Analysis

                                                   Table 1

                               Anti-A Serum        Anti-B Serum        Anti-Rh Serum          Blood Type
  Slide 1- Mr. Smith              cloudy               Clear               cloudy                 A
   Slide 2- Mr. Jones              clear              cloudy                clear                 B
  Slide 3- Mr. Green              cloudy              cloudy               cloudy                AB
  Slide 4- Ms. Brown               clear               clear                clear                 O
               1) Choose one of the following patients:

                      a) Mr. Smith, Mr. Jones, Mr. Green, Ms. Brown= A, B, AB, O

                      b) Using the information shown in Figure 1 on Blood type and the data recorded in
                          Table 1, Whatagglutinogens are present on the patient’s RBC’s? The type of
                          agglutinogens in each blood type depends on the person. Mr. Smith has A
                          agglutinogens and anti-B agglutinins, Mr. Jones has B agglutinogens and anti-A
                          agglutinins, Mr. Green has A & B agglutinogens, but NO agglutinins, and Ms.
                          Brown NO agglutinogens and anti-A and anti-B agglutinins.

                      c) What ABO agglutinin(s) is/are found in the patient’s Plasma? Answered above.

                      d) What is the patient’s blood type? Mr. Smith is type A, Mr. Jones is type B, Mr.
                          Green is type AB, and Ms. Brown is type O.

                      e) If this patient needed a transfusion, what blood type(s) could this patient safely
                           receive? Type A can receive blood from type A and O, type B can receive blood
                           from type B and O, type AB can receive from A, B, AB, and O, and type O can
                           receive from only O.

                      f) What blood type(s) could safely receive this patient’s blood? Answered above.

               2) Below is the information representing the blood type analysis of a new patient
                   (patient X). From the information obtained, fill out the medical technologist report.

A: Agglutination               Medical technologist’s report

B: No Agglutination                  ABO Type: A

Rh: Agglutination                    Rh Type: positive

               3) Compare and Contrast agglutinogens and agglutinins. In the diagram show at least 2
                   similarities and 2 differences.
Agglutinogens                                           Agglutinins

                    Differences                                 Similarities             Differences

       Stimulates production of agglutinins            Found in only some blood types Actual substance

the particulate antigen used in agglutination tests.     Part of the immune system   Causes coagulation



                4) Pretend you went with your class on a medical career field trip to a local hospital. One
                    of the stops on the visit was to the hospital’s blood lab. The medical technologist at
                    this stop gave a demonstration of how blood types are determined. Your job is to
                    write a paragraph for the school newspaper on the visit to the blood lab,
                    summarizing what you’ve learned about how ABO/Rh blood groups are determined.
                    Write a paragraph and include the title.

                    Blood type is determined by if blood aggulates or doesn’t. A doctor would draw a
                    patients blood. After drawing the patients blood the doctor would go to the lab and
                    put 3 drops of blood in 3 separte holes. The doctor would then put anti-a serum in
                    one hole, anit-b in another and anti-Rh in the last. He would stir up the blood and
                    serum together and see what happens to the blood. If the blood is clumby and clear
                    and isn’t very liquidy it has aggulated. If one of the anti serums matches with the Rh
                    then that determines the blood type. For example if the hole where the doctor
                    inserted the anti-a serum and the hole with the anti-Rh are both cloudy and non
                    agglution then the blood type is A. to determin if its positive or negative you look at
                    the Rh hole. If its agglunation/ clumpy its positive. If its not and its cloudy and
                    liquidyits negative.

                5) List at least 3 situations where blood typing could be used.

                    a) for blood transfusions

                    b) organ transplant

                    c)to know your chances to have certain diseases

                6) Define ErythroblastosisFetalis. severe anemia in newborn babies; the result of Rh
                    incompatibility between maternal and fetal blood.

                    a) Describe the sequence of events that lead to this condition. typically occurs
                        when the child of an Rh-negative mother inherits Rh-positive blood from
                        the father; can be diagnosed before birth by amniocentesis

                    b) What might be some benefits if the medical profession developed a shot or
                        vaccination that could desensitize an Rh+ situation? No more
                        erythroblastosisfetalis

                7) You are a type Aeryhthorocyte placing an ad in the personals and you are seeking a
                    compatible mate for a long lasting transfusion. Create an ad to be submitted to the
                    newspaper.
Erythrocyte trying to find someone who enjoys diffusion of oxygen and carbon dioxide.
    I’m more of a Type A red blood erythrocyte, its okay if you don’t have a nucleus!



8) Another important diagnostic tool used by medical technologist is determining a
    patient’s blood cell count, for both red blood cells and white blood cells. When this
    procedure is performed, one technique used is to take multiple samples and
    calculate the average. This method of multiple sampling is a standard procedure in
    scientific and medical investigations. Discuss why this method is important in blood
    typing. Being able to figure out how many red blood cells a person has because if a
    person is making too many red blood cells or too little both can be very dangerous
    and its good to have a tool that can see how many cells a person has to be able to
    figure out why one person has this disease or something similar to that.

9) Each year thousands of people contract blood borne diseases. What could be done in
    a clinical blood lab to minimize the risk of obtaining or spreading a blood borne
    disease? It is very important that all the blood be tested before it is transfused. The
    equipment must also be sterile. The procedures used should also be very carefully
    reviewed and well known by the medical professionals handling the blood and the
    transfusion. All patients should be aware of the risks and know when proper
    procedures are being used and when they are not so that they can be advocates of
    their own safety.

10) In a short paragraph, identify what you think may be the next important
    breakthrough, milestone or discovery in the study of blood and blood diseases and
    explain why. Being able to make real blood. Every year americans donate tons and
    tons of blood to save those who need blood from either loosing a bunch of it or
    need extra blood when undergoing a surgery. If scientist could make real blood that
    a patient could use it would be the same as a person donating their and this could
    save money for hospitals on supplies for blood donations and such.

Blood type lab questions

  • 1.
    Analysis Table 1 Anti-A Serum Anti-B Serum Anti-Rh Serum Blood Type Slide 1- Mr. Smith cloudy Clear cloudy A Slide 2- Mr. Jones clear cloudy clear B Slide 3- Mr. Green cloudy cloudy cloudy AB Slide 4- Ms. Brown clear clear clear O 1) Choose one of the following patients: a) Mr. Smith, Mr. Jones, Mr. Green, Ms. Brown= A, B, AB, O b) Using the information shown in Figure 1 on Blood type and the data recorded in Table 1, Whatagglutinogens are present on the patient’s RBC’s? The type of agglutinogens in each blood type depends on the person. Mr. Smith has A agglutinogens and anti-B agglutinins, Mr. Jones has B agglutinogens and anti-A agglutinins, Mr. Green has A & B agglutinogens, but NO agglutinins, and Ms. Brown NO agglutinogens and anti-A and anti-B agglutinins. c) What ABO agglutinin(s) is/are found in the patient’s Plasma? Answered above. d) What is the patient’s blood type? Mr. Smith is type A, Mr. Jones is type B, Mr. Green is type AB, and Ms. Brown is type O. e) If this patient needed a transfusion, what blood type(s) could this patient safely receive? Type A can receive blood from type A and O, type B can receive blood from type B and O, type AB can receive from A, B, AB, and O, and type O can receive from only O. f) What blood type(s) could safely receive this patient’s blood? Answered above. 2) Below is the information representing the blood type analysis of a new patient (patient X). From the information obtained, fill out the medical technologist report. A: Agglutination Medical technologist’s report B: No Agglutination ABO Type: A Rh: Agglutination Rh Type: positive 3) Compare and Contrast agglutinogens and agglutinins. In the diagram show at least 2 similarities and 2 differences.
  • 2.
    Agglutinogens Agglutinins Differences Similarities Differences Stimulates production of agglutinins Found in only some blood types Actual substance the particulate antigen used in agglutination tests. Part of the immune system Causes coagulation 4) Pretend you went with your class on a medical career field trip to a local hospital. One of the stops on the visit was to the hospital’s blood lab. The medical technologist at this stop gave a demonstration of how blood types are determined. Your job is to write a paragraph for the school newspaper on the visit to the blood lab, summarizing what you’ve learned about how ABO/Rh blood groups are determined. Write a paragraph and include the title. Blood type is determined by if blood aggulates or doesn’t. A doctor would draw a patients blood. After drawing the patients blood the doctor would go to the lab and put 3 drops of blood in 3 separte holes. The doctor would then put anti-a serum in one hole, anit-b in another and anti-Rh in the last. He would stir up the blood and serum together and see what happens to the blood. If the blood is clumby and clear and isn’t very liquidy it has aggulated. If one of the anti serums matches with the Rh then that determines the blood type. For example if the hole where the doctor inserted the anti-a serum and the hole with the anti-Rh are both cloudy and non agglution then the blood type is A. to determin if its positive or negative you look at the Rh hole. If its agglunation/ clumpy its positive. If its not and its cloudy and liquidyits negative. 5) List at least 3 situations where blood typing could be used. a) for blood transfusions b) organ transplant c)to know your chances to have certain diseases 6) Define ErythroblastosisFetalis. severe anemia in newborn babies; the result of Rh incompatibility between maternal and fetal blood. a) Describe the sequence of events that lead to this condition. typically occurs when the child of an Rh-negative mother inherits Rh-positive blood from the father; can be diagnosed before birth by amniocentesis b) What might be some benefits if the medical profession developed a shot or vaccination that could desensitize an Rh+ situation? No more erythroblastosisfetalis 7) You are a type Aeryhthorocyte placing an ad in the personals and you are seeking a compatible mate for a long lasting transfusion. Create an ad to be submitted to the newspaper.
  • 3.
    Erythrocyte trying tofind someone who enjoys diffusion of oxygen and carbon dioxide. I’m more of a Type A red blood erythrocyte, its okay if you don’t have a nucleus! 8) Another important diagnostic tool used by medical technologist is determining a patient’s blood cell count, for both red blood cells and white blood cells. When this procedure is performed, one technique used is to take multiple samples and calculate the average. This method of multiple sampling is a standard procedure in scientific and medical investigations. Discuss why this method is important in blood typing. Being able to figure out how many red blood cells a person has because if a person is making too many red blood cells or too little both can be very dangerous and its good to have a tool that can see how many cells a person has to be able to figure out why one person has this disease or something similar to that. 9) Each year thousands of people contract blood borne diseases. What could be done in a clinical blood lab to minimize the risk of obtaining or spreading a blood borne disease? It is very important that all the blood be tested before it is transfused. The equipment must also be sterile. The procedures used should also be very carefully reviewed and well known by the medical professionals handling the blood and the transfusion. All patients should be aware of the risks and know when proper procedures are being used and when they are not so that they can be advocates of their own safety. 10) In a short paragraph, identify what you think may be the next important breakthrough, milestone or discovery in the study of blood and blood diseases and explain why. Being able to make real blood. Every year americans donate tons and tons of blood to save those who need blood from either loosing a bunch of it or need extra blood when undergoing a surgery. If scientist could make real blood that a patient could use it would be the same as a person donating their and this could save money for hospitals on supplies for blood donations and such.