Limits within the study
Research was done with cell based model studies and
cannot be extrapolated to humans
Data observed should not be considered conclusive but
rather seen as preliminary findings
Obviously, important to replicate study results and
ultimately long term human studies need to be done
19. Observed Effects on
Centromere Regions
Numbers of centromeres were scored using
fluorescence microscopy
Observed increase in abnormal centromeres in cells
exposed to the BPA
Conclusion
Low doses of BPA promoted centrosome
amplification/altering of the centromere and causing
adverse effects thus may play a long term role in
prostate carcinogenesis
20. Urinary BPA Levels May show Correlation
with Prostate Cancer
Stratified analyses showed
the association between
urinary BPA levels and
Prostate Cancer was highly
significant among patients <
65 and that it was not
significant for those >65.
Perplexing and at face value this suggests that higher BPA exposure
is associated with earlier onset of Prostate Cancer.
However, based on theory of epigenetics the findings do raise the
possibility of early life reprogramming of prostate cancer in humans
21. BPA Exposure correlated with Prostate
Carcinogenesis
Chronic BPA exposure
promotes independent
abnormal growth in cells
Representative of colonies
after 2 weeks incubation
Cells with the BPA exposure
formed larger colonies
compared with those grown
in absence of BPA
22. American Chemistry Council
News Release
For Immediate Release - Washington (Jan. 6, 2014)
STUDY CLAIMING INCREASED PROSTATE CANCER
RISK FROM BPA EXPOSURE IS NOT SUPPORTED
BY RELIABLE HUMAN EXPOSURE DATA
“The weight of scientific evidence on BPA has been
extensively evaluated by government and scientific
bodies around the world, which have declared it safe
as used in food contact materials.”
23. Concerns Observed in the
Available Research
The effects of low-dose exposure to BPA in lab animals
(done in determining affect on estrogen levels) are not
always reproducible.
Need to exercise caution when extrapolating these findings
to humans; the study was derived from animal studies and
cell based models.
How could an analogous study on men be done?
To obtain results of early exposure to BPA and it’s relation to
prostate cancer would take 50 plus years
More research is needed- but does this justify holding out on
a ban on BPA?
24. References
Bienkowski, Brian. "BPA Exposure Linked to Prostate Cancer." Scientific American Global
RSS. N.p., n.d. Web. 7 Apr. 2014. <http://www.scientificamerican.com/article/bpa-exposure-
linked-to-prostate-cancer/>.
"Bisphenol A." EFSA Topic:. N.p., n.d. Web. 7 Apr. 2014.
<http://www.efsa.europa.eu/en/topics/topic/bisphenol.htm>.
"Bisphenol A (BPA) Action Plan Summary | Existing Chemicals | OPPT | US EPA." EPA.
Environmental Protection Agency, n.d. Web. 6 Apr. 2014.
<http://www.epa.gov/oppt/existingchemicals/pubs/actionplans/bpa.html>.
"Bisphenol A Action Plan." EPA Existing Chemicals. N.p., n.d. Web. 29 Mar. 2010.
<http://www.epa.gov/oppt/existingchemicals/pubs/actionplans/bpa_action_plan.pdf>.
"Bisphenol-A." Toxics in Our Lives:. N.p., n.d. Web. 7 Apr. 2014.
<http://www.saferstates.com/toxics_in_our_lives/chemicals_of_concern/BPA.html>.
"Colorado lawmaker proposes BPAÂ ban." KDVRcom. N.p., n.d. Web. 7 Apr. 2014.
<http://kdvr.com/2012/02/20/colorado-lawmaker-proposes-bpa-ban/>.
"Exposure to Bisphenol A Correlates with Early-Onset Prostate Cancer and Promotes
Centrosome Amplification and Anchorage-Independent Growth In Vitro." PLOS DOI:
10.1371/journal.pone.0090332 (2014): 1-8. Print.
25. References
"Food." FDA Regulations No Longer Authorize the Use of BPA in Infant Formula Packaging
Based on Abandonment; Decision Not Based on Safety. N.p., n.d. Web. 7 Apr. 2014.
<http://www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm360147.htm>.
"Google." Google. N.p., n.d. Web. 6 Apr. 2014.
<http://www.google.com/search?client=safari&rls=en&q=lowdosepeerfinalrpt-2.pdf&ie=UTF-
8&oe=UTF-8>.
"News & Events." Bisphenol A (BPA): Use in Food Contact Application. N.p., n.d. Web. 7 Apr.
2014. <http://www.fda.gov/newsevents/publichealthfocus/ucm064437.htm>.
"Oncocytic Renal Neoplasms A Molecular Approach To A Common ...." Eureka Alert. N.p., n.d.
Web. 7 Apr. 2014. <http://www.readanybook.com/oncocytic-renal-neoplasms-a-molecular-
approach-to-a-common-diagnostic-challenge-famonzon-et-all-pathology-case-reviews-2010-
pdf-i226647>.
"Prostate Cancer Risk From BPA Exposure Is Not Supported By Reliable Human Exposure
Data." Prostate Cancer Risk From BPA Exposure Is Not Supported By Reliable Human
Exposure Data. N.p., n.d. Web. 7 Apr. 2014.
<http://www.americanchemistry.com/media/pressreleasestranscripts/acc-news-
releases/prostate-cancer-risk-from-bpa-exposure-is-not-supported-by-reliable-human-exposure-
data.html>.