Apcalis Oral Jelly is an oral medication used to treat erectile dysfunction in men. It contains tadalafil as the active ingredient and works by inhibiting the PDE5 enzyme to increase blood flow to the penis and allow an erection to occur with sexual stimulation. Apcalis Oral Jelly should be taken 15-30 minutes before sexual activity and can provide effects that last up to 48 hours. Common side effects include headaches, diarrhea, and muscle pain. It should not be used with nitrate medications or if the user has certain eye or heart conditions.