Agriculture biotechnology uses scientific techniques to improve plants, animals, and microorganisms. It is based on understanding DNA sequences. Scientists have developed solutions using biotechnology to increase agriculture productivity and make crops resistant to insects and pests. Methods used in agriculture biotechnology include genetic engineering to alter the genetic makeup of plants and livestock, molecular markers to identify DNA sequences, and molecular diagnostics to more accurately diagnose crop and livestock diseases. Biotechnology has also derived vaccines for livestock and enabled tissue culture techniques to clone plants.