4. This disease is
This disease is
transmitted by the
transmitted by the
bite of mosquito Aedes
bite of mosquito Aedes
aegypti
aegypti
It’s an acute infectious
It’s an acute infectious
disease, of rapidly
disease, of rapidly
evolving, caused by
evolving, caused by
Flavivirus
Flavivirus
WHAT’S YELLOW FEVER?
It’s called YELLOW beacause one of the symptoms is jaundice
It’s called YELLOW beacause one of the symptoms is jaundice
8. Dengue virus belongs to the family Flaviviridae
Dengue virus belongs to the family Flaviviridae
Virus of DENGUE is transmitted by a
mosquito called Aedes aegypti
9. Cases of Dengue in Peru -- 2011
Cases of Dengue in Peru 2011
• 29 057 cases
*confirmed: 84.22%
*15.78% similar.
• Loreto, Madre de Dios and
San Martin reported 91%
of cases.
10.
11. Dengue yellow fever
nausea vomiting muscle pain joint pain
liver Bleeding gums
headache jaundice
damage and nose
15. DIFFERENT SIGNS AND SYMPTOMS BETWEEN
YELLOW FEVER AND DENGUE
IN DENGUE:
IN DENGUE: dengue
16.
17. AA specific
specific
diagnostic test for dengue
diagnostic test for dengue
fever is needed for rapid
fever is needed for rapid
detection, confirmation of
detection, confirmation of
acute condition, detection
acute condition, detection
of dengue antibodies and
of dengue antibodies and
separation of dengue viral
separation of dengue viral
RNA or protein in tissue
RNA or protein in tissue
specimen or serum.
specimen or serum.
18. Serological Tests
Serological Tests Complex Tests
Complex Tests
If there is four times are
If there is four times are There are some complex tests
There are some complex tests
higher increase in the
higher increase in the called complement fixation
called complement fixation
dengue antibodies between
dengue antibodies between and neutralising antibody
and neutralising antibody
initial and later samples,
initial and later samples, which are not possible in every
which are not possible in every
the infection is confirmed
the infection is confirmed medical centre.
medical centre.
as acute.
as acute.
DIAGNOSTIC
TEST
MAC-ELISA
MAC-ELISA Dengue Virus Isolation
Dengue Virus Isolation
The samples collected initially
The samples collected initially
Separation of dengue virus or
Separation of dengue virus or
and later can be analyzed
and later can be analyzed
detecting dengue viral RNA in aa
detecting dengue viral RNA in
through
through Hemaggulation
Hemaggulation
patient’s sample of serum or
patient’s sample of serum or
Inhibition (HI) for definite
Inhibition (HI) for definite
tissue gives aaconfirmation of the
tissue gives confirmation of the
confirmation or denial of acute
confirmation or denial of acute
infection.
infection.
dengue infection.
dengue infection.
19. Tests Used for a Yellow Fever Diagnosis
If the doctor thinks a person is at risk for
If the doctor thinks a person is at risk for
yellow fever, he or she can order certain tests.
yellow fever, he or she can order certain tests.
Blood tests Cerebrospinal fluid tests
Electrocardiograms (EKGs).
To make aadefinitive diagnosis of yellow fever, the doctor will draw aa
To make definitive diagnosis of yellow fever, the doctor will draw
blood sample and send it to aacommercial or public health laboratory
blood sample and send it to commercial or public health laboratory
for confirmation.
for confirmation.