The mediastinum is the space within the thorax between the lungs, containing the heart, major blood vessels, esophagus and other structures. It is divided into superior and inferior mediastinum. The superior mediastinum contains the thymus gland, great vessels of the neck, trachea and esophagus. The inferior mediastinum is further divided into anterior, middle and posterior mediastinum by the pericardium. The middle mediastinum contains the heart and pericardium, while the posterior mediastinum contains the descending aorta and esophagus. Infections of the neck can spread into the mediastinum through fascial planes. Tumors can compress mediastinal structures