We think it is important to think ahead and to consider what issues the medical industry will be facing in the future.
As we near 2015 we’ve decided to use this as a half-way point. In this infographic we’ve reflected on significant global changes over the last 15 years and looked at the forecasts for the next 15. The result is a glimpse of what challenges healthcare will face in 2030. Can we do anything today to change the future? Or if we accept this vision of the future what do we need to do now to best prepare?
OIP Device Design: Approaches to Creating Successful Products for Patient UseTeam Consulting Ltd
Ben Cox, Senior Consultant at Team Consulting, presented this at the World Congress of the International Society for Aerosols in Medicine in April 2013
ONdrugDelivery - The advantages of designing high-resistance swirl chambers f...Team Consulting Ltd
In this article, David Harris, Head of Respiratory Drug Delivery, Team Consulting, taps into a powerful combination of detailed anatomical and functional understanding of the human respiratory system, pulmonary drug delivery technology and formulation expertise, and mathematical modelling techniques, in order to put forward the case for high-resistance swirl chambers in dry-powder inhalers, and a rational strategy for optimising the design and thus maximising therapeutic efficacy.
We think it is important to think ahead and to consider what issues the medical industry will be facing in the future.
As we near 2015 we’ve decided to use this as a half-way point. In this infographic we’ve reflected on significant global changes over the last 15 years and looked at the forecasts for the next 15. The result is a glimpse of what challenges healthcare will face in 2030. Can we do anything today to change the future? Or if we accept this vision of the future what do we need to do now to best prepare?
OIP Device Design: Approaches to Creating Successful Products for Patient UseTeam Consulting Ltd
Ben Cox, Senior Consultant at Team Consulting, presented this at the World Congress of the International Society for Aerosols in Medicine in April 2013
ONdrugDelivery - The advantages of designing high-resistance swirl chambers f...Team Consulting Ltd
In this article, David Harris, Head of Respiratory Drug Delivery, Team Consulting, taps into a powerful combination of detailed anatomical and functional understanding of the human respiratory system, pulmonary drug delivery technology and formulation expertise, and mathematical modelling techniques, in order to put forward the case for high-resistance swirl chambers in dry-powder inhalers, and a rational strategy for optimising the design and thus maximising therapeutic efficacy.
Designing the Enterprise for Manufacturingsc0ttruss
Britain has a long history of manufacturing, and whilst the decline of the sector is well documented, applying the basic principles of traditional manufacturing to the “whitecollar” office environment is the new manufacturing. This talk will take you through the basic building patterns of manufacturing, looking at vendor selection/audits, the QA process, understanding of basic costings, discovering if the “products” are low volume, High mix, or low mix high volume and what the implications of design for manufacture would be in such an environment. Also, how to apply these basic patterns to the modern software driven “Office ” world. This is part one of a two part talk, the second one being “Preparing the Enterprise for Manufacturing”.
Everyday Lessons from Extraordinary Circumstances.
The business decisions we make often have unforeseen, far-reaching effects wholly unrelated to its original intent.
5
A Pragmatic Approach to
Lifecycle Analysis
Formal lifecycle analysis is not new; in fact, lifecycle analysis tools andtechniques have been around in various forms for decades. What is newis an urgent need to improve the tools and expand the use of lifecycle
analysis to a broader spectrum of products and services.
We’re going to use a pragmatic approach to lifecycle analysis that keeps
the focus on the main goals: understanding the overall impact and making
improvements. The truth is that you don’t always need to measure every-
thing; you don’t always need precise data; you don’t always need complete
information. You just need to know what to measure, when, and how—and
where to place your priorities.
To get started we’ll need a model of the product/service lifecycle that we
can use to organize our work. So, let’s take a closer look at the phases of a
typical lifecycle and the key considerations at each phase.
A Basic Lifecycle Model
Every product is different; every lifecycle has unique time frames and char-
acteristics. As a result, many different lifecycle models have been produced
over time. For this book, we use a basic three-stage model. We prefer this
model because it is straightforward and matches most people’s personal expe-
rience with the lifecycle stages of common products. The three stages of our
model are
• “Make,” which covers everything that happens before a product is
actually put into operation—including the materials and chemicals
45
that are used to create it, the processes involved in assembling and
manufacturing it, the packaging that encases it, and the supply chain
that distributes it
• “Use,” which includes the power the product consumes as it is
operated, the greenhouse gas (GHG) and other emissions it creates,
the water it uses, and the noise, light, and heat it generates during
operation
• “Renew,” which covers everything that happens after the product is
used, including the demanufacture or disassembly of the product,
reuse of key components, recycling, and take-back
At each stage of the lifecycle we focus on three primary aspects of the
environmental impact of a product or service:
• Energy and emissions, including the calculation of energy and
power, finding the cleanest source of energy for your product, using
energy efficiently, calculating GHG emissions and CO2 conversion,
and so on
• Chemicals, materials, and waste, including the legal and business
considerations of hazardous and toxic substances, packaging and doc-
umentation, waste disposal, recycling, take-back, and process-related
GHG emissions
• Water and other natural resources that are embodied in the product
or service, including social and business considerations of using
scarce or nonrenewable materials, calculating the water footprint, and
so forth
Additional Lifecycle Considerations
Our three-phase model is intentionally simplistic. So, before we discuss
each aspect of the lifecycle in more detail, we’d like to offer a few notes.
Hazard and Operability Study (HAZOP) | Gaurav Singh RajputGaurav Singh Rajput
Hazard and operability study | hazop | method of conduction | steps involved by gauravsinghrajput | gauravkrsrajput I Gaurav Singh Rajput I gauravsinghrajput I gauravkrsrajput
Designing the Enterprise for Manufacturingsc0ttruss
Britain has a long history of manufacturing, and whilst the decline of the sector is well documented, applying the basic principles of traditional manufacturing to the “whitecollar” office environment is the new manufacturing. This talk will take you through the basic building patterns of manufacturing, looking at vendor selection/audits, the QA process, understanding of basic costings, discovering if the “products” are low volume, High mix, or low mix high volume and what the implications of design for manufacture would be in such an environment. Also, how to apply these basic patterns to the modern software driven “Office ” world. This is part one of a two part talk, the second one being “Preparing the Enterprise for Manufacturing”.
Everyday Lessons from Extraordinary Circumstances.
The business decisions we make often have unforeseen, far-reaching effects wholly unrelated to its original intent.
5
A Pragmatic Approach to
Lifecycle Analysis
Formal lifecycle analysis is not new; in fact, lifecycle analysis tools andtechniques have been around in various forms for decades. What is newis an urgent need to improve the tools and expand the use of lifecycle
analysis to a broader spectrum of products and services.
We’re going to use a pragmatic approach to lifecycle analysis that keeps
the focus on the main goals: understanding the overall impact and making
improvements. The truth is that you don’t always need to measure every-
thing; you don’t always need precise data; you don’t always need complete
information. You just need to know what to measure, when, and how—and
where to place your priorities.
To get started we’ll need a model of the product/service lifecycle that we
can use to organize our work. So, let’s take a closer look at the phases of a
typical lifecycle and the key considerations at each phase.
A Basic Lifecycle Model
Every product is different; every lifecycle has unique time frames and char-
acteristics. As a result, many different lifecycle models have been produced
over time. For this book, we use a basic three-stage model. We prefer this
model because it is straightforward and matches most people’s personal expe-
rience with the lifecycle stages of common products. The three stages of our
model are
• “Make,” which covers everything that happens before a product is
actually put into operation—including the materials and chemicals
45
that are used to create it, the processes involved in assembling and
manufacturing it, the packaging that encases it, and the supply chain
that distributes it
• “Use,” which includes the power the product consumes as it is
operated, the greenhouse gas (GHG) and other emissions it creates,
the water it uses, and the noise, light, and heat it generates during
operation
• “Renew,” which covers everything that happens after the product is
used, including the demanufacture or disassembly of the product,
reuse of key components, recycling, and take-back
At each stage of the lifecycle we focus on three primary aspects of the
environmental impact of a product or service:
• Energy and emissions, including the calculation of energy and
power, finding the cleanest source of energy for your product, using
energy efficiently, calculating GHG emissions and CO2 conversion,
and so on
• Chemicals, materials, and waste, including the legal and business
considerations of hazardous and toxic substances, packaging and doc-
umentation, waste disposal, recycling, take-back, and process-related
GHG emissions
• Water and other natural resources that are embodied in the product
or service, including social and business considerations of using
scarce or nonrenewable materials, calculating the water footprint, and
so forth
Additional Lifecycle Considerations
Our three-phase model is intentionally simplistic. So, before we discuss
each aspect of the lifecycle in more detail, we’d like to offer a few notes.
Hazard and Operability Study (HAZOP) | Gaurav Singh RajputGaurav Singh Rajput
Hazard and operability study | hazop | method of conduction | steps involved by gauravsinghrajput | gauravkrsrajput I Gaurav Singh Rajput I gauravsinghrajput I gauravkrsrajput
The advantages of a connected device can be explored through the different categories of needs, by trialling a range of solutions and considering a framework of manageable steps.
Thinking Human by Julian Dixon, PMPS Inhalation Technology SupplementTeam Consulting Ltd
As medical device companies strive to make their products more user-friendly, it becomes clear that listening to the end user is an important part of the process. Through small-scale studies and human factor analysis, inhalers can be developed that are simple and easy to use.
In an issue of IPT (Innovations in Pharmaceutical Technology) magazine, Team Consulting's David Harris explores the benefits of dry powder inhalers for a range of new therapeutic areas, outside of traditional asthma and COPD treatments.
If you were to tell some people that one of the most frustrating aspects of the development of a drug delivery device would be the little clicks that it makes as part of its operation, they would probably think you had lost your sense of priority.
Device developers know this - whether human factors experts or industrial designers, mechanical engineers, or risk analysis teams - yet this aspect of device design, like many others, is frequently not given the attention it deserves. So why is a click so important?
Designing for battery-powered and battery-packed medical devices, EPD&T, Dec ...Team Consulting Ltd
Team's Jonathan Oakley writes about designing the 'graceful shutdown'. When power starts to run out in a medical device it is important to think about which parts of the system are affected and at what stage.
First published in EPD&T in December 2013 http://www.epdtonthenet.net/
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Elevating Tactical DDD Patterns Through Object CalisthenicsDorra BARTAGUIZ
After immersing yourself in the blue book and its red counterpart, attending DDD-focused conferences, and applying tactical patterns, you're left with a crucial question: How do I ensure my design is effective? Tactical patterns within Domain-Driven Design (DDD) serve as guiding principles for creating clear and manageable domain models. However, achieving success with these patterns requires additional guidance. Interestingly, we've observed that a set of constraints initially designed for training purposes remarkably aligns with effective pattern implementation, offering a more ‘mechanical’ approach. Let's explore together how Object Calisthenics can elevate the design of your tactical DDD patterns, offering concrete help for those venturing into DDD for the first time!
JMeter webinar - integration with InfluxDB and GrafanaRTTS
Watch this recorded webinar about real-time monitoring of application performance. See how to integrate Apache JMeter, the open-source leader in performance testing, with InfluxDB, the open-source time-series database, and Grafana, the open-source analytics and visualization application.
In this webinar, we will review the benefits of leveraging InfluxDB and Grafana when executing load tests and demonstrate how these tools are used to visualize performance metrics.
Length: 30 minutes
Session Overview
-------------------------------------------
During this webinar, we will cover the following topics while demonstrating the integrations of JMeter, InfluxDB and Grafana:
- What out-of-the-box solutions are available for real-time monitoring JMeter tests?
- What are the benefits of integrating InfluxDB and Grafana into the load testing stack?
- Which features are provided by Grafana?
- Demonstration of InfluxDB and Grafana using a practice web application
To view the webinar recording, go to:
https://www.rttsweb.com/jmeter-integration-webinar
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
This presentation was delivered at K8SUG Singapore. See https://feryn.eu/presentations/accelerate-your-kubernetes-clusters-with-varnish-caching-k8sug-singapore-28-2024 for more details.
Software Delivery At the Speed of AI: Inflectra Invests In AI-Powered QualityInflectra
In this insightful webinar, Inflectra explores how artificial intelligence (AI) is transforming software development and testing. Discover how AI-powered tools are revolutionizing every stage of the software development lifecycle (SDLC), from design and prototyping to testing, deployment, and monitoring.
Learn about:
• The Future of Testing: How AI is shifting testing towards verification, analysis, and higher-level skills, while reducing repetitive tasks.
• Test Automation: How AI-powered test case generation, optimization, and self-healing tests are making testing more efficient and effective.
• Visual Testing: Explore the emerging capabilities of AI in visual testing and how it's set to revolutionize UI verification.
• Inflectra's AI Solutions: See demonstrations of Inflectra's cutting-edge AI tools like the ChatGPT plugin and Azure Open AI platform, designed to streamline your testing process.
Whether you're a developer, tester, or QA professional, this webinar will give you valuable insights into how AI is shaping the future of software delivery.
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
1. Official SpOnSOr
emdt.co.uk
November/December 2011
The Magazine for Medical Product Design & Manufacturing
Extrusion
Technologies page 82
Inside Advice on
Medical Electronics
pages 24 and 80
When Is Software a
Medical Device?
page 21
Compamed Preview
page 53
What You Need to Know
about the RoHS Recast
page 42
Using Nitinol Sheet in
Medical Implants
page 28
2. design
A Fluid
Situation
Strategies for designing a reliable,
repeatable fluid handling system.
Philip Canner, Team Consulting Ltd,
Cambridge, UK
From dialysis machines and infusion phase. The article is based on the author’s much of the system as possible. Other
pumps to small handheld devices such experience of designing high-performance users—those handling point-of-care
as inhalers and pen injectors, reliable disposable fluid circuits, with flow rates in-vitro diagnostic devices, for example—
and repeatable fluid handling is a critical ranging from millilitres/hour to litres/ will expect to barely handle the fluid
process. The challenge with fluids, minute, but many of the underlying circuit at all. Above all, the project team
however, is that you almost never quite principles can be applied to the design must ensure that the product is safe
know what is going to happen until you process for all fluid handling devices. to use. Product performance, safety,
try it. An innocuous change to a fluid usability and risk management are of
circuit design, done for reasons that may Requirements capture paramount importance from the start of
have nothing to do with fluid handling, The first stage in product development is the project.
can result in an unexpected shift in fluid to define the requirements for the system. As a medical device, the fluid contact
behaviour. This can make designing Because of the challenges of ensuring that materials in the system probably will be
fluid handling devices and equipment fluid circuits do exactly what they should, required to meet certain standards such
a daunting task, and the potential for every time, it is important to verify that as USP Class VI and ISO 10993; in the
rework is huge. However, armed with the constraints have been defined fully. case of plastics, they may be required
some knowledge of the potential risks, Different users will have very different to be free of certain plasticisers such as
and where time can best be used or requirements, knowledge levels and DEHP. It is important that the material
saved, a plan can be put together that expectations, all of which will impact requirements and sterilisation process
gives the project the best possible chance the design, complexity and performance be determined early, because, as will be
Leigh Prather/Shutterstock.com
of success, both in terms of the final requirements of the system. For example, discussed later, the prototypes should be
product and the budget. perfusionists in a surgical team may made from the same materials as the final
The items outlined below are intended expect to spend time setting up a fluid device. Sterilisation often affects material
to give the project planner and team circuit and removing air bubbles from properties, and testing prototypes that
insight into what to watch out for in each it, and may want unfettered access to as are of the right material and have been
3. design
through the sterilisation process can and built to the same tolerances—and cannot be found, the alternative is the
help reduce development risk. If the will be tested with the correct fluids custom-made part. Before abandoning
design involves tubing that may be under realistic operating conditions. the off-the-shelf solution, however, it
stored for a period of time in a folded, This becomes increasingly important should be taken into consideration that
twisted or rolled state, this needs to be the smaller the scale at which you are the off-the-shelf component allows
taken into account. working, because the physics change as the team to get into the lab and test
systems shrink in size. concepts with the actual components
Conceptual design and proof-of- Therefore, it is helpful to ensure that will be in the final system—a lot of
principle that the conceptual design involves the regulatory work already may have
After the requirements for the product manufacturing processes that can be been done.
have been determined, it is time to prototyped, or to put it in reverse, When the concepts are being
generate design concepts. To ensure that the prototypes mimic as best they prepared for prototyping, it is important
that the team does not spend too much can the intended final production to know when not to use CAD.
time running down wrong tracks, plan techniques. If the manufacturer has Certainly for fluid circuits involving
on spending time in the lab as early not already been identified, then the tubing, connectors and various other
in the project as possible to test these conceptual design stage is the right time components in the line, it can be more
concepts with proof-of-principle rigs. to start thinking about manufacturing efficient to get into the lab with a
Altering fluids, contact materials, partners. By finding and talking to sketch, a few reels of tubing and all
temperatures, pressures, flow paths, manufacturers with experience in the components, and hang them off
surface finishes, sterilisation techniques the type of fluid circuit that is being scaffolding. In this way, a large number
and so forth can dramatically change designed, their insight and knowledge of concepts can be worked through, and
the system’s behaviour. This has a can be fed into the designs, saving time the learning curve can be ascended, very
significant impact on the approach and avoiding the worst-case scenario quickly.
that should be taken in the design and of designing a system unsuitable When testing prototypes in the lab,
prototyping of for volume the most important rule is to use the
such systems. production. The correct fluids. This may be the single
As helpful at As helpful at getting manufacturer most important factor in getting
getting fast insights also may have representative results. If the fluid circuit
as they may be, fast insights as they preferred is designed for handling whole blood
quickly knocked-up may be, quickly suppliers of OEM direct from the patient, testing with
rigs and prototypes components, water and red food dye is not going to
must be treated with
knocked-up rigs and and supply other help. In fact, it may well result in false
caution. The system prototypes must be services (such confidence in the design, or even lead to
that worked with as packing and a workable concept being abandoned.
the Heath Robinson
treated with caution. sterilisation) that Occasionally the first idea may work
prototype may cease can be utilised. straight away. If this does happen,
to work with a high-spec prototype. In this way, the manufacturer can be a the performance boundaries still
Only after hours of investigation do you great ally during the prototyping phase, will need to be found. More likely,
realise that one of the 0.25-mm holes enabling the project team to create however, is that the system will almost
in the original prototype was, in fact, prototypes that are near, if not identical, work, and achieving that last 20% of
blocked with swarf, making the system to the final product. the performance requirements will
function beautifully… If the conceptual design includes take 80% of the development time.
To address this problem, when it off-the-shelf components, the same Sometimes, the trickiest problems are
comes to the design process for fluid components should be used in the best solved by experimentation and by
handling devices and systems, detailed prototypes and in the final device. playing with the circuit, rather than
design of the fluid path and selection Plenty of time should be spent finding spending hours over a hot CAD station.
of the manufacturing method should and testing the parts at this stage, and Once the fluid circuit is operating
come early. Once a design that works they should be sourced from a company exactly as intended, the repeatability
has been found, the design of the that is able to supply final production and robustness of the design will need
fluid-contact path should be frozen. volumes. Time spent here finding the to be tested. Initially, this may involve
Ideally, the prototype fluid circuit will right components may well reduce the freestyle experimentation, followed by a
be made in the same way as the final overall development time. more structured system characterisation
product—i.e., using the same materials If the perfect off-the-shelf component when the design is finalised.