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ORAL PATHOLOGY
Basal Cell Carcinoma
Case-Presentation
Case
65-year-old male patient. Smoker for 30 years (7
cigarettes/day).
Diabetic and hypertensive on medications.
Works in the farm from 6 am to 4 pm since he was 18
years old.
Non-painful lesion of 4 months duration.
“
History Analysis
▸Age : 65 years old
▸Gender : male
▸Chief complaint: Non-painful lesion of 4
months duration.
▸Medical status: Diabetic and hypertensive
on medications.
▸Smoker for 30 years (7 cigarettes/day).
Clinical Interpretation
Colored clinical photograph showing lateral
side of the patient’s nose.
There is round, pearly, flesh-colored
papule with Rolled (raised) border and
blood vessels over the surface
Differential diagnosis based on the
clinical features
Basal cell carcinoma
Actinic keratosis
Squamous cell
carcinoma
Bowen
disease
Fibrous
papule
Basal cell carcinoma
Lorem Ipsum
▸Inclusion criteria:
▸Erythematous lesion flush in skin surface
▸Indurated pearly papule or nodule with
telangiectatic vessels over its surface.
▸It is usually painless
▸Older patient
▸Male
▸long-term exposure to the sun Works in the farm from 6 am to 4 pm
since he was 18 years old
- Inclusion criteria:
- Result from prolonged sun
exposure. The common areas
where these patches are
found are face, ears, lips,
back of the hands, forearms,
neck or scalp.
- Dry, rough scaly patch
- Flat to slightly elevated
▸(SCC) is commonly a well-
defined, red, scaling, thickened
bump .
▸It may ulcerate and bleed
Inclusion criteria:
 It can occur on any part of the body,
but are most common on areas that are
exposed to the sun such as the ears,
lips, nose, face and tops of the hands.
 Builders, farmers, sailors and people
who often use sun-beds can develop
SCC.
 Most SCC are not painful.
 Older people.
Inclusion criteria:
 It is a rare skin disorder.
 The biggest risk factor for
Bowen’s disease is exposure
to the sun over a long time.
 Lesions are usually not
painful or may not be
associated with any
symptoms (asymptomatic).
 The disorder usually affects
older adults.
Reddish scaly flat patch on the skin
that has clear edges
Inclusion criteria:
▸It is a common benign
lesion usually in the nose.
▸Often less than 5 mm in
diameter
 A dome-shaped, shiny papule.
 Skin color.
 Arises mainly in young adults.
Definitive Diagnosis:
Basal Cell Carcinoma
BCC is most common malignancy of
skin, constitutes ~80% of all skin
cancers.
Usually in patients >40 years of age.
More often in men than in women
(male : female = 1.6:1)
BCC is locally invasive, slowely
spreading, primary epithelial
malignancy thst arises from basal cell
layer
Types of BCC
Nodular basal-cell
carcinoma
Pigmented basal-
cell carcinoma
Rodent ulcer
Superficial basal-
cell carcinoma
Basal Cell
Carcinoma
peripheral
palisading
Rim of
mucin
Dermal
nests of
basaloid
cells
Retracted
stroma
around
malignant
mass
Nests of basal cells
Squamous
epithelium
Treatment
Photodynamic
Therapy
Surgical
excision
&
Mohs
micrographic
surgery
Electrodessica-
tion
&
curettage
cosmetic83%
-They found there were 79 of total
193 patients cases of basal cell
carcinoma (BCC) (41%).
- The male to female ratio for all
cancer was 1.6:1. The peak
age distribution was in the 70-
80-years group.
CONCLUSIONS
The most common skin cancers
seen are BCC and SCC followed
by Kaposi's sarcoma.
In a US population-based
study, indoor tanning was
associated with an elevated
risk of basal cell carcinomas
occurring at or before the age
of 50 years, with an increasing
trend in risk with younger age
at exposure among
adolescents and young adults.
References
▸Neville, Brad W et al. Oral And Maxillofacial Pathology. 3rd ed.
Print.
▸Regezi, Joseph A. Oral Pathology. 6th ed. Elsevier Health
Sciences, 2012. Print.
▸Al-Maghrabi, Jaudah, Abdulhameed Al-Ghamdi, and Howaida
Elhakeem. "Pattern Of Skin Cancer In Southwestern Saudi
Arabia.". Smj.org.sa. N.p., 2017. Web. 18 Feb. 2017.
▸Karagas, Margaret R., et al. "Early-onset basal cell carcinoma
and indoor tanning: a population-based study." Pediatrics 134.1
(2014): e4-e12.
"Basal Cell Carcinoma (BCC)". Pathologyoutlines.com. N.p., 2017.
Web. 18 Feb. 2017.
"Actinic Keratosis (AK) - Skincancer.Org". Skincancer.org. N.p.,
2017. Web. 18 Feb. 2017.
Matei, C., et al. "Photodynamic therapy in the treatment of
basal cell carcinoma." Journal of medicine and life 6.1 (2013):
50.
THANKS!
Any questions?

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Basal cell carcinoma

  • 1. ORAL PATHOLOGY Basal Cell Carcinoma Case-Presentation
  • 2. Case 65-year-old male patient. Smoker for 30 years (7 cigarettes/day). Diabetic and hypertensive on medications. Works in the farm from 6 am to 4 pm since he was 18 years old. Non-painful lesion of 4 months duration.
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  • 5. History Analysis ▸Age : 65 years old ▸Gender : male ▸Chief complaint: Non-painful lesion of 4 months duration. ▸Medical status: Diabetic and hypertensive on medications. ▸Smoker for 30 years (7 cigarettes/day).
  • 6. Clinical Interpretation Colored clinical photograph showing lateral side of the patient’s nose. There is round, pearly, flesh-colored papule with Rolled (raised) border and blood vessels over the surface
  • 7. Differential diagnosis based on the clinical features Basal cell carcinoma Actinic keratosis Squamous cell carcinoma Bowen disease Fibrous papule
  • 8. Basal cell carcinoma Lorem Ipsum ▸Inclusion criteria: ▸Erythematous lesion flush in skin surface ▸Indurated pearly papule or nodule with telangiectatic vessels over its surface. ▸It is usually painless ▸Older patient ▸Male ▸long-term exposure to the sun Works in the farm from 6 am to 4 pm since he was 18 years old
  • 9. - Inclusion criteria: - Result from prolonged sun exposure. The common areas where these patches are found are face, ears, lips, back of the hands, forearms, neck or scalp. - Dry, rough scaly patch - Flat to slightly elevated
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  • 11. ▸(SCC) is commonly a well- defined, red, scaling, thickened bump . ▸It may ulcerate and bleed Inclusion criteria:  It can occur on any part of the body, but are most common on areas that are exposed to the sun such as the ears, lips, nose, face and tops of the hands.  Builders, farmers, sailors and people who often use sun-beds can develop SCC.  Most SCC are not painful.  Older people.
  • 12. Inclusion criteria:  It is a rare skin disorder.  The biggest risk factor for Bowen’s disease is exposure to the sun over a long time.  Lesions are usually not painful or may not be associated with any symptoms (asymptomatic).  The disorder usually affects older adults. Reddish scaly flat patch on the skin that has clear edges
  • 13. Inclusion criteria: ▸It is a common benign lesion usually in the nose. ▸Often less than 5 mm in diameter  A dome-shaped, shiny papule.  Skin color.  Arises mainly in young adults.
  • 15. BCC is most common malignancy of skin, constitutes ~80% of all skin cancers. Usually in patients >40 years of age. More often in men than in women (male : female = 1.6:1) BCC is locally invasive, slowely spreading, primary epithelial malignancy thst arises from basal cell layer Types of BCC Nodular basal-cell carcinoma Pigmented basal- cell carcinoma Rodent ulcer Superficial basal- cell carcinoma Basal Cell Carcinoma
  • 17. Nests of basal cells Squamous epithelium
  • 19. -They found there were 79 of total 193 patients cases of basal cell carcinoma (BCC) (41%). - The male to female ratio for all cancer was 1.6:1. The peak age distribution was in the 70- 80-years group. CONCLUSIONS The most common skin cancers seen are BCC and SCC followed by Kaposi's sarcoma.
  • 20. In a US population-based study, indoor tanning was associated with an elevated risk of basal cell carcinomas occurring at or before the age of 50 years, with an increasing trend in risk with younger age at exposure among adolescents and young adults.
  • 21. References ▸Neville, Brad W et al. Oral And Maxillofacial Pathology. 3rd ed. Print. ▸Regezi, Joseph A. Oral Pathology. 6th ed. Elsevier Health Sciences, 2012. Print. ▸Al-Maghrabi, Jaudah, Abdulhameed Al-Ghamdi, and Howaida Elhakeem. "Pattern Of Skin Cancer In Southwestern Saudi Arabia.". Smj.org.sa. N.p., 2017. Web. 18 Feb. 2017. ▸Karagas, Margaret R., et al. "Early-onset basal cell carcinoma and indoor tanning: a population-based study." Pediatrics 134.1 (2014): e4-e12. "Basal Cell Carcinoma (BCC)". Pathologyoutlines.com. N.p., 2017. Web. 18 Feb. 2017. "Actinic Keratosis (AK) - Skincancer.Org". Skincancer.org. N.p., 2017. Web. 18 Feb. 2017. Matei, C., et al. "Photodynamic therapy in the treatment of basal cell carcinoma." Journal of medicine and life 6.1 (2013): 50.