a simple multi-utility miniature device used as test tube to 3D cell culture ...guo jun chen
IMAPlate 5RC96 is patented and developed by NCL New Concept Lab GmbH in Switzerland. It is a multi-utility miniature analytical platform that is capable of MANUALLY performing up to 96 individual liquid transfer, analysis, reaction and assay simultaneously. The device is compatible with most 96-well plate readers for the measurement and spectral analysis. The IMAPlate 5RC96 can be used as 96-channel self-dosed manual pipette for tiny amount liquid transfer, as a 96-micro long path-length high sensitive cuvette array for UV-VIS-IR spectrum detection with a flexible sample volume of 1 - 25 ul and as a virtual 96-microwell plate for different assays. The IMAPlate has very broad applications in life sciences and diagnostics and fits for both manual operation and automated liquid handling workstation.
Many assays performed in multi-well plate can easily be adapted to the IMAPlate with increased sensitivity and cost saving, for example ELISA, cell adhesion assay, protein quantification and so on. Due to its unique feature, it can also be used for 3D cell culture to prepare micro-tissues and perform subsequent testing and measurement directed in the device. If needed, the micro-tissues or cells in the IMAPlate can easily be transferred to any 96-well plate and even can be spotted on microscope slide directly from the IMAPlate.
توفر شركة تكنوسيرفيس مجموعة أجهزة الكشف عن المعادن Thermo Scientific ™ Sentinel ™ والتي تتميز بأداء كشف عالي الحساسية لجودة منتجك ومدي احتمالية العثور على ملوثات معادن حديدية وغير حديدية وأي ملوثات في الأطعمة والمشروبات وغيرها من المنتجات.
باستخدام تقنيات مبتكرة مثل Multiscan ™ و Selectscan ™ ، تساعد أجهزة الكشف عن المعادن Sentinel الشركات المصنعة على زيادة سلامة وصحة العملاء وتحسين جودة المنتج وزيادة كفاءة الإنتاج.
اكتشف معنا كيف يمكن لمجموعة منتجات Sentinel تلبية احتياجات تطبيقاتك.
أهمية وجود أجهزة الكشف المعادن في خط إنتاجك ؟
1️⃣ أصبح الآن من الشروط الأساسية لدي منظمة الصحة والأغذية لحمايه المستهلك.
2️⃣ ضروري لمنح شهادة الأيزو لمنتجك
3️⃣ ضمان استمرارية البراند الخاص بك في السوق وحصوله علي سمعة طيبة نتيجة ضمان الجودة
تستخدم هذه الاجهزه على خطوط انتاج وتعبئه الاغذيه
(مثل المطاحن و مصانع الالبان والحلويات والبسكويت والشيكولاته والمكرونه والمخللات والخضروات والفواكه المجمده والايس كريم ..وغيرها)
مميزات الجهاز:
◀يمكنه الكشف عن المعادن داخل منتجك خلال مراحل عمليه التصنيع حتى التعبئه وبدقه عاليه
◀ يمكنه رفض كل المنتجات المخالفه لمعايير الجوده وسلامه الغذاء
◀ يتميز الجهاز بالشكل الانسيابي وصغر الحجم
◀الجهاز حاصل على شهاده من هيئه سلامه الغذاء FDA
◀ الجهاز حاصل على IP69K لمقاومه الماء
◀ السير مصنوع من اعلى الخامات جوده والتي تتحمل الاوزان الكبيره
◀ سهل برمجته والتدريب عليه وتوافر قطع الغيار والصيانه
◀ ضمان لمده عام كامل
◀ الجهاز به إنذار صوت وضوء
◀ مهندسين متخصصين للتركيب والتدريب علي الجهاز وحاصلين علي شهادات معتمدة من ThermoFisher
تطبيقات اجهزه الكشف عن المعادن والشوائب :
تستهدف اجهزه الكشف عن المعادن والشوائب (metal detectors وال x-ray) كل شركات ومصانع الاغذيه وقطاع سلامه الغذاء وخطوط الانتاج التي تسعى للحصول على شهادات الايزو والجوده .
تسعى تكنوسيرفيس لخدمه جميع عملائها باحترافيه عن طريق مساعدتهم للوصول للنجاح في جميع المجالات السابقه .
just call us 01116593835
http://technoservice-egypt.com/
We are offering the best dental products online India at the best prices, For buying at the best & minimum prices all over India. For more info, Kindly contact us: 8826879993
Ph No: 011-43022244/55/66
All Dental Clinical Catalog Products Available With Best Prices All Over India. || For More Info:- Ph. No – 011-43022244/55/66 E-mail:- info@aplmedidant.com,
CALL US.
8826879993
a simple multi-utility miniature device used as test tube to 3D cell culture ...guo jun chen
IMAPlate 5RC96 is patented and developed by NCL New Concept Lab GmbH in Switzerland. It is a multi-utility miniature analytical platform that is capable of MANUALLY performing up to 96 individual liquid transfer, analysis, reaction and assay simultaneously. The device is compatible with most 96-well plate readers for the measurement and spectral analysis. The IMAPlate 5RC96 can be used as 96-channel self-dosed manual pipette for tiny amount liquid transfer, as a 96-micro long path-length high sensitive cuvette array for UV-VIS-IR spectrum detection with a flexible sample volume of 1 - 25 ul and as a virtual 96-microwell plate for different assays. The IMAPlate has very broad applications in life sciences and diagnostics and fits for both manual operation and automated liquid handling workstation.
Many assays performed in multi-well plate can easily be adapted to the IMAPlate with increased sensitivity and cost saving, for example ELISA, cell adhesion assay, protein quantification and so on. Due to its unique feature, it can also be used for 3D cell culture to prepare micro-tissues and perform subsequent testing and measurement directed in the device. If needed, the micro-tissues or cells in the IMAPlate can easily be transferred to any 96-well plate and even can be spotted on microscope slide directly from the IMAPlate.
توفر شركة تكنوسيرفيس مجموعة أجهزة الكشف عن المعادن Thermo Scientific ™ Sentinel ™ والتي تتميز بأداء كشف عالي الحساسية لجودة منتجك ومدي احتمالية العثور على ملوثات معادن حديدية وغير حديدية وأي ملوثات في الأطعمة والمشروبات وغيرها من المنتجات.
باستخدام تقنيات مبتكرة مثل Multiscan ™ و Selectscan ™ ، تساعد أجهزة الكشف عن المعادن Sentinel الشركات المصنعة على زيادة سلامة وصحة العملاء وتحسين جودة المنتج وزيادة كفاءة الإنتاج.
اكتشف معنا كيف يمكن لمجموعة منتجات Sentinel تلبية احتياجات تطبيقاتك.
أهمية وجود أجهزة الكشف المعادن في خط إنتاجك ؟
1️⃣ أصبح الآن من الشروط الأساسية لدي منظمة الصحة والأغذية لحمايه المستهلك.
2️⃣ ضروري لمنح شهادة الأيزو لمنتجك
3️⃣ ضمان استمرارية البراند الخاص بك في السوق وحصوله علي سمعة طيبة نتيجة ضمان الجودة
تستخدم هذه الاجهزه على خطوط انتاج وتعبئه الاغذيه
(مثل المطاحن و مصانع الالبان والحلويات والبسكويت والشيكولاته والمكرونه والمخللات والخضروات والفواكه المجمده والايس كريم ..وغيرها)
مميزات الجهاز:
◀يمكنه الكشف عن المعادن داخل منتجك خلال مراحل عمليه التصنيع حتى التعبئه وبدقه عاليه
◀ يمكنه رفض كل المنتجات المخالفه لمعايير الجوده وسلامه الغذاء
◀ يتميز الجهاز بالشكل الانسيابي وصغر الحجم
◀الجهاز حاصل على شهاده من هيئه سلامه الغذاء FDA
◀ الجهاز حاصل على IP69K لمقاومه الماء
◀ السير مصنوع من اعلى الخامات جوده والتي تتحمل الاوزان الكبيره
◀ سهل برمجته والتدريب عليه وتوافر قطع الغيار والصيانه
◀ ضمان لمده عام كامل
◀ الجهاز به إنذار صوت وضوء
◀ مهندسين متخصصين للتركيب والتدريب علي الجهاز وحاصلين علي شهادات معتمدة من ThermoFisher
تطبيقات اجهزه الكشف عن المعادن والشوائب :
تستهدف اجهزه الكشف عن المعادن والشوائب (metal detectors وال x-ray) كل شركات ومصانع الاغذيه وقطاع سلامه الغذاء وخطوط الانتاج التي تسعى للحصول على شهادات الايزو والجوده .
تسعى تكنوسيرفيس لخدمه جميع عملائها باحترافيه عن طريق مساعدتهم للوصول للنجاح في جميع المجالات السابقه .
just call us 01116593835
http://technoservice-egypt.com/
We are offering the best dental products online India at the best prices, For buying at the best & minimum prices all over India. For more info, Kindly contact us: 8826879993
Ph No: 011-43022244/55/66
All Dental Clinical Catalog Products Available With Best Prices All Over India. || For More Info:- Ph. No – 011-43022244/55/66 E-mail:- info@aplmedidant.com,
CALL US.
8826879993
BTY-B2P is based on the differential pressure method, and is professionally applicable to the determination of gas permeability of battery diaphragms, breathable films and other relative polymer products.
Electrostatic disinfection is an innovative method that saves time, energy and costs across the board because it presents a more efficient alternative to traditional cleaning techniques and cleaning solution applications. Below are some of the many benefits of using an electrostatic system.
Reduces the time it takes to cover and disinfect all surfaces and hard-to-reach places by 50% compared to conventional methods
Improves infection control and the spread of viruses such as influenza, MRSA, HIV, and many others
Applies chemicals in a more efficient, uniform and controlled manner, eliminating the dangers of overuse and reducing the number of chemicals used and waste produced
Prevents costly financial burdens associated with contagious healthcare infections
Avoids cross-contamination and the movement of bacteria from one surface to another
Saves chemical solution costs and those associated with long-term cleaning efforts
3 Ways the New Thermo Scientific LC MS Triple Quads Improve Residue AnalysisThermo Fisher Scientific
Learn how the new Thermo Scientific LC-MS triple quadrupole mass spectrometers incorporate unique design features that improve analysis of food matrices for veterinary drug and pesticide residues.
HGA -03 Headspace Gas Analyzer is equipped with professional structural design and high precision sensors. It can provide accurate and fast evaluation of the volumes and proportions of oxygen and carbon dioxide in headspace gases for sealing packages on production lines, at warehouses or in laboratories, to serve as a guide for production and assure shelf life.
SELON HPLC System Introduction ( LC-100 & EX-1600 & EX-1700 )Mandy Yang
SELON new HPLC series, launched in 2018, we have chinese leading technology and economic price.We have infusion pumps, various detectors, manual sampler, automatic sampler, chromatographic column, etc.We can provide suitable configuration according to your different requirements.Please write to us for quotations.At the same time, we are very welcome you to visit our factory.We have own lab and an excellent team of engineers.Please don't hesitate to email us.
export2@selon-group.com
www.selon-group.com
The webinar is all about Ultra High Pressure Liquid Chromatography (UHPLC) performance and how new column technology can deliver the best separation power and be married with the best UHPLC system to ensure an outstanding result. It covers how chromatographers can ensure that even very complex and unfamiliar samples are assayed with the highest scrutiny possible? The webinar discusses how to get the most out of solid core column technology with the right UHPLC system. It covers the use of an extremely long column approach for ultra-high resolution assays and the outlines the importance of robustness and retention time stability.
AWgage-150 measures sheet resistance in ohms per square or milliohms per square. If specific resistivity is known, the thickness of the deposited film layer can be computed from the sheet resistance. The choice of measurement data is easily get in the software. AWgage-150 can accommodate 150mm (6″) wafers as well as the standard 2″, 3″,4″, 5″ wafers without any hardware change.
Allwin21 AWgage-150 Features:
30 years proven Eddy Sheet Resistance Measurement technologies.
Non-contact Sheet Resistance Measurement technologies.
1mΩ/square to 19,990 Ω/square measurement range capability
Touch Screen Monitor and PC w/ Advanced Allwin21 control software.
Wafer carriage travel programmed with internal encoder step motor , without encoder disk.
Consistent wafer-to-wafer process cycle repeatability.
Small footprint and energy efficiency.
Made in U.S.A.
Specifications:
Test Sights: Single center-point, 5-point, or 9-point.5-9
Highly Conductive or Metal Sheet Resistance:
1 to 1,999 mΩ/square
1 to 1,999 Ω/square
Or
10 to 19,990 Ω/square
Highly Conductive or Metal Film ThicknessMinimum: 100 ÅngströmMaximum: Proportional to resistivity. Maximum for a resistivity of 2.7 mW-cm is 270 kÅ (27 mm
Wireless Measurement and Control - AIChE New OrleansJim Cahill
Wireless Measurement and Control - Opportunities for Diagnostics Process Metrics Inferential Measurements and Eliminating Oscillations
Presented by Greg McMillan on March 15, 2011.
Allwin21 Corp. has been focusing on providing solutions and enhancements to the following used semiconductor equipment. These OEM semiconductor equipment have been used in productions and R&D since 1990′s. They’ve each been PROCESS-PROVEN. Allwin21 Corp. can refurbish and/or upgrade these OEM systems with Allwin21′s comparable integrated process control system with PC, solid 3-axis robotic wafer transfer system (if applicable), and new critical components to achieve the goal of giving our customers a production edge with right cost.
We have been doing upgrade for many production proven equipment, such as Perkin-Elmer 2400, Perkin-Elmer 4400, Perkin-Elmer 4410, Perkin-Elmer 4450, Perkin-Elmer 4480, Matrix 105 , Matrix 106, Matrix 303, Matrix 303, Matrix 403, Matrix 205, Matrix 101, Matrix 102, Matrix 103, Matrix 104,Tegal 901e, Tegal 903e, Lam Research LAM AutoEtch 490, Lam AutoEtch 590, Lam AutoEtch 690, Branson/IPC 2000, Branson IPC 3000, Branson/IPC 4000, Gasonics Aura 3000, Gasonics Aura 3010, Gasonics L3510, Gasoncis Aura 1000, Gasonics AE 2001, AG Associates Heatpulse 610, AG Associates Heatpulse 410, AG Associates Minipulse 310, AG Associates Heatpulse 210 on the field for many cases. The reliability have been improved a lot for most of the tools after upgrading. We designed the upgrade kits for these working tools that can do plug and play and most of them only need 2 to 3 days include training. For PE sputter, since it is a little complicated, but we still target to upgrade within one week include training if the machine without other problems.
Why upgrade your old used semiconductor process equipment ?
Low cost solution of obsolete components and parts.
Use new air cooling RF generator to replace the obsolete water cooling RF Generator, avoiding water flood in Fab/Lab.
Use new integrated solid robotic wafer transfer to replace the obsolete index/frog robotic wafer transfer
Requirement of stability of the system
Requirement of network function (GEM/SECSII).
Requirement of PC control for data storage.
Requirement of GUI.
Requirement of more precise control.
Requirement of better repeatability, uniformity.
Requirement of easier maintenance, calibration, and trouble shooting.
BTY-B2P is based on the differential pressure method, and is professionally applicable to the determination of gas permeability of battery diaphragms, breathable films and other relative polymer products.
Electrostatic disinfection is an innovative method that saves time, energy and costs across the board because it presents a more efficient alternative to traditional cleaning techniques and cleaning solution applications. Below are some of the many benefits of using an electrostatic system.
Reduces the time it takes to cover and disinfect all surfaces and hard-to-reach places by 50% compared to conventional methods
Improves infection control and the spread of viruses such as influenza, MRSA, HIV, and many others
Applies chemicals in a more efficient, uniform and controlled manner, eliminating the dangers of overuse and reducing the number of chemicals used and waste produced
Prevents costly financial burdens associated with contagious healthcare infections
Avoids cross-contamination and the movement of bacteria from one surface to another
Saves chemical solution costs and those associated with long-term cleaning efforts
3 Ways the New Thermo Scientific LC MS Triple Quads Improve Residue AnalysisThermo Fisher Scientific
Learn how the new Thermo Scientific LC-MS triple quadrupole mass spectrometers incorporate unique design features that improve analysis of food matrices for veterinary drug and pesticide residues.
HGA -03 Headspace Gas Analyzer is equipped with professional structural design and high precision sensors. It can provide accurate and fast evaluation of the volumes and proportions of oxygen and carbon dioxide in headspace gases for sealing packages on production lines, at warehouses or in laboratories, to serve as a guide for production and assure shelf life.
SELON HPLC System Introduction ( LC-100 & EX-1600 & EX-1700 )Mandy Yang
SELON new HPLC series, launched in 2018, we have chinese leading technology and economic price.We have infusion pumps, various detectors, manual sampler, automatic sampler, chromatographic column, etc.We can provide suitable configuration according to your different requirements.Please write to us for quotations.At the same time, we are very welcome you to visit our factory.We have own lab and an excellent team of engineers.Please don't hesitate to email us.
export2@selon-group.com
www.selon-group.com
The webinar is all about Ultra High Pressure Liquid Chromatography (UHPLC) performance and how new column technology can deliver the best separation power and be married with the best UHPLC system to ensure an outstanding result. It covers how chromatographers can ensure that even very complex and unfamiliar samples are assayed with the highest scrutiny possible? The webinar discusses how to get the most out of solid core column technology with the right UHPLC system. It covers the use of an extremely long column approach for ultra-high resolution assays and the outlines the importance of robustness and retention time stability.
AWgage-150 measures sheet resistance in ohms per square or milliohms per square. If specific resistivity is known, the thickness of the deposited film layer can be computed from the sheet resistance. The choice of measurement data is easily get in the software. AWgage-150 can accommodate 150mm (6″) wafers as well as the standard 2″, 3″,4″, 5″ wafers without any hardware change.
Allwin21 AWgage-150 Features:
30 years proven Eddy Sheet Resistance Measurement technologies.
Non-contact Sheet Resistance Measurement technologies.
1mΩ/square to 19,990 Ω/square measurement range capability
Touch Screen Monitor and PC w/ Advanced Allwin21 control software.
Wafer carriage travel programmed with internal encoder step motor , without encoder disk.
Consistent wafer-to-wafer process cycle repeatability.
Small footprint and energy efficiency.
Made in U.S.A.
Specifications:
Test Sights: Single center-point, 5-point, or 9-point.5-9
Highly Conductive or Metal Sheet Resistance:
1 to 1,999 mΩ/square
1 to 1,999 Ω/square
Or
10 to 19,990 Ω/square
Highly Conductive or Metal Film ThicknessMinimum: 100 ÅngströmMaximum: Proportional to resistivity. Maximum for a resistivity of 2.7 mW-cm is 270 kÅ (27 mm
Wireless Measurement and Control - AIChE New OrleansJim Cahill
Wireless Measurement and Control - Opportunities for Diagnostics Process Metrics Inferential Measurements and Eliminating Oscillations
Presented by Greg McMillan on March 15, 2011.
Allwin21 Corp. has been focusing on providing solutions and enhancements to the following used semiconductor equipment. These OEM semiconductor equipment have been used in productions and R&D since 1990′s. They’ve each been PROCESS-PROVEN. Allwin21 Corp. can refurbish and/or upgrade these OEM systems with Allwin21′s comparable integrated process control system with PC, solid 3-axis robotic wafer transfer system (if applicable), and new critical components to achieve the goal of giving our customers a production edge with right cost.
We have been doing upgrade for many production proven equipment, such as Perkin-Elmer 2400, Perkin-Elmer 4400, Perkin-Elmer 4410, Perkin-Elmer 4450, Perkin-Elmer 4480, Matrix 105 , Matrix 106, Matrix 303, Matrix 303, Matrix 403, Matrix 205, Matrix 101, Matrix 102, Matrix 103, Matrix 104,Tegal 901e, Tegal 903e, Lam Research LAM AutoEtch 490, Lam AutoEtch 590, Lam AutoEtch 690, Branson/IPC 2000, Branson IPC 3000, Branson/IPC 4000, Gasonics Aura 3000, Gasonics Aura 3010, Gasonics L3510, Gasoncis Aura 1000, Gasonics AE 2001, AG Associates Heatpulse 610, AG Associates Heatpulse 410, AG Associates Minipulse 310, AG Associates Heatpulse 210 on the field for many cases. The reliability have been improved a lot for most of the tools after upgrading. We designed the upgrade kits for these working tools that can do plug and play and most of them only need 2 to 3 days include training. For PE sputter, since it is a little complicated, but we still target to upgrade within one week include training if the machine without other problems.
Why upgrade your old used semiconductor process equipment ?
Low cost solution of obsolete components and parts.
Use new air cooling RF generator to replace the obsolete water cooling RF Generator, avoiding water flood in Fab/Lab.
Use new integrated solid robotic wafer transfer to replace the obsolete index/frog robotic wafer transfer
Requirement of stability of the system
Requirement of network function (GEM/SECSII).
Requirement of PC control for data storage.
Requirement of GUI.
Requirement of more precise control.
Requirement of better repeatability, uniformity.
Requirement of easier maintenance, calibration, and trouble shooting.
Brosur 5128A RHapid-Cal Humidity Generator - Fluke Calibration. Fast, portable humidity probe and logger calibration with accredited 1% RH system accuracy.
Info lebih lanjut hubungi Siwali Swantika, Jakarta : 021-45850618 | Surabaya : 031-8421264. Distributor Fluke Calibration di Indonesia
Utilizing an Aluminum Oxide sensor 600 times more sensitive than conventional sensors
The 8800 series uses field proven aluminum oxide (Al2O3) sensing technology to accurately detect trace moisture on either a continuous or spot checking basis.
We manufacture and export Laboratory Testing Equipment using supreme quality material and the advanced technology. These are used in general laboratory, biotechnology/microbiology, pathology, entomology, pharmaceuticals, seed and soil testing, water testing, meteorology food processing. These entire laboratory testing equipment are available at the competitive prices.
Parvovirus Filtration Best Practices - 25 Years of Hands-On ExperienceMilliporeSigma
In this webinar, you will learn:
- how to measure filter performance and capacity,
- how to optimize filter virus removal capability,
- and avoid potential pit-falls
Detailed description:
This webinar will cover all aspects of parvovirus filtration best practices: process development/ optimization, pilot scale-up, and validation and explain the important connections between these activities. The rationale for the recommended best practices will be explained by discussing the underlying mechanisms that control filter performance.
Similar to Development of Pfizer's Third Generation Turbidimetric Solubility Assay - An Engineering Perspective (20)
Automating Data Analysis with Excel Bio-IT World 2018Brian Bissett
Automating Data Analysis with Excel was a Short Course Prepared for Bio-IT 2018 and Presented by Brian Bissett at Bio-IT World Conference on May 15, 2018 in Boston, MA.
Data Analytics of Strategic Information Technology Asset ReviewsBrian Bissett
Data Analytics of Strategic Information Technology Asset Reviews in the Office of Investment Management (OIM) Component ofat the Social Security Administration (SSA).
ElogDoct: A Tool for Lipophilicity Determination in Drug Discovery. 2. Basic ...Brian Bissett
I received a nice acknowledgement in this paper.
ElogDoct: A Tool for Lipophilicity Determination in Drug Discovery. 2. Basic and Neutral Compounds
Franco Lombardo, Marina Y. Shalaeva, Karl A. Tupper, and Feng Gao
Molecular Properties Group and Mathematical and Statistical Sciences Group, Pfizer Global Research and Development
ElogPoct: A Tool for Lipophilicity Determination in Drug DiscoveryBrian Bissett
ElogPoct: A Tool for Lipophilicity Determination in Drug Discovery
Franco Lombardo,Marina Y. Shalaeva, Karl A. Tupper,Feng Gao, and Michael H. Abraham
Molecular Properties Group and Mathematical and Statistical Sciences Group, Central Research Division,
Pfizer Inc., Groton, Connecticut 06340, and Department of Chemistry, University College London, 20 Gordon Street,
London, United Kingdom WC1H OAJ
Physicochemical Profiling In Drug ResearchBrian Bissett
Physicochemical and Biological Profiling in Drug Research ElogD(7.4) 20,000 Compounds Later: Refinements, Observations and Applications
Franco Lombardo, Marina Y. Shalaeva, Brian D. Bissett and Natalya Chistokhodova.
Molecular Properties Group, PGRD Groton Laboratories, Groton, CT 06340, U.S.A.
Addressable Location Indicator Apparatus and MethodBrian Bissett
Addressable Location Indicator Apparatus and Method. Patent for device which provides audio and visual location indicators when triggered by a 911 call or other event.
Bio-IT World 2009: Adjusting Information Flow from In-house HTS to Global Out...Brian Bissett
Adjusting Information Flow from In-house HTS to Global
Outsourcing Partners
Brian Bissett , Staff Scienti st, Molecular Properti es, Pfi zer
This talk will describe the benefi ts and pitf alls of working with a single supplier for screening
services, methods for determining if reliable data is being generated by an outsourcing partner,
and various mechanisms of acti on for manipulati ng, transferring, and integrati ng data into the
corporate environment from a foreign entity.
Chemists need numerous measurements quickly to assess the potential of a given compound within a therapeutic area. Instrumentation is expensive and of limited availability in even the most well funded organizations. The ability to share instrumentation helps mitigate equipment costs but poses special challenges to allow access and use by everyone across an organization. A solution to create open access purification equipment is presented using a Z180 microprocessor, touch screen interface, and an embedded system program written in C.
Development of Pfizer's Third Generation Turbidimetric Solubility Assay - An Engineering Perspective
1. Development of Pfizer's Third Generation Turbidimetric Solubility Assay - An Engineering Perspective Brian Bissett Molecular Properties Group Pfizer Global R&D Groton CT
29. Testing Performance of the New Assay: First a standard had to be created which would add a known quantity of Turbidity (NTUs) with each addition to the test solution (H 2 0) contained within the cuvette. Formula (from Hach Manual):
30. Testing Performance of the New Assay: Example: A single 1.0 µL addition of 1000NTU solution to a cuvette with a total volume of 2.5 mL.
31.
32. Revising the Hach 2100N Turbidimeter Specs Revised Hach 2100N Turbidimeter Specifications: * The standard deviation of each successive addition was 0.001 NTUs. Original Hach 2100N Turbidimeter Specifications: 0.2 ±0.003* Repeatability .066 0.001 Resolution True NTU Value Displayed NTU Value Measurement N/A ±0.01 or 1.0% > of Repeatability N/A 0.001 Resolution True NTU Value Displayed NTU Value Measurement
36. Parallel Run (2483B Assay) “Non-Ideal” Conditions Although 40% of the compounds had a different solubility, more often than not (75%) the difference was only 5 - 10 µg/µL.