SlideShare a Scribd company logo
Health and
Food Safety
Bisphenol A in medical devices
Is exposure to BPA through the use of medical devices
safe for humans?
Bisphenol A (BPA)
is used to pro-
duce certain
plastics such as
polycarbonates
a n d   e p o x y
resins. Most
p e o p l e   a r e
exposed to it
through food,
because BPA
is used in
food packaging.
BPA is also used in the production
of polymers for medical devices such as
catheters and implants, and some dental
devices. Is exposure to BPA via medical
devices safe? Are there any risks?
 What happens to BPA once it is in
the body?
When BPA is ingested, it is absorbed by the
digestive system and efficiently metabolized
by the liver into a non-toxic product that
goes into the bloodstream. It is then quickly
filtered out by the kidneys into the urine.
When BPA comes into the body through the
use of medical devices, such as catheters
or polymer materials used for hemodialysis
equipment, the efficiency of the metabolism
to form a non-toxic metabolite is lower. But,
its elimination is also relatively fast, so that
BPA is not able to accumulate in the body.
 What are the health risks from
exposure to BPA through food and
via medical devices?
There is an ongoing debate in the scientific
community as to how much BPA people are
exposed to and what its effects on health
might be.
Many studies on the effects of BPA on health
show that there is no significant risk at
the actual level of exposure through food,
but there are some other studies showing
specific effects at low doses. For example,
BPA shows hormone-like effects at relatively
high doses, but there are some experimental
data suggesting that BPA might have similar
effects also at very low doses. BPA might
also have specific effects on the metabolism
and weight gain, on the development of
mammary glands and on behavior and
anxiety. But the findings about these effects
remain controversial. So far, there are no
clear conclusions from available and ongoing
research.
For its risk assessment of BPA in medical
devices, the SCENIHR took as reference point
the temporary tolerable daily intake derived
by EFSA, which is 4 μg per kg of body weight
per day. The SCENIHR considers this an
appropriate basis for evaluating the risk from
BPA exposure via medical devices.
 Examples of medical devices made
with BPA
BPA is a key building block of some plastics
or derivates used in a range of medical
applications such as adhesives and sealants
used in dentistry, neonatal care incubators,
hemodialysers and cardiopulmonary bypass
machines.
The risk of BPA exposure from medical
devices is associated with the release of
BPA from these devices. The actual level of
exposure has been investigated for various
use scenarios. In most of these applications,
including use in dentistry, the amount of
BPA people are exposed to is deemed safe,
because it does not exceed the limit of the
tolerable daily intake of 4 μg per kg body
weight per day. Moreover, exposure to BPA
through medical devices is usually only for a
short period of time, while the tolerable daily
intake assumes lifelong, continuous daily
exposure.
 Are there applications where
there is a risk from exposure to
BPA?
The highest estimated exposure to
BPA occurs during prolonged medical
procedures especially for neonates
in intensive care units, for infants
undergoing  prolonged  medical
procedures and for dialysis patients.
Based on the available data, the
SCENIHR concludes that risk of
adverse effects from BPA might exist
in such cases, since the exposure
exceeds the reference value and the
exposed population can be particularly
vulnerable.
 Should BPA be banned from
medical devices?
The benefit of medical devices should
also be taken into account: e.g. the
survival of premature infants often
depends on them. The possibility of
finding alternatives for BPA-containing
materials needs to be evaluated in
terms of effectiveness of the treatment
as well as of potential toxicity of the
alternatives. This is something that
is not yet possible because there is
not enough information on potential
alternative material.
This opinion is available at:
http://ec.europa.eu/health/scientific_
committees/emerging/opinions/index_
en.htm
This fact sheet is based on the
opinion of the independent Scientific
Committee on Emerging and Newly
Identified Health Risks (SCENIHR) on
“The safety of the use of bisphenol A
in medical devices". February, 2015

More Related Content

Similar to Bisphenol A in medical devices

Bpa presentation
Bpa presentationBpa presentation
Bpa presentation
Angie Moss
 
BPA
BPABPA
Bisphenol a
Bisphenol aBisphenol a
Bisphenol a
Susanta Das
 
Bisphenol a.
Bisphenol a.Bisphenol a.
Bisphenol a.
Mahmoud Farouk
 
Bisphenol a 2
Bisphenol a 2Bisphenol a 2
Bisphenol a 2
khalidjasser
 
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol AHealth Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
Christina Parmionova
 
Can food crops be grown safely in plastic containers
Can food crops be grown safely in plastic containersCan food crops be grown safely in plastic containers
Can food crops be grown safely in plastic containers
Prof. Dr. Willem Van Cotthem
 
What Are Probiotics from SmartBiotics
What Are Probiotics from SmartBioticsWhat Are Probiotics from SmartBiotics
What Are Probiotics from SmartBiotics
Smart Biotics
 
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
ricguer
 
An evaluation of evidence for the carcinogenic activity of bpa
An evaluation of evidence for the carcinogenic activity of bpaAn evaluation of evidence for the carcinogenic activity of bpa
An evaluation of evidence for the carcinogenic activity of bpa
ricguer
 
A Review on Current Solid Oral Pediatrics Dosage Forms.pptx
A Review on Current Solid Oral Pediatrics Dosage Forms.pptxA Review on Current Solid Oral Pediatrics Dosage Forms.pptx
A Review on Current Solid Oral Pediatrics Dosage Forms.pptx
ZerlealemTsegaye2
 
Fetal exposure to bisphenol a as risk factor for the childhood asthma
Fetal exposure to bisphenol a as risk factor for the childhood asthmaFetal exposure to bisphenol a as risk factor for the childhood asthma
Fetal exposure to bisphenol a as risk factor for the childhood asthma
ricguer
 
People Safe: The Link Between Declining Fertility & Environmental Contami...
People Safe: The Link Between Declining Fertility & Environmental Contami...People Safe: The Link Between Declining Fertility & Environmental Contami...
People Safe: The Link Between Declining Fertility & Environmental Contami...
abowes23
 
Endocrine disruptorspresentation
Endocrine disruptorspresentationEndocrine disruptorspresentation
Endocrine disruptorspresentation
Beverly Hills
 
Impact of bpa exposure on behavior in children
Impact of bpa exposure on behavior in childrenImpact of bpa exposure on behavior in children
Impact of bpa exposure on behavior in children
ricguer
 
Our own story-Pathetic polythene
Our own story-Pathetic polytheneOur own story-Pathetic polythene
Our own story-Pathetic polythene
Prof Viyatprajna Acharya
 
Contamination in milk/ Source of contamination in milk
Contamination in milk/ Source of contamination in milkContamination in milk/ Source of contamination in milk
Contamination in milk/ Source of contamination in milk
J Roopavathy
 
Introduction to Detox 360
Introduction to Detox 360Introduction to Detox 360
Introduction to Detox 360
Dr Nancy Doreo, DC
 
Biowaivers
Biowaivers Biowaivers
Yogurt and fermented milks in daily nutrition: from science to the guidelines...
Yogurt and fermented milks in daily nutrition: from science to the guidelines...Yogurt and fermented milks in daily nutrition: from science to the guidelines...
Yogurt and fermented milks in daily nutrition: from science to the guidelines...
Yogurt in Nutrition #YINI
 

Similar to Bisphenol A in medical devices (20)

Bpa presentation
Bpa presentationBpa presentation
Bpa presentation
 
BPA
BPABPA
BPA
 
Bisphenol a
Bisphenol aBisphenol a
Bisphenol a
 
Bisphenol a.
Bisphenol a.Bisphenol a.
Bisphenol a.
 
Bisphenol a 2
Bisphenol a 2Bisphenol a 2
Bisphenol a 2
 
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol AHealth Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
Health Safety Of Plastics Used For Food And Drinking Water Packaging Bisphenol A
 
Can food crops be grown safely in plastic containers
Can food crops be grown safely in plastic containersCan food crops be grown safely in plastic containers
Can food crops be grown safely in plastic containers
 
What Are Probiotics from SmartBiotics
What Are Probiotics from SmartBioticsWhat Are Probiotics from SmartBiotics
What Are Probiotics from SmartBiotics
 
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
Urine Bisphenol A (BPA) level in relation to obseity and overweight ins schoo...
 
An evaluation of evidence for the carcinogenic activity of bpa
An evaluation of evidence for the carcinogenic activity of bpaAn evaluation of evidence for the carcinogenic activity of bpa
An evaluation of evidence for the carcinogenic activity of bpa
 
A Review on Current Solid Oral Pediatrics Dosage Forms.pptx
A Review on Current Solid Oral Pediatrics Dosage Forms.pptxA Review on Current Solid Oral Pediatrics Dosage Forms.pptx
A Review on Current Solid Oral Pediatrics Dosage Forms.pptx
 
Fetal exposure to bisphenol a as risk factor for the childhood asthma
Fetal exposure to bisphenol a as risk factor for the childhood asthmaFetal exposure to bisphenol a as risk factor for the childhood asthma
Fetal exposure to bisphenol a as risk factor for the childhood asthma
 
People Safe: The Link Between Declining Fertility & Environmental Contami...
People Safe: The Link Between Declining Fertility & Environmental Contami...People Safe: The Link Between Declining Fertility & Environmental Contami...
People Safe: The Link Between Declining Fertility & Environmental Contami...
 
Endocrine disruptorspresentation
Endocrine disruptorspresentationEndocrine disruptorspresentation
Endocrine disruptorspresentation
 
Impact of bpa exposure on behavior in children
Impact of bpa exposure on behavior in childrenImpact of bpa exposure on behavior in children
Impact of bpa exposure on behavior in children
 
Our own story-Pathetic polythene
Our own story-Pathetic polytheneOur own story-Pathetic polythene
Our own story-Pathetic polythene
 
Contamination in milk/ Source of contamination in milk
Contamination in milk/ Source of contamination in milkContamination in milk/ Source of contamination in milk
Contamination in milk/ Source of contamination in milk
 
Introduction to Detox 360
Introduction to Detox 360Introduction to Detox 360
Introduction to Detox 360
 
Biowaivers
Biowaivers Biowaivers
Biowaivers
 
Yogurt and fermented milks in daily nutrition: from science to the guidelines...
Yogurt and fermented milks in daily nutrition: from science to the guidelines...Yogurt and fermented milks in daily nutrition: from science to the guidelines...
Yogurt and fermented milks in daily nutrition: from science to the guidelines...
 

More from GreenFacts

Biologie de synthèse
Biologie de synthèseBiologie de synthèse
Biologie de synthèse
GreenFacts
 
Biología sintética
Biología sintéticaBiología sintética
Biología sintética
GreenFacts
 
Synthetic biology
Synthetic biologySynthetic biology
Synthetic biology
GreenFacts
 
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
GreenFacts
 
¿Son seguros los cosméticos que contienen sílice en nanoforma?
¿Son seguros los cosméticos que contienen sílice en nanoforma?¿Son seguros los cosméticos que contienen sílice en nanoforma?
¿Son seguros los cosméticos que contienen sílice en nanoforma?
GreenFacts
 
Les produits d’obturation dentaire sont-ils sans danger ?
Les produits d’obturation dentaire sont-ils sans danger ?Les produits d’obturation dentaire sont-ils sans danger ?
Les produits d’obturation dentaire sont-ils sans danger ?
GreenFacts
 
¿Son seguras las obturaciones dentales?
¿Son seguras las obturaciones dentales?¿Son seguras las obturaciones dentales?
¿Son seguras las obturaciones dentales?
GreenFacts
 
Are dental fillings safe?
Are dental fillings safe?Are dental fillings safe?
Are dental fillings safe?
GreenFacts
 
Le bisphénol A dans les appareils médicaux
Le bisphénol A dans les appareils médicauxLe bisphénol A dans les appareils médicaux
Le bisphénol A dans les appareils médicaux
GreenFacts
 
Bisphenol A in Medizinprodukten
Bisphenol A in MedizinproduktenBisphenol A in Medizinprodukten
Bisphenol A in Medizinprodukten
GreenFacts
 
Bisfenol A en dispositivos médicos
Bisfenol A en dispositivos médicosBisfenol A en dispositivos médicos
Bisfenol A en dispositivos médicos
GreenFacts
 
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
GreenFacts
 
Climate Change mitigation: practical measures to limit global warming IPCC re...
Climate Change mitigation: practical measures to limit global warming IPCC re...Climate Change mitigation: practical measures to limit global warming IPCC re...
Climate Change mitigation: practical measures to limit global warming IPCC re...
GreenFacts
 
The essentials about vaccines and vaccination
The essentials about vaccines and vaccinationThe essentials about vaccines and vaccination
The essentials about vaccines and vaccination
GreenFacts
 
Antibiotic resistance: causes, consequences and means to limit it
Antibiotic resistance: causes, consequences and means to limit itAntibiotic resistance: causes, consequences and means to limit it
Antibiotic resistance: causes, consequences and means to limit it
GreenFacts
 
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
GreenFacts
 
Sunscreens with titanium dioxide as nanoparticles. Health risks?
Sunscreens with titanium dioxide as nanoparticles. Health risks?Sunscreens with titanium dioxide as nanoparticles. Health risks?
Sunscreens with titanium dioxide as nanoparticles. Health risks?
GreenFacts
 
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
GreenFacts
 
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
GreenFacts
 
Les nanoparticules d’argent sont-elles sûres ?
Les nanoparticules d’argent sont-elles sûres ?Les nanoparticules d’argent sont-elles sûres ?
Les nanoparticules d’argent sont-elles sûres ?
GreenFacts
 

More from GreenFacts (20)

Biologie de synthèse
Biologie de synthèseBiologie de synthèse
Biologie de synthèse
 
Biología sintética
Biología sintéticaBiología sintética
Biología sintética
 
Synthetic biology
Synthetic biologySynthetic biology
Synthetic biology
 
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
L’utilisation de cosmétiques contenant de la silice sous forme nano est-elle ...
 
¿Son seguros los cosméticos que contienen sílice en nanoforma?
¿Son seguros los cosméticos que contienen sílice en nanoforma?¿Son seguros los cosméticos que contienen sílice en nanoforma?
¿Son seguros los cosméticos que contienen sílice en nanoforma?
 
Les produits d’obturation dentaire sont-ils sans danger ?
Les produits d’obturation dentaire sont-ils sans danger ?Les produits d’obturation dentaire sont-ils sans danger ?
Les produits d’obturation dentaire sont-ils sans danger ?
 
¿Son seguras las obturaciones dentales?
¿Son seguras las obturaciones dentales?¿Son seguras las obturaciones dentales?
¿Son seguras las obturaciones dentales?
 
Are dental fillings safe?
Are dental fillings safe?Are dental fillings safe?
Are dental fillings safe?
 
Le bisphénol A dans les appareils médicaux
Le bisphénol A dans les appareils médicauxLe bisphénol A dans les appareils médicaux
Le bisphénol A dans les appareils médicaux
 
Bisphenol A in Medizinprodukten
Bisphenol A in MedizinproduktenBisphenol A in Medizinprodukten
Bisphenol A in Medizinprodukten
 
Bisfenol A en dispositivos médicos
Bisfenol A en dispositivos médicosBisfenol A en dispositivos médicos
Bisfenol A en dispositivos médicos
 
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
L’exposition aux champs électromagnétiques est-elle dangereuse pour la santé ?
 
Climate Change mitigation: practical measures to limit global warming IPCC re...
Climate Change mitigation: practical measures to limit global warming IPCC re...Climate Change mitigation: practical measures to limit global warming IPCC re...
Climate Change mitigation: practical measures to limit global warming IPCC re...
 
The essentials about vaccines and vaccination
The essentials about vaccines and vaccinationThe essentials about vaccines and vaccination
The essentials about vaccines and vaccination
 
Antibiotic resistance: causes, consequences and means to limit it
Antibiotic resistance: causes, consequences and means to limit itAntibiotic resistance: causes, consequences and means to limit it
Antibiotic resistance: causes, consequences and means to limit it
 
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
Protectores solares con dióxido de titanio en forma de nanopartículas. ¿Un ri...
 
Sunscreens with titanium dioxide as nanoparticles. Health risks?
Sunscreens with titanium dioxide as nanoparticles. Health risks?Sunscreens with titanium dioxide as nanoparticles. Health risks?
Sunscreens with titanium dioxide as nanoparticles. Health risks?
 
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
Sonnenschutzmittel mit Titandioxid in Nanopartikelform. Gesundheitsrisiken?
 
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
Produits solaires avec des nanoparticules de dioxyde de titane. Des risques p...
 
Les nanoparticules d’argent sont-elles sûres ?
Les nanoparticules d’argent sont-elles sûres ?Les nanoparticules d’argent sont-elles sûres ?
Les nanoparticules d’argent sont-elles sûres ?
 

Recently uploaded

HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
Rommel Luis III Israel
 
TheHistroke 340B Program Solutions | TheHistroke
TheHistroke 340B Program Solutions | TheHistrokeTheHistroke 340B Program Solutions | TheHistroke
TheHistroke 340B Program Solutions | TheHistroke
TheHistroke
 
M2ComSys - BPO - RCM Services Profile - 2022.pptx
M2ComSys - BPO - RCM Services Profile - 2022.pptxM2ComSys - BPO - RCM Services Profile - 2022.pptx
M2ComSys - BPO - RCM Services Profile - 2022.pptx
josemonk
 
HEALTH ASSESSMENT-BREAST AND AXILLA.pptx
HEALTH ASSESSMENT-BREAST AND AXILLA.pptxHEALTH ASSESSMENT-BREAST AND AXILLA.pptx
HEALTH ASSESSMENT-BREAST AND AXILLA.pptx
Rommel Luis III Israel
 
VITAMINS(referred as a Organic compound)
VITAMINS(referred as a Organic compound)VITAMINS(referred as a Organic compound)
VITAMINS(referred as a Organic compound)
saloniswain225
 
TheHistroke 340B Product Presentation_MetaBridge
TheHistroke 340B Product Presentation_MetaBridgeTheHistroke 340B Product Presentation_MetaBridge
TheHistroke 340B Product Presentation_MetaBridge
TheHistroke
 
OT Dude's Salary Survey Report July 2024.pdf
OT Dude's Salary Survey Report July 2024.pdfOT Dude's Salary Survey Report July 2024.pdf
OT Dude's Salary Survey Report July 2024.pdf
OTDUDE
 
care plan2.docx (mental health nursing )
care plan2.docx (mental health nursing )care plan2.docx (mental health nursing )
care plan2.docx (mental health nursing )
Karishma Rajput
 
Keratoconus & it’s management (kunj).pptx
Keratoconus & it’s management (kunj).pptxKeratoconus & it’s management (kunj).pptx
Keratoconus & it’s management (kunj).pptx
Kunj Vihari
 
Yogic Sukshma Vyayama Teacher Training Course
Yogic Sukshma Vyayama Teacher Training CourseYogic Sukshma Vyayama Teacher Training Course
Yogic Sukshma Vyayama Teacher Training Course
Karuna Yoga Vidya Peetham
 
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptxRevolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
ALMAGIA INTERNATIONAL
 
Role of Physiotherapy management in lumbar canal stenosis.
Role of Physiotherapy management in lumbar canal stenosis.Role of Physiotherapy management in lumbar canal stenosis.
Role of Physiotherapy management in lumbar canal stenosis.
Anjali Rana
 
disease condition seen in adolescent girl " ANEMIA"
disease condition seen in adolescent girl " ANEMIA"disease condition seen in adolescent girl " ANEMIA"
disease condition seen in adolescent girl " ANEMIA"
purvipatel517209
 
Diagnosis and treatment planning in complete denture.pptx
Diagnosis and treatment planning in complete denture.pptxDiagnosis and treatment planning in complete denture.pptx
Diagnosis and treatment planning in complete denture.pptx
SatvikaPrasad
 
How dental support group work...........
How dental support group work...........How dental support group work...........
How dental support group work...........
AvilasDentalGroup
 
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate CourseYoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
Karuna Yoga Vidya Peetham
 
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
Levi Shapiro
 
Teaching Methodology of Hatha Yoga Teacher Training Course.pptx
Teaching Methodology of Hatha Yoga Teacher Training Course.pptxTeaching Methodology of Hatha Yoga Teacher Training Course.pptx
Teaching Methodology of Hatha Yoga Teacher Training Course.pptx
Karuna Yoga Vidya Peetham
 
WHO PPCs for therapeutic HPV vaccines_June2024.pdf
WHO PPCs for therapeutic HPV vaccines_June2024.pdfWHO PPCs for therapeutic HPV vaccines_June2024.pdf
WHO PPCs for therapeutic HPV vaccines_June2024.pdf
anabakhtar
 
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
The Lifesciences Magazine
 

Recently uploaded (20)

HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
HEALTH ASSESSMENT IN NURSING - ABDOMEN (2)
 
TheHistroke 340B Program Solutions | TheHistroke
TheHistroke 340B Program Solutions | TheHistrokeTheHistroke 340B Program Solutions | TheHistroke
TheHistroke 340B Program Solutions | TheHistroke
 
M2ComSys - BPO - RCM Services Profile - 2022.pptx
M2ComSys - BPO - RCM Services Profile - 2022.pptxM2ComSys - BPO - RCM Services Profile - 2022.pptx
M2ComSys - BPO - RCM Services Profile - 2022.pptx
 
HEALTH ASSESSMENT-BREAST AND AXILLA.pptx
HEALTH ASSESSMENT-BREAST AND AXILLA.pptxHEALTH ASSESSMENT-BREAST AND AXILLA.pptx
HEALTH ASSESSMENT-BREAST AND AXILLA.pptx
 
VITAMINS(referred as a Organic compound)
VITAMINS(referred as a Organic compound)VITAMINS(referred as a Organic compound)
VITAMINS(referred as a Organic compound)
 
TheHistroke 340B Product Presentation_MetaBridge
TheHistroke 340B Product Presentation_MetaBridgeTheHistroke 340B Product Presentation_MetaBridge
TheHistroke 340B Product Presentation_MetaBridge
 
OT Dude's Salary Survey Report July 2024.pdf
OT Dude's Salary Survey Report July 2024.pdfOT Dude's Salary Survey Report July 2024.pdf
OT Dude's Salary Survey Report July 2024.pdf
 
care plan2.docx (mental health nursing )
care plan2.docx (mental health nursing )care plan2.docx (mental health nursing )
care plan2.docx (mental health nursing )
 
Keratoconus & it’s management (kunj).pptx
Keratoconus & it’s management (kunj).pptxKeratoconus & it’s management (kunj).pptx
Keratoconus & it’s management (kunj).pptx
 
Yogic Sukshma Vyayama Teacher Training Course
Yogic Sukshma Vyayama Teacher Training CourseYogic Sukshma Vyayama Teacher Training Course
Yogic Sukshma Vyayama Teacher Training Course
 
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptxRevolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
Revolutionize Pain Management with Almagia’s PEMF Devices Shop Now.pptx
 
Role of Physiotherapy management in lumbar canal stenosis.
Role of Physiotherapy management in lumbar canal stenosis.Role of Physiotherapy management in lumbar canal stenosis.
Role of Physiotherapy management in lumbar canal stenosis.
 
disease condition seen in adolescent girl " ANEMIA"
disease condition seen in adolescent girl " ANEMIA"disease condition seen in adolescent girl " ANEMIA"
disease condition seen in adolescent girl " ANEMIA"
 
Diagnosis and treatment planning in complete denture.pptx
Diagnosis and treatment planning in complete denture.pptxDiagnosis and treatment planning in complete denture.pptx
Diagnosis and treatment planning in complete denture.pptx
 
How dental support group work...........
How dental support group work...........How dental support group work...........
How dental support group work...........
 
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate CourseYoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
Yoga Philosophy Lifestyle , ethics Teacher Training Certificate Course
 
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
Reimbursement Bootcamp- Coding, Coverage & Payment lecture by David Farber, K...
 
Teaching Methodology of Hatha Yoga Teacher Training Course.pptx
Teaching Methodology of Hatha Yoga Teacher Training Course.pptxTeaching Methodology of Hatha Yoga Teacher Training Course.pptx
Teaching Methodology of Hatha Yoga Teacher Training Course.pptx
 
WHO PPCs for therapeutic HPV vaccines_June2024.pdf
WHO PPCs for therapeutic HPV vaccines_June2024.pdfWHO PPCs for therapeutic HPV vaccines_June2024.pdf
WHO PPCs for therapeutic HPV vaccines_June2024.pdf
 
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
Automated Feedback in Digital Depression Screening: DISCOVER Trial | The Life...
 

Bisphenol A in medical devices

  • 1. Health and Food Safety Bisphenol A in medical devices Is exposure to BPA through the use of medical devices safe for humans? Bisphenol A (BPA) is used to pro- duce certain plastics such as polycarbonates a n d   e p o x y resins. Most p e o p l e   a r e exposed to it through food, because BPA is used in food packaging. BPA is also used in the production of polymers for medical devices such as catheters and implants, and some dental devices. Is exposure to BPA via medical devices safe? Are there any risks?  What happens to BPA once it is in the body? When BPA is ingested, it is absorbed by the digestive system and efficiently metabolized by the liver into a non-toxic product that goes into the bloodstream. It is then quickly filtered out by the kidneys into the urine. When BPA comes into the body through the use of medical devices, such as catheters or polymer materials used for hemodialysis equipment, the efficiency of the metabolism to form a non-toxic metabolite is lower. But, its elimination is also relatively fast, so that BPA is not able to accumulate in the body.  What are the health risks from exposure to BPA through food and via medical devices? There is an ongoing debate in the scientific community as to how much BPA people are exposed to and what its effects on health might be. Many studies on the effects of BPA on health show that there is no significant risk at the actual level of exposure through food, but there are some other studies showing specific effects at low doses. For example, BPA shows hormone-like effects at relatively high doses, but there are some experimental data suggesting that BPA might have similar effects also at very low doses. BPA might also have specific effects on the metabolism and weight gain, on the development of mammary glands and on behavior and anxiety. But the findings about these effects remain controversial. So far, there are no clear conclusions from available and ongoing research. For its risk assessment of BPA in medical devices, the SCENIHR took as reference point the temporary tolerable daily intake derived by EFSA, which is 4 μg per kg of body weight per day. The SCENIHR considers this an appropriate basis for evaluating the risk from BPA exposure via medical devices.  Examples of medical devices made with BPA BPA is a key building block of some plastics or derivates used in a range of medical applications such as adhesives and sealants used in dentistry, neonatal care incubators, hemodialysers and cardiopulmonary bypass machines. The risk of BPA exposure from medical devices is associated with the release of BPA from these devices. The actual level of exposure has been investigated for various use scenarios. In most of these applications, including use in dentistry, the amount of BPA people are exposed to is deemed safe, because it does not exceed the limit of the tolerable daily intake of 4 μg per kg body weight per day. Moreover, exposure to BPA through medical devices is usually only for a short period of time, while the tolerable daily intake assumes lifelong, continuous daily exposure.  Are there applications where there is a risk from exposure to BPA? The highest estimated exposure to BPA occurs during prolonged medical procedures especially for neonates in intensive care units, for infants undergoing  prolonged  medical procedures and for dialysis patients. Based on the available data, the SCENIHR concludes that risk of adverse effects from BPA might exist in such cases, since the exposure exceeds the reference value and the exposed population can be particularly vulnerable.  Should BPA be banned from medical devices? The benefit of medical devices should also be taken into account: e.g. the survival of premature infants often depends on them. The possibility of finding alternatives for BPA-containing materials needs to be evaluated in terms of effectiveness of the treatment as well as of potential toxicity of the alternatives. This is something that is not yet possible because there is not enough information on potential alternative material. This opinion is available at: http://ec.europa.eu/health/scientific_ committees/emerging/opinions/index_ en.htm This fact sheet is based on the opinion of the independent Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) on “The safety of the use of bisphenol A in medical devices". February, 2015