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Abnormalities
of
Placenta and Cord
GUIDE: LT COL AJITHA T Y SPEAKER: MAJ B ROSHNI
I YEAR MSC NURSING
COLLEGE OF NURSING
CH(EC) KOLKATA
What is Placenta?
 It is an organ which is responsible for nourishing and
protecting a fetus during pregnancy
Placental abnormalities-
 it refers to marked variations including anatomical,
physiological and abnormal implantations of
placenta that may lead to serious placental maternal
fetal effects
Functions of placenta
 Respiratory
 Excretory
 Nutritive
 Endocrine functions
 Barrier function
 Immunological function
Abnormalities of placenta
 Classified according to
Size and shape
Placental implantation
Circulatory disturbances
Placental tumors
Abnormalities of shape and size
A. Placenta succenturiate
Placenta succenturiate
 one or more small lobes of placenta, size of cotyledon may be
placed at varying distances from the placental margin
 Incidence- 3%
 Clinical significance-
 If the succenturiate lobe is retained following delivery of
placenta it may lead to
 PPH
 Subinvolution
 Uterine sepsis
 Polyp formation
 Placenta Spuria-
 Placenta succenturiate in which
there is absence of communicating
blood vessels it is called placenta
spuria
Placenta extrachorialis
It is of two types:-
 Circumvallate placenta
 Placenta marginata
Circumvallate placenta
 The fetal surface is divided into a
central depressed zone surrounded by
a thickened white ring which is usually
complete.
 Vessels radiate from the cord
insertion as far as the ring and
then disappear from view.
 The peripheral zone outside the ring
is thicker and the edge is elevated
and rounded.
 Incidence- 0.5-18%
Placenta Marginata
 A thin fibrous ring is present at
the margin of the chorionic
plate where the fetal vessels
appear to terminate.
Clinical significance
There are increased chance of
 Antepartum hemorrhage
 FGR baby
 Abortion
 Preterm delivery
 Retained placenta or membranes
Placenta Membranecea
 Placenta is unduly large and thin
 The placenta not only develops
from the chorion frondosum but
also from the chorion laeve so
that the whole of the ovum is
practically covered by the
placenta
Clinical significance
 Encroachment of some part over the lower
segment.
 Imperfect separation in the third stage.
 Chance of retained placenta is more and
manual removal becomes difficult.
Placenta bilobate/Bipartite
 Placenta may develop as separate and
nearly equally sized discs
 Umbilical cord is attached into a
connecting chorionic bridge or
intervening membranes
 Clinical significance
 Same as placenta Succenturiate
Placenta Fenestrata
 This is due to missing of
central portion of the
placental disk
 Clinical Significance
 It may be mistaken as if the
central cotyledon is retained
inside uterus
Abnormalities of placental
implantation
 Mal adherent placenta
 Mal positioned placenta
Placenta accrete Syndromes
These are abnormally implanted
invasive or adhered placenta
 Placenta accreta - indicates villi are
attached in myometrium
 Placenta increta - indicates villi
actually invade the myometrium
 Placenta percreta- villi that
penetrate through the myometrium
and to or through serosa
Clinical significance
 They are leading cause of intractable postpartum
haemorrhage and emergency peripartum
hysterectomy
ABNORMALITIES RELATED TO
CIRCULATION
Abnormalities R/T circulation
A. Subchorionic fibrin deposition- These are caused
by slowing of maternal blood flow within the
intervillus space
B. Perivillous fibrin deposition-maternal flow stasis
around an individual villus results in perivillous
fibrin deposition
C. Maternal floor infarction
D. Intervillous thrombus
E. Infarction
Clinical significance
 These are common lesions in mature placentas and
are benign in limited numbers
 If they are numerous placental insufficiency can
develop
Hematoma
 Types
 Retroplacental hematoma
 Marginal hematoma
 Subchorial thrombosis
 Subamnionic hematoma
Placental calcification
 Calcium salts may be deposited throughout the placenta, but
are most common on basal plate
 Calcification arises within advancing gestation and is
associated with nullipariy, smoking, Increase in maternal
serum calcium levels
ABNORMALITIES OF MEMBRANES
Abnormality of Membranes
Meconium staining
chorioamnionitis
ABNORMALITIES OF UMBILICAL CORD
Abnormalities of Umbilical Cord
 Short cord - Less than 20cm or commonly relative
due to entanglement of the cord round any fetal part.
 In exceptional circumstances, the cord may be absent and
the placenta may be attached to the liver as in
exomphalus.(acordia)
Clinical significance
 Prevent descent of the presenting part specially during labour
 Separation of normally situated placenta
 Favour malpresentation
 Acute inversion
 Fetal growth restriction
 Intrapartum distress
 Failure of external version
 Two fold risk of fetal death
Long cord -
 If length is more than 100cm
 Clinical significance
 cord prolapse
 cord entanglement round the neck or the body
 True knot False knots
Single umbilical artery
 It is more common in twins and in babies born of
diabetic mothers or in polyhydramnios
Clinical significance
 It is frequently associated with congenital
malformation of the fetus (10-20%).
 Renal and genital anomalies, Trisomy 18 are
common.
 There is increased chance of
 Abortion, Prematurity, FGR
 Perinatal mortality
Cord insertion
 Battledore placenta-
The cord is attachedto the margin of the
placenta.
If associated with low implantation of the
placenta, there is chance of cord compression in
vaginal delivery leading to fetal anoxia or even
death; otherwise, it has got little clinical
significance.
Battledore placenta-
Velamentous placenta
 The umbilical vessels spread within the
membranes at a distance from the placental
margin, which they reach surrounded only by a fold
of amnion.
 Although their incidence is approximately 1
percent, velamentous insertion develops in
more commonly with placenta previa and
multifetal gestations.
Vasa previa
 If the leash of blood vessels happen to
traverse through the membranes overlying the
internal os, infront of the presenting part, the
condition is called vasa praevia.
Cord abnormalities of impending
blood flow
Knots
True knots
False knots
 Loops
 Umbilical cord stricture
 False Knots
False knots appear as knobs protruding from the cord surface and are
focal redundancies of a vessel or Wharton jelly, with no clinical significance.
True knots
 Active fetal movements create cord knotting.
 Incidence : approximately 1%, and these are
more common in monoamnionic twins.
 The risk of stillbirth is increased five- to
tenfold.
Loops
 The cord frequentlybecomes coiled around portions of the
fetus.
 Those looped around theneck aretermed a nuchal
cord
 several large studies have reported one loop of nuchal
cord in 20 to 34 percent of deliveries; two loops in 2.5
to 5 percent; and three loops in 0.2 to 0.5 percent
Nuchal cord
Clinical significance
 As labor progresses, contractions may
compress the cord vessels and create fetal
heart rate decelerations that persist until
the contraction ceases.
Umbilical stricture
Umbilical stricture
 This is a focal narrowing of the cord diameter that typically
develops in the area of fetal umbilical insertion .
 Absence of Wharton Jelly and stenosis or obliteration of cord
vessels at the narrow segment are characteristic pathological
feature
 Most foetuses are stillborn
Hematomas
Hematomas
Associated with short cords,trauma and entanglement
Results from varix rupture usually of the umbilical vein
May also be caused by umbilical vessel venipuncture
Cysts
Cysts
 True cysts are epithelium-lined remnants of
the allantois and may co-exist with a persistently
patent urachus.
 In contrast,the more common pseudocysts
form from local degeneration of Wharton jelly.
Clinical significance
 Single umbilical cord cysts found in the first
trimester tend to resolve completely, whereas
multiple cysts may portend miscarriage or
aneuploidy.
 Moreover, pseudocysts persisting beyond this can
be associated with structural and
chromosomal anomalies defects, especially
trisomy 18 and 13.
Summary
Queries?
Assignment
 Identify the abnormalities of placenta in following pictures-
Q.2-Umbilical cord comprises how many arteries &
veins?
a) 2 arteries & 2 veins
b) 2 arteries & 1 vein
c) 1 artery & 2 veins
d) 1 artery & 1 vein
Q.3 what is clinical significance of battledore
placenta?
 Postpartum haemorrhage
 Cord compression
 Retained placenta
 None of the above
Q.4 what is chorioamnionitis?
 Abnormality of chorion
 Abnormality of placental membranes
 Inflammation of placental membranes
 Inflammation of placenta

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abnormalities of placenta.pptx

  • 1.
  • 2. Abnormalities of Placenta and Cord GUIDE: LT COL AJITHA T Y SPEAKER: MAJ B ROSHNI I YEAR MSC NURSING COLLEGE OF NURSING CH(EC) KOLKATA
  • 3. What is Placenta?  It is an organ which is responsible for nourishing and protecting a fetus during pregnancy Placental abnormalities-  it refers to marked variations including anatomical, physiological and abnormal implantations of placenta that may lead to serious placental maternal fetal effects
  • 4. Functions of placenta  Respiratory  Excretory  Nutritive  Endocrine functions  Barrier function  Immunological function
  • 5. Abnormalities of placenta  Classified according to Size and shape Placental implantation Circulatory disturbances Placental tumors
  • 6. Abnormalities of shape and size A. Placenta succenturiate
  • 7.
  • 8. Placenta succenturiate  one or more small lobes of placenta, size of cotyledon may be placed at varying distances from the placental margin  Incidence- 3%  Clinical significance-  If the succenturiate lobe is retained following delivery of placenta it may lead to  PPH  Subinvolution  Uterine sepsis  Polyp formation
  • 9.  Placenta Spuria-  Placenta succenturiate in which there is absence of communicating blood vessels it is called placenta spuria
  • 10. Placenta extrachorialis It is of two types:-  Circumvallate placenta  Placenta marginata
  • 11. Circumvallate placenta  The fetal surface is divided into a central depressed zone surrounded by a thickened white ring which is usually complete.  Vessels radiate from the cord insertion as far as the ring and then disappear from view.  The peripheral zone outside the ring is thicker and the edge is elevated and rounded.  Incidence- 0.5-18%
  • 12. Placenta Marginata  A thin fibrous ring is present at the margin of the chorionic plate where the fetal vessels appear to terminate.
  • 13. Clinical significance There are increased chance of  Antepartum hemorrhage  FGR baby  Abortion  Preterm delivery  Retained placenta or membranes
  • 14. Placenta Membranecea  Placenta is unduly large and thin  The placenta not only develops from the chorion frondosum but also from the chorion laeve so that the whole of the ovum is practically covered by the placenta
  • 15.
  • 16. Clinical significance  Encroachment of some part over the lower segment.  Imperfect separation in the third stage.  Chance of retained placenta is more and manual removal becomes difficult.
  • 17. Placenta bilobate/Bipartite  Placenta may develop as separate and nearly equally sized discs  Umbilical cord is attached into a connecting chorionic bridge or intervening membranes  Clinical significance  Same as placenta Succenturiate
  • 18. Placenta Fenestrata  This is due to missing of central portion of the placental disk  Clinical Significance  It may be mistaken as if the central cotyledon is retained inside uterus
  • 19. Abnormalities of placental implantation  Mal adherent placenta  Mal positioned placenta
  • 20. Placenta accrete Syndromes These are abnormally implanted invasive or adhered placenta  Placenta accreta - indicates villi are attached in myometrium  Placenta increta - indicates villi actually invade the myometrium  Placenta percreta- villi that penetrate through the myometrium and to or through serosa
  • 21. Clinical significance  They are leading cause of intractable postpartum haemorrhage and emergency peripartum hysterectomy
  • 23. Abnormalities R/T circulation A. Subchorionic fibrin deposition- These are caused by slowing of maternal blood flow within the intervillus space B. Perivillous fibrin deposition-maternal flow stasis around an individual villus results in perivillous fibrin deposition C. Maternal floor infarction D. Intervillous thrombus E. Infarction
  • 24. Clinical significance  These are common lesions in mature placentas and are benign in limited numbers  If they are numerous placental insufficiency can develop
  • 25. Hematoma  Types  Retroplacental hematoma  Marginal hematoma  Subchorial thrombosis  Subamnionic hematoma
  • 26.
  • 27. Placental calcification  Calcium salts may be deposited throughout the placenta, but are most common on basal plate  Calcification arises within advancing gestation and is associated with nullipariy, smoking, Increase in maternal serum calcium levels
  • 29. Abnormality of Membranes Meconium staining chorioamnionitis
  • 31. Abnormalities of Umbilical Cord  Short cord - Less than 20cm or commonly relative due to entanglement of the cord round any fetal part.  In exceptional circumstances, the cord may be absent and the placenta may be attached to the liver as in exomphalus.(acordia)
  • 32.
  • 33. Clinical significance  Prevent descent of the presenting part specially during labour  Separation of normally situated placenta  Favour malpresentation  Acute inversion  Fetal growth restriction  Intrapartum distress  Failure of external version  Two fold risk of fetal death
  • 34. Long cord -  If length is more than 100cm  Clinical significance  cord prolapse  cord entanglement round the neck or the body  True knot False knots
  • 35.
  • 36. Single umbilical artery  It is more common in twins and in babies born of diabetic mothers or in polyhydramnios
  • 37. Clinical significance  It is frequently associated with congenital malformation of the fetus (10-20%).  Renal and genital anomalies, Trisomy 18 are common.  There is increased chance of  Abortion, Prematurity, FGR  Perinatal mortality
  • 38. Cord insertion  Battledore placenta- The cord is attachedto the margin of the placenta. If associated with low implantation of the placenta, there is chance of cord compression in vaginal delivery leading to fetal anoxia or even death; otherwise, it has got little clinical significance.
  • 40. Velamentous placenta  The umbilical vessels spread within the membranes at a distance from the placental margin, which they reach surrounded only by a fold of amnion.  Although their incidence is approximately 1 percent, velamentous insertion develops in more commonly with placenta previa and multifetal gestations.
  • 41.
  • 42. Vasa previa  If the leash of blood vessels happen to traverse through the membranes overlying the internal os, infront of the presenting part, the condition is called vasa praevia.
  • 43. Cord abnormalities of impending blood flow Knots True knots False knots  Loops  Umbilical cord stricture
  • 44.  False Knots False knots appear as knobs protruding from the cord surface and are focal redundancies of a vessel or Wharton jelly, with no clinical significance.
  • 45. True knots  Active fetal movements create cord knotting.  Incidence : approximately 1%, and these are more common in monoamnionic twins.  The risk of stillbirth is increased five- to tenfold.
  • 46. Loops  The cord frequentlybecomes coiled around portions of the fetus.  Those looped around theneck aretermed a nuchal cord  several large studies have reported one loop of nuchal cord in 20 to 34 percent of deliveries; two loops in 2.5 to 5 percent; and three loops in 0.2 to 0.5 percent
  • 48. Clinical significance  As labor progresses, contractions may compress the cord vessels and create fetal heart rate decelerations that persist until the contraction ceases.
  • 50. Umbilical stricture  This is a focal narrowing of the cord diameter that typically develops in the area of fetal umbilical insertion .  Absence of Wharton Jelly and stenosis or obliteration of cord vessels at the narrow segment are characteristic pathological feature  Most foetuses are stillborn
  • 52. Hematomas Associated with short cords,trauma and entanglement Results from varix rupture usually of the umbilical vein May also be caused by umbilical vessel venipuncture
  • 53. Cysts
  • 54. Cysts  True cysts are epithelium-lined remnants of the allantois and may co-exist with a persistently patent urachus.  In contrast,the more common pseudocysts form from local degeneration of Wharton jelly.
  • 55. Clinical significance  Single umbilical cord cysts found in the first trimester tend to resolve completely, whereas multiple cysts may portend miscarriage or aneuploidy.  Moreover, pseudocysts persisting beyond this can be associated with structural and chromosomal anomalies defects, especially trisomy 18 and 13.
  • 58. Assignment  Identify the abnormalities of placenta in following pictures-
  • 59.
  • 60.
  • 61.
  • 62.
  • 63.
  • 64. Q.2-Umbilical cord comprises how many arteries & veins? a) 2 arteries & 2 veins b) 2 arteries & 1 vein c) 1 artery & 2 veins d) 1 artery & 1 vein
  • 65. Q.3 what is clinical significance of battledore placenta?  Postpartum haemorrhage  Cord compression  Retained placenta  None of the above
  • 66. Q.4 what is chorioamnionitis?  Abnormality of chorion  Abnormality of placental membranes  Inflammation of placental membranes  Inflammation of placenta

Editor's Notes

  1. A leash of vessels connecting the main to the small lobe traverse through the membranes.the accessory lobe is developed from the activated villi on the chorionic laeve
  2. Treatment –whenever the diagnosis of missing lobe is made,exploration of the uterus and removal of the lobe under general anesthesia is to be done
  3. Placenta extrachorialis is a morphological abnormality of the placenta, defined as "a condition in which the transition from a membranous to villous chorion does not occur at the placental edge but at some variable distance within the circumference of the placenta" (1). Therefore there is placental tissue beyond the limits of the chorionic plate. The basal plate of villous tissue (located on the maternal side of the placenta) extends laterally beyond the chorionic plate from which the villi originate (located on the fetal side). The chorionic plate is thus smaller than the basal plate (1). This arrangement leaves some placental tissue outside the limits of the chorionic plate, hence the name placenta extrachorialis
  4. The placenta of such type is due to the smaller chorionic plate than the basal plate The chorionic plate does not extend to the placental margin. Increased risk of vaginal bleeding at the beginning of first trimester,risk of PPROM,preterm deliveries,placental insufficiency,placental abruption If it is found antenatally ..this pregnancy is classified as high risk pregnancy
  5. These abnormalities are serious variations in which trophoblastic tissues invade the myometrium to varying depths. Mal adherent placenta