7. how can differences between individuals such us as SNPs lead to.pdf
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7. how can differences between individuals such us as SNP\'s lead to persistent expression of lactase is some people but not in others? Solution Lactase persistence is the continued activity of the enzyme lactase in adulthood, only function of this enzyme is the digestion of lactose in milk, in most mammal species, the activity of the enzyme is dramatically reduced after weaning. Two mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase expression. C-14010, G-13907, and G-13915, T13910 and A22018 are related to lactase persistence.Schultheis et.al. suggests this trait is strongly associated with a C to T substitution at a polymorphic site 13,910 bp upstream of the lactase gene. As per Swallow DM\'s paper stated that , \"A putative causal nucleotide change has been identified and occurs on the background of a very extended haplotype that is frequent in Northern Europeans, where lactase persistence is frequent. This single nucleotide polymorphism is located 14 kb upstream from the start of transcription of lactase in an intron of the adjacent gene MCM6.\" So if the single nucleotide polymorphism occurs then the lactase persistance is seen in some individuals else not..
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PTMs are chemical alterations to protein structure, typically catalyzed by exceedingly substrate-specific enzymes, which themselves are under strict control by PTMs. They generate a large diversity of gene products because many types of PTMs are covalently attached to amino-acid residues in each protein. For protein post-translational modification analysis at Creative Proteomics, please visit https://www.creative-proteomics.com/services/protein-post-translational-modification-analysis.htm
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The difference in the secretory and co translational pathway in yeast versus humans is that
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horizontal support boards. Behind the fence show a simple house in the background. Make sure
the house is visible between the slats in the fence.
Solution
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Write a Python program that extracts 1000 unique links from Twitter .pdf
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Why is 89 and 93 (-infinity, infinity) and not [7/4,infinity) and [-7,infinity)?
Solution
89. k(x) = (4x -7)1/3 The function k(x) takes all the values on the real number line as x takes
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93. F(x) = (x+7)1/3. The function F(x) takes all the values on the real number line as x takes
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the set of all real numbers, or in interval notation, (- , ). When x = -7, F(x) = 0 and when x < -7,
F(x) is negative. A negative real number can have a third root. For example, the 3rd root of -1 is
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What are the consequences of stakeholder ethics with regards to organizational goals and
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Solution
stakeholders are the people who contributes their services to the firm, they includes; customers,
employees, owners/promoters, media, society, government, suppliers and competitors.
if an organization is considering all the requirements of stakeholders as a whole, it means that it
is doing good. here it should treat all the stakeholders equally, and should not works for one
community or one kind of people to the organization. if the organization works to protect the
rights and requirements of all stakeholders, it means that they are doing good.
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Solution
a) Catalase is an antioxidant that makes the hydrogen peroxide less toxic by converting it into
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What is the weighted average cost of capital for a corporation that finances an expansion project
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What measures have the EU (or member nations) taken to mitigate the current economic
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In last few years,The EU financial and economic policies have been moulded under the
supervision and ratification of the member states to combat the series of economic challenges
that the region has confronted consistently.In this context,we can divide these recent challenges
according to the events that occured in recent past and discuss some of the economic remmedies
that had implemented by the member states either conjointly or separately.Evidently,the
challenges that the EU had faced recently majorly include Brexit issue,Financial Crisis that
culminated in 2008 and sustained,immigration issues and refugee crisis,capital/financial market
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Considering the apprehension of an impending economic collapse due to UK\'s exit from the
EU,there has been much emphasis on resistive policy mechanism from the part of the
administration.It had been apprehended that as Britain has traditionally been a strong economic
force of EU with considerably high contribution of overall GDP in EU,source of high export
revenue for EU as a whole,major source employment to the EU region,attracting significant
foreign investment due to the existence of so many top shot MNCs in Britain and its rapid GDP
growth also contributed notably to the growth and progress of the entire EU
region.Thus,expectedly,the apprehension became stronger that Brexit would lead to massive
economic collapse in EU region through decline in overall GDP nad GDP growth rate,lower
employment rate,restrictions on free flow of capital in the region,undersirable international trade
impacts,reduction in foreign capital and financial investment in the region and so forth.
However,the impact of Brexit has been clearly evident in UK with high inflation rate,decrease in
consumer spending and slow production and output in the country,some of the intial resistive
fiscal and monetary policies adopted by EU could resist the some of the expected
damages.Favorable monetary and labor market policies have restricted the extent of
macroeconomic crisis within the EU nations due to Brexit.In this regard,certain expansionary
monetary and fiscal relief meausers undertaken have been able to restore the production level
and consumer spending or at least ensure improvement amidst the economic threats of
brexit.Furthermore,low oil prices and consistent weaker Euro have safeguarded many EU nations
against the negative trade impacts of Brexit where other member nations are able to continue
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To remove the image link using dom explorer we have to use the following code:
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Today’s world seems to be moving beyond sovereignty and toward supranational leadership to
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Solution
Answer:
The essential issues that are being experienced all inclusive incorporate battle against
psychological warfare, control of expansion, cultivating advancement, guaranteeing strength in
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intelligence the security agents among nations are equipped to able to share and providing
combined forces for peace keeping mission.
Control inflation by ensuring stability in the country currency and good trading relationships. For
development the nation is able to support investors from outside for its growth. Such
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The future value at 4.75% interest, compounded continously for 6 Years, of the countinous
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solar collector to fresh water flowing through the tubes at an average temperature of 60 degree C
at a rate of 15 L/s. The heat exchanger contains 80 brass tubes 1 cm in inner diameter and 1.5 m
in length. The roughness of brass tubing is epsilon 1.5 times 10^-6 m. Determine the pressure
drop across a single tube. Calculate the pumping power required by the tube-side fluid of the
heat exchanger. After operating for a long time. 1-mm-thick scale builds up on the inner
surfaces with an equivalent roughness of 0.4 mm. For the same pumping power input determine
the percent reduction in the flow rate of water through the tubes.
Solution
solution:
1)here for calculating pressure loss is given by
dP=f(L/D)*density*V^2/2
Q=15/80=.1875 l/s or 1.875*10^-4 m3/s
D=.01 m
L=1.5 m
e=1.5*106-6 m
velocity is given by
V=Q*4/pi*D^2=2.3873 m/s
Re=VD/kinematic viscosity=23873.241
here for terbulent flow friction factor is given by
f=1.325/{ln[e/3.7D+5.74/Re^.9]}^2
so we get
f=.02510
here pressure drop is given as
dP=f(L/D)*density*V^2/2
dP=10728.74 N/m2
where pumping power is
W=Q*dP/1000=2.011*10^-3 kw
3)when scale are deposited then flow velocity is given by
reduced diameter=d1=.01-.002=8*10^-3 m
velocity=1.875*10^-4*4/pi*d1=3.7301 m/s
reynolds number is
Re1=29840.8
friction factor is for e1=4*10^-4 m
f1=.07284
pressure drop=dP1=95016.55 N/m2
for same power flow rate is
W=Q1*dP1/1000
Q1=2.1164*10^-5 m3/s
hence percent reduction in flow rate is for single tube
%reduction=(Q-Q1/Q)*100=88.75%.
Research and describe a tool that can be used to test for web server.pdf
Requirement 1. Describe the difference between period costs and product costs. Period costs are
operating costs that are expensed in the accounting period in which they are incurred. Product
costs are all costs of a product that GAAS requires companies to treat as an asset for extemal
financial reporting. These costs are recorded as an asset (inventory) on the balance sheet until the
asset is sold. The cost is then transferred to an expense accountCost of Goods Manufactured on
the income statement. is subtracted from Sales Revenue to determine gross proft. The operating
costs are then On the income statement, Cost of Goods Sold subtracted to determine operating
income. Requirement 2. Classify Lawlor\'s costs as period costs or product costs. If the costs are
product costs, further classify as direct materials, direct labor, or Shaft and handle of weed
trimmer Motor of weed trimmer Factory labor for workers assembling weed trimmers Nylon
thread used by the weed trimmer (not traced to the product) Glue to hold housing together Plant
janitorial wages Depreciation on factory equipment Rent on plant Sales commissions
Administrative salaries Plant utilities Shipping costs to deliver finished weed trimmers to
customers Direct materials Direct materials Direct labor Manufacturing overhead Manufacturing
overhead Manufacturing overhead Manufacturing overhead Manufacturing overhead Period
costs Period costs Manufacturing overhead Period costs
Solution
Requirement 1
Period Costs are operating costs that are expensed in the accounting period in which they are
incurred.
Product Costs are all the cost of a product that GAAP requires companies to treat as an asset for
external financial reporting. These costs are recorded as an asset (inventory) on the balance sheet
until the asset is sold. The cost is then transferred to an expense account (Cost of Goods Sold) on
the income statement. Product costs include direct materials, direct labour, and manufacturing
overhead.
On the income statement, Cost of Goods Sold ( product Cost ) is subtracted from Sales Revenue
to determine gross profit. The period costs are then subtracted from gross profit to determine
operating income.
Requirement 2
Direct Materials
Direct Materials
Direct labour
Manufacturing Overhead
Manufacturing Overhead
Manufacturing Overhead
Manufacturing Overhead
Manufacturing Overhead
Period Cost
Period Cost
Manufacturing Overhead
Period Cost.
Question 11 of 24 In E. coli, three structural Deand enzymes A. D, an.pdf
Question 1. Dscribe the change you observed when you added 1 mL of 0.1 M KSCN to the 2 mL
portion of the diluted solution. Copy the equation from the procedure and explain your
observations in terms of LeChatelier’s Principle. Choose the best answer.
The additional thiocyantate ion shifted the equilibrium toward the products, producing
morehexathiocyanatoferrate(III) lightening the color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
The additional thiocyantate ion shifted the equilibrium toward the reactants, producing
lesshexathiocyanatoferrate(III) and deepening the color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
The additional thiocyantate ion shifted the equilibrium toward the reactants, producing
morehexathiocyanatoferrate(III) lightening the color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
The additional thiocyantate ion shifted the equilibrium toward the products, producing
morehexathiocyanatoferrate(III) and deepening the color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
Question 2. Show your calculations to determine the final volume of the 0.001 M FeCl3 solution.
Choose the best answer.
M1V1 = M2V2.
(0.001 M)V1=(0.1 M)(0.05 L)
V1=0.050 L = 50 mL
M1V1 = M2V2.
(0.001 M)V1=(0.1 M)(0.005 L)
V1=0.500 L = 500 mL
M1V1 = M2V2.
(0.1 M)(0.005 L)=(0.001 M)V2
V2=0.500 L = 500 mL
M1V1 = M2V2.
(0.1 M)(0.0005 L)=(0.001 M)V2
V2=0.050 L = 50 mL
Question 3. Describe the change you observed when you added 1 mL of 0.1 M FeCl3 to the
diluted mixture of 0.001 M FeCl3(aq) and 0.1 M KSCN(aq). Refer to the equation in step 1 and
explain your observations in terms of LeChatelier’s Principle. Choose the best answer.
Additional iron(III) ion shifted the equilibrium toward the products to form the red-colored
hexathiocyanatoferrate(III) complex and the intensity of color increased.color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
Additional iron(III) ion shifted the equilibrium toward the products to form the red-colored
hexathiocyanatoferrate(III) chloride precipitate.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)6Cl3(s).
Additional iron(III) ion caused the equilibrium to shift to the reactants to compensate for the
additional added iron(III), which increased the intensity of the red color.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
Additional iron(III) ion increased the concentration of the red-colored iron(III) ion.
Fe3+(aq) + 6SCN-(aq) Fe(SCN)63-(aq).
Question 4. Predict and then describe what happened when you added HCl(aq) to the copper
nitrate solution. Write down the equation for the reaction. Choose the best answer.
The added hydrogen ion shifted the equilibrium toward the products so that more CuCl42-(aq)
was createdand the solution changed from blue to green.
Cu(H2O)42+(aq) + 4Cl-(aq) CuCl42-(aq) + 4H2O(l).
The added chloride ion shifted the equilibrium toward the products so that more CuCl42-(aq)
was created and the solution changed from blue to green.
Cu(H2O)42+(aq) + 4Cl-(aq) CuCl42-(aq) + 4H2O(l).
The added chloride ion caused the precipitation of CuCl42-(s), which shifted the equilibrium
toward t.
Question 1. Dscribe the change you observed when you added 1 mL of 0.pdf
Question 1 5 pts Given the cash flow diagram below, evaluate the value of \"A\" if the \"F\"
value is $24.000 for an interest rate of 7%. ?? 4A
Solution
Future Value of investents: Year Investment Future Value of Investment of 1 Future
Value of Investment a b c=1.07^(5-a) d=b*c 1 A 1.3108
1.3108 A 2 2A 1.2250 2.4501 A 3 3A 1.1449
3.4347 A 4 4A 1.0700 4.2800 A
11.4756 A Now, As per question, 11.4756 A = $
24,000 or, A = $ 2,091.40 Thus, Value of A $ 2,091.40.
Prove that a group of order 255 is a cyclic.SolutionLet G be a .pdf
Project #8 requires you to find an escape path from a given starting point in a maze. The maze
(or swamp or mine field etc.) is a square 2D array of int. A value of zero in any cell represents a
wall (land mine or quicksand etc.) while a value of one represents a possible step to take. Each
input file will have a line at the top of the file that has the square dimension of the matrix
followed by the drop in point. The drop in point is the row/col pair indicating where you are
dropped into the swamp. You escape the swamp by taking one step at a time to any adjacent
square that is a 1. You are not allowed to step on a zero cell. You must somehow remember
which squares you have already stepped on in a path so that you don\'t get into an infinite loop.
The five input files you are given have cycles and dead ends and valid paths to the edge of the
swamp.
The starter file that you are given has two methods already written for you. The first given
method loads the grid values and generates the 2D int array to hold the 1s and 0s. The second
method echo\'s out the swamp to the screen before calling the method that you must fill in -
which will print all the escape paths.
Do not modify main any more than needed.
Do not modify the given methods that load or print the grid.
You are just to write and call the method(s) that print all escape paths.
the only output you are to write is one line per escape path and it must be in the exact format as
my sample output. If there are no escape paths then your code prints out no additional output.
Your escape path lines may be in a different order than mine but the row,col values must match
exactly in matching lines.
Your program must find and print ALL the escape paths. Lines may be in any order though.
Do not print any other output of any kind other than what my solution demo does.
DO NOT PRINT \"DEAD END\" OR *ANY* OUTPUT IF THERE ARE NO PATHS OUT.
JUST PRINT NOTHING!
input file:
output should look like:
Solution
input0.txt
10 2 3
0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 1 0 1 0
0 0 0 1 0 1 0 1 0 0
0 0 0 1 0 1 1 0 0 0
0 0 1 0 1 0 0 1 0 0
0 1 0 0 1 1 1 1 0 0
0 0 1 0 1 0 1 0 1 0
0 0 0 1 0 1 0 1 0 0
0 0 1 0 1 0 1 0 1 0
0 0 0 0 0 0 0 0 0 0
Project2.java
import java.io.*;
import java.util.*;
public class Project2
{
public static void main(String[] args) throws Exception
{
int[] dropInPt = new int[2]; // row and col will be on the 2nd line of input file;
int[][] swamp = loadSwamp( args[0], dropInPt );
int row=dropInPt[0], col = dropInPt[1];
printSwamp( \"\ SWAMP: dropped in at: [\"+row+\",\"+col+\"]\ \",swamp );
System.out.println(\"\ ESCAPE PATHS:\ \");
// YOUR CODE HERE. DECLARE WHATEVER OBJECTS AND VARIABLES
NEEDED
// CALL YOUR METHOD(s) TO PRINT ALL ESCAPE PATHS
printPath(swamp, dropInPt);
} // END MAIN
// ###################################################
// DO NOT MODIFY THIS METHOD
// ----------------------------------------------------------------
private static void printSwamp(String label, int[][] swamp )
{
System.o.
Choose one field such as academia, health, consulting, business, man.pdf
Choose one field such as academia, health, consulting, business, management, and so on and
discuss the importance of followership in that field.
Solution
A follower can be a personality kind, as a foothold in a very hierarchy, as a role, or as a
collection of traits and behaviors. Studies of followership have created numerous theories
together with an attribute, activity attributes, role, and constructionist theories additionally to
exploring myths or misunderstandings concerning followership.
---Effective followership coaching within the school room is difficult due to media messages that
preference leadership, internal schemas command by students that ignore followership, and
cultural biases against it. undergrad and graduate students are proof against the thought of
followership and followership have been taken as leadership poorly enacted or as subsiding for a
lesser position. In recent years, attitudes have begun to change the students have noted that
following is an expected, healthy a part of a reciprocal relationship in social media which it
failed to carry negative connotations.
Although a student’s contribution within the schoolroom has such high significance, the school
admissions system has nevertheless to seek out the way to acknowledge and reward students who
have ceaselessly created these contributions. on condition that outstanding schoolroom
contributions are neglected, nevertheless play such an important role, it\'s the responsibility of
the school admissions system to seek out the way to spot them.
---In hospitals and tourism, being a good follower is vital for achieving the service-oriented goals
of the many operations.In hospital operations, it\'s typically necessary for followers to figure
severally of their leaders to holdout necessary tasks. it\'s been steered that incorporating
followership into coaching and education in intentional, purposeful ways in which may assist
operations in hospital and tourism.
---Followership, as outlined by Hurwitz (2008), is “accepting or enabling [italics original] the
goal accomplishment of one’s leader”. within the context of franchising, the franchise may well
be seen as an admirer as a result of he or she accepts the franchisor’s business plan and allows
the franchisor’s goal accomplishment through the individual franchise operations. Leaders will
begin by building structure price for followers and followership price could be a method of
incorporating the construct of followership into the organization’s culture, policies, and practices
as a result of leaders have followers it\'s their responsibility to line a vision, build trust, and
encourage the followers with passion and hope.
---The Followership Learning Community (FLC) could be a learning community inside the
International Leadership Organization (ILA) and is “dedicated to the event of information,
competencies, and programs regarding the leader-follower relationship. it\'s the primary such
educational or applies community dedi.
An intercalating agent 1. Inserts between base pairs of the two str.pdf
An intercalating agent: 1. Inserts between base pairs of the two strands of DNA 2. Makes double-
stranded lesions in the DNA 3. Inserts between adjacent base pairs on a single strand of DNA 4.
Commonly causes transversion mutations 5. Makes single-stranded lesions in the DNA
Solution
Chelating agent involves the formation or presence of two or more separate coordinate bonds
between a polydentate (multiple bonded) ligand and a single central atom. Usually these ligands
are organic compounds, and are called chelants, chelators, chelating agents, or sequestering
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a trait is considered discrete when 1-The traits are intermediat.pdf
a trait is considered: discrete when:
1-The traits are intermediate between the recessive and dominant cases
2- the traits are obviously either there or not there [what I guess the answer is]
3- the traits are variable in the population
4- the traits are a result of multiple genes.
when the allele of a trait is incompletely dominant:
1- the dominant trait masks the recessive trait
2- the recessive trait masks the dominant trait
3- the heterozygous individial is the same as the dominant.
4- the heterozygous individual is intermediate between the recessive and the dominant
5- the heterozygous individual expresses both traits.
Solution
A trait is considered discrete when the traits are either there or not there, eg Albinism, cystic
fibrosis, Huntingtons disease, -option 2.
Incomplete dominance is a form of intermediate inheritance where one allele for a specific trait
is not completely expressed over its paired allele. This results in a third phenotype in which the
expressed physical trait is a combination of the phenotypes of both the alleles. Option 4-the
heterozygous individual is intermediate between the recessive and the dominant.
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7. how can differences between individuals such us as SNPs lead to.pdf
- 1. 7. how can differences between individuals such us as SNP's lead to persistent expression of lactase is some people but not in others? Solution Lactase persistence is the continued activity of the enzyme lactase in adulthood, only function of this enzyme is the digestion of lactose in milk, in most mammal species, the activity of the enzyme is dramatically reduced after weaning. Two mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase expression. C-14010, G-13907, and G-13915, T13910 and A22018 are related to lactase persistence.Schultheis et.al. suggests this trait is strongly associated with a C to T substitution at a polymorphic site 13,910 bp upstream of the lactase gene. As per Swallow DM's paper stated that , "A putative causal nucleotide change has been identified and occurs on the background of a very extended haplotype that is frequent in Northern Europeans, where lactase persistence is frequent. This single nucleotide polymorphism is located 14 kb upstream from the start of transcription of lactase in an intron of the adjacent gene MCM6." So if the single nucleotide polymorphism occurs then the lactase persistance is seen in some individuals else not.