This document discusses blood pressure measurement and hypertension. It provides guidelines for proper blood pressure measurement technique and defines thresholds for diagnosing and treating hypertension. It also discusses the use of ambulatory blood pressure monitoring and home blood pressure monitoring to improve diagnosis and management of hypertension. High blood pressure is a major risk factor for heart disease and stroke.
this is a detailed study on blood pressure measurement on clinical watching , methods , equipment's , common problems ,and all major aspects of blood pressure measurement is mentioned in detail .
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The cardiac cycle consists of relaxation (diastole) and contraction (systole) of the heart. Each cycle begins with an electrical impulse from the sinus node which causes atrial contraction and is recorded as the P wave on an ECG. Contraction of the ventricles follows, recorded as the QRS complex, pumping blood into the arteries. Ventricular relaxation is recorded as the T wave. The heart's pumping is regulated intrinsically via the Frank-Starling mechanism and extrinsically by the autonomic nervous system.
The document contains information about labeling the parts of the heart and the cardiac output. It defines cardiac output as the amount of blood pumped by the heart per minute, which is calculated by multiplying heart rate by stroke volume. It then provides an example calculation of a person's cardiac output. The document also describes the conduction system of the heart, noting that the sinoatrial node acts as the pacemaker and the atrioventricular node relays electrical impulses to allow for coordinated contraction of the atria and ventricles.
The document discusses heart sounds, describing the four main sounds - S1, S2, S3, and S4. S1 occurs with the closing of the atrioventricular valves, coinciding with the R wave of an ECG. S2 occurs with the closing of the semilunar valves, coinciding with the T wave. S3 occurs during rapid ventricular filling between the T and P waves. S4 occurs during atrial systole between the P wave and Q wave. Heart sounds provide diagnostic value for assessing cardiac diseases and can be studied using a stethoscope, microphone, or phonocardiogram.
Arterial Pulse: Radial
To assess cardiac function. To assess state of health.
NEW BLOGSITE ADDRESS:
"Nurses Information Site"
http://nursesinfosite.blogspot.com
ECG- Atrial Fibrillation, CXR-P/A view-Cardiomegaly,
Echocardiogram-severe mitral stenosis with severe MR with
moderate pulmonary hypertension. Patient underwent MVR and
she is doing well.
The coronary circulation consists of the arterial supply, venous drainage and lymphatic drainage of the heart. The heart receives its blood supply from the right and left coronary arteries. The right coronary artery supplies the right atrium and ventricle while the left coronary artery supplies the left atrium and ventricle. Coronary blood flow is regulated by physical, chemical, neural and hormonal factors to meet the metabolic demands of the heart. Coronary artery disease can lead to conditions like angina pectoris and myocardial infarction due to reduced blood supply to the heart muscle.
The document discusses drugs commonly used in cardiac catheterization laboratories. It describes the uses, mechanisms of action, dosages, and side effects of various drugs including lidocaine for local anesthesia, heparin and glycoprotein IIb/IIIa inhibitors for anticoagulation during procedures like percutaneous coronary intervention, nitrates like glyceryl trinitrate for vasodilation, inotropes like dopamine and dobutamine, antiarrhythmics like amiodarone, and contrast agents like iohexol. The document provides an overview of how these drugs are utilized during different cardiac procedures performed in cath labs.
this is a detailed study on blood pressure measurement on clinical watching , methods , equipment's , common problems ,and all major aspects of blood pressure measurement is mentioned in detail .
please comment
thank you
The cardiac cycle consists of relaxation (diastole) and contraction (systole) of the heart. Each cycle begins with an electrical impulse from the sinus node which causes atrial contraction and is recorded as the P wave on an ECG. Contraction of the ventricles follows, recorded as the QRS complex, pumping blood into the arteries. Ventricular relaxation is recorded as the T wave. The heart's pumping is regulated intrinsically via the Frank-Starling mechanism and extrinsically by the autonomic nervous system.
The document contains information about labeling the parts of the heart and the cardiac output. It defines cardiac output as the amount of blood pumped by the heart per minute, which is calculated by multiplying heart rate by stroke volume. It then provides an example calculation of a person's cardiac output. The document also describes the conduction system of the heart, noting that the sinoatrial node acts as the pacemaker and the atrioventricular node relays electrical impulses to allow for coordinated contraction of the atria and ventricles.
The document discusses heart sounds, describing the four main sounds - S1, S2, S3, and S4. S1 occurs with the closing of the atrioventricular valves, coinciding with the R wave of an ECG. S2 occurs with the closing of the semilunar valves, coinciding with the T wave. S3 occurs during rapid ventricular filling between the T and P waves. S4 occurs during atrial systole between the P wave and Q wave. Heart sounds provide diagnostic value for assessing cardiac diseases and can be studied using a stethoscope, microphone, or phonocardiogram.
Arterial Pulse: Radial
To assess cardiac function. To assess state of health.
NEW BLOGSITE ADDRESS:
"Nurses Information Site"
http://nursesinfosite.blogspot.com
ECG- Atrial Fibrillation, CXR-P/A view-Cardiomegaly,
Echocardiogram-severe mitral stenosis with severe MR with
moderate pulmonary hypertension. Patient underwent MVR and
she is doing well.
The coronary circulation consists of the arterial supply, venous drainage and lymphatic drainage of the heart. The heart receives its blood supply from the right and left coronary arteries. The right coronary artery supplies the right atrium and ventricle while the left coronary artery supplies the left atrium and ventricle. Coronary blood flow is regulated by physical, chemical, neural and hormonal factors to meet the metabolic demands of the heart. Coronary artery disease can lead to conditions like angina pectoris and myocardial infarction due to reduced blood supply to the heart muscle.
The document discusses drugs commonly used in cardiac catheterization laboratories. It describes the uses, mechanisms of action, dosages, and side effects of various drugs including lidocaine for local anesthesia, heparin and glycoprotein IIb/IIIa inhibitors for anticoagulation during procedures like percutaneous coronary intervention, nitrates like glyceryl trinitrate for vasodilation, inotropes like dopamine and dobutamine, antiarrhythmics like amiodarone, and contrast agents like iohexol. The document provides an overview of how these drugs are utilized during different cardiac procedures performed in cath labs.
Normal arterial blood pressure ranges from 90-140/60-90 mmHg. Systolic pressure is the maximum pressure when blood is ejected from the heart, while diastolic is the minimum pressure when the heart is resting between beats. Mean arterial pressure, which averages 93 mmHg, is the main driving force for blood flow. Blood pressure is regulated through short term mechanisms like baroreceptor and chemoreceptor reflexes which control heart rate and vascular tone, and long term factors like blood volume and vessel elasticity. Strict control of blood pressure is important to ensure adequate blood flow to vital organs.
The heart is a hollow muscular pump located in the chest cavity. It pumps blood through the circulatory system around the body. The left side pumps oxygenated blood through the arteries while the right side pumps deoxygenated blood to the lungs. On average, the heart beats over 2.5 billion times in a lifetime, pumping over 5,000 liters of blood per year. The heart is protected by membranes and surrounded by fluid within the pericardium. It has four chambers - two upper atria which receive blood and two lower ventricles which pump blood out. Blood flows through the heart via valves which ensure one-way flow.
This document discusses the concepts of blood pressure including systolic, diastolic, and mean arterial pressure. It defines normal blood pressure ranges and factors that can influence blood pressure such as age, sex, body size, emotions, exercise, meals, sleep, and gravity. The relationship between cardiac output, total peripheral resistance, and blood pressure is explained. Mechanisms for short-term blood pressure regulation including baroreceptor reflex, chemoreceptor reflex, and central nervous system ischemic response are outlined. Long-term regulation involves the kidneys, renin-angiotensin system, and pressure natriuresis.
Baroreceptors And Negative Feedback MechanismSulav Shrestha
Baroreceptors are mechanoreceptors located in the carotid arteries and aorta that detect changes in blood pressure. As part of a negative feedback system called the baroreflex, baroreceptors send signals to the brain to increase or decrease heart rate and vascular resistance to maintain normal blood pressure. When blood pressure rises, baroreceptors inhibit the vasomotor center of the brain to decrease sympathetic nervous system activity and lower blood pressure. Conversely, lower blood pressure activates the vasomotor center to increase sympathetic activity and raise blood pressure. In addition to short term regulation, baroreceptors can reset over days to the new blood pressure level in cases of chronic high blood pressure.
The document provides an overview of electrocardiography (ECG/EKG) including: defining ECG and describing the heart's conduction system; explaining that ECG interpretation involves pattern recognition of waves like the P, QRS, and T waves associated with electrical activity in the heart's chambers; and outlining how ECGs are recorded by placing electrodes on the body and analyzing the resulting traces in various leads to evaluate the heart's rhythm, rate, intervals, and for any abnormalities.
The coronary circulation refers to the blood vessels that supply and drain the heart. The heart receives its blood supply from two coronary arteries - the left and right coronary arteries. The left coronary artery supplies the left side of the heart including parts of the left atrium and ventricle. It branches into the anterior interventricular artery and circumflex artery. The right coronary artery supplies the right side of the heart and parts of the left side. It has branches like the right marginal artery and posterior interventricular artery. Deoxygenated blood from the heart drains into the coronary sinus and other cardiac veins before emptying into the right atrium.
An ECG is a recording of the electrical activity of the heart over time using skin electrodes. It is the gold standard for diagnosing cardiac diseases in a noninvasive manner. The ECG records the P wave from atrial depolarization, the QRS complex from ventricular depolarization and repolarization of the atria, and the T wave from ventricular repolarization. Proper electrode placement and ensuring good skin contact is important for obtaining an accurate recording. The recording is then analyzed based on heart rate, rhythm, intervals, wave amplitudes and shapes to identify any abnormalities.
The document discusses electrical activity of the heart as recorded by an electrocardiogram (ECG). It defines key ECG terminology like waves, intervals, complexes and explains what each part of the ECG represents in terms of electrical activity in the heart. Specific waves like P, QRS, T are described in detail along with common abnormalities. Other concepts covered include heart rate calculation methods, cardiac rhythms and axis determination. The document provides a comprehensive overview of interpreting and understanding ECG readings.
Heart sounds are produced during the cardiac cycle by the mechanical activities of the heart, including the flow of blood through chambers, contraction of cardiac muscle, and closure of heart valves. There are four main heart sounds - the first, second, third, and fourth. The first and second sounds are the most prominent, known as the "lub-dub" sounds, and occur during ventricular contraction and relaxation. The third sound is softer and occurs during ventricular filling, while the fourth is usually inaudible but may be heard in pathological conditions. Studying heart sounds has diagnostic value as changes can indicate cardiac valve diseases.
The right and left coronary arteries originate from the right and left sinuses of the aortic root. The right coronary artery supplies the right ventricle while the left coronary artery supplies the anterior portion of the ventricular septum and left ventricle. The left main coronary artery bifurcates into the left anterior descending artery and left circumflex artery. The left anterior descending artery supplies the majority of the left ventricle while the left circumflex artery supplies the left ventricle free wall. In approximately 70% of cases, the right coronary artery is the dominant artery supplying the posterior portions of the heart.
This document discusses cardiac output and its measurement. It defines cardiac output as the amount of blood ejected by each ventricle per minute, which is calculated as stroke volume multiplied by heart rate. It describes several methods to measure cardiac output, including the indicator dye dilution method, thermodilution, and measurement of inhaled inert gases. It discusses factors that can cause cardiac output to vary, such as age, sex, environmental temperature, exercise, and various pathological conditions.
The cardiac conduction system sends signals through specialized cardiac muscle cells to coordinate the rhythmic contraction of the heart. It includes the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers. The sinoatrial node acts as the pacemaker by spontaneously generating electrical impulses that spread through the internodal pathways and cause the atria to contract. The impulse then travels to and through the atrioventricular node and bundle of His before reaching the Purkinje fibers, which trigger fast, coordinated ventricular contraction.
The document discusses the valves of the heart. There are two types of valves - atrioventricular valves and semilunar valves.
The atrioventricular valves include the tricuspid valve between the right atrium and ventricle, and the mitral/bicuspid valve between the left atrium and ventricle.
The semilunar valves include the pulmonary valve between the right ventricle and pulmonary artery, and the aortic valve between the left ventricle and aorta. Each valve has specific roles in regulating blood flow and preventing backflow through the heart chambers and vessels.
Prevention and treatment of heart diseaseshanikrupa
Shanikrupaheartcare is the best hospital to cure all types of heart disease. Shanikrupaheartcare also helps to Avoid bypass surgery in India we are proving this treatments in Pune, India.
Our AIM is non surgical cardiac treatment where we use 3 Dimentional Cardiovascular Cartography for diagnosis of disease & Arterial Clearance Therapy / chelation therapy & EECP therapy for the treatment of the heart disease.
This document provides information on examining the cardiovascular system. It discusses the anatomy of the heart and describes how to examine jugular venous pressure. A normal jugular venous pressure is less than 8 cm above the right atrium. The document outlines the steps to measure jugular venous pressure including inspecting the internal jugular vein and measuring the highest point of pulsation in relation to the sternal angle. Elevated jugular venous pressure indicates abnormal cardiac function or pressures in the right heart.
Arterial pulse (The Guyton and Hall Physiology)Maryam Fida
The arterial pulse is caused by the pressure wave that travels along the walls of the arteries when blood is ejected from the left ventricle into the aorta. As the aorta expands to accommodate the ejected blood volume, its elastic recoil causes the pressure wave. This pressure wave causes the expansion of the arterial wall, which can be felt as the arterial pulse. The velocity of the pressure wave is much faster than blood flow. Pulse pressure depends on factors like stroke volume, elasticity of arteries, and the character of blood ejection from the left ventricle. Examining the arterial pulse provides information about heart rate, rhythm, and can help diagnose diseases.
The heart is pyramidal in shape with an apex pointing leftward and downward. It has four chambers - two atria which receive blood and two ventricles which pump blood. The right atrium receives deoxygenated blood from the body and pumps it to the right ventricle to be sent to the lungs. The left atrium receives oxygenated blood from the lungs and pumps it to the left ventricle to be sent to the body. Blood flows through the heart via the tricuspid, bicuspid/mitral, pulmonary and aortic valves. The heart's conduction system coordinates contractions and is composed of the sinoatrial node, atrioventricular node and bundle of His.
Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels. It is typically measured in millimeters of mercury (mmHg). Normal blood pressure is less than 120/80 mmHg. Blood pressure is regulated through both immediate mechanisms like baroreceptor reflexes and delayed mechanisms involving the kidneys, renin-angiotensin system, and other hormones. Factors that affect blood pressure include cardiac output, peripheral resistance, blood volume, vessel elasticity, and viscosity. Hypertension is defined as high blood pressure over 140/90 mmHg and can increase the risk of heart disease and stroke if left untreated.
Normal arterial blood pressure ranges from 90-140/60-90 mmHg. Systolic pressure is the maximum pressure when blood is ejected from the heart, while diastolic is the minimum pressure when the heart is resting between beats. Mean arterial pressure, which averages 93 mmHg, is the main driving force for blood flow. Blood pressure is regulated through short term mechanisms like baroreceptor and chemoreceptor reflexes which control heart rate and vascular tone, and long term factors like blood volume and vessel elasticity. Strict control of blood pressure is important to ensure adequate blood flow to vital organs.
The heart is a hollow muscular pump located in the chest cavity. It pumps blood through the circulatory system around the body. The left side pumps oxygenated blood through the arteries while the right side pumps deoxygenated blood to the lungs. On average, the heart beats over 2.5 billion times in a lifetime, pumping over 5,000 liters of blood per year. The heart is protected by membranes and surrounded by fluid within the pericardium. It has four chambers - two upper atria which receive blood and two lower ventricles which pump blood out. Blood flows through the heart via valves which ensure one-way flow.
This document discusses the concepts of blood pressure including systolic, diastolic, and mean arterial pressure. It defines normal blood pressure ranges and factors that can influence blood pressure such as age, sex, body size, emotions, exercise, meals, sleep, and gravity. The relationship between cardiac output, total peripheral resistance, and blood pressure is explained. Mechanisms for short-term blood pressure regulation including baroreceptor reflex, chemoreceptor reflex, and central nervous system ischemic response are outlined. Long-term regulation involves the kidneys, renin-angiotensin system, and pressure natriuresis.
Baroreceptors And Negative Feedback MechanismSulav Shrestha
Baroreceptors are mechanoreceptors located in the carotid arteries and aorta that detect changes in blood pressure. As part of a negative feedback system called the baroreflex, baroreceptors send signals to the brain to increase or decrease heart rate and vascular resistance to maintain normal blood pressure. When blood pressure rises, baroreceptors inhibit the vasomotor center of the brain to decrease sympathetic nervous system activity and lower blood pressure. Conversely, lower blood pressure activates the vasomotor center to increase sympathetic activity and raise blood pressure. In addition to short term regulation, baroreceptors can reset over days to the new blood pressure level in cases of chronic high blood pressure.
The document provides an overview of electrocardiography (ECG/EKG) including: defining ECG and describing the heart's conduction system; explaining that ECG interpretation involves pattern recognition of waves like the P, QRS, and T waves associated with electrical activity in the heart's chambers; and outlining how ECGs are recorded by placing electrodes on the body and analyzing the resulting traces in various leads to evaluate the heart's rhythm, rate, intervals, and for any abnormalities.
The coronary circulation refers to the blood vessels that supply and drain the heart. The heart receives its blood supply from two coronary arteries - the left and right coronary arteries. The left coronary artery supplies the left side of the heart including parts of the left atrium and ventricle. It branches into the anterior interventricular artery and circumflex artery. The right coronary artery supplies the right side of the heart and parts of the left side. It has branches like the right marginal artery and posterior interventricular artery. Deoxygenated blood from the heart drains into the coronary sinus and other cardiac veins before emptying into the right atrium.
An ECG is a recording of the electrical activity of the heart over time using skin electrodes. It is the gold standard for diagnosing cardiac diseases in a noninvasive manner. The ECG records the P wave from atrial depolarization, the QRS complex from ventricular depolarization and repolarization of the atria, and the T wave from ventricular repolarization. Proper electrode placement and ensuring good skin contact is important for obtaining an accurate recording. The recording is then analyzed based on heart rate, rhythm, intervals, wave amplitudes and shapes to identify any abnormalities.
The document discusses electrical activity of the heart as recorded by an electrocardiogram (ECG). It defines key ECG terminology like waves, intervals, complexes and explains what each part of the ECG represents in terms of electrical activity in the heart. Specific waves like P, QRS, T are described in detail along with common abnormalities. Other concepts covered include heart rate calculation methods, cardiac rhythms and axis determination. The document provides a comprehensive overview of interpreting and understanding ECG readings.
Heart sounds are produced during the cardiac cycle by the mechanical activities of the heart, including the flow of blood through chambers, contraction of cardiac muscle, and closure of heart valves. There are four main heart sounds - the first, second, third, and fourth. The first and second sounds are the most prominent, known as the "lub-dub" sounds, and occur during ventricular contraction and relaxation. The third sound is softer and occurs during ventricular filling, while the fourth is usually inaudible but may be heard in pathological conditions. Studying heart sounds has diagnostic value as changes can indicate cardiac valve diseases.
The right and left coronary arteries originate from the right and left sinuses of the aortic root. The right coronary artery supplies the right ventricle while the left coronary artery supplies the anterior portion of the ventricular septum and left ventricle. The left main coronary artery bifurcates into the left anterior descending artery and left circumflex artery. The left anterior descending artery supplies the majority of the left ventricle while the left circumflex artery supplies the left ventricle free wall. In approximately 70% of cases, the right coronary artery is the dominant artery supplying the posterior portions of the heart.
This document discusses cardiac output and its measurement. It defines cardiac output as the amount of blood ejected by each ventricle per minute, which is calculated as stroke volume multiplied by heart rate. It describes several methods to measure cardiac output, including the indicator dye dilution method, thermodilution, and measurement of inhaled inert gases. It discusses factors that can cause cardiac output to vary, such as age, sex, environmental temperature, exercise, and various pathological conditions.
The cardiac conduction system sends signals through specialized cardiac muscle cells to coordinate the rhythmic contraction of the heart. It includes the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers. The sinoatrial node acts as the pacemaker by spontaneously generating electrical impulses that spread through the internodal pathways and cause the atria to contract. The impulse then travels to and through the atrioventricular node and bundle of His before reaching the Purkinje fibers, which trigger fast, coordinated ventricular contraction.
The document discusses the valves of the heart. There are two types of valves - atrioventricular valves and semilunar valves.
The atrioventricular valves include the tricuspid valve between the right atrium and ventricle, and the mitral/bicuspid valve between the left atrium and ventricle.
The semilunar valves include the pulmonary valve between the right ventricle and pulmonary artery, and the aortic valve between the left ventricle and aorta. Each valve has specific roles in regulating blood flow and preventing backflow through the heart chambers and vessels.
Prevention and treatment of heart diseaseshanikrupa
Shanikrupaheartcare is the best hospital to cure all types of heart disease. Shanikrupaheartcare also helps to Avoid bypass surgery in India we are proving this treatments in Pune, India.
Our AIM is non surgical cardiac treatment where we use 3 Dimentional Cardiovascular Cartography for diagnosis of disease & Arterial Clearance Therapy / chelation therapy & EECP therapy for the treatment of the heart disease.
This document provides information on examining the cardiovascular system. It discusses the anatomy of the heart and describes how to examine jugular venous pressure. A normal jugular venous pressure is less than 8 cm above the right atrium. The document outlines the steps to measure jugular venous pressure including inspecting the internal jugular vein and measuring the highest point of pulsation in relation to the sternal angle. Elevated jugular venous pressure indicates abnormal cardiac function or pressures in the right heart.
Arterial pulse (The Guyton and Hall Physiology)Maryam Fida
The arterial pulse is caused by the pressure wave that travels along the walls of the arteries when blood is ejected from the left ventricle into the aorta. As the aorta expands to accommodate the ejected blood volume, its elastic recoil causes the pressure wave. This pressure wave causes the expansion of the arterial wall, which can be felt as the arterial pulse. The velocity of the pressure wave is much faster than blood flow. Pulse pressure depends on factors like stroke volume, elasticity of arteries, and the character of blood ejection from the left ventricle. Examining the arterial pulse provides information about heart rate, rhythm, and can help diagnose diseases.
The heart is pyramidal in shape with an apex pointing leftward and downward. It has four chambers - two atria which receive blood and two ventricles which pump blood. The right atrium receives deoxygenated blood from the body and pumps it to the right ventricle to be sent to the lungs. The left atrium receives oxygenated blood from the lungs and pumps it to the left ventricle to be sent to the body. Blood flows through the heart via the tricuspid, bicuspid/mitral, pulmonary and aortic valves. The heart's conduction system coordinates contractions and is composed of the sinoatrial node, atrioventricular node and bundle of His.
Blood pressure is the pressure exerted by circulating blood on the walls of blood vessels. It is typically measured in millimeters of mercury (mmHg). Normal blood pressure is less than 120/80 mmHg. Blood pressure is regulated through both immediate mechanisms like baroreceptor reflexes and delayed mechanisms involving the kidneys, renin-angiotensin system, and other hormones. Factors that affect blood pressure include cardiac output, peripheral resistance, blood volume, vessel elasticity, and viscosity. Hypertension is defined as high blood pressure over 140/90 mmHg and can increase the risk of heart disease and stroke if left untreated.
There are four main mechanisms that regulate blood pressure: nervous, renal, hormonal, and local. The nervous mechanism acts the fastest via the vasomotor system to control heart rate and vasoconstriction/vasodilation in response to baroreceptors and chemoreceptors. The renal mechanism regulates blood pressure long-term by controlling extracellular fluid volume and through the renin-angiotensin system. Hormonal and local factors also contribute to blood pressure regulation.
Here are the steps to measure blood pressure using different types of sphygmomanometers:
1. Aeroid (mercurial and non-mercurial) sphygmomanometer:
- Attach the cuff to the upper arm and pump the bulb until the column of mercury rises to 200 mmHg.
- Slowly release the pressure and listen over the brachial artery with a stethoscope. Note the first appearance and disappearance of Korotkoff sounds.
2. Anaeroid (automatic) sphygmomanometer:
- Turn on the device and make sure it is functioning properly. Select the appropriate cuff size.
- Apply the cuff to the upper arm and press start. The c
Short-term regulation of blood pressure involves nervous and chemical mechanisms that act within seconds or minutes to control blood pressure. The nervous system regulates blood pressure by changing blood vessel diameter and heart rate through the sympathetic and parasympathetic nervous systems. Baroreceptors in the carotid sinus and aortic arch detect changes in blood pressure and stimulate reflex responses to return blood pressure to normal levels. Chemoreceptors sense oxygen and carbon dioxide levels and stimulate responses to maintain proper gas exchange in the lungs and tissues. If blood pressure drops severely, the brain triggers a central nervous system ischemic response to rapidly constrict blood vessels and raise blood pressure.
This slide summarize all the ways to measure the blood pressure in an very easy manner.This slide specially explains all invasive methods of blood pressure measurement with real world images and examples.
This document summarizes blood pressure, including defining it as the lateral pressure exerted by flowing blood on artery walls. It discusses types of blood pressure depending on the blood vessel, normal ranges, measurement methods, factors that affect blood pressure both physiologically and pathologically, complications of hypertension, and mechanisms that regulate arterial blood pressure over rapid, intermediate, and long term timescales.
This document discusses blood pressure measurement and hypotension/hypertension. It provides details on:
- Accurately measuring blood pressure is important for assessing and managing hypotension and diagnosing/treating hypertension.
- Hypotension occurs when blood pressure is lower than usual, which can lead to inadequate blood flow. Postural hypotension is a type of hypotension that happens when changing positions.
- Hypertension is considered present if blood pressure is at or above 140/90 mmHg. Long-term high blood pressure can damage organs.
- The document outlines techniques for properly measuring blood pressure using a sphygmomanometer and stethoscope. Listening for Korotkoff sounds helps determine systolic
This document discusses key issues in blood pressure measurement, including the choice of measuring device, subject posture, cuff size, and protocol standardization. It notes that mercury sphygmomanometers were traditionally considered the gold standard but are now restricted for sale, while automated devices are commonly used but can lack comparability. Proper training and standardization of measurement protocols are important for accurate blood pressure measurement regardless of the device used.
This is a presentation of our final year project of Biomedical Engineering course on Cuffless blood pressure monitoring. A new technology recently developed. We have tried to develop a model for the same.
This document discusses the clinical relevance and prognostic significance of morning surge in blood pressure in patients with hypertension. It begins by defining different dipping patterns seen in ambulatory blood pressure monitoring, including dippers, extreme dippers, non-dippers, and risers. It then reviews evidence from several long-term studies showing that non-dipping and morning surge are associated with increased cardiovascular risk. The document discusses factors that influence dipping status and examines differences in effects of antihypertensive drug classes on daytime and nighttime blood pressure. It emphasizes the importance of controlling morning blood pressure surge and maintaining normal circadian rhythm patterns.
2 solutions for noninvasive blood pressure measurementemka TECHNOLOGIES
This document discusses two solutions from emka TECHNOLOGIES for noninvasive blood pressure measurement: emkaPACK and nibpSNAPSHOT. EmkaPACK allows for long-term blood pressure measurements on unrestrained animals as an optional feature of their telemetry system, while nibpSNAPSHOT is a handheld device for single-point measurements. Both solutions use the oscillometric technique and are supplied with software for data acquisition and analysis of blood pressure parameters.
Telmisartan is an angiotensin receptor blocker (ARB) that is described as the "master sartan" due to several unique properties. It has a high trough-to-peak ratio, ensuring round-the-clock blood pressure control. It also has protective effects on target organs by reducing early morning blood pressure spikes. Additionally, telmisartan has beneficial effects beyond blood pressure lowering, such as reducing endothelial dysfunction through partial PPAR-gamma activation. These factors make telmisartan effective at preventing cardiovascular events like heart attacks and strokes.
Ambulatory blood pressure monitoring (ABPM) provides a more accurate assessment of a patient's blood pressure over time compared to office readings alone. For patients with chronic kidney disease (CKD), ABPM is especially important as it can identify issues like white coat hypertension, masked hypertension, nocturnal hypertension, and lack of dipping which are risk factors for further kidney function decline and cardiovascular disease. The report from ABPM monitors blood pressure readings taken every 20-30 minutes over 24 hours to establish average blood pressure levels during daytime and nighttime periods and determine if dips in blood pressure at night are occurring.
Hypertension is defined as a systolic blood pressure of 140 mm Hg or higher or a diastolic blood pressure of 90 mm Hg or higher. About 1 billion people worldwide and 1 in 3 Americans have hypertension. Hypertension directly increases the risk of cardiovascular disease. Prehypertension is defined as a systolic blood pressure of 120-139 mm Hg or a diastolic blood pressure of 80-89 mm Hg. The main factors that influence blood pressure are cardiac output, systemic vascular resistance, and fluid volume control by the kidneys. Hypertension can lead to damage of the heart, brain, kidneys, eyes, and vasculature if not properly treated.
This document discusses hypertension, or high blood pressure. It notes that hypertension affects around 50 million people in the US. The main types are primary hypertension, which has no known cause, and secondary hypertension, which is caused by another disease like kidney disease. Risk factors for hypertension include genetics, family history, obesity, stress, alcohol, sodium, tobacco, and age. Untreated hypertension can lead to heart attack, stroke, kidney failure, and vision loss. African Americans have a higher risk than other populations. Treatment involves lifestyle changes and medication, with the goal of controlling blood pressure.
This document discusses guidelines for the management of hypertension. Key points include:
- Longer-acting thiazide-like diuretics are preferred over shorter-acting thiazides.
- Single pill combinations should be used as first-line treatment for hypertension regardless of blood pressure level.
- Blood pressure targets are lower for those at high risk, such as a target under 120 mmHg systolic for those over age 50 with cardiovascular disease.
The document outlines guidelines for the management of arterial hypertension from the 2018 ESC/ESH conference. It discusses definitions of hypertension, recommendations for blood pressure measurement, classifications of hypertension, screening and diagnosis, assessment of hypertension-mediated organ damage, and initiation of blood pressure-lowering treatment. Key points include defining hypertension as a blood pressure over 140/90 mmHg, outlining options for office and out-of-office blood pressure measurement, stratifying cardiovascular risk, and recommending prompt initiation of treatment for grade 2 or 3 hypertension or grade 1 hypertension with high risk or organ damage.
This document discusses health screening services provided by pharmacists, including monitoring chronic conditions like hypertension, diabetes, and asthma. It describes standards for health screening and outlines procedures for measuring blood pressure, blood glucose levels, body mass index, and peak expiratory flow rate. Key aspects of each procedure are explained, such as appropriate measurement techniques and interpretation of results. The overall purpose is to describe health screening services that pharmacists can provide to support early disease detection and chronic disease management.
This presentation focus on the accurate method of BP measurement as well as the presentation of the latest clinical trials of hypertension management and their impact on recent guidelies
Community pharmacy presentation done by roshinee.pptxrroshinee99
Community pharmacies provide several health screening services including blood pressure monitoring, cholesterol testing, blood glucose testing, body mass index assessment, and bone density screening. These screenings play an important role in promoting preventative healthcare by allowing for early detection of conditions like hypertension, diabetes, and osteoporosis. Pharmacies make these services accessible and convenient, helping to improve public health outcomes.
This document provides guidelines for office and out-of-office blood pressure measurement from the 2021 European Society of Hypertension. It recommends using validated automated devices for accuracy and discusses aspects of measurement including white-coat hypertension, masked hypertension, and blood pressure variability. Office blood pressure remains important but can be misleading, so out-of-office methods like ambulatory blood pressure monitoring or home monitoring are recommended when possible to confirm diagnoses and treatment decisions. Standardized measurement techniques aim to improve precision and properly diagnose and manage hypertension.
This document discusses ambulatory blood pressure monitoring (ABPM). It describes how ABPM is used to diagnose conditions like white coat hypertension and nocturnal hypertension. ABPM provides important information about blood pressure over 24 hours that can help guide treatment, especially in elderly patients and those with treatment-resistant hypertension. The document outlines how to perform ABPM, interpret the results, and use ABPM to monitor patients and adjust antihypertensive treatment.
Monitoring is essential in any kind of medical practice. It is the observation of disease, condition and several other parameters over time. Usually a medical monitor is used for continuously measuring vital signs.
This document discusses ambulatory blood pressure monitoring (ABPM) and its role in clinical practice. It provides details on how ABPM works, the various indices that can be analyzed from ABPM reports, and its advantages over office blood pressure readings. ABPM provides a more accurate assessment of a patient's true blood pressure over 24 hours and can detect conditions like white coat hypertension. It is useful for diagnosing hypertension, monitoring treatment effectiveness, and predicting cardiovascular outcomes.
This document provides guidance for dental clinics on preparing for and handling medical emergencies. It stresses the importance of being prepared in advance through staff training, developing an emergency plan, and maintaining an emergency kit. It also provides details on assessing patient health by taking medical histories and vital signs like temperature, pulse, blood pressure, and respiration. Staff should be assigned roles in emergencies and practice emergency response through mock scenarios. Identifying and reducing patient anxiety can help prevent some common emergencies.
Hands on, tips and tricks using PeriFlux 6000Perimed
The aim of this document is to describe the workflow for
the toe and ankle pressure procedure using Perimeds PeriFlux 6000, including some
useful tips and tricks.
Hypertensive urgency and emergency are defined based on whether there is acute end organ damage present. Hypertensive urgency involves severe hypertension without acute end organ damage, while hypertensive emergency involves severe hypertension with acute end organ damage. Accurate blood pressure measurement requires proper technique and positioning. Common forms of acute end organ damage include neurological issues like hypertensive encephalopathy, cardiovascular issues like pulmonary edema, and renal issues like acute kidney injury. Management of hypertensive urgency involves slowly lowering blood pressure over hours to days in a controlled manner to avoid complications, while hypertensive emergency requires immediate treatment to prevent further end organ damage.
Traumatic brain injury compatible versionBharath T
This document discusses traumatic brain injury (TBI). It provides an overview of TBI including the problem statement, pathophysiology, pre-hospital management, monitoring in TBI patients, critical care management, current guidelines and evidence, and prognostication. Key points include that TBI is a leading cause of death and disability, secondary injury can worsen outcomes, and pre-hospital management focuses on oxygenation, ventilation, fluid resuscitation, and transport to a trauma center for further monitoring and treatment.
This document summarizes a seminar on invasive and non-invasive hemodynamic monitoring in the intensive care unit (ICU). It discusses various monitoring techniques including clinical parameters, blood pressure, echocardiography, esophageal Doppler monitoring, gastric tonometry, central venous pressure, and pulmonary artery catheters. For each method, it covers principles of measurement, indications, limitations, evidence, and clinical applications in critically ill patients. The document emphasizes that hemodynamic monitoring should improve outcomes when coupled with effective treatments, and intensive care physicians should be trained in goal-directed echocardiography.
This document discusses health screening services provided by community pharmacies, focusing on blood pressure and blood glucose screening. It defines both screening tests and explains their importance in assessing cardiovascular/diabetes risk and promoting early detection. The document outlines the various methods used (automated monitors, manual, ambulatory monitoring) and provides steps for accurate blood pressure measurement. It emphasizes the role of pharmacists in conducting accessible screenings and improving public health outcomes.
This document discusses multiparameter patient monitors. It begins by introducing monitoring as the observation of various medical parameters over time, usually using a medical monitor. It then lists some of the most common parameters measured by patient monitors, including ECG, blood pressure, heart rate, temperature, and oxygen saturation. The document goes on to describe different types of monitoring like cardiac, hemodynamic, respiratory, neurological, blood glucose, and temperature monitoring. It emphasizes that multiparameter monitors can simultaneously measure and display multiple vital signs, allowing medical staff to continuously monitor a patient's condition and be alerted to any changes.
- Hypertension is defined as systolic blood pressure over 140 mmHg or diastolic over 90 mmHg. Options for blood pressure measurement include office, ambulatory, and home monitoring.
- Ambulatory blood pressure monitoring provides advantages like identifying white-coat hypertension but is more expensive. Home blood pressure monitoring is cheaper but lacks nocturnal readings.
- Uncontrolled hypertension despite three or more antihypertensive classes at maximum dose is defined as resistant hypertension. Causes include non-adherence, secondary causes, and volume overload.
An outbreak of chikungunya virus has spread like an epidemic in the capital city this year, with doctors seeing many young patients suffering from acute joint pain wheelchair bound. While only a few labs can test for the virus, it is estimated that 80% of patients presenting with viral fever and joint pain symptoms at some hospitals have tested positive for chikungunya. The outbreak has been attributed to increased mosquito breeding due to heavy monsoon rains. Treatment involves painkillers, though paracetamol often provides little relief from the debilitating joint pain associated with the illness.
Your plastic water bottle could be as dirty as your toiletNursing Hi Nursing
Researchers tested four types of reusable water bottles and found that bottles that were used for a week without washing had more bacteria than a toilet seat. Specifically, the slide-top bottle had more bacteria than an average toilet seat, pet bowl, or kitchen sink. Over 60% of the bacteria found on the bottles could make people sick. The cleanest bottle type tested was the straw-top bottle, and researchers also found that stainless steel bottles were healthier options than plastic bottles.
This document provides information and strategies for sun safety at resorts. It discusses establishing a sun safety program called "Go Sun Smart" that would provide education materials to guests and training to employees. The program is based on over a decade of sun safety research focusing on outdoor workers and recreationists. The document then covers the skin cancer problem, the effects of UV radiation, assessing personal risk factors, and practicing sun safety strategies like using shade, covering up with protective clothing and sunglasses, and applying sunscreen. It emphasizes the importance of monitoring UV levels and reapplying sunscreen regularly.
The document discusses various topics related to transport operations and ambulance services including emergency vehicle design, checking ambulances, ambulance equipment, driving techniques, incident response, transporting patients, and air medical transports. It provides information on setting up landing zones and transferring patients safely. National EMS education standard competencies are also listed that cover operations, transport safety, medicine, infectious diseases and more.
This document provides information and strategies for sun safety at resorts. It discusses establishing a sun safety program called "Go Sun Smart" that would provide education materials to guests and training to employees. The program is based on over a decade of sun safety research focusing on outdoor workers and recreationists. The document then covers topics like the skin cancer problem, how UV radiation affects skin, assessing personal risk factors, and practicing sun safety strategies like using shade, covering up with protective clothing, and applying sunscreen properly. It emphasizes the importance of early skin cancer detection.
Pizza shops and steakhouses that use charcoal or wood burners produce significant emissions and damage the environment in major cities like Sao Paulo, Brazil. A study found emissions from thousands of pizza shops and domestic waste burning contribute to Sao Paulo's air pollution problems despite its green vehicle policies. While vehicles use cleaner biofuels, emissions from over 800 pizza shops using wood burning stoves daily and over 1,000 pizzas produced for home delivery weekly on wood burning stoves negate some of the environmental benefits.
The document discusses the effects of marijuana use and abuse. It defines marijuana and how it is consumed. It outlines short-term effects like rapid heart rate and long-term effects on the brain, lungs and other organs. Signs of addiction and dependency are provided. Treatment typically involves detoxification and support to reintegrate into society. Myths about marijuana are debunked, such as it being safe because it is a plant. The summary emphasizes that marijuana is harmful and can isolate users from society, and that treatment requires holistic social support.
Bill Gates says that genetically modified mosquitoes may be used to fight malaria within the next five years. Researchers are using a gene editing technique called a "gene drive" to alter mosquitoes so they are resistant to diseases like malaria and dengue. Gates believes this technology could dramatically reduce malaria deaths by suppressing mosquito populations. However, some scientists have raised concerns that unintended mutations in released mosquitoes could have unknown consequences.
A study from the University of Manchester found that frequent childhood moves, especially during early adolescence, are linked to higher risks of negative outcomes in adulthood such as suicide attempts, criminal violence, mental illness, substance abuse, and premature death. The researchers collected data on all people born in Denmark from 1971 to 1997, documenting every residential move from birth to age 14, and correlated subsequent adverse events in adulthood.
An international team of scientists reviewed 19 previous studies involving 68,000 elderly people and found no link between high cholesterol levels and heart disease in those over 60 years old. The study suggests that 92% of elderly people with high cholesterol lived as long or longer than those with low cholesterol. The authors call for a reevaluation of statin prescriptions for the elderly, but their findings have been criticized by other academics who question the research methods. Some experts say that as people age, many other factors impact health, making the effects of high cholesterol less clear.
India has seen a decline in childhood stunting but now faces rising issues with diabetes and being overweight. The number of diabetics in India is projected to increase to over 100 million in the next 15 years. While India has made progress against undernutrition, public health policies now need to also address the growing problems of overnutrition and diabetes. Non-communicable diseases like heart disease also place a large economic burden on Indian families.
Scientists have developed the world's first vaccine for Toxic Shock Syndrome (TSS), a severe circulatory and organ failure caused by bacterial toxins from Staphylococcus bacteria. The vaccine was successfully tested in a Phase I trial. TSS, also known as "tampon disease", often affects young women using super absorbent tampons and was first described in the 1980s. This led to regulations on the absorbency of tampons.
Saxbee Consultants holds the number 1 position across major social media platforms when searched, including Google, Yahoo, Bing, Facebook, LinkedIn, SlideShare, Twitter, and India Mart. The document lists Saxbee Consultants as having the top result on each of these search and social media sites.
According to research studies, employee health risks are directly related to increased costs for companies, as healthy employees can contribute up to 12.5% more to a company. The document also lists various health and wellness magazines and journals the trainer has experience with, and states that the goal is to help individuals tap their highest potential through healthier lifestyle choices involving exercise and mental stimulation.
Nurses and attendants are available to provide care for a healthy recovery. This email is regarding nurse staffing and bookings can be made by contacting nursingnursing@yahoo.in. Happy Nurse Day.
Saxbee Consultants is collecting ideas from the public to present to the Prime Minister of India on January 31, 2016. The public is encouraged to submit their ideas for building a stronger India by emailing them to saxbeeconsultantspm@gmail.com. Saxbee Consultants previously faced a technical issue that prevented emails from being received but their technicians have now fixed the problem, so the public is asked to resend any ideas they had submitted.
Saxbee Consultants is collecting ideas from the public to present to the Prime Minister of India on January 31, 2016. The public is encouraged to submit their ideas for building a stronger India by emailing them to saxbeeconsultantspm@gmail.com. Saxbee Consultants previously faced a technical issue that prevented emails from being received but their technicians have now fixed the problem, so the public is requested to resend any ideas.
Saxbee Consultants is collecting ideas from the public to present to the Prime Minister of India on January 31, 2016. The public is encouraged to submit their ideas for building a stronger India by emailing them to saxbeeconsultantspm@gmail.com. Saxbee Consultants previously faced a technical issue that prevented emails from being received but their technicians have now fixed the problem, so the public is asked to resend any ideas they had submitted.
Air India has introduced yoga sessions for newly-recruited cabin crew and pilots undergoing training, as well as a two-day yoga workshop for senior management, to help staff cope with stress and bring discipline. Trainees are required to attend early morning yoga sessions, while the workshop for managers will be held later in June. The initiatives were proposed by Air India's personnel department and coincide with Prime Minister Modi's push to celebrate International Yoga Day.
The author discusses the health risks of raising children in Delhi, India due to the city's extremely high air pollution levels. He describes how his young son was hospitalized twice for respiratory issues caused by Delhi's air. Experts advise that the pollution will likely cause permanent lung damage in children and reduce their life expectancy. While some expats choose to remain in Delhi for work, the author is reconsidering staying due to the threats to his family's health from the polluted air and contaminated water.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Kosmoderma Academy, a leading institution in the field of dermatology and aesthetics, offers comprehensive courses in cosmetology and trichology. Our specialized courses on PRP (Hair), DR+Growth Factor, GFC, and Qr678 are designed to equip practitioners with advanced skills and knowledge to excel in hair restoration and growth treatments.
8. BP Treatment
Targets
Condition
160/100 Treatment threshold if no risk
factors,TOD or CCD
< 140/90 Treatment target for office BP
measurement
< 135/85 Treatment target for ABP or HBP
measurement
< 130/80 Treatment target for for Type 2
diabetics or non-diabetic
nephropathy
< 125/75 Treatment target for diabetic or
non-diabetic nephropathy with
proteinuria
Slide 5
Studies show that a multitude of diseases are attributable to hypertension.
They include:
• Heart failure
• Coronary heart disease
• Myocardial infarction
• Left ventricular hypertrophy and failure
• Aortic aneurysm
• Peripheral vascular disease
• Retinopathy
• Hypertensive encephalopathy
• Chronic kidney failure
• Cerebral hemorrhage
• Stroke
With so many diseases linked to hypertension, prompt and effective treatments have the potential to reduce many complications.
Dustan HP, et al. Arch Intern Med 1996; 156:1926-1935.
Slide 6
Despite the advances that have been made in the treatment of hypertension over the last 50 years, it is clear that there is still room for improvement in the management of this condition. Less than 40% of of Canadians with hypertension are treated for their condition. Only 16% those receiving treatment have their blood pressure controlled (BP &lt; 140/90).
Joffres MR, et al. Awareness, Treatment, and Control of Hypertension in Canada. Am J Hypertens 1997; 10:1097-1102.
An aneroid sphygmomanometer found in my partner’s medical bag – the needle was noted to be “off – zero”
Subsequently, others have studied the BpTRU in both research and clinical settings.
This study was presented by Dr. Martin Myers of the U. of Toronto at the CHS meeting last October, and will be published in the American Journal of Hypertension next month. In comparing the BpTRU to a specialist BP, FP BP, research technician and ABP it shows the BpTRU to be as accurate as a research technician.
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Slide 22
Hypertension increases the risk of target organ damage (i.e. cerebrovascular, cardiovascular and renal events).
Several studies have reported a closer relationship between target organ damage and blood pressure when blood pressure was recorded by 24-h ambulatory blood pressure monitoring (ABPM) compared with conventional measurements of blood pressure at the clinic (Mancia 1990; Devereux, et al 1987).
A consistent pattern is seen whether target organ damage is assessed by an overall score, left ventricular mass index (LVMI), left ventricular wall thickness, or retinopathy (Sokolow, et al 1966; Devereux, et al 1983; Parati, et al 1987).
Sokolow M, Werdegar D, Kain HK, Hinman AT. Relationship between level of blood pressure measured causally and by portable recorders and severity of complications in essential hypertension. Circulation 1966; 34:279-298.
Devereux RB, Pickering TG, Harshfield GA et al. Left ventricular hypertrophy in patients with hypertension: importance of blood pressure response to regularly recurring stress. Circulation 1983; 68:470-476.
Devereux RB, Pickering TG, Alderman MH, Chiken S, Borer JS, Laragh JH. Left ventricular hypertrophy in hypertension: prevalence and relationship to pathophysiologic variables. Hypertension 1987; 9: (Suppl II):1153-1160.
Parati G, Pomidossi G, Albini F, Malaspina D, Mancia G. Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. J Hypertens 1987; 5:93-98.
Mancia G. Ambulatory blood pressure monitoring: research and clinical applications. J Hypertens 1990; 8 (Suppl 7): S1-S13.
Slide 24
Most patients with essential hypertension are ‘dippers’ - patients experience the same circadian pattern as normotensives with a night-time dip in blood pressure (Mancia, et al 1983).
The ‘normal’ circadian pattern is lost in some patients with essential hypertension (‘non-dippers’). There appears to be a greater prevalence of this phenomenon in patients with secondary hypertension, renal insufficiency, pre-eclampsia, in elderly hypertensives, and in the accelerated form of malignant hypertension (Redman, et al 1976; Kobrin, et al 1984; Baumgart, et al 1989; Imai, et al 1990; Portaluppi, et al 1991).
Redman CWG, Beilin LJ, Bonnar J. Reversed diurnal blood pressure rhythm in hypertensive pregnancies. Clin Sci Mol Med 1976; 51:687-688.
Mancia G, Ferrari A, Gregorini L et al. Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res 1983; 53:96-104.
Kobrin I, Oigman W, Kumar A et al. Diurnal variation of blood pressure in elderly patients with essential hypertension. J Am Geriatr Soc 1984; 32:869-879.
Baumgart P, Walger P, Gerke M, Dorst K-G, Vetter H, Raum K-H. Nocturnal hypertension in renal failure hemodialysis and after renal transplantation. J Hypertens 1989; 7 (Suppl 6):70-71.
Imai Y, Abe K, Munakata M et al. Does ambulatory blood pressure monitoring improve the diagnosis of secondary hypertension? J Hypertens 1990; 8 (Suppl 6):71-78.
Portaluppi F, Montanari L, Massari M, Di Chiari V, Capanna M. Loss of nocturnal decline of blood pressure in hypertensives due to chronic renal failure. Am J Hypertens 1991; 4:20-26.
Slide 27
Blood pressure falls during sleep and rises rapidly just before the time of awakening and arising (Millar-Craig, et al 1978; Mancia, et al 1983).
Millar-Craig M, Bishop CN, Raftery EB. Circadian variation of blood pressure. Lancet 1978; I: 795-797.
Mancia G, Ferrari A, Gregorini L, et al. Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res 1983; 53:96-104.
Slide 29
Epidemiological evidence shows that CHD morbidity and mortality are greatest in the morning waking period (Muller, et al 1985; Thompson, et al 1985; Muller, et al 1987; Rocco, et al 1987; Willich, et al 1987; Mulcahy, et al 1988), between 8 am and 12 noon (Rocco, et al 1987).
The peak incidence of cardiovascular events is associated with the BP surge that occurs as people arise and begin their routine daytime activities (Rocco, et al 1987).
Muller JE, Stone PH, Turi ZG, et al. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med 1985; 313:1315-1322.
Thompson DR, Blandford RL, Sutton TW, Marchant PR. Time of onset of chest pain in acute myocardial infarction. Int J Cardiol 1985; 7:139-146.
Muller JE, Ludmer PL, Willich SN, et al. Circadian variation in the frequency of sudden cardiac death. Circulation 1987; 75:131-138.
Rocco MB, Barry J, Campbell S, et al. Circadian variation of transient myocardial ischaemia in patients with coronary artery disease. Circulation 1987; 75:395-400.
Willich SN, Levy D, Rocco MB, Tofler GH, Stone PH, Muller JE. Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population. Am J Cardiol 1987; 60:801-806.
Mulcahy D, Keegan J, Cunningham D et al. Circadian variation of total ischaemic burden and its alteration with anti-anginal agents. Lancet 1988; ii:755-759.
Willich SN, Goldberg RJ, Maclure M, Perriello L, Muller JE. Increased onset of sudden cardiac death in the first three hours after awakening. Am J Cardiol 1992; 70:65-68.