- Adenomatoid odontogenic tumor (AOT) is a rare, benign tumor that occurs mostly in the maxilla near unerupted teeth. - It affects females more than males on average around 18 years of age. Radiographically, it appears as a well-defined radiolucency that may have faint radiopacities from calcification. - Microscopically, AOT contains duct-like structures lined with epithelial cells and surrounded by stellate reticulum-like cells. Treatment involves conservative surgical excision due to its slow-growing but progressive nature.

1. ADENOMATOID
ODONTOGENIC
TUMOR
-DR. LANA MICHAEL

2. Also Known As
• Adenoameloblastoma
• Ameloblastic Adenomatoid
Tumor

3. INTRODUCTION
Considered To Be An Uncommon Tumor Occurs
Mostly In Association With An Unerupted
Maxillary Cuspid.
It Is A Benign (Hamartomatous),non Invasive
Lesion With Slow But Progressive Growth.

4. CLINICAL FEATURES
Age: mean Age Of These Pts Was Approximately 18yrs,with
A Range Of 5-53yrs
Sex Predilection: marked Predilection For Occurrence Of
The Tumor In Females Than In Males.
Site Of Occurrence: greater In Maxilla Than In Mandible,
occurs More Frequently In The Anterior Part Of The Jaws With
76% Developing Anterior To The Cuspidin The Maxilla And
Mandible.
Size:1.5-3.0cm

6. RADIOGRAPHIC FEATURES
• On Radiographs It Usually Appears As A Well
Defined Radiolucency but Some Cases
Calcification Within The Tumor May Produce
faint Radiopacities
• The Lesion Is Often Associated With An
Unerupted Tooth And May Stimulate A
Dentigerous Cyst.

8. HISTOLOGIC FEATURES
• Macroscopic Features: central Aot’s
Macroscopically Appears As A Soft, roughly
Spherical Mass With A Distinct Fibrous Capsule.
• Microscopic Features: the Most Distinctive
Microscopic Feature Of Aot Is Varying Numbers Of
Duct Like Structures With Lumina Of Varying Size
That Are Lined By A Single Layer Of Cuboidal To
Columnar Epithelial Cells That Have Nuclei That
Frequently Are Polarized Away From The Lumen.
These Duct Like Or Microcyst Lumina Frequently
Are Lined By An Eosinophilic Rim Of Varying
Thickness (Hyaline Ring).

9. • The Stellate Reticulum Like Spindle Cells, and
Occasionally Round Or Polygonal Epithelial Cells
Dominate The Tissue Between The Cell Rich
Nodules. Small Amounts Of Eosinophilic
Material Or Calcifications Also May Be Present
Between These Cells.

11. TREATMENT
THE MAJORITY OF TUMORS OF THIS VARIETY HAVE
BEEN TREATED BY CONSERVATIVE SURGICAL
EXCISION

12. THANK
YOU