The document discusses alcohol withdrawal and alcoholic hepatitis. It notes that over 300,000 people in the UK have alcohol-related problems. Symptoms of alcohol withdrawal can begin within 12 hours and include agitation, nausea, and sweating. Delirium tremens can occur within 48 hours and is characterized by disorientation, agitation, and hallucinations. Treatment for alcohol withdrawal and hepatitis includes vitamins, fluids, antibiotics if needed, and benzodiazepines. Corticosteroids have shown benefits for severe alcoholic hepatitis defined as a Maddrey score over 32, reducing mortality rates. A pilot study combining corticosteroids and infliximab showed improvements in outcomes.