This document presents an overview of the Blockchain applications in Life Sciences. The applications are mapped onto Life Sciences value chain – preclinical, clinical, manufacturing, distribution, and customer. Blockchain could be used in many applications across the value chain including but not limited to peer-to-peer network, data storage, smart contracts and file sharing. This innovative technology presents a lot of promise in accelerating drug discovery and removing many inefficiencies.
This disclaimer informs readers know that the views, thoughts, and opinions expressed in the presentation belong solely to the author, and not to the author’s employer, organization, committee or other group or individual.
A.Schumacher (2017) Blockchain & Healthcare: A Strategy GuideGalen Growth
The healthcare industry needs a revolution – and it is here now. Trusted and open R&D processes, auditable & secure transactions between parties, authenticated by mass collaboration and powered by collective self-interest, rather than by fewer and fewer pharmaceutical giants motivated by profit alone. This healthcare ecosystem is immune to exorbitant drug prices, tampering, fraud, or political control. The name of the technology that makes all this happen is blockchain, a tool that will fundamentally change the healthcare sector. Blockchain will prove to be indispensable in building a global precision-medicine ecosystem that optimally connects patients, clinicians, researchers, insurers and clinical laboratories to one another.
Implementing Blockchain applications in healthcarePistoia Alliance
Blockchain technology can revolutionise the way information is exchanged between parties by bringing an unprecedented level of security and trust to these transactions. The technology is finding its way into multiple use cases but we are yet to see full adoption and real-world business implementation in the Healthcare industry.
In this webinar we will explore the main challenges and considerations for the implementation of Blockchain technology in Healthcare use cases. This is the third webinar in our Blockchain Education series.
This provides a deep intro to the blockchain technology, and explores several use-cases within healthcare where it could lead to disruption and add value
Healthcare Blockchain Summit, Washington DC Mar 21, 2017Edward Bukstel
There is much talk of how Blockchain will revolutionize healthcare. This hype must be tempered by the fact that healthcare already has a trust factor built-in, or patients would not take pills prescribed by doctors, or let providers stick needles in their bodies. It is often said that “Riches are in Niches,” and this is the case for blockchain and areas that are tangential to the direct care of the patient.As referenced in the 2015 ONC Interoperability Roadmap, Social Determinants of Health (SDoH) will need to be connected to the patients’ health status. Physicians currently monitor carboxyhemoglobin as an indicator of a patient’s level of smoking. As part of a smoking cessation program, a smart contract on the clinical Blockchain could identify normal blood carboxyhemoglobin (COhb) as reported by a clinical reference lab from the Laboratory Analyzer Blockchain and execute a request to increase an incentive benefit controlled by a “private / permissioned” USDA Clinical Blockchain. The clinical Blockchain will track the specific “chain of custody” from iStat Analyzer (Accriva, Radiometer, etc…) to the patient test results report, which triggers the smart contract with the USDA to distribute an incentive. Both the physician and the patient are notified of the disbursement. Similar use cases could be implemented for patients with diabetes, and obesity, helping people live healthy lives.
A.Schumacher (2017) Blockchain & Healthcare: A Strategy GuideGalen Growth
The healthcare industry needs a revolution – and it is here now. Trusted and open R&D processes, auditable & secure transactions between parties, authenticated by mass collaboration and powered by collective self-interest, rather than by fewer and fewer pharmaceutical giants motivated by profit alone. This healthcare ecosystem is immune to exorbitant drug prices, tampering, fraud, or political control. The name of the technology that makes all this happen is blockchain, a tool that will fundamentally change the healthcare sector. Blockchain will prove to be indispensable in building a global precision-medicine ecosystem that optimally connects patients, clinicians, researchers, insurers and clinical laboratories to one another.
Implementing Blockchain applications in healthcarePistoia Alliance
Blockchain technology can revolutionise the way information is exchanged between parties by bringing an unprecedented level of security and trust to these transactions. The technology is finding its way into multiple use cases but we are yet to see full adoption and real-world business implementation in the Healthcare industry.
In this webinar we will explore the main challenges and considerations for the implementation of Blockchain technology in Healthcare use cases. This is the third webinar in our Blockchain Education series.
This provides a deep intro to the blockchain technology, and explores several use-cases within healthcare where it could lead to disruption and add value
Healthcare Blockchain Summit, Washington DC Mar 21, 2017Edward Bukstel
There is much talk of how Blockchain will revolutionize healthcare. This hype must be tempered by the fact that healthcare already has a trust factor built-in, or patients would not take pills prescribed by doctors, or let providers stick needles in their bodies. It is often said that “Riches are in Niches,” and this is the case for blockchain and areas that are tangential to the direct care of the patient.As referenced in the 2015 ONC Interoperability Roadmap, Social Determinants of Health (SDoH) will need to be connected to the patients’ health status. Physicians currently monitor carboxyhemoglobin as an indicator of a patient’s level of smoking. As part of a smoking cessation program, a smart contract on the clinical Blockchain could identify normal blood carboxyhemoglobin (COhb) as reported by a clinical reference lab from the Laboratory Analyzer Blockchain and execute a request to increase an incentive benefit controlled by a “private / permissioned” USDA Clinical Blockchain. The clinical Blockchain will track the specific “chain of custody” from iStat Analyzer (Accriva, Radiometer, etc…) to the patient test results report, which triggers the smart contract with the USDA to distribute an incentive. Both the physician and the patient are notified of the disbursement. Similar use cases could be implemented for patients with diabetes, and obesity, helping people live healthy lives.
Blockchain Health and Crypto Wellness FuturesMelanie Swan
The blockchain is a new class of information technology that could be like the Internet in terms of pervasively reconfiguring all of human activity, at minimum facilitating decentralized models as a technologically-resilient and liberty-enhancing complement to centralized hierarchical models. There are many potential applications in health and life sciences
Top 10 companies using blockchain for healthcare securityBlockchain Council
A block in a blockchain refers to a collection of data. A blockchain is immutable as it is impossible to change data once it is added to the blockchain. The blocks are linked to form a chain and this is what makes a blockchain so trustworthy. It is this decentralized nature of blockchain, which makes doctors, patients, and healthcare providers to gain access to the same information quickly and safely.
Blockchain is a disruptive technology currently becoming the news topic of everyday. This presentation explains three essential questions relating to Blockchain:
1) Why to use it?
2) How does Blockchain actually work?
3) Where its currently being used and where it could be used.
Few examples have been explained using the Blockchain 1.0 i.e. BitCoin Blockchain.
Some use cases have been visited in this ppt.
Microsoft Azure for Blockchain as a Service (BaaS) has also been touched upon.
Blockchain, Predictive Analytics and HealthcareRuchi Dass
Episode-of-care payment and comprehensive care payment systems can help providers prevent health problems; prevent the occurrence of acute episodes among individuals who have health conditions; prevent poor outcomes during major acute episodes, such as infections, complications, and hospital readmissions; and reduce the costs of successful treatment.
Using cryptography to keep exchanges secure, blockchain provides a decentralized database, or “digital ledger”, of transactions that everyone on the network can see. This network is essentially a chain of computers that must all approve an exchange before it can be verified and recorded.
Learn more about Blockchain in healthcare here.
Blockchain has become a popular technical term to drop over the past six months, most people cannot effectively explain Blockchain or describe its real value and application to the marketplace. Hopefully, this presentation will help you better understand...
Presentation on the subject of personal health data, blockchain technology and my master's thesis project.
"Donate Your Data" provides individuals with the option to take ownership of their personal health data and make choices on how it is donated for use within health research studies.
It is a first step towards a future in which data-driven services are designed according to citizen data rights, offering both data security and transparency over its use to each and every person.
(First presented to BCGDV in Berlin on September 1, 2017.)
I created this presentation for a client who wanted to understand how blockchain technology can be used in healthcare, particularly for eHR (electronic health record). They wanted a non-technical overview.
My presentation on #Blockchain technology and the opportunity to improve #Healthcare. I presented it at #HIMSSEurope during the #eHealthWeek in Malta on May 2017.
Blockchain for Executives, Entrepreneurs and InvestorsFenbushi Capital
A brief summary of key issues that executives, entrepreneurs and investors across all industries should be aware of when considering blockchain.
First presented 8 June 2018 at the Longhash Incubator in Singapore.
The Quest for Enterprise Blockchain Solutions.Fran Strajnar
This presentation was delivered to the sold-out Ethereum.nz events on the 17th & 19th May 2016.
Blockchain for Enterprise:
•Exponential Tech & Macro
•5 Pillars / 3 Layers
•Solution Designs Examples
•Standards & Protocols
•Conclusion
Starting off by identifying the behavior of 'Exponential' technology and digging into the Macro-view of Blockchain's evolving out of it's early 'infrastructure building' days.
We take a look at the '5 Pillars & 3 Layers to Enterprise Blockchain Solution Design', breaking down what goes where and how to start.
Followed by examples of solutions design in Banking, Cross-Border Payments & Supply Chain.
Concluding with a comparison to the early internet days, where protocols and standards are continually evolving and what this means for Blockchain design considerations today.
If Blockchain Technology Interest you - please see BraveNewCoin.com for News, Analysis, charts, research and much more resources.
A primer on Blockchain, Semantic Web and Ricardian Contracts.
Semantic Blockchain is a proposal where the Semantic Web meets the Blockchain. Combining these two technologies could provide the Semantic web with a transparent proof of work and trust mechanism while conversely disambiguating data stored on the blockchain, solving one of the key challenges with Riccardian/Smart contracts. This presentation will explore how these two technologies might be combine using the example of a smart contract. However the potential application is much bigger and could provide a key back bone underlying the Internet of Things.
In this case study, we are providing information about the Introduction of Blockchain Technology, Bitcoin and its environment setup, Ethereum coin, other cryptocurrencies, Bitcoin in education, and a case study of healthcare using blockchain.
Digital platforms could disrupts how pharma companies plan and excecute clini...Jayanthi Repalli, PhD
Pharmaceutical companies spent millions of dollars every year on clinical trials. They are essential part of finding new drugs. However, the lack of participants is the major cause for the delay of trials. Digital platforms could solve this problem for pharm companies and accelerate new drug development. Hope you find this infographic useful. Feel free to drop a note!
This disclaimer informs readers know that the views, thoughts, and opinions expressed in the presentation belong solely to the author, and not to the author’s employer, organization, committee or other group or individual.
Blockchain Health and Crypto Wellness FuturesMelanie Swan
The blockchain is a new class of information technology that could be like the Internet in terms of pervasively reconfiguring all of human activity, at minimum facilitating decentralized models as a technologically-resilient and liberty-enhancing complement to centralized hierarchical models. There are many potential applications in health and life sciences
Top 10 companies using blockchain for healthcare securityBlockchain Council
A block in a blockchain refers to a collection of data. A blockchain is immutable as it is impossible to change data once it is added to the blockchain. The blocks are linked to form a chain and this is what makes a blockchain so trustworthy. It is this decentralized nature of blockchain, which makes doctors, patients, and healthcare providers to gain access to the same information quickly and safely.
Blockchain is a disruptive technology currently becoming the news topic of everyday. This presentation explains three essential questions relating to Blockchain:
1) Why to use it?
2) How does Blockchain actually work?
3) Where its currently being used and where it could be used.
Few examples have been explained using the Blockchain 1.0 i.e. BitCoin Blockchain.
Some use cases have been visited in this ppt.
Microsoft Azure for Blockchain as a Service (BaaS) has also been touched upon.
Blockchain, Predictive Analytics and HealthcareRuchi Dass
Episode-of-care payment and comprehensive care payment systems can help providers prevent health problems; prevent the occurrence of acute episodes among individuals who have health conditions; prevent poor outcomes during major acute episodes, such as infections, complications, and hospital readmissions; and reduce the costs of successful treatment.
Using cryptography to keep exchanges secure, blockchain provides a decentralized database, or “digital ledger”, of transactions that everyone on the network can see. This network is essentially a chain of computers that must all approve an exchange before it can be verified and recorded.
Learn more about Blockchain in healthcare here.
Blockchain has become a popular technical term to drop over the past six months, most people cannot effectively explain Blockchain or describe its real value and application to the marketplace. Hopefully, this presentation will help you better understand...
Presentation on the subject of personal health data, blockchain technology and my master's thesis project.
"Donate Your Data" provides individuals with the option to take ownership of their personal health data and make choices on how it is donated for use within health research studies.
It is a first step towards a future in which data-driven services are designed according to citizen data rights, offering both data security and transparency over its use to each and every person.
(First presented to BCGDV in Berlin on September 1, 2017.)
I created this presentation for a client who wanted to understand how blockchain technology can be used in healthcare, particularly for eHR (electronic health record). They wanted a non-technical overview.
My presentation on #Blockchain technology and the opportunity to improve #Healthcare. I presented it at #HIMSSEurope during the #eHealthWeek in Malta on May 2017.
Blockchain for Executives, Entrepreneurs and InvestorsFenbushi Capital
A brief summary of key issues that executives, entrepreneurs and investors across all industries should be aware of when considering blockchain.
First presented 8 June 2018 at the Longhash Incubator in Singapore.
The Quest for Enterprise Blockchain Solutions.Fran Strajnar
This presentation was delivered to the sold-out Ethereum.nz events on the 17th & 19th May 2016.
Blockchain for Enterprise:
•Exponential Tech & Macro
•5 Pillars / 3 Layers
•Solution Designs Examples
•Standards & Protocols
•Conclusion
Starting off by identifying the behavior of 'Exponential' technology and digging into the Macro-view of Blockchain's evolving out of it's early 'infrastructure building' days.
We take a look at the '5 Pillars & 3 Layers to Enterprise Blockchain Solution Design', breaking down what goes where and how to start.
Followed by examples of solutions design in Banking, Cross-Border Payments & Supply Chain.
Concluding with a comparison to the early internet days, where protocols and standards are continually evolving and what this means for Blockchain design considerations today.
If Blockchain Technology Interest you - please see BraveNewCoin.com for News, Analysis, charts, research and much more resources.
A primer on Blockchain, Semantic Web and Ricardian Contracts.
Semantic Blockchain is a proposal where the Semantic Web meets the Blockchain. Combining these two technologies could provide the Semantic web with a transparent proof of work and trust mechanism while conversely disambiguating data stored on the blockchain, solving one of the key challenges with Riccardian/Smart contracts. This presentation will explore how these two technologies might be combine using the example of a smart contract. However the potential application is much bigger and could provide a key back bone underlying the Internet of Things.
In this case study, we are providing information about the Introduction of Blockchain Technology, Bitcoin and its environment setup, Ethereum coin, other cryptocurrencies, Bitcoin in education, and a case study of healthcare using blockchain.
Digital platforms could disrupts how pharma companies plan and excecute clini...Jayanthi Repalli, PhD
Pharmaceutical companies spent millions of dollars every year on clinical trials. They are essential part of finding new drugs. However, the lack of participants is the major cause for the delay of trials. Digital platforms could solve this problem for pharm companies and accelerate new drug development. Hope you find this infographic useful. Feel free to drop a note!
This disclaimer informs readers know that the views, thoughts, and opinions expressed in the presentation belong solely to the author, and not to the author’s employer, organization, committee or other group or individual.
Blockchain Thinking: The Brain as a DAC (Decentralized Autonomous Corporation)Melanie Swan
This talk explores how thinking could be formulated as a blockchain process that could have benefits for both artificial intelligence and human enhancement. Some possibilities might include the ability to orchestrate digital mindfile uploads, advocate for digital intelligences in future timeframes, implement smart contract-based utility functions, instantiate thinking as a power law, and facilitate the enactment of Friendly AI.
Cryptocitizen: Smart Contracts, Pluralistic Morality, and Blockchain SocietyMelanie Swan
Blockchain technology is not just about registering wills and IP on blockchains, and bank transfers taking less than 3 days to settle, philosophically blockchains invite a new level of thinking about what it is to be a cryptocitizen and possibilities for societal design
Blockchain in Supply Chain Management: Fad or Potential?Xeneta
Security, transparency of movement throughout the supply chain and electronically initiating and enforcing contracts, are vital for successful supply chains. Blockchain technology is is facilitating visibility and efficiency in transaction in various industries. In our latest survey, we asked if blockchain technology will help ease and make admininstration work in SCM more efficient.
Bitcoin and Blockchain Technology Explained: Not just Cryptocurrencies, Econo...Melanie Swan
The blockchain concept may be one of the most transformative ideas to impact the world since the Internet. It represents a new organizing paradigm for all activity and integrates humans and technology. Cryptocurrencies like bitcoin are merely one application of the blockchain concept. The blockchain is a public transaction ledger built in a network structure based on cryptographic principles so there does not need to be a centralized intermediary. Any kind of asset (art, car, home, financial contract) may be encoded into the blockchain and transacted, validated, or preserved in a much more efficient manner than at present including ideas, health data, financial assets, automobiles, and government documents. Blockchain technology applies well beyond cryptocurrencies, economics, and markets to all venues of human information processing, collaboration, and interaction including art, health, and literacy.
There are new and emerging opportunities for organisations in all sectors to create and deliver compelling services for their customers using the power of disruptive innovation. As organisations formulate their plans for the coming months, this paper aims to help business and public sector leaders understand the cultural and organisational challenges that are inevitably brought by the use of blockchain technologies, and provides them with the insights they need to overcome them.
Blockchain: The Information Technology of the FutureMelanie Swan
The blockchain concept may be one of the most transformative ideas to impact the world since the Internet. Cryptocurrencies like bitcoin are merely one application of the blockchain concept. The blockchain is a public transaction ledger built in a decentralized network structure based on cryptographic principles so that any kind of trading, buying and selling of assets does not need to go through a centralized intermediary. Any kind of asset may be encoded into the blockchain and transacted, validated, or preserved in a much more efficient manner than at present including ideas, health data, financial assets, automobiles, and government documents. Venture Capitalists are calling the blockchain the next big investment wave.
Stigmergic Economy And Large-Scale, Decentralized Networks - Matan FieldNetwork Society Research
What would it look like if billions of people would be spontaneously, freely and systematically cooperating with each other, on anything? Imagine a self-organized world, with Facebook network but no Facebook Inc., a decentralised transportation network without Lyft or Uber, peer-to-peer marketplaces replacing eBay or Amazon, millions of people insuring each others and building startups together.
This vision is beginning to unfold, with the advent of the blockchain — a decentralized computer —rapidly developing over the last couple of years. Backfeed completes the picture with a set of economic and collaborative protocols, including a p2p review, evaluation and reputation system, distribution of value-carrying tokens and incentive model for the indirect coordination of agents. Imagine a new economic framework, where collaboration is the winning strategy.
In fact, Nature has already came up with an example millions years ago. Ants, birds and fish make up amazingly complex and seemingly intelligent structures in a spontaneous and decentralized way. It is called Stigmergy — a signal-based, indirect coordination of agents. Backfeed’s protocols do the same for human being, but in a generic and systematic manner, fitting any type of cooperation.
In my talk I will present the state-of-the art of decentralized models for cooperation and distributed architecture, the tools and platform, and some preliminary real use cases in the making.
Delivered at the Network Society World Congress in Turin, Italy, on October 15, 2015 - http://netsoc.org/congress
Clinical trial data wants to be free: Lessons from the ImmPort Immunology Dat...Barry Smith
Presentation to the Clinical and Research Ethics Seminar, Clinical and Translational Science Center, Buffalo, January 21, 2014
https://immport.niaid.nih.gov/
http://youtu.be/booqxkpvJMg
ANZCTR: Why we need better sharing of clinical trial dataARDC
Presentation by Ailsa Langford, ANZCTR. Presented at the ANDS/Intersect sharing health-y data: challenges and solutions II workshop on 26th October 2016
January 23, 2017
The Fifth Annual Health Law Year in P/Review symposium featured leading experts discussing major developments during 2016 and what to watch out for in 2017. The discussion at this day-long event covered hot topics in such areas as health policy under the new administration, regulatory issues in clinical research, law at the end-of-life, patient rights and advocacy, pharmaceutical policy, reproductive health, and public health law.
The Fifth Annual Health Law Year in P/Review was sponsored by the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School, Harvard Health Publications at Harvard Medical School, Health Affairs, the Hastings Center, the Program On Regulation, Therapeutics, And Law (PORTAL) in the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital, and the Center for Bioethics at Harvard Medical School, with support from the Oswald DeN. Cammann Fund.
Learn more on our website: http://petrieflom.law.harvard.edu/events/details/5th-annual-health-law-year-in-p-review
Building Highly Scalable Immersive Media Solutions on AWSETCenter
Immersive media content such as 360 degree video places a unique set of demands on cloud-based infrastructure from a complete end to end solution point of view. A key goal for any solution of this nature is to keep costs low while not impacting availability, scale and compute performance. In this talk we will look at how to solve ingest, processing, storage and delivery of live and on-demand content for immersive media delivery, and present a reference design for 360 degree streaming using best-practice architectural patterns.
Speakers: Konstantin Wilms, Principal Solutions Architect M&E, AWS and Chad Schmutzer, Specialist Solutions Architect SPOT, AWS
Case Study "Meeting Meaningful Use Requirements Using HIE"
This presentation will provide an overview of health information exchange in Kansas including a description of how the Kansas Health Information Network (KHIN) is helping Kansas providers meet Stage 1 and Stage 2 Meaningful Use requirements that are necessary to receive Medicare and Medicaid incentive payments. It will include a live demonstration of the health information exchange and a question and answer session.
KHIN provides health information exchange services to all health care providers in Kansas. The KHIN network allows health care providers to share health information at the point of care. Health data includes current diagnosis, medications, allergies, lab results, procedures, immunizations, visit history and summary of care documents.
In August 2012, Via Christi Health Systems and HCA Wesley became the first Kansas health care organizations to share health data. Just 10 months later, 42 Kansas health care systems are live sharing data including all of the largest health systems in Kansas. Nineteen others are actively testing data and 3200 providers have the ability to exchange secure messages. KHIN members can now access information on almost 900,000 Kansas patients, electronically send immunizations to the state registry, electronically send syndromic surveillance data to the CDC and securely communicate with other health care providers through the DIRECT protocols which comply with all HIPAA regulations. Soon, KHIN members will be able to provide a personal health record (PHR) to all of their patients.
Learning Objectives:
∙ Understand the basic principles of health information exchange through a case study of the Kansas Health Information Network (KHIN).
∙ Understand the role of health information exchange in meeting Stage 1 and Stage 2 Meaningful Use requirements.
∙ Describe how health information exchange can facilitate population health and patient engagement.
Blockchain: A Catalyst for the Next Wave of Progress in the Life Sciences Ind...Cognizant
By applying block chain technology, pharmaceuticals companies and medical device makers can eliminate costly intermediaries and more effectively ensure security, immutability, transparency, auditability and trust across the value chain.
By applying shared ledgers, smart contracts and powerful
encryption technology, pharmaceuticals companies and medical
device makers can eliminate costly intermediaries and more
effectively ensure security, immutability, transparency, auditability and trust across the value chain.
An electronic Medical record (EHR) is a of a computerized version of a patient's paper record. Our reality
has been drastically changed by advanced innovation like – PDAs, tablets, and web-empowered gadgets
have changed our day to day lives and the manner in which we impart. Medication is a data rich enterprise.
EHR incorporate the clinical and treatment chronicles of patients, an EHR framework is worked to go past
standard clinical information gathered in a supplier's office and can be a more extensive perspective on a
patient's consideration. Electronic Health Record (EHR) frameworks face issues with respect toinformation
security, honesty and the board. We could execute blockchain innovation to change the EHR frameworks
and could be an answer of these issues. The main goal of our proposed structure is to implement and
execute blockchain innovation for EHR and furthermore to give secure capacity of electronic records by
characterizing granular access rules for the clients of the proposed framework. Thus this structure furnishes
the EHR framework with the advantages of having a versatile, secure and necessary integral chain-based
arrangement
Blockchain is a peer-to-peer distributed ledger technology that helps obtain transparency and trust. Due to these two benefits Blockchain technology is integrated in the healthcare industry. From better pharma supply chains to removal of third parties, this distributed leger technology presents many benefits. Blockchain’s opportunities in patient-data portability, interoperability, and administration can provide answers to various challenges in the Healthcare industry. Swipe through this presentation to know more.
Visit us now at https://www.debutinfotech.com/blockchain-development-services
"Does blockchain hold the key to a new age of supply chain transparency and t...eraser Juan José Calderón
The report, "Does blockchain hold the key to a new age of supply chain transparency and trust?", provides a comprehensive overview into the businesses and geographies that are ramping up their blockchain readiness, and predicts that blockchain will enter mainstream use in supply chains by 2025. Currently, just 3% of organizations that are deploying blockchain do so at scale and 10% have a pilot in place, with 87% of respondents reporting to be in the early stages of experimentation with blockchain.
The UK (22%) and France (17%) currently lead the way with at-scale and pilot implementation1 of blockchain in Europe, while the USA (18%) is a front-runner in terms of funding blockchain initiatives. These "pacesetters"2 are optimistic that blockchain will deliver on its potential, with over 60% believing that blockchain is already transforming the way they collaborate with their partners.
The study also found that cost saving (89%), enhanced traceability (81%) and enhanced transparency (79%) are the top three drivers behind current investments in blockchain. Furthermore, blockchain enables information to be delivered securely, faster and more transparently. The technology can be applied to critical supply chain functions, from tracking production to monitoring food-chains and ensuring regulatory compliance. Enthused by the results they are seeing, the pacesetters identified in the study are set to grow their blockchain investment by 30% in the next three years.
In this webinar Prof. Banafa will discuss in details the use of Blockchain in the following businesses: Insurance; Payments; Internet-of-Things (IoT); Supply Chain; Healthcare; Government; Identity; Advertising; Marketing; Banking.
Evaluating How Blockchain Can Transform the Pharmaceutical and Healthcare Ind...Kate Barlow
- Collaborating with 17 companies across the industry
- Understanding the landscape in the pharma and healthcare settings
- Exploring the areas where Blockchain could be used
- Presenting two detailed use cases (a. Smart Contract: Vendor and Site
- Oversight; b. Distributed Asset Ledger: Patient Data Access/Transparency) to support future development and implementation for proof of concept.
Episode-of-care payment and comprehensive care payment systems can help providers prevent health problems; avoid the occurrence of acute episodes among individuals who have health conditions; prevent poor outcomes during major acute episodes, such as infections, complications, and hospital readmissions; and reduce the costs of successful treatment.
Using cryptography to keep exchanges secure, blockchain provides a decentralised database, or “digital ledger”, of transactions that everyone on the network can see. This network is essentially a chain of computers that must all approve an exchange before it can be verified and recorded.
A Survey on Decentralized e-health record with health insurance synchronizationIJAEMSJORNAL
In the medical field, electronic health records (EHR) serve a critical function that benefits both healthcare providers and patients. Many cloud-based solutions for medical record exchange have been offered, but the credibility of a third-party cloud service is questioned due to the centralized approach. As a result, a decentralized blockchain system for sharing electronic health records has been established that does not rely on third-party services. Existing services, on the other hand, exclusively collect data from medical tests. They are ineffective at sharing data streams that are continuously created by various sorts of devices. The information gathered is shared with laboratories and medical institutions for future research. Furthermore, current techniques are too rigid to accommodate metadata modification effectively. Decenrod proposes a medical data-sharing scheme that combines blockchain, electronic health records, and a structured peer-to-peer network based on InterPlanetary File System (IPFS) techniques to address the above efficiency issues in existing medical data-sharing and storage services. A session-based healthcare data-sharing strategy has been designed, according to Decenrod, which allows for more flexibility in data sharing. According to the evaluation results, Decenrod can improve efficiency and meet security criteria in data exchange by implementing Decentralized EHR. The information gathered is shared with laboratories and medical institutions for future research.
In this blog, we will explore the far-reaching uses of blockchain and the incredible changes it is bringing about in a range of different business sectors.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. Table of Contents
• What Is Blockchain?
• Blockchain Benefits
• Applications in Life Sciences
• Use Cases
• References
2
3. What is Blockchain?
3
Wikipedia
A blockchain — originally block chain — is a distributed database that maintains a
continuously-growing list of ordered records called blocks. Each block contains a
timestamp and a link to a previous block.
Investopedia
A blockchain is a public ledger of all Bitcoin transactions that have ever been executed. It
is constantly growing as 'completed' blocks are added to it with a new set of recordings.
The blocks are added to the blockchain in a linear, chronological order.
Melanie Swan, Institute for Blockchain Studies
Beyond digitizing money, payments, economics, and finance, blockchains are a
singularity-class technology that enables the secure, trackable, automated coordination
of very large-scale projects, fleets, and swarms. The implication could be an orderly
transition to the automation economy and trust-rich human-machine collaboration in the
digital smart network societies of the future.
Harvard Business Review
A blockchain is a vast, global distributed ledger or database running on millions of
devices and open to anyone, where not just information but anything of value – money,
titles, deeds, music, art, scientific discoveries, intellectual property, and even votes – can
be moved and stored securely and privately.
4. Blockchain Benefits
4
Decentralized Secure Irreversible
Ubiquitous Real Time Visibility
Dis
intermediation
Data is stored across
network – no single
point of failure
Uses unique
public/private key based
on cryptography – a
randomly generated
string of numbers
No centralized official
copy, transactions are
broadcast across the
network
Transactions can not be
reversed once verified
or accepted
Transactions or blocks
are verified in near real
time
Peer-to-peer network,
eliminates
intermediaries in
transactions
Anyone can add or
review blocks from its
inception
Trust &
Consensus
Each contributor is
trusted equally and
collective consensus is
key in verification
Source: See references
5. Personalized medicine
Patient health records
Counterfeit protection
Connectome (personal
mind files)
Smart payments
Beyond the pill
Applications in Life Sciences
5
Preclinical Clinical
Regulatory
Approval
Manufacturing
& Distribution
Patients
Smart IP platform
Peer-Peer IP sharing
Royalty payments &
copyrights mgmt.
Tech transfer offices IP
transactions
Due diligence &
commercialization
IP protection
Secure data transmission
Data integrity
Peer-Peer data sharing
Genomic data sharing
Smart contracts Data sharing & tracking
Verification – smart
contracts
Records mgmt. –
methods & results
IP registration and
exchange
Proof of existence for
patents filing
Smart contracts with external
partners (CRO, etc.)
Digital track and
traceability
Payment transactions
across supply chain
Inventory mgmt. systems
Effective & efficient
targeted recalls
Regulatory compliance
requirements
Value
Chain
Strategic
Value
Levers
• Improved patient engagement
• Better treatment outcomes
• Increased safety
• Increased quality of life
• Continuous manufacturing
• Inventory optimization
• Supply chain visibility
• Faster regulatory approval
• Faster drug discovery
• IP protection and sharing
• Open science framework
• Speed to market
• Cost efficiency
• Data transparency
• Data Integrity
Bilateral communications
with all industry players
Smart contracts and
health insurance
Publications
Blockchain could be used in many applications across the value chain
Source: See references
6. Tech transfer office
submits time stamped
blockchain records as
proof of existence
Use Case: Preclinical
6
Researcher A Researcher B
Trying to find an Cancer drug
in the USA
Around the same time, ‘B’ starts experiments
on similar Cancer drug in Asia
1
2 “A “ uploads the protocol to
blockchain and performs
experiments according to it.
But, experiments are failed and
finds a fault in the protocol
“B” is planning to do similar
experiments and learns that protocol
will not yield positive results from A’s
results and abandons the plan; saving
time and funding
3
3
Tech Transfer Office
Scenario 1: Open Data Sharing
Scenario 2: Proof of Existence
A&B decide to collaborate on the
research, share research funding using
smart contracts on the block chain.
Together they accelerate the discovery
process
4
“A” uploads the drug
discovery (for Influenza)
experimental data on
blockchain after each
experiment. After a couple
of years, ‘A’ invents a lead
molecule
Pharma
2 Tech transfer office decides to
partner with a pharma company
to commercialize drug Pharma and University
negotiate royalty
payments and IP sharing
using smart contracts on
blockchain
4
5
Blockchain
Researcher A
U N I V E R S I T YU N I V E R S I T Y
1
Blockchain
Peer-to-peer network, data storage, and file sharing could accelerate drug discovery and remove many inefficiencies
Source: See references
7. Use Case: Clinical Trials - Smart Contracts
7
• Timothy Nugent et. al. demonstrated the usage
of smart contracts on a private Ethereum
blockchain network for Tamiflu drug clinical trials
management.
• The private network consisted of regulators,
pharma, and contract research organizations
(CROs).
• Smart contracts have two layers – regulatory and
trail.
• The regulatory contract consists of trial
protocol, end point, time lines, and
methods.
• Trial subjects and data are appended to trail
contract, which is owned and managed by
CRO.
• Trial protocol on the network ensures protocol
adherence and timelines. Each trial data entry is
verified, accepted, and stored in all of the nodes
the network.
Trial 1 Trial 2 Trial 3
Regulators (FDA,
MHRA, EMA, etc.)
Blockchain Network
Regulator contract
(trial proposal)
submission
Regulator
contract
approval
Pharma
Companies
Regulator contract, proposal
& trial contract, data
CROs
Trial contract
(subjects,
data)
Regulator contract, proposal
& trial contract, data
1 2 3
4
Source: https://f1000research.com/articles/5-2541/v1
Smart contracts could be a solution to clinical trials issues such as end point switching, data dredging, etc.
8. Use Case: Manufacturing and Distribution - The BlockRx Project
8
• The BlockRx Project: the first Pharma-
Blockchain project, formed in collaboration
with various players of pharma industry.
• The members include providers, regulatory
compliance, legal, scientists, investors,
pharma companies, and tech experts.
• The project aims to develop solutions to
improve drug development life cycle and
pharma supply chain.
• The solutions combine advanced digital ledger
technology (ADLT) and AI to create and
manage digital ledgers of the transaction
across parties.
• These can be used in many applications
including due diligence, inventory
management, recalls process, etc.
Source: Picture taken from http://www.blockrx.com/
Blockchain based supply chain could provide transparency and optimize integrated operations
9. Use Case: Patients - Connectome or Blockchain Thinking
9
Blockchain could enable storing, sharing, and mining of the personal big data such as genomes and
connectomes – blockchain thinking
Personalized medicine
Patient engagement
Market access
Regulatory approvals
Person Thinking Chain
• Storing and processing of personal data
including personal connectome files, digital
identities such as Facebook and LinkedIn,
physical property registrations, etc.
Health Data Commons
• Public sharing of personal health data,
EMRs, quantified self-tracking data,
and mental performance data
Blockchain Based Advocates
• Digital mind files and smart contracts on
the blockchain invoke advocacy services
on one’s behalf and act as third party
mediators
Source: http://www.the-blockchain.com/docs/Blockchain%20Thinking%20-%20The%20Brain%20as%20a%20DAC%20-%20Decentralized%20Autonomous%20Organization.pdf
Benefits to PharmaSome futuristic applications
