Blockchain is an immutable and secure distributed ledger that allows for a single version of truth across multiple parties. It is the technology that underlies Bitcoin, which is a cryptocurrency that solves issues with traditional banking like transaction fees, fake currencies, and transaction times. Bitcoin transactions are recorded on the blockchain in an immutable way that prevents hacking. Blockchain has various use cases in healthcare like creating longitudinal patient records by compiling medical data from different providers on an interoperable ledger, improving master patient indices to reduce duplicate records, enabling automatic claims adjudication, and improving supply chain management through smart contracts.