Autoimmune disease
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An autoimmune disease is a condition in which your immune system mistakenly attacks your body. In an autoimmune disease, the immune system mistakes part of your body, like your joints or skin, as foreign.
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Autoimmune disease
The ppt covers the topics-
1. Introduction to the topic
2. Types of autoimmune diseases
3. Addison's Disease
4. Grave's Disease
5. Hashimoto's disease
6. Myasthenia gravis
7. Multiple sclerosis
8. Pernicious anaemia
9. Rheumatoid arthritis
10. Systemic lupus erythematosus (SLE)
Autoimmune disease
An autoimmune disease occurs when the immune system mistakenly attacks and damages healthy body tissues. Examples include rheumatoid arthritis, type 1 diabetes, and lupus. Symptoms vary by disease but commonly include fatigue, pain, fever, and inflammation. Current treatments aim to suppress the immune system's misdirected response through drugs, surgery, or targeted therapies.
Autoimmune diseases
The document discusses several autoimmune diseases including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, Graves' disease, and systemic lupus erythematosus. It provides information on the causes, symptoms, diagnosis, and treatment for each disease. The diseases result from the immune system mistakenly attacking healthy body cells and tissues. There are over 100 types of autoimmune diseases that can affect many organs and bodily systems.
Organ specific autoimmune disorders
This document summarizes several organ-specific autoimmune disorders:
1. Hashimoto's thyroiditis causes inflammation and damage to the thyroid gland through autoantibodies against thyroid proteins. This leads to hypothyroidism.
2. Autoimmune anemias include pernicious anemia caused by intrinsic factor antibodies impairing vitamin B12 absorption, and autoimmune hemolytic anemia where antibodies lyse or phagocytose red blood cells.
3. Goodpasture's syndrome features antibodies against lung and kidney basement membranes, activating complement and damaging these organs through inflammation.
4. Type 1 diabetes results from an autoimmune destruction of insulin-producing pancreatic beta cells by cytotoxic T cells and
Auto immune diseases
AUTOIMMUNE DISEASES IS DEFINED AS THE CONDITION WERE OUR OWN IMMUNE SYSTEM FAILS TO DISCRIMINATE BETWEEN SELF AND NON-SELF CELLS.
Autoimmune disease
This presentation contains principle, etiology and, clinical and lab diagnosis of various autoimmune disease.
Autoimmune disease and autoimmunity
Autoimmunity occurs when the immune system mistakenly attacks and damages healthy body tissues. This can lead to autoimmune diseases, which affect around 5% of people in developed countries. There are two main types of autoimmune diseases - organ-specific diseases that target a single organ, and systemic diseases that affect multiple organs. Some common autoimmune diseases include chronic thyroiditis, pernicious anemia, autoimmune hemolytic anemia, rheumatoid arthritis, multiple sclerosis, and systemic lupus erythematosus. Many autoimmune diseases are treated with steroids or other immunosuppressant drugs to reduce immune system activity.
Introduction Autoimmune Disease by Dr. Kelly Cobb
The immune system represents an interface between a constant ever-changing external environment and an internal system that is striving to maintain homeostasis and defend its boundaries from harmful foreign invaders.
Recommended
Autoimmune disease
The ppt covers the topics-
1. Introduction to the topic
2. Types of autoimmune diseases
3. Addison's Disease
4. Grave's Disease
5. Hashimoto's disease
6. Myasthenia gravis
7. Multiple sclerosis
8. Pernicious anaemia
9. Rheumatoid arthritis
10. Systemic lupus erythematosus (SLE)
Autoimmune disease
An autoimmune disease occurs when the immune system mistakenly attacks and damages healthy body tissues. Examples include rheumatoid arthritis, type 1 diabetes, and lupus. Symptoms vary by disease but commonly include fatigue, pain, fever, and inflammation. Current treatments aim to suppress the immune system's misdirected response through drugs, surgery, or targeted therapies.
Autoimmune diseases
The document discusses several autoimmune diseases including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, Graves' disease, and systemic lupus erythematosus. It provides information on the causes, symptoms, diagnosis, and treatment for each disease. The diseases result from the immune system mistakenly attacking healthy body cells and tissues. There are over 100 types of autoimmune diseases that can affect many organs and bodily systems.
Organ specific autoimmune disorders
This document summarizes several organ-specific autoimmune disorders:
1. Hashimoto's thyroiditis causes inflammation and damage to the thyroid gland through autoantibodies against thyroid proteins. This leads to hypothyroidism.
2. Autoimmune anemias include pernicious anemia caused by intrinsic factor antibodies impairing vitamin B12 absorption, and autoimmune hemolytic anemia where antibodies lyse or phagocytose red blood cells.
3. Goodpasture's syndrome features antibodies against lung and kidney basement membranes, activating complement and damaging these organs through inflammation.
4. Type 1 diabetes results from an autoimmune destruction of insulin-producing pancreatic beta cells by cytotoxic T cells and
Auto immune diseases
AUTOIMMUNE DISEASES IS DEFINED AS THE CONDITION WERE OUR OWN IMMUNE SYSTEM FAILS TO DISCRIMINATE BETWEEN SELF AND NON-SELF CELLS.
Autoimmune disease
This presentation contains principle, etiology and, clinical and lab diagnosis of various autoimmune disease.
Autoimmune disease and autoimmunity
Autoimmunity occurs when the immune system mistakenly attacks and damages healthy body tissues. This can lead to autoimmune diseases, which affect around 5% of people in developed countries. There are two main types of autoimmune diseases - organ-specific diseases that target a single organ, and systemic diseases that affect multiple organs. Some common autoimmune diseases include chronic thyroiditis, pernicious anemia, autoimmune hemolytic anemia, rheumatoid arthritis, multiple sclerosis, and systemic lupus erythematosus. Many autoimmune diseases are treated with steroids or other immunosuppressant drugs to reduce immune system activity.
Introduction Autoimmune Disease by Dr. Kelly Cobb
The immune system represents an interface between a constant ever-changing external environment and an internal system that is striving to maintain homeostasis and defend its boundaries from harmful foreign invaders.
Auto immunity
Autoimmunity results from a failure of the immune system to distinguish self from non-self. There are several mechanisms that can cause this including genetic factors, immunological issues, and infections. Autoimmune diseases can be organ-specific, where autoantibodies attack a single organ, or non-organ specific which causes systemic damage. Common autoimmune diseases include systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis, and Sjogren's syndrome. Tissue damage in autoimmune diseases is typically caused by type II or type III hypersensitivity reactions.
Autoimmune disorders
This document provides information on autoimmune disorders like rheumatoid arthritis and systemic lupus erythematosus. It explains that autoimmunity occurs when the immune system attacks the body's own cells, causing diseases. Rheumatoid arthritis specifically causes joint inflammation and damage through autoantibodies attacking joint linings. Systemic lupus erythematosus more broadly attacks tissues, producing symptoms like rashes, fever, and kidney issues. Both have no cure but can be treated to reduce immune response and manage symptoms.
Autoimmune disease mechanisms
The document discusses mechanisms of autoimmune disease. It begins by explaining that autoimmune disease occurs when the immune system attacks the body's own tissues. It then discusses several factors that can contribute to autoimmune diseases, including genetics, environment, hormones, diet, toxins/drugs, and infections. Common mechanisms by which autoimmune diseases develop include antibody-mediated damage and cell-mediated damage through immune cells like T cells and macrophages.
Autoimmunity and diseses
The term Autoimmunity is coined by Paul Enrlich.
Autoimmunity is defined as humoral or cell mediated immune response against self antigens
Autoimmune diseases are a group of disorders caused by immune response to self antigens.
3. autoimmune disorders dr. sinhasan, mdzah
This document discusses autoimmune diseases, which constitute 1-2% of the population. It defines pathologic autoimmunity and lists common organ-specific autoimmune diseases. The mechanisms of self-tolerance and its breakdown leading to autoimmunity are described. In-depth details provided on Systemic Lupus Erythematosus (SLE) include diagnostic criteria, associated autoantibodies, clinical features, pathology, and treatment approaches.
Autoimmune Disease By Bishajit debnath
Autoimmune diseases arise when the immune system mistakenly attacks and damages healthy body tissues. There are over 80 known autoimmune diseases that can affect multiple organs and tissues. Common autoimmune diseases include type 1 diabetes, rheumatoid arthritis, and multiple sclerosis. The causes of autoimmune diseases are complex and not fully understood but involve genetic and environmental factors. While there is no cure for most autoimmune diseases, treatment options aim to reduce symptoms by suppressing the immune system or controlling inflammation.
Autoimmunity
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues. Any disease that results from such an aberrant immune response is termed an "autoimmune disease".
Autoimmune Disorders
Multiple Sclerosis (MS) and Myasthenia Gravis (MG) are autoimmune disorders where the immune system attacks the body's own healthy cells. MS affects the central nervous system by damaging the protective myelin sheath surrounding nerve fibers, while MG affects the neuromuscular junction by blocking or destroying acetylcholine receptors. Common symptoms of MS include sensory issues, muscle weakness, fatigue and vision problems. MG symptoms often begin with eye weakness and drooping eyelids and may progress to generalized weakness. While there is no cure for either condition, treatments can help manage symptoms and delay disease progression.
Auto immune disease
This document presents information about autoimmune diseases from MD. Zahirul Islam. It defines autoimmune disease as a condition where the body produces antibodies that attack its own tissues, leading to damage. It provides examples of common autoimmune diseases like lupus, rheumatoid arthritis, and diabetes. The document notes there are two main types - systemic disorders involving non-specific autoantibodies and local disorders targeting specific tissues. It discusses the most common organs and tissues affected by autoimmune diseases and describes methods of diagnosis and treatment options for some conditions.
Autoimmunediseases 110703093122-phpapp02
This document discusses autoimmune diseases, including their causes, classification, and examples. Autoimmune diseases occur when the immune system attacks the body's own tissues. They are broadly classified into three groups: haemolytic, localized, and systemic. Examples provided include Graves' disease, Addison's disease, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, Hashimoto's thyroiditis, and Sjögren's syndrome. The causes of autoimmune diseases include sequestered antigens, neoantigens, loss of tolerance, and cross-reacting antigens.
Autoim lecture slides
Autoimmunity occurs when the immune system loses tolerance to its own tissues and mounts an immune response against them. There are several potential mechanisms for this loss of tolerance, including molecular mimicry between foreign and self antigens, sequestered self antigens being exposed to the immune system, and failures of regulatory mechanisms that normally suppress autoreactive immune cells. Autoimmune diseases result when this autoreactivity causes tissue damage. Examples include diseases caused by autoantibodies like rheumatoid arthritis, Graves' disease, and Hashimoto's thyroiditis, as well as those caused by autoreactive T cells like multiple sclerosis and insulin-dependent diabetes.
Autoimmune DIseases : Types, Mechanism, Diagnosis, Treatment
This is a presentation useful to learners of immunology as well as acadeicians. Useful in undergraduate as well as postgraduate courses. NEET students/Teachers can also get advantage of it.
Autoimmune disorders and immunity
The document discusses autoimmune disorders and summarizes key points about Graves' disease. It explains that autoimmune disorders occur when the immune system mistakenly attacks healthy body tissue. Graves' disease is described as an autoimmune disorder where antibodies cause the thyroid gland to produce excess hormones, leading to hyperthyroidism. The symptoms and common treatments are outlined, noting Graves' disease can often be managed after diagnosis.
auto immune disorder seminar
This document provides information on autoimmune disorders, including:
- Causes of autoimmunity include sequestered antigens, altered antigens, loss of immunoregulation, and loss of self-tolerance.
- Common autoimmune diseases discussed include systemic lupus erythematosus and systemic sclerosis.
- For systemic lupus erythematosus, clinical manifestations, etiology, pathology, and treatment are summarized. Oral manifestations including bleeding and ulcers are also noted.
- Systemic sclerosis causes fibrosis of the skin, subcutaneous tissue, muscles and internal organs. Its etiology is unclear but involves genetic and environmental factors.
AUTOIMMUNITY
This document discusses autoimmunity, including its definition as an inappropriate immune response against self cells/tissues due to self-tolerance failure. Various triggers are described, such as genetic factors like certain HLA alleles associated with diseases, environmental factors like molecular mimicry between pathogens and self-antigens, and non-genetic host factors including immunodeficiencies. Numerous autoimmune diseases are detailed along with their antibody targets and clinical features. Diagnosis involves clinical exams, labs to detect autoantibodies, and biopsies. Treatment focuses on reducing inflammation through steroids, blocking cytokines/integrins/B cells, or more extreme measures like immunosuppressants.
Upload slide
This document outlines Saurabh Pal's presentation on autoimmune disorders. It begins with a brief history of autoimmunity, noting some key discoveries in the 1960s and 1970s. It then discusses what causes the immune system to attack the body, including possible genetic, environmental, and molecular mimicry mechanisms. The presentation covers the classification of autoimmune disorders into localized, systemic, and hemolytic types and provides examples such as rheumatoid arthritis, Graves' disease, and Addison's disease. It discusses toxicology factors that may contribute to autoimmunity and current treatment approaches like immunosuppressive drugs and plasmapheresis. The presentation concludes by noting recent advances in monoclonal antibody therapies and nanoparticle drug delivery for auto
autoimmune dis pathmorph
This document discusses autoimmune diseases, including their mechanisms, features, and different types. It begins with an introduction to autoimmunity and immunological tolerance. It then covers the general mechanisms of autoimmunity, including genetic and environmental triggers. The key features of autoimmune diseases are progressive damage, clinical/pathological manifestations tied to the immune response, and clinical overlaps between diseases. Specific diseases discussed include systemic lupus erythematosus, its diagnostic criteria and morphology, and other systemic diseases like Sjogren's syndrome and systemic sclerosis.
Autoimmune diseases overview
This document discusses autoimmune rheumatic diseases and related conditions. It notes that autoimmunity can affect any organ system in the human body and lists several specific autoimmune diseases as examples. The document classifies autoimmune diseases as either organ-specific or systemic. It discusses historical evidence of autoimmune diseases. The document outlines multiple cell types and cytokine signaling pathways involved in chronic inflammatory arthritis. It states that rheumatoid arthritis and systemic lupus erythematosus are systemic inflammatory diseases. Therapeutic strategies discussed include reagents that reduce inflammation like NSAIDs and steroids, as well as disease-modifying drugs and biological therapeutics that target specific proteins or pathways.
Autoimmunity
This document discusses autoimmunity and autoimmune diseases. It begins by explaining how the immune system can mistakenly attack self-antigens, leading to autoimmunity. Several organ-specific and systemic autoimmune diseases are described in detail, including how they are mediated by direct cellular damage, stimulating or blocking autoantibodies. Current treatments aim to suppress the immune system generally but do not cure the underlying condition. Experimental therapies discussed include T-cell vaccination, peptide blockade of MHC molecules, and monoclonal antibodies.
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Auto immunity
Autoimmunity results from a failure of the immune system to distinguish self from non-self. There are several mechanisms that can cause this including genetic factors, immunological issues, and infections. Autoimmune diseases can be organ-specific, where autoantibodies attack a single organ, or non-organ specific which causes systemic damage. Common autoimmune diseases include systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis, and Sjogren's syndrome. Tissue damage in autoimmune diseases is typically caused by type II or type III hypersensitivity reactions.
Autoimmune disorders
This document provides information on autoimmune disorders like rheumatoid arthritis and systemic lupus erythematosus. It explains that autoimmunity occurs when the immune system attacks the body's own cells, causing diseases. Rheumatoid arthritis specifically causes joint inflammation and damage through autoantibodies attacking joint linings. Systemic lupus erythematosus more broadly attacks tissues, producing symptoms like rashes, fever, and kidney issues. Both have no cure but can be treated to reduce immune response and manage symptoms.
Autoimmune disease mechanisms
The document discusses mechanisms of autoimmune disease. It begins by explaining that autoimmune disease occurs when the immune system attacks the body's own tissues. It then discusses several factors that can contribute to autoimmune diseases, including genetics, environment, hormones, diet, toxins/drugs, and infections. Common mechanisms by which autoimmune diseases develop include antibody-mediated damage and cell-mediated damage through immune cells like T cells and macrophages.
Autoimmunity and diseses
The term Autoimmunity is coined by Paul Enrlich.
Autoimmunity is defined as humoral or cell mediated immune response against self antigens
Autoimmune diseases are a group of disorders caused by immune response to self antigens.
3. autoimmune disorders dr. sinhasan, mdzah
This document discusses autoimmune diseases, which constitute 1-2% of the population. It defines pathologic autoimmunity and lists common organ-specific autoimmune diseases. The mechanisms of self-tolerance and its breakdown leading to autoimmunity are described. In-depth details provided on Systemic Lupus Erythematosus (SLE) include diagnostic criteria, associated autoantibodies, clinical features, pathology, and treatment approaches.
Autoimmune Disease By Bishajit debnath
Autoimmune diseases arise when the immune system mistakenly attacks and damages healthy body tissues. There are over 80 known autoimmune diseases that can affect multiple organs and tissues. Common autoimmune diseases include type 1 diabetes, rheumatoid arthritis, and multiple sclerosis. The causes of autoimmune diseases are complex and not fully understood but involve genetic and environmental factors. While there is no cure for most autoimmune diseases, treatment options aim to reduce symptoms by suppressing the immune system or controlling inflammation.
Autoimmunity
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues. Any disease that results from such an aberrant immune response is termed an "autoimmune disease".
Autoimmune Disorders
Multiple Sclerosis (MS) and Myasthenia Gravis (MG) are autoimmune disorders where the immune system attacks the body's own healthy cells. MS affects the central nervous system by damaging the protective myelin sheath surrounding nerve fibers, while MG affects the neuromuscular junction by blocking or destroying acetylcholine receptors. Common symptoms of MS include sensory issues, muscle weakness, fatigue and vision problems. MG symptoms often begin with eye weakness and drooping eyelids and may progress to generalized weakness. While there is no cure for either condition, treatments can help manage symptoms and delay disease progression.
Auto immune disease
This document presents information about autoimmune diseases from MD. Zahirul Islam. It defines autoimmune disease as a condition where the body produces antibodies that attack its own tissues, leading to damage. It provides examples of common autoimmune diseases like lupus, rheumatoid arthritis, and diabetes. The document notes there are two main types - systemic disorders involving non-specific autoantibodies and local disorders targeting specific tissues. It discusses the most common organs and tissues affected by autoimmune diseases and describes methods of diagnosis and treatment options for some conditions.
Autoimmunediseases 110703093122-phpapp02
This document discusses autoimmune diseases, including their causes, classification, and examples. Autoimmune diseases occur when the immune system attacks the body's own tissues. They are broadly classified into three groups: haemolytic, localized, and systemic. Examples provided include Graves' disease, Addison's disease, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, Hashimoto's thyroiditis, and Sjögren's syndrome. The causes of autoimmune diseases include sequestered antigens, neoantigens, loss of tolerance, and cross-reacting antigens.
Autoim lecture slides
Autoimmunity occurs when the immune system loses tolerance to its own tissues and mounts an immune response against them. There are several potential mechanisms for this loss of tolerance, including molecular mimicry between foreign and self antigens, sequestered self antigens being exposed to the immune system, and failures of regulatory mechanisms that normally suppress autoreactive immune cells. Autoimmune diseases result when this autoreactivity causes tissue damage. Examples include diseases caused by autoantibodies like rheumatoid arthritis, Graves' disease, and Hashimoto's thyroiditis, as well as those caused by autoreactive T cells like multiple sclerosis and insulin-dependent diabetes.
Autoimmune DIseases : Types, Mechanism, Diagnosis, Treatment
This is a presentation useful to learners of immunology as well as acadeicians. Useful in undergraduate as well as postgraduate courses. NEET students/Teachers can also get advantage of it.
Autoimmune disorders and immunity
The document discusses autoimmune disorders and summarizes key points about Graves' disease. It explains that autoimmune disorders occur when the immune system mistakenly attacks healthy body tissue. Graves' disease is described as an autoimmune disorder where antibodies cause the thyroid gland to produce excess hormones, leading to hyperthyroidism. The symptoms and common treatments are outlined, noting Graves' disease can often be managed after diagnosis.
auto immune disorder seminar
This document provides information on autoimmune disorders, including:
- Causes of autoimmunity include sequestered antigens, altered antigens, loss of immunoregulation, and loss of self-tolerance.
- Common autoimmune diseases discussed include systemic lupus erythematosus and systemic sclerosis.
- For systemic lupus erythematosus, clinical manifestations, etiology, pathology, and treatment are summarized. Oral manifestations including bleeding and ulcers are also noted.
- Systemic sclerosis causes fibrosis of the skin, subcutaneous tissue, muscles and internal organs. Its etiology is unclear but involves genetic and environmental factors.
AUTOIMMUNITY
This document discusses autoimmunity, including its definition as an inappropriate immune response against self cells/tissues due to self-tolerance failure. Various triggers are described, such as genetic factors like certain HLA alleles associated with diseases, environmental factors like molecular mimicry between pathogens and self-antigens, and non-genetic host factors including immunodeficiencies. Numerous autoimmune diseases are detailed along with their antibody targets and clinical features. Diagnosis involves clinical exams, labs to detect autoantibodies, and biopsies. Treatment focuses on reducing inflammation through steroids, blocking cytokines/integrins/B cells, or more extreme measures like immunosuppressants.
Upload slide
This document outlines Saurabh Pal's presentation on autoimmune disorders. It begins with a brief history of autoimmunity, noting some key discoveries in the 1960s and 1970s. It then discusses what causes the immune system to attack the body, including possible genetic, environmental, and molecular mimicry mechanisms. The presentation covers the classification of autoimmune disorders into localized, systemic, and hemolytic types and provides examples such as rheumatoid arthritis, Graves' disease, and Addison's disease. It discusses toxicology factors that may contribute to autoimmunity and current treatment approaches like immunosuppressive drugs and plasmapheresis. The presentation concludes by noting recent advances in monoclonal antibody therapies and nanoparticle drug delivery for auto
autoimmune dis pathmorph
This document discusses autoimmune diseases, including their mechanisms, features, and different types. It begins with an introduction to autoimmunity and immunological tolerance. It then covers the general mechanisms of autoimmunity, including genetic and environmental triggers. The key features of autoimmune diseases are progressive damage, clinical/pathological manifestations tied to the immune response, and clinical overlaps between diseases. Specific diseases discussed include systemic lupus erythematosus, its diagnostic criteria and morphology, and other systemic diseases like Sjogren's syndrome and systemic sclerosis.
Autoimmune diseases overview
This document discusses autoimmune rheumatic diseases and related conditions. It notes that autoimmunity can affect any organ system in the human body and lists several specific autoimmune diseases as examples. The document classifies autoimmune diseases as either organ-specific or systemic. It discusses historical evidence of autoimmune diseases. The document outlines multiple cell types and cytokine signaling pathways involved in chronic inflammatory arthritis. It states that rheumatoid arthritis and systemic lupus erythematosus are systemic inflammatory diseases. Therapeutic strategies discussed include reagents that reduce inflammation like NSAIDs and steroids, as well as disease-modifying drugs and biological therapeutics that target specific proteins or pathways.
Autoimmunity
This document discusses autoimmunity and autoimmune diseases. It begins by explaining how the immune system can mistakenly attack self-antigens, leading to autoimmunity. Several organ-specific and systemic autoimmune diseases are described in detail, including how they are mediated by direct cellular damage, stimulating or blocking autoantibodies. Current treatments aim to suppress the immune system generally but do not cure the underlying condition. Experimental therapies discussed include T-cell vaccination, peptide blockade of MHC molecules, and monoclonal antibodies.
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Autoimmune DIseases : Types, Mechanism, Diagnosis, Treatment
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There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
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Autoimmune disease
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