5/29/2017 1
Presented By:
Phr. Deepa kumari karn
CONTENTIntroduction
Prevalence
Symptoms
Social difficulties
Communication difficulties
Unusual behaviors
Associated symptoms
Causes
Genetic disorder
Brain abnormalities
Infections and drugs5/29/2017 2
 Treatment
Therapy and training approaches
Medications
 Diagnosing Autism and related disorders
Asperger’s Syndrome
Perasive development disorder not otherwise
specified
 Education of children with Autism
 Life of adults with Autism
 Controversies
 Famous people with unspecified
forms of autism
5/29/2017 3
5/29/2017 4
Disorder that affects the social, emotional
and behavioral development of children
Marked by serious difficulties in
interacting and communicating with other
people
American Psychiatrist Leo Kanner first
described this disorder in 1943.
It may be related to abnormal response to
sensory input
Autism is at least 4 times more common in
boys than in girls
Autism comes from Greek word Auto; “self”
means an abnormal withdrawal from the world
outside oneself
Causes of Autism remain a major area of
research and controversy
 There is no cure for Autism but some T/T
and therapies can lessen the symptoms
5/29/2017 5
PREVALENCE
The number of children diagnosed with
Autism has increased since the 1990s
Most recent estimates suggest that Autism
occurs in approximately 1 in 500 children and
that 1 in 150 children may be on “Autism
spectrum”
Girls with Autism, however tend to show more
sever symptoms and mental impairment
5/29/2017 6
MECHANISM
How Autism occurs is not well understood.
It’s mechanism is divied into two main
areas;-
1) Pathophysiology
2) Neurophysiology
 Pathophysiology;-
 Linkes the Brain Structure and
process associated with Autism
5/29/2017 7
5/29/2017 8
Fig;-Pathophysiology
 Neurophysiology;-
 Two major categories of cognitive theories
have been proposed about the links between
autistic brains and behavior
The first category focuses on deficits in
social cognitive. According to this theory;-
Autistic child can develop internal
rules of operation to handle events
inside the brains- but are less
effective at empathizing by
handling events generated by others
agents5/29/2017 9
Second category focuses on
nonsocial or general processing.
According to this theory;-
Autistic behaviors results in
part from deficits in working,
memory, planning, inhibition
and other form of executive
functions
5/29/2017 10
SYMPTOMS
 Social difficulties;-
It is first sign of Autism
Lack of social smile with in 2nd or
3rd month of life of infant
Child don’t share their enjoyment
with others
Lack of social communication
Fail to develop typical friendships
Seem unaware of the feeling of
people5/29/2017 11
 Communication difficulties;-
Child have difficulties with
communication including both geoture
and speech
In some cases child don’t speak atoll.
When they are able to speak they may
repeat back exactly what is said to
them(echolalia)
Sometimes quote whole conversation
or dialog from a movie
5/29/2017 12
 Unusual behaviors;-
Insist on doing things exactly the
same way or on following the same
routine from day to day.
Become very upset in response to a
minor change
Repeat body movement such as
spinning, rocking or flapping hands
5/29/2017 13
When upset or excited they may
also harm themselves by skin biting
or head banging
Repetitively stacking or lining up
objects is a behavior occasionally
associated with individuals with
autism
5/29/2017 14
Associated symptoms;-
Belly pain, constipation or
diarrhea are frequently reported
 Increase in allergies and in
problem with immune system
Sensory sensitivity is quite
common especially to some
texture, sounds or smells
5/29/2017 15
Mental Retardation and Savant Skills;-
Demonstrate a particular skill,
such as memorizing phone
number, drawing landscapes
 Have wide variation in their
intellectual abilities
5/29/2017 16
CAUSES
Studies indicates that Autism is often associated
with abnormalities in functioning of brain and
disorder may have a genetic basis
 Genetic Disorder;-
Mutation in MECP2 gene on the X
chromosome(only in girl)
Variation in FMR1 gene on the X
chromosome(only in boy)
Defect in cholesterol pathway leads to
small head, upturned nose and undersized
lower jaw5/29/2017 17
Risk is doubled in children who inherit
a common variation of the MET gene
Brain Abnormalities;-
Increased level of serotonin
Decrease in the size of particular brain
region
Defects in the mirror neuron system
Infections and drugs;-
Children born to mothers who were
infected with certain illness or took
particular drug during pregnancy5/29/2017 18
5/29/2017 19
TREATMENT
No known cure for Autism
Use of individualized education,
communication tools, behavioral
management and medication
Parents, teachers and therapist need to work
together to help a child gain new skill and
abilities
When a child is diagnosed with autism, the
normal opinion is that the child will end up
spending a lonely life without being able to
achieve anything in life. However, this notion
is not true
5/29/2017 20
Therapy and training approaches;-
Picture schedule of time-limited task
A controversial aspect is the use of electric
shock to deter self-destructive behavior in
extreme cases
Floor system(frequent play sessions with a
parent to connect therapy goals activities that a
child finds exciting or fun)
5/29/2017 21
MEDICATION
Medication is not a primary treatment for autism
itself but can be helpful for related symptoms.
 Risperidone (Risperdal) is the first medication to
receive FDA approval in treatment of the
disordertreatment had significant aggression toward
themselves or others or episodes of extreme anger or
frustration.
 A group of medications called the serotonin reuptake
inhibitors have been used successfully to treat
compulsive behaviors in autism
5/29/2017 22
Serotonin include;-
fluoxetine (Prozac)
fluvoxamine (Luvox)
escitalopram (Lexapro)
No medication has been shown to have
significant effects on the social or
communication difficulties seen in autism
5/29/2017 23
DIAGNOSING AUTISM AND
RELATED DISORDERS
 Autistic children not show all symptoms of
disorder and hence need to get a clear
diagnosis and T/T plan by psychologist or
physician
 Two main diagnosis are Asperser's syndrome
and Perasive development disorder not
otherwise specified
 Two diagnoses, Rett syndrome and childhood
disintegrative disorder, are much rarer and
have a worse prognosis.
5/29/2017 24
1. Asperger’s Syndrome;-
 Lacks delay in cognitive development and
language or no clinically significant delay in
language or developmental age appropriate
skills
 Autism and Asperger’s syndrome are often
difficult to separate
 Children diagnosed with Asperger’s
syndrome often use unusual words and may
sound old-fashioned
5/29/2017 25
2. Perasive developmental disorder not otherwise
specified(PDD-NOS);-
 Children with this diagnosis can be very different
from one another
 Additionally, it is often difficult to separate
children who have PDD-NOS from children who
have speech or language problems that result in
difficulty forming relationships
 The particular areas of difficulty should be used
to shape the goals for each individual child, both
at home and at school.
5/29/2017 26
EDUCATION OF AUTISTIC
CHILDREN
Variable
Some children need self-contained
classroom with special education classes
No single approach will be correct for every
child with autism
Federal Law obligates public school to
assess each child’s individual needs
5/29/2017 27
Life of Adults with Autism
Some people are able to live and work
independently and pursued professional
carriers like Veterinary medicine,
mathematics etc
Some people have extremely unbelievable
memory capacity
 Some adults with severe autism requires
social support like either within a family
or in a group home or other residential
placement
5/29/2017 28
CONTROVERSIES
 Autism is a devastating disorder whose cause
remains poorly understood
 The fear that vaccines somehow lead to autism
i.e. persistent infection from the measles-
mumps-rubella vaccine
 Others fear that exposure to heavy metals such
as mercury and cadmium could lead to autism
 The frequent occurrence of gastrointestinal
symptoms in autism leads some to advocate for
various diets that remove wheat products, dairy
products, or even all carbohydrates5/29/2017 29
Famous people with unspecified
forms of autism
 The following people have been diagnosed as
being somewhere on the autistic spectrum but
the specific classification is unknown;-
One of the most famous people in
the world of science was Albert
Einstein. He was brilliant. Today,
there is some speculation over him
suffering from autism. However,
this cannot be proven. These
speculations are based on how he
behaved.5/29/2017 30
Michael Moon, adopted son of author
Elizabeth Moon
Robert Gagno, actor from Vancouver,
Christopher Knowles, American poet
Jasmine O'Neill, author of Through the Eyes of
Aliens
Richard Borcherds, mathematician specializing
in group theory and Lie algebras
Stephen Wiltshire, British architectural artist
Tony DeBlois, blind American musician
5/29/2017 31
REFERENCES
 Microsoft ® Encarta ® 2009. © 1993-2008 Microsoft
Corporation. All rights reserved
5/29/2017 32
THANKS A LOT FOR
YOUR KIND
ATTENTION!!!!!!!!!!!!
5/29/2017 33

Autism

  • 1.
  • 2.
    CONTENTIntroduction Prevalence Symptoms Social difficulties Communication difficulties Unusualbehaviors Associated symptoms Causes Genetic disorder Brain abnormalities Infections and drugs5/29/2017 2
  • 3.
     Treatment Therapy andtraining approaches Medications  Diagnosing Autism and related disorders Asperger’s Syndrome Perasive development disorder not otherwise specified  Education of children with Autism  Life of adults with Autism  Controversies  Famous people with unspecified forms of autism 5/29/2017 3
  • 4.
    5/29/2017 4 Disorder thataffects the social, emotional and behavioral development of children Marked by serious difficulties in interacting and communicating with other people American Psychiatrist Leo Kanner first described this disorder in 1943. It may be related to abnormal response to sensory input
  • 5.
    Autism is atleast 4 times more common in boys than in girls Autism comes from Greek word Auto; “self” means an abnormal withdrawal from the world outside oneself Causes of Autism remain a major area of research and controversy  There is no cure for Autism but some T/T and therapies can lessen the symptoms 5/29/2017 5
  • 6.
    PREVALENCE The number ofchildren diagnosed with Autism has increased since the 1990s Most recent estimates suggest that Autism occurs in approximately 1 in 500 children and that 1 in 150 children may be on “Autism spectrum” Girls with Autism, however tend to show more sever symptoms and mental impairment 5/29/2017 6
  • 7.
    MECHANISM How Autism occursis not well understood. It’s mechanism is divied into two main areas;- 1) Pathophysiology 2) Neurophysiology  Pathophysiology;-  Linkes the Brain Structure and process associated with Autism 5/29/2017 7
  • 8.
  • 9.
     Neurophysiology;-  Twomajor categories of cognitive theories have been proposed about the links between autistic brains and behavior The first category focuses on deficits in social cognitive. According to this theory;- Autistic child can develop internal rules of operation to handle events inside the brains- but are less effective at empathizing by handling events generated by others agents5/29/2017 9
  • 10.
    Second category focuseson nonsocial or general processing. According to this theory;- Autistic behaviors results in part from deficits in working, memory, planning, inhibition and other form of executive functions 5/29/2017 10
  • 11.
    SYMPTOMS  Social difficulties;- Itis first sign of Autism Lack of social smile with in 2nd or 3rd month of life of infant Child don’t share their enjoyment with others Lack of social communication Fail to develop typical friendships Seem unaware of the feeling of people5/29/2017 11
  • 12.
     Communication difficulties;- Childhave difficulties with communication including both geoture and speech In some cases child don’t speak atoll. When they are able to speak they may repeat back exactly what is said to them(echolalia) Sometimes quote whole conversation or dialog from a movie 5/29/2017 12
  • 13.
     Unusual behaviors;- Insiston doing things exactly the same way or on following the same routine from day to day. Become very upset in response to a minor change Repeat body movement such as spinning, rocking or flapping hands 5/29/2017 13
  • 14.
    When upset orexcited they may also harm themselves by skin biting or head banging Repetitively stacking or lining up objects is a behavior occasionally associated with individuals with autism 5/29/2017 14
  • 15.
    Associated symptoms;- Belly pain,constipation or diarrhea are frequently reported  Increase in allergies and in problem with immune system Sensory sensitivity is quite common especially to some texture, sounds or smells 5/29/2017 15
  • 16.
    Mental Retardation andSavant Skills;- Demonstrate a particular skill, such as memorizing phone number, drawing landscapes  Have wide variation in their intellectual abilities 5/29/2017 16
  • 17.
    CAUSES Studies indicates thatAutism is often associated with abnormalities in functioning of brain and disorder may have a genetic basis  Genetic Disorder;- Mutation in MECP2 gene on the X chromosome(only in girl) Variation in FMR1 gene on the X chromosome(only in boy) Defect in cholesterol pathway leads to small head, upturned nose and undersized lower jaw5/29/2017 17
  • 18.
    Risk is doubledin children who inherit a common variation of the MET gene Brain Abnormalities;- Increased level of serotonin Decrease in the size of particular brain region Defects in the mirror neuron system Infections and drugs;- Children born to mothers who were infected with certain illness or took particular drug during pregnancy5/29/2017 18
  • 19.
  • 20.
    TREATMENT No known curefor Autism Use of individualized education, communication tools, behavioral management and medication Parents, teachers and therapist need to work together to help a child gain new skill and abilities When a child is diagnosed with autism, the normal opinion is that the child will end up spending a lonely life without being able to achieve anything in life. However, this notion is not true 5/29/2017 20
  • 21.
    Therapy and trainingapproaches;- Picture schedule of time-limited task A controversial aspect is the use of electric shock to deter self-destructive behavior in extreme cases Floor system(frequent play sessions with a parent to connect therapy goals activities that a child finds exciting or fun) 5/29/2017 21
  • 22.
    MEDICATION Medication is nota primary treatment for autism itself but can be helpful for related symptoms.  Risperidone (Risperdal) is the first medication to receive FDA approval in treatment of the disordertreatment had significant aggression toward themselves or others or episodes of extreme anger or frustration.  A group of medications called the serotonin reuptake inhibitors have been used successfully to treat compulsive behaviors in autism 5/29/2017 22
  • 23.
    Serotonin include;- fluoxetine (Prozac) fluvoxamine(Luvox) escitalopram (Lexapro) No medication has been shown to have significant effects on the social or communication difficulties seen in autism 5/29/2017 23
  • 24.
    DIAGNOSING AUTISM AND RELATEDDISORDERS  Autistic children not show all symptoms of disorder and hence need to get a clear diagnosis and T/T plan by psychologist or physician  Two main diagnosis are Asperser's syndrome and Perasive development disorder not otherwise specified  Two diagnoses, Rett syndrome and childhood disintegrative disorder, are much rarer and have a worse prognosis. 5/29/2017 24
  • 25.
    1. Asperger’s Syndrome;- Lacks delay in cognitive development and language or no clinically significant delay in language or developmental age appropriate skills  Autism and Asperger’s syndrome are often difficult to separate  Children diagnosed with Asperger’s syndrome often use unusual words and may sound old-fashioned 5/29/2017 25
  • 26.
    2. Perasive developmentaldisorder not otherwise specified(PDD-NOS);-  Children with this diagnosis can be very different from one another  Additionally, it is often difficult to separate children who have PDD-NOS from children who have speech or language problems that result in difficulty forming relationships  The particular areas of difficulty should be used to shape the goals for each individual child, both at home and at school. 5/29/2017 26
  • 27.
    EDUCATION OF AUTISTIC CHILDREN Variable Somechildren need self-contained classroom with special education classes No single approach will be correct for every child with autism Federal Law obligates public school to assess each child’s individual needs 5/29/2017 27
  • 28.
    Life of Adultswith Autism Some people are able to live and work independently and pursued professional carriers like Veterinary medicine, mathematics etc Some people have extremely unbelievable memory capacity  Some adults with severe autism requires social support like either within a family or in a group home or other residential placement 5/29/2017 28
  • 29.
    CONTROVERSIES  Autism isa devastating disorder whose cause remains poorly understood  The fear that vaccines somehow lead to autism i.e. persistent infection from the measles- mumps-rubella vaccine  Others fear that exposure to heavy metals such as mercury and cadmium could lead to autism  The frequent occurrence of gastrointestinal symptoms in autism leads some to advocate for various diets that remove wheat products, dairy products, or even all carbohydrates5/29/2017 29
  • 30.
    Famous people withunspecified forms of autism  The following people have been diagnosed as being somewhere on the autistic spectrum but the specific classification is unknown;- One of the most famous people in the world of science was Albert Einstein. He was brilliant. Today, there is some speculation over him suffering from autism. However, this cannot be proven. These speculations are based on how he behaved.5/29/2017 30
  • 31.
    Michael Moon, adoptedson of author Elizabeth Moon Robert Gagno, actor from Vancouver, Christopher Knowles, American poet Jasmine O'Neill, author of Through the Eyes of Aliens Richard Borcherds, mathematician specializing in group theory and Lie algebras Stephen Wiltshire, British architectural artist Tony DeBlois, blind American musician 5/29/2017 31
  • 32.
    REFERENCES  Microsoft ®Encarta ® 2009. © 1993-2008 Microsoft Corporation. All rights reserved 5/29/2017 32
  • 33.
    THANKS A LOTFOR YOUR KIND ATTENTION!!!!!!!!!!!! 5/29/2017 33