Download to read offline
More Related Content
Similar to Barrett’s esophagus.pptx a brief discription
Barrett’s esophagus.pptx a brief discription
- 1. BARRETT’S ESOPHAGUS Presented by – ALOKKUMAR YADAV ROLL NO. 14
- 2. INDEX INTRODUCTION ASSOCIATEDRISK FACTORS PATHOGENESIS SIGN AND SYMPTOMS DIAGNOSIS MANAGEMENT
- 3. INTRODUCTION Barrett esophagus isa complication of chronic GERD that is characterised by a intestinal metaplasia within the esophageal squamous mucosa and is associated with an increased risk of cancer. Also called as – Barrett syndrome/ Columnar Lined Lower Oesophagus
- 4. ASSOCIATED RISK FACTORS 10%cases of symptomatic GERD 2% general population More common in white males ( 40-60 yrs ) Obese population
- 5. PATHOGENESIS Chronic GERD Incresed acid exposure ESOPHAGEAL MUCOSAL INJURY ANDSQUAMOUS EPITHELIAL DAMAGE Acute and chronic inflammatory changes Reflux esophagitis Recovery ( metaplastic changes ) BARRETT’S ESOPHAGUS MAY LEAD TO ADENOCARCINOM A OF THE ESOPHAGUS DYSPLASIA
- 7. MORPHOLOGY Red velvety mucosaextending upward from the gastroesophageal junction. Normal squamous epithelial cell changes into goblet cell . Types 1. Long segment (>3 cm ) 2. Short segment (<3 cm )
- 8. SIGN AND SYMPTOMS Frequentand longstanding heartburn Dysphagia Hematemesis Pain under the breastbone Weight loss
- 9. DIAGNOSTIC APPROACHES ENDOSCOPY (esophago-gastro-duodenoscopy) BIOPSY( presence of goblet cell is seen )
- 10. MANAGEMENT Surveillance by periodicendoscopy with biopsy. PPI’S and NSAIDS Esophagectomy Mucosal resection Photodynamic therapy endoscopic mucosectomy
- 11.
- 12. SUMMARY Barrett esophagus developsin patient with chronic GERD and Represents columnar metaplasia of the esophagial squamous mucosa Barrett esophagus is a risk factor for development of esophageal carcinoma
- 13. REFERENCES Pathologic basis ofdisease by ROBBINS AND COTRAN tenth edition volume 2 . NATIONAL INSTITUTE OF HEALTH ( niddk.nih.gov) Image courtsy – PINTEREST
- 14.