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Jan Eite Bullema
version 2011
Introduction Micro-
and Nano Technolgy
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
2Jan Eite Bullema
Reference Books
Reader:
Introduction Micro- and Nano Technology, J.E. Bullema
Further reading:
An Introduction to Micro Electro Mechanical Systems Engineering,
Nadim Maluf, ISBN 0-89006-581-0, 2004
Comprehensive Microsystems, Yogesh B.Gianchandani , 2007
Fundamentals of Micro System Packaging, Rao Tummala, 2001
Micro and Nanomanufacturing, Mark Jackson, 2010
Micro Systems Technology, Wolfgang Menz, 2001
Nano-Bio- Electronic, Photonic and MEMS Packaging, C.P. Wong 2010
3Jan Eite Bullema
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
4Jan Eite Bullema
Definition of Micro Systems Technology
MEMS/ Micro Systems Technology is simultaneously a toolbox, a
physical product, and a methodology, all in one:
• It is a portfolio of techniques and processes to design and create
miniature systems.
• It is a physical product often specialized and unique to a final
application one can seldom buy a generic MEMS / MST product at
the neighborhood electronics store.
• “MEMS / MST is a way of making things,” reports the Microsystems
Technology Office of the United States DARPA. These “things”
merge the functions of sensing and actuation with computation and
communication to locally control physical parameters at the
microscale, yet cause effects at much grander scales.
5Jan Eite Bullema
Definition of Nanotechnology
The U.S. National Nanotechnology Initiative gives the following defining
features of nanotechnology:
1. Nanotechnology involves research and technology development at
the 1nm-to-100nm range.
2. Nanotechnology creates and uses structures that have novel
properties because of their small size.
3. Nanotechnology builds on the ability to control or manipulate at the
atomic scale.
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The Micro and Nano meter domain
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Hair Flake EggLouse
Diode
Solder-
line
Digital
Mirror
Transistor
IC line
(157 nm))
Pore
1 mm 0,1mm 0,01mm 1mu 0,1mu
Atom
(Co on Pt)
Back Finger Nail Bacteria DNA
PCB ICTelevision
Quantum
structure
Buckey
Ball
Semen
1m 0,1m 0,01mu 1nm 0,1nm0,01m
BIOLOGICAL Scale
TECHNOLOGICAL Scale
History Micro and Nano Technology: Feynman
The origin of the concept of micro and nano technology is the speech
‘There is plenty of room at the bottom’ given by Richard Feynman for
the American Society of Physics on December 29, 1959.
Feynman argued in his lecture that one would be able to do amazing
things by decreasing the size.
• Why cannot we write the entire 24 volumes of the Encyclopedia
Brittanica on the head of a pin?
• He also presented the "weird possibility" of "swallowing the doctor"
This concept involved building a tiny, swallowable surgical robot by
developing a set of one-quarter-scale manipulator hands slaved to
the operator's hands to build one-quarter scale machine tools
analogous to those found in any machine shop.
8Jan Eite Bullema
History Micro and Nano Technology: Taniguchi
"‘Nano-technology’ mainly consists of the processing of separation,
consolidation, and deformation of materials by one atom or one
molecule."
9Jan Eite Bullema
History Micro and Nano Technology: Drexler
Eric Drexler, a student of Feynman, wrote in 1986, Engines of Creation:
The Coming Era of Nanotechnology. Describing self-replicating nano-
assemblers building objects one atom at a time.
10Jan Eite Bullema
History MNT: Binning and Rohrer
Binnig and Rohrer at IBM Zurich invented the scanning tunneling
microscope (STM) the first instrument to generate real-space images of
surfaces with atomic resolution. This discovery opened up the
important new field of nanotechnology and was recognized by the 1986
Nobel Prize in Physics. Subsequently, the atomic force microscope
(AFM) was developed. STM and AFM enabled not only the imaging of
individual atoms, but also the manipulation of a single atom.
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History Micro and Nano Technology: Smalley
Richard Smalley, is one of the scientists that is credited with
discovering buckyballs. Smalley and his co-workers, produced the
buckyballs in a device by vaporizing carbon with a laser and allowing
the carbon atoms to condense.
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History Micro and Nano Technology: Geim
Andre Geim and Konstatin Novoselov discovered graphene.
Graphene is a 2D mono layer of carbon, with remarkable physical
properties. Extreme mechanical strength, optical transparent, hermetic,
excellent electrical conduction. Graphene is already produced in
industrial quantities for display applications. As graphene is electrical
conductive and transparent (98% per carbon layer)
13Jan Eite Bullema
Market Expectations: Perspective
2010 Estimates:
World Total Business ~ 55,000 Billion USD
Electronics Market ~ 1,000 Billion USD
GDP the Netherlands ~ 650 Billion USD
Semiconductor Market ~ 350 Billion USD
PhotoVoltaic Market ~ 40 Billion USD
Turnover Philips Electronics ~ 33 Billion USD
MEMS/MST Market ~ 7 Billion USD
Turnover ASML ~ 5,4 Billion USD
Nano Materials Composites ~ 0,5 Billion USD
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Market Expectations: MEMS / MST Market
(Source PCB May 2011)
15Jan Eite Bullema
Sales M$ MEMS family Major Market
Texas Instruments
Hewlett Packard
Robert Bosch
STM Microelectronics
Panasonic
Seiko Epson
Canon
Denso
Freescale Semicond.
Avago Technologies
856
807
637
600
376
305
293
265
240
226
Electro Optic
Electro Fluidic
Electro Mech.
Electro Mech.
Electro Fluidic
Electro Fluidic
Electro Fluidic
Electro Mech.
Electro Mech.
Various
Projection / mobile
Ink jet printer cartridge
Airbag accelerometer
Airbag / Game acceler.
Ink jet printer cartridge
Ink jet printer cartridge
Ink jet printer cartridge
Airbag Accelerometer
Airbag Accelerometer
Various
1. Ink jet cartridges, almost $2B
2. Airbag and gaming accelerometer, $1.8B
3. Projection, over $800M
Market Expectations: MEMS / MST Market
(Source Yole August 2011)
16Jan Eite Bullema
Sales M$ MEMS family Major Market
Texas Instruments
Hewlett Packard
Robert Bosch
STM Microelectronics
Panasonic
Seiko Epson
Canon
Denso
Freescale Semicond.
Avago Technologies
856
807
637
600
376
305
293
265
240
226
Electro Optic
Electro Fluidic
Electro Mech.
Electro Mech.
Electro Fluidic
Electro Fluidic
Electro Fluidic
Electro Mech.
Electro Mech.
Various
Projection / mobile
Ink jet printer cartridge
Airbag accelerometer
Airbag / Game acceler.
Ink jet printer cartridge
Ink jet printer cartridge
Ink jet printer cartridge
Airbag Accelerometer
Airbag Accelerometer
Various
1. Ink jet cartridges, almost $2B
2. Airbag and gaming accelerometer, $1.8B
3. Projection, over $800M
MEMS and Sensors in Mobile Phones
(Source Yole August 2011
17Jan Eite Bullema
Market Expectations: Medical MNT Devices
The total market for Medical Devices is estimated as follows:
Drugs and drug delivery 80 B USD
Blood Analyis 22 B USD
Heart Pacemakers & other implants 16 B USD
Endoscopes and MIS tools 5 B USD
Hearing Aids 4 B USD
DNA & Lab on a Chip 1,2 B USD
Micro and Nano Technology based Products accounts for an estimated
7 B USD, components account for 326 M USD.
www.tft-ltd.co.uk
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Market Expectations: Dutch MNT Companies
Company Product / Service
Aquamarijn Micro sieves
ASMI Various equipment
ASML Wafer stepper
Bronkhorst High Tech Flowsensors
C2V / Thermo fisher micro Gas chromatography
Cavendish Kinetics Non volatile memory
Cytocentrics Patch Clamping
Chemtrix Process intensification
EPCOS RF Switches
Fei Company Electron microscopy
Fluxxion Micro sieves
19Jan Eite Bullema
Market Expectations: Dutch MNT Companies
Company Product / Service
Friesland Foods Application of micro fluidics in foods
Holst Institute System in Package development
IMS Micro Assembly Equipment
Levitor ALD Equipment
Lionix Development of technologies
Mapper Lithographic Equipment
Medspray Aerosol dispensing
Medtronic Maastricht Medical equipment , pacemakers
Microflown Acoustic pressure measurement
Mikronit Lab-on-a-chip
Miplazza Open innovation research facility
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Market Expectations: Dutch MNT Companies
Company Product / Service
Nanomi Functional Emulsions
NT MDT Scientific Equipment for Nanotechnology
NTS Ter Strake Equipment for Large Area Printing
NXP Oscillators, BAW filters
Oce Ink jet printing
Phoenix Software
Philips Electronics Various applications
Pie Medical Ultrasonic imaging
Sensata Pressure sensors
Sentron Solid State pH sensor
SolayTech ALD Equipment
21Jan Eite Bullema
Market Expectations: Dutch MNT Companies
Company Product / Service
Solmates Pulsed Laser Deposition
Tempress Production Equipment, ovens
TNO Development of technology
Wetsus Sustainable water technology
XiO Photonics Optical switching
Xensor Integration Hall sensors
MinacNed is a Dutch interest group that brings companies together in this
field. Regular meetings are organized for interested parties. A yearly
conference Micro Nano Conference is organized, mostly in November of a
year.
http://www.minacned.nl/home.html
22Jan Eite Bullema
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
23Jan Eite Bullema
MEMS: Materials and Material Properties
Silicon
Silicon Oxide and Nitride
Thin metal films
Polymers
Other materials and substrates
Silicon Carbide, Gallium Arsenide, Shape Memory Alloys
Important properties and physical effects
Piezoresistivity, Piezoelectricity, Thermoelectricity, Hall Effect
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Silicon as a Mechanical Material
Kurt Petersen 1982
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Mechanical Properties of Crystalline Silicon
Silicon is hard and brittle.
Yield strength of 7 G Pa
(equivalent to 700 kg on 1 square millimetre)
Young modulus is dependent on the crystal orientation.
Average 160 GPa (for a (100) wafer E110 = 169 GPa E100 = 130
GPa)
Mechanical properties are influenced by dopants
(e.g. introduction of internal stress)
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Properties of Silicon
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Silicon is a Semiconductor
A semiconductor is a material with an electrical conductivity that is
intermediate between that of an insulator and a conductor.
A semiconductor behaves as an insulator at very low temperature, and
has an appreciable electrical conductivity at room temperature although
much lower conductivity than a conductor.
Bandgap
Diamont (C) 5,9 eV
Gallium Arsenide (GaAs) 1,42 eV
Silicon (Si) 1,14 eV
Germanium (Ge) 0,7 eV
Tin (Sn) 0,01 eV
Grafeen (C) 0 eV (halfmetal)
A bandgap below 3 eV is associated with a semiconductor
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Impurity Doping
Impurity doping. Introducing into a semiconductor material impurities of
foreign atoms (dopants) in relative dilute concentrations
Relative dilute is 10 13 - 10 20 foreign atoms / cm3
The impurities alter the electrical properties of the semiconductor. At
room temperature the carrier concentration is nearly equal to the
dopant concentration.
If the dopant is n-type (Arsenic, Phosphorus) there is an excess of
electrons. For p-type there is an excess of holes (dopant Boron)
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Electron Speeds in Various Semiconductors
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Resistivity of Doped Silicon
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Availability of Silicon
Three forms of Silicon are relevant for MEMS
- Crystalline
- Poly Crystalline / poly silicon
- Amorphous
Crystalline silicon is available in circulair wafers
100 mm (4''), 150 mm (6''), 200 mm (8'') and 300 mm (12")
450 mm is expected in the near future
100 mm wafer has a thickness of 525 micron
150 mm wafer has a thickness of 650 micron
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Miller Indices
Orientations in planes are often described in so-called Miller indices
[100] x,y,z vector orientation
<100> 6 directions +x,-x,+y,-y,+z,-y
(111) a plane  on the [111] vector
{111} describes all 8 equivalent (111) planes
Planes and there orientations
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Anisotropic Properties of Silicon
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(a) face view (100); (b) edge view (110); (c) vertex view (111).
Three crystallographic planes and their Miller indexes
Four of the eight equivalent (111) planes in the {111} family.
Anisotropic Properties of Silicon
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Silicon Wafers
Material manufacturers cut thin circular
wafers from silicon boules along specific
crystal planes. The cut plane - the top
surface of the wafer - is known as the
orientation cut, and is encoded on the
wafer itself in the form of a primary and
a secondary flat located on the side of
the wafer.
Commercially available wafers are predominantly of {100} orientation,
which is the preferred orientation cut for CMOS technology. In addition
to the cut impurity doping (p or n) and electrical resistivity
(in Ohm m) are specified by the supplier
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KOH Etch of Silicon
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The etch rate of silicon
with KOH depends on:
- the concentration
of the KOH solution
- the temperature
- the Si crystal orientation
Poly Silicon
Usually deposited as layer or thin film (5 micron) on a surface.
It is used as:
- micromechanical structure (e.g in accelerometer of Analog Devices)
- electrical interconnect
- thermocouples
- p-n junction
Mature technology to create planar micro mechanical structures
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Poly Silicon an Amorphous Silicon
The mechanical properties vary with deposition conditions, but in
general they are the same as for single-crystal silicon
Normally both suffer from intrinsic stress (hundreds of M Pa) which
requires annealing at elevated temperatures (> 900 °C)
Beams of poly silicon or amorphous silicon that have not been
subjected to a careful stress annealing step can curl up under the effect
of intrinsic stress
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Material Properties of Crystaline Silicon
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Interesting Properties of Silicon
Silicon conducts heat circa 100 times better than glass.
Silicon does not function as a Laser (as GaAs for instance does), but
can interact with light and function as a detector.
Silicon is transparent above wavelengths of 1,1 micron.
Silicon reflects light below circa 400 nm (Bleu) at 60 %
Above 500 degrees °C Silicon becomes soft,
plastic deformation sets in.
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Interesting Properties of Silicon
Silicon is resistant to most chemicals (e.g freon or brake fluids)
Interaction with gasses, chemicals, biological fluids, and enzymes
remains subject of studies
In medicine and biology there are on-going studies to evaluate silicon
for chronic medical implants. Preliminary medical evidence indicates
that silicon is benign in the body and does not release toxic substances
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Reflectivity of Silicon
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Selected Properties of Silicon
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Properties of Silicon Oxide
SiO2 Softens above 700 degrees Celsius.
Important that it is electrically insulating, unlike germanium oxide which
oxide is also soluble in water. Gallium Arsenide which oxide can not be
grown appreciably.
Various forms of SiO2 and SiOx, silicate glass are used in
micromachining due to their excellent electrical and thermal insulation
properties.
Also often used as sacrificial layer in surface micromachining
processes, because they can be preferentially etched with hydrofluoric
acid (HF) which is selective to Silicon
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Etching of SiO2 in KOH
KOH etching of silicon dioxide is observable. The etch rates are
considerably slower (1-2 orders of magnitude) than that of silicon but
should be considered when deep etching is being done.
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Silicon On Insulator (SOI)
SOI wafer, where the top single crystalline silicon layer (device layer)
on an oxide film(buried oxide) is fabricated on a silicon wafer (handle
wafer), is widely used in microsystems as well as in semiconductor
devices.
In microsystems, the most attractive feature is that the single crystalline
silicon can be used as structural materials. In surface micromachined
devices.
Relatively thick SOI wafers, whose device layer thickness is more than
a few microns, are widely used in accelerometers, vibrating
gyroscopes, and micromirrors.
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Properties of Silicon Nitride
Si3N4, SiyNx is also widely used as an insulation thin film, it has also
excellent properties as a barrier against mobile ion diffusion. In
particular sodium and potassium ions as found in biological
environments
Its Young modulus is higher than that of silicon and can be controlled
by the specifics of the deposition process
Silicon nitride is an effective masking material in many alkaline etching
solution
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Etching of Silicon Nitride in KOH
KOH etching of silicon nitride was not observed in the study.
Therefore, the silicon nitride etch rate is under 1 nanometer per hour if
it etches at all. If silicon nitride is being used as a mask for silicon
etching, potential etching of the silicon nitride need not be taken into
consideration.
J. Electrochem. Soc. Vol 137, 11, Nov 1990, 3612-3632.
49Jan Eite Bullema
Thin Metal Films
Metal  .cm) Typical Areas of Application
Ag 1.58 Electrochemistry
Al 2.7 Electrical Inteconections
Optical reflection visible & infrared
Au 2.4 High Temp. Electrical Interconnect
Optical reflection infrared
Electrochemistry
Cr 12.9 Intermdiate Adhesion Layer
Cu 1.7 Low Resisitivity Interconnects
ITO 300 - 3000 Transparent Conductive Layer
W 5.5 High Temperature Interconnects
50Jan Eite Bullema
Thin Metal Films
Metal  .cm) Typical Areas of Application
Pd 10.8 Electrochemistry
Solder Wetting layer
Permalloy - Magnetic Transducing
Pt 10,6 Electrochemistry
Electrodes for Bio-potential
SiCr 2000 Thin Laser Trimmed Resistor
SnO2 5000 Chemo-resistance Gas Sensors
TaN 300 - 500 Negative TCR
TiNi 80 Shape Memory Alloy
TiW 75 - 200 Intermediate Adhesion Layer
Near Zero TCR
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Thin Metal Films
Metal  .cm) Typical Areas of Application
Ir 5.1 Electrochemistry
Micro Electrodes Bio-potential
Ni 6.8 Magnetic Transducing
NiCr 200 - 500 Laser-trimmed resistor
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Polymers (SU8)
In silicon micromaching polymers are often deposited in thin layers
from a few nanometers to hundreds of microns
Special photoresists (e.g. SU-8) can be brought up to 1000 micron
thick.
Hardening under UV light produces rigid structures.
Spin on organic polymers are general limited in their application
due to shrinkage due to solvent evaporation
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SU8
SU-8 is a negative-tone photoresist chemically amplified resist
system with excellent sensitivity and high aspect ratios. The
primary applications are micro fabricated mechanical structures
(MEMS) and other microsystems.
Examples are sensors, microfluidic components, electronic coils, inkjet
print head nozzles, MR and GMR heads, multichip modules, actuators,
LCD spacers and moulds for plastic, stamps for hot embossing
and electroplating
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PolyDiMethylSiloxane (PDMS)
Polydimethylsiloxane is one of the most widely used polymers in
MEMS, especially in microfluidic and bioMEMS. It belongs to a class of
polymers called silicones, which are synthetic polymers containing a
Si–O backbone.
Silicones are different from most other polymers in that the backbone
chain of atoms is silicon rather than carbon. Silicones are very
compliant and have been used as the deformable membrane in valves,
as well as being a common die-attach material in packaging.
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Glass, Quartz
Glass and silicon fit together well.
Close match of CTE and suitable for anodic bonding
Quartz has as an extra advantage that it shows piezo electrical
behaviour
Machining can be done by:
- HF etching,
- ultrasonic machining or
- powder blasting
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Silicon Carbide and Diamond
Both materials offer extraordinary hardness and resistance to harsh
environments. Micro machining of both materials is still in its infancy
Both materials demonstrate piezoresistive properties
Silicon carbide is sometimes used as a coating material for harsh
environments
Bandgap of SiC is 3,03 eV
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III-V Semiconductors
Very well suitable for manufacture of lasers and other optical devices
Use in RF devices and high speed electronics. GaN is becoming more
important in LED applications and power electronic applications.
• GaAs
• InP
• AlGaAs
• GaN
• InGaN
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Smart Memory Alloys
Invented in 1951 AuCd alloy
The material remembers its original form after being strained and
deformed. Alloys:
• TiNi
• Cu Al Ni
• FeNi
• Fe Pt
Practical limitation lies in the transition temperature.
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Shape Memory Alloys
A shape memory alloy (SMA) (also known as memory metal or smart
wire) is a metal that remembers its geometry. After it is deformed, it
regains its original geometry by itself during heating (one-way effect)
or, at higher ambient temperatures, simply during unloading
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Important Physical Effects
Piezoresistivity
Piezo electricity
Thermoelectricity
Hall-Effect
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Strain Gauge
A strain gauge is a device used
to measure deformation (strain)
of an object. The most common
type of strain gage consists of a
flexible backing which supports a
metallic foil pattern etched onto
the backing.
As the object is deformed, the
foil pattern is deformed, causing
its electrical resistance to
change. This resistance change,
usually measured using a
Wheatstone bridge circuit
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Piezo electricity
Certain classes of crystals exhibit the peculiar property of producing
an electrical field when subjected to an external force
They are attractive to MEMS because they can be used as well as
sensors as well as actuators and they can be deposited as thin film
on silicon
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Piezo electric coefficients
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Piezo electric effect
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Thermo electricity
The Seebeck effect is the conversion of heat differences directly into
electricity.
The Peltier effect is the reverse of the Seebeck effect; a creation of a
heat difference from an electric voltage
Thomson effect, describes the heating or cooling of a current-carrying
conductor with a temperature gradient. Any current-carrying conductor,
with a temperature difference between two points, will either absorb or
emit heat, depending on the material.
Seebeck is most used, in thermocouples to measure temperature
differences
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Seebeck coefficients relative to Pt
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Hall Effect
(www.sensedu.com)
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Some Sensing methods
Piezo resistive
Capacitive
Electromagnetic
Thermoelectric
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Capacitive sensing
Capacitive sensing relies on an external physical
parameter changing spacing or dielectric constant
Advantage of capacitate measurement are
(1) that it requires little energy
(2) it is relative temperature insensitive
(3) it gives the possibility to closed loop feedback
Disadvantages are
(1) Capacitive sensing requires large electronics
Measurements can be done down to pF level
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Piezo Electric actuation
Piezo Electric actuation can provide relative large forces
Thick Piezo electric films are used up to a few Newton's with a few
hundred Volts applied
Thin films ( < 5 micron) only a few milli Newton's
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Actuators
A complete paradigm change is necessary when thinking of actuating at a
micro scale. A four stroke engine is not scalable
Electrostatic Actuation
Piezo Electric Actuation
Thermal Actuation
Magnetic Actuation
Shape Memory alloys
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Thermal Actuation
Thermal actuation consumes more power than electrostatic or piezo electric
actuation. But it can provide, despite its gross inefficiencies, actuation to
hundreds of milli Newton's or higher
- Traditional bimetal
- Thermo pneumatic
- Suspended beam heating
Notice: First two methods are ambient temperature dependent
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Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
74Jan Eite Bullema
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MEMS Processes
Basic Process Tools:
Epitaxy, Oxidation, Sputter deposition, Evaporation,
Chemical Vapor Deposition
Spin-on methods, Lithography, Etching
Advanced Process Tools:
Anodic bonding, silicon fusion bonding, grinding polishing and
Electrochemical polishing, Sol-gel deposition methods
Bosch Process: DRIE
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MEMS Processes
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Epitaxy
General method to grow a crystaline layer of silicon on a
silicon wafer, with use of dopants specific properties can be
given {AsH3, PH3 (n-type), B2H6 (p-type)}
- layer thickness 1- 20 micron
- same crystaline orientation as wafer
- much used in CMOS (efficient p-n junctions)
- Temperature (> 800 °C) with SiH4, SiH2Cl2, SiCl4
- grow speeds 0,2 - 1,5 micron per minute
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Epitaxy: Silicon on Safire
So called hetero epitaxy, were two different materials are grown.
In this case Silicon on Safire (Al2O3)
Process is called SOS
Due to crystalline structure the layers of silicon on safire have to
stay thin (due to increasing defects the electrical properties of
silicon degrade)
SOS is used when optical or electrical properties require this
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Oxidation
Silicon dioxide is obtained by oxidizing silicon with dry oxygen or
steam at 850 - 1100 °C
Very well known process. Oxidation introduces compression
stress in the material because SiO2 needs more volume than
Silicon
The compression stress can be several hundreds MPa
Stress in a layer can lead to warping and curling
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Sputtering
In sputtering a target material is bombarded with inert ions (e.g. Argon
or Helium) Some material of the target is released and deposited on a
wafer
Three basic forms
- DC glow discharge
- Planar RF
- Cylindrical Magnetron or S-gun
Large range of materials: Al, Ti, Cr, Pt, Pa, Si, glass, Piezomaterial.
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Sputtering
Schematic illustration of a sputtering apparatus.
In the sputtering process, positively charged
argon ions strike the target biased negatively
and remove target atoms. These sputtered
atoms condense on the substrate to form a thin
film.
Sputtering parameters such as substrate
temperature, sputter gas pressure, target-to-
substrate distance, and target power play an
important role in the structure and composition
of deposited films.
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Sputtering
Depending on target size a good step covering can be obtained.
The film has a fine granular structure
Depending on the sputtering pressure the stress in the layer goes from
tensile (low pressures 0,1 - 1.0 Pa) to compressive (1 - 10 Pa) Good
pressure control is necessary for controlling stress
Advantage of sputtering is the relative low temperature (150 C)
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Evaporation
Local heating of target material with subsequent condensation on a
substrate. Nearly any material is suitable: Al, Si, Ti, Mo, glass, Al2O3,
etc
Inclusive refractory materials: W, Au, Cr, Pd, Pt as long as the vapor
pressure is higher than the background pressure
Important is that the carrier (mostly W) does not evaporate
Stress in the layer can become very large (depending on the
temperature) in W up to 500 MPa
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Thermal Evaporation
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Chemical Vapour Deposition
Chemical Vapour Deposition is mostly a process at elevated
temperatures (> 300 °C)
Materials that can be deposited are:
- silicon,
- poly silicon
- amorf silicon
- SiO2
- Si3N4
- Cu and low r material
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Common CVD Deposition Chemistries
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Chemical Vapour Deposition
There two important forms of CVD:
- Low pressure Chemical Vapour Deposition (LPCVD)
- Plasma Enhanced Chemical Vapour Deposition (PECVD)
LPCVD temperatures > 800 °C
PECVD temperatures ~ 300 °C
Many layer properties can be controlled with deposition parameters
(pressure, temperature, gas flow, dopants, power and plasma
excitation)
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Example PE- CVD Equipment
The Plasma Enhanced Chemical Vapor
Deposition (PECVD) machine is used to
deposit thin dielectric films. It combines up
to four gases at pressures between
0.1 and 1 Torr and uses an RF source
of up to 200 Watts to ionize the resultant
gas mixture, causing film deposition on
a heated substrate.
Films deposited with the system include:
SiO2, SiOxNy, and Si3N4.
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Polysilicon with CVD
Polysilicon deposition on a wafer can be done from tens of nm to
several microns thickness on a silicon wafer
Easy to apply by pyrolysis of Silane (SiH4) with LPCVD at 550 - 750
°C. PECVD is also possible.
Depending on process conditions amorphous or crystalline silicon is
obtained.
Good step covering
Stress can be reduced by annealing > 900 °C
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Silicon dioxide with CVD
Silane and oxygen in a CVD reactor result in on SiO2 layer
Boron and or phosphorus can be build in to obtain specific properties.
E.g. Low Temperature Oxide (LTO) which can be used to obtain an
excellent step coverage of the SiO2 layer by heating to 1000 °C
Silicon oxide also can be obtained by pyrolysis of [Si(OC2H5)4]
TEOS (tetra ethoxy silane) in LPCVD at 650 - 700 °C
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Silicon Nitride with CVD
Silicon nitride is good for passivation and an excellent barrier for water
and sodium ions. For MEMS it is an excellent mask for etching with
KOH
Stoichiometric Si3N4 is obtained by atmospheric CVD of SiH4 and NH3
or SiCl2H2 and NH3 at 700 - 900 °C
H2 is absorbed in the layer which lead too large tensile stresses
(e.g. 1000 MPa)
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Spin on methods
With spin on methods layers of dielectric insulators and organic
materials can be applied
A table spins with typical 500 - 5000 rpm
Thicknesses are 0,5 - 20 micron
For SU-8 epoxy it can be 1 up to 1000 micron
Glasses also can be applied
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Lithography
Lithography has three essential steps:
- application of photoresist with a photosensitive emulsion layer
- optical exposure to print an image of the mask into the resist
- immersion in an aqueous development solution to dissolve exposed
resist and render visible the latent image
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Lithography
There are three main forms of lithography
- Contact
- Proximity
- Projection
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Lithography
Resolution:
- contact 1 - 2 micron
- proximity 5 micron (Fresnel limitation)
- projection (better than 1 micron)
Depth of Focus is sometimes limiting for thicker structures
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Comparison Wet and Dry Etching
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Example Lithography Equipment
The Canon Parallel Light Mask Aligner
is a machine used in the process of
lithography. The shown machine allows
for the use of 4-5 inch photomasks
and can handle 2-5 inch wafers.
Both the mask and wafer can be brought
into sharp focus, facilitating the proper
alignment of mask and wafer for
maximum exposure accuracy.
.The maximum print diameter is 5 inches, which is a relatively large exposure area.
As such, the number of devices per wafer and throughput is increased. This Canon
Aligner is also equipped with an auto feeder, allowing hands-off loading and
unloading of the wafer
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Double Sided Lithography
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Thick resist
With multiple spin on process a thick resist layer can be obtained.
Due to height differences (topological height variations) some
processes become very difficult.
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Etching
Etching processes in MEMS are derived from traditional etch processes
for semiconductor processes.
‘Underpinning is in science, much remains an art’
The objective is to selectively remove material using imaged
photoresist as a masking template.
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Etchants of Silicon
102
Isotropic and Anisotropic Etching
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Anisotropic Etching
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Anisotropic Etching: Suspended beam
105
Etchants of Thin Metal Films and Insulators
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Deep Reactive Ion Etching (Bosch Process)
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Deep Reactive Ion Etching (Bosch Process)
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Deep Reactive Ion Etching (Bosch Process)
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109
Isotropic wet Etching
Common wet etchant is HNA also known as poly etch
H = Hydrofluoric Acid (HF)
N = Nitric Acid (HNO3)
A = Acetic Acid (CH3COOH)
Nitric acid oxidizes silicon which is removed by HF
Etch depth and surface condition are mostly difficult to control (Etch
rate up to 20 micron)
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Anisotropic wet etching
Anisotropic wet etchants include the hydroxides of alkali metals (KOH,
NaOH, CsOH, etc), simple and quaternary ammonium hydroxides
(NH4OH, (CH3)4NOH)
Potassium hydroxide is the most common
KOH etches the {111} planes 100 times faster than the {100} planes.
This feature is routinely used to make V shaped grooves that are
precisely delineated by the {111} crystallographic planes
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Anodic bonding
Bonding of silicon and sodium containing glass (Pyrex 7740 and 7070
or Schott 8330 and 8329) It is fundamental to manufacture of a wide
variety of sensors, including pressure sensors, because it provides a
rigid support in the form of a glass substrate rather than the fragile
silicon
bonding at 200 - 500 °C in vacuum, air or inert
application of a voltage 500 - 1500 V across the two substrates
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Anodic bonding
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Silicon fusion bonding
Silicon fusion bonding, also known as direct wafer bonding is a process
capable of securely joining two silicon substrates
The bonding mechanism is not well understood but it is widely believed
that it occurs at a molecular level.
Formation of OH groups on the surface and cleanliness are important.
A temperature anneal at 800 - 1000 °C promotes and strengthen the
bond reaction
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LIGA (LIthography, Galvanie, Abformung)
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SU-8 Process
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SU-8 Epoxy
SU-8 Epoxy Structures
Examples of SU-8 epoxy structures that are available as foundry
processes. Structure heights from 1 micron to 1 millimeter are possible
and side-wall angle can also be controlled for various geometries.
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Process Flow
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Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
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MEMS Products
Pressure Sensor
Accelerometer
Mass Flow Sensors
Digital Micro mirror Device
Angular Rate Sensors
Fluid Nozzles, inkjet print nozzles, micro filtration
Micro machined valves
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Relative Merits different sensing principles
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Pressure sensor
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Fabrication steps for a piezoresistive gauge
Pressure sensor
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Pressure sensor
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Pressure sensor
Fabrication process of a SOI high-temperature pressure sensor.
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Pressure sensor
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Pressure sensor
The machined silicon-structure is protected in an elektronics package
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Nano Probe
Beams of the Silicon part
are 20 – 30 m thick, the
function of the nano probe
requires thin beams
For assembly thin beams
are challenging
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Flow Sensor
Gas flow cools the upstream heater and heats the downstream heater.
Temperature-sensitive resistors are used to measure the temperature of each
heater and consequently infer the flow rate. The etched pit underneath the
heater provides exceptional thermal isolation to the silicon support frame.
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Accelerometer
Acceleration
(1) Front and side airbag crash sensing (2) Electrically controlled car
suspension. (3) Safety belt pretensioning . (3) Vehicle and traction control
systems. (4) Inertial measurement, (5) object positioning, and navigation
(6) Human activity for pacemaker control
Vibration
(1) Engine management (2) Condition-based maintenance of engines
and machinery (3) Security device (4) Shock and impact monitoring
(5) Monitoring of seismic activity
Angles of inclination
(1) Inclinometers and tilt sensing (2) Vehicle stability and roll (3) Computer
peripherals (e.g., joystick,head mounted displays … ) (4) Handwriting recognition
(e.g., SmartQuill from British Telecom) (5) Bridges, ramps, and construction
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Acclerometer: Principle
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Differences in G measurements
Airbag 50 G Bandwidth 1 k Hz
Motor sensor: 1 G resolution 100 micro G Bandwidth > 10 kHz
Hart sensor: 2 G Bandwidth 50 Hz
ultra low power consumption
Military sensor: 1000 G
Drop test: 10 000 G
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Accelerometer
Illustration of a piezoresistive accelerometer from Endevco Corporation fabricated
using anisotropic etching in {110} wafers. The middle core contains the inertial
mass suspended from a hinge. Two piezoresistive sense elements measure the
deflection of the mass. The axis of sensitivity is in the plane of the middle core.
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Bulk micro machined PZR sensor
Proof mass typical 100 micro grams
PZR (Boron doped Silicon) 0,6 micro thick 3,4 micron broad
Signal in Wheatstone bridge typical 1 G / 25 mV over 10 V
Measurement until 6000 G
Shock proof 10000 G
Bandwidth 28 k Hz
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Accelerometer
Capacitive bulk-micromachined accelerometer. The inertial mass in the middle
wafer forms the movable electrode of a variable differential capacitive circuit.
Adapted from the accelerometer product catalog
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Accelerometer
Process steps to fabricate the middle wafer containing the hinge and the
inertial mass of a capacitive bulk-micromachined accelerometer
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Bulk Micro Machined Capacitive Sensor
Proof mass typical 100 micro grams
Capicitance translated to + - 2,5 V
Measurement 1.5 to 50 G
Shock proof 20000 G
Bandwidth 400 Hz
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Accelerometer
Basic structure of the ADXL family of surface- micromachined accelerometers.
A comb-like structure suspended from springs forms the inertial mass.
Displacements of the mass are measured capacitively with respect to two
sets of stationary finger-like electrodes.
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Surface Micro Machined Capacitive Sensor
Proof mass typical 0.3 to 1 micro grams
Total capacitance 100 f F (f = femto = 10-15)
Measurement 100 aF (a = atto = 10-18)
100 aF equals circa 625 electrons
no parasitic currents are allowed all signal processing on the sensor
Measurement typical airbag 1 - 50 G
Price current below 3 USD per product (Bosch and Analog Devices)
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Accelerometer
Photograph of a deep-reactive-ion-etched (DRIE) accelerometer using
60-mm-thick comb structures.
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DRIE Capacitive Sensor
Proof mass typical 43 micro grams
Total capicitance 3 pF (p = pico = 10-12)
Thermal Noise: 10 G /  Hz
Compared to surface micro machined sensor
Thermal Noise: 500 G /  Hz
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Accelerometers
Commercial accelerometers only cost a few Euros
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Angular-rate sensor
A conventional mechanical gyroscope and the three rotational degrees of
freedom it can measure.
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Angular-rate sensor
The Coriolis acceleration on an object moving with a velocity vector v on the
surface of Earth from either pole towards the equator. The Coriolis acceleration
deflects the object in a counterclockwise manner in the northern hemisphere
and a clockwise direction in the southern hemisphere. The vector  represents
the rotation of the planet.
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Angular-rate sensor
Tuning fork structure for angular-rate sensing. The Coriolis effect transfers
energy from a primary, flexural mode to a secondary, torsional mode.
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Angular-rate sensor
The corresponding standing wave pattern
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Angular-rate sensor
Angular-rate sensor. The basic structure consists of a ring shell suspended
from an anchor by support flexures. A total of 32 electrodes (only a few are
shown) distributed around the entire perimeter of the ring excite a primary mode
of resonance using electrostatic actuation. A second set of distributed
electrodes capacitively sense the vibration modes. The angular shift of the
standing wave pattern is a measure of the angular velocity.
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Angular-rate sensor
VSG angular-rate sensor from British Aerospace Systems and Equipment, and
corresponding fabrication process. The device uses a vibratory ring shell design,
similar to the Delco sensor. Eight current loops in a magnetic field, B, provide the
excitation and sense functions. For simplicity, only one of the current loops is
shown.
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Angular-rate sensor
Angular-rate sensor from Daimler Benz. The structure is a strict implementation
of a tuning fork in silicon. A piezoelectric actuator excites the fork into resonance.
The Coriolis force results in torsional shear stress in the stem which is measured
by a piezoresistive sense element.
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Angular-rate sensor
The main fabrication steps for the Daimler Benz micromachined angular-rate
sensor.
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Carbon monoxide sensor
Carbon monoxide sensor, its equivalent circuit model, and the final packaged
part. The surface resistance of tin-oxide changes in response to carbon
monoxide. A polysilicon heater maintains the sensor at a temperature between
100 and 450º C in order to reduce the adverse effects of humidity.
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DMD™
Single DMD™ pixel in its resting and actuated states. The basic structure
consists of a bottom aluminum layer containing electrodes, a middle aluminum
layer containing a yoke suspended by two torsional hinges, and a top reflective
aluminum mirror. An applied electrostatic voltage on a bias-electrode deflects
the yoke and the mirror towards that electrode. A pixel is 17 m on a side.
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DMD™
Optical beam-steering using the switching of micromirrors. Off-axis illumination
reflects into the pupil of the projection lens only when the micromirror is tilted in
its +10º-state, giving the pixel a bright appearance. In the other two states, the
pixel appears dark
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DMD™
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DMD™
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DMD™
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Grating Light Valve
Operating principle of a single pixel in the grating light valve. Electrostatic pull-
down of alternate ribbons changes the optical properties of the surface from
reflective to diffractive.
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Passive structures
Nozzles are the most simple passive structure
Patents for IBM In the 1970s for silicon nozzles for ink jet application
Patents for Ford in the 1980s for motor fuel injection applications
Nowadays these patents are expired. Many new research in the field of
medical inhalers, atomizers, fluid spray systems
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Passive structure
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Passive structures
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Inkjet
Cross-sectional illustration of a thermal inkjet head and the ink firing sequence.
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Inkjet
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Various actuation methods
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Micro Valves
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Micro Valves
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Development of Microfluidic Interconnection
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Areas of Expertise 172
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
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Wireless EEG Measurement
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Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
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Medical Applications of Micro and Nano
Technology
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‘It would be interesting in surgery
if you could swallow the surgeon’
Richard P. Feynman
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Pacemaker
The pacemaker is one of the oldest examples of a MST product
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Pacemaker Historic Developments (1950)
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Pacemaker Historic Developments (2000s)
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Pacemaker ( Integration of Functions)
Integration of Functions
In the pacemaker by:
- MEMS Accelerometer
- Digital control
- Remote diagnostics
- use of MEMS switches
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jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Pacemaker Decreasing Dimensions
MEDTRONIC, is using micro electronics
and chip manufacturing to shrink pacemakers
– implanted devices that regulate the hearts
rhythm. Whereas current pacemakers are
the size of a silver dollar. Medtronics new
device would be smaller than a tic-tac.
At that size the pacemaker could be inserted
through a catheter rather than invasive surgery
http://www.technologyreview.com/biomedicine/32436
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Implantable wireless pressure sensor
CardioMEMs’ device measures blood pressure in people who have an
abdominal aortic aneurysm. Doctors can treat the bulging artery with a
stent graft, stents can fail, aneurysm patients require lifetime monitoring
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jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Implantable wireless pressure sensor
184
jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technolo
Stents
185
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Hearing Aid
Trend is that products become
smaller
and
smarter
This is enabled by developments
In micro electronics and in micro
systems technology
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Type Typical cost
Euro per unit
Behind the ear 200 - 300
In the ear 500 - 700
In the canal 700 - 1000
Completely
in the canal 1400 - 2000
Cochlear Implants 35000 - 50000
Hearing Aids & Cochlear implants
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Hearing Aids
Source: Phonak
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Cochlear Implants
1985 1991 1997 1999 2000 2004
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jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Flexible Solar Retinal Implants
Age related Macular
Degeneration (AMD)
Affects about 1,5 Million
people per year in the US
and is the most prevalent
cause for blindness in the US
jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Flexible Solar Retinal Implants
jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Flexible Solar Retinal Implants
Retinal Implant
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jan_eite.bullema@tno.nl
Medical Applications of Micro and
Nano Technology
Eye pressure measurement
in glaucoma patients
In the eye pressure sensor
- a pressure sensor
- a low-power microprocessor
- a solar cell
- a wireless radio
- memory
- and a thin film battery.
http://techknowbits.com
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Endoscope
Source: PENTAX FG-32UA
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Smart pill
This smart-pill (M2A capsule) contains
a number of the functions that a
microsystem can have:
- The pill can observe with a camera
- The pill has a processor to process
signals to information
-The pill has coil to transmit information
- The pill has a battery for energy
supply purposes
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Properties of the smart pill
The capsule is 11mm x 26mm (<4 grams)
Field of view is 140 degrees.
Detection of objects at a minimum size
less than 0.1 mm
In a normal (8 hr) procedure the
generates approximately 57,000 images,
at a rate of two frames / second.
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Capsule Endoscopy Image
Eosinophilic Enteritis
visualizing folds
of the cecum
Cecum Nematodes
Pinworm in
healthy volunteer
Note thickened...
Kaposi’s Sarcoma
cutaneous Kaposi’s
Normal ColonHemorrhagic
60 year old woman Normal vessels
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Billicheck improves comfort
Not a heel puncture but an optical measurement
The analysis is done with a plastic grating
The grating is made with LIGA technology
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Optical Diagnosis with MST components
Source: Micro Parts
Color Check of Teeth Bili Check for Jaundice
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Drug Delivery Pill: iPill by Philips
Philips has developed
a drug delivery pill
(2.6 x 1.1 Ø cm)
30% is drug container
It measures pH and
temperature and can
deliver drugs on site
IMAPS iPill for controlled drug delivery – Frits Dijksman, November 20-th 3-rd, 2008
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Drug Delivery Pill: iPill by Philips
Length small intestines 4-6 m
Drift velocity (due to peristalsis) in small
intestines 1 m/h
Residence time in small intestines 4-5
hrs
Length large intestines 1-1.5 m
Throughput time1-5 days
202
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Drug Delivery Pill: iPill by Philips
203
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Drug Delivery Pill: iPill by Philips
• Crohn’s Disease and Ulcerative
Colitis
• Chronic autoimmune disease of
• unknown etiology
• Prevalence: ~1.4M in U.S., similar in
Europe
• High patient burden and cost to
society
• Significant unmet needs in diagnosis,
treatments, and disease management
204
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Drug Delivery Pill: iPill by Philips
• Dimensions length 26 mm, diameter 11 mm
• Weight 3.2 gr (specific mass 1450 kg/m3)
• Medication content 300 micro liter
• Minimum dispensed volume 1 micro liter
• Once per 20 seconds the status on temperature, pH, medication
content, battery will be transmitted to the outside of the body
• Reach RF link 0.3 m in the body
205
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Drug Delivery Pill
Diagnostic Therapeutic
Non-invasive Non Invasive
Miniaturized Miniaturized
Patient Comfort Intelligent Device
Ease of Use Individual Therapy
High Data Content Disease Management
Faster Health Monitoring
Cheaper Compliance Monitoring
206
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Permanent medication dosing
The artificial pancreas gives the diabetic patient a continuous
and correct dosing of insulin
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Insulin Dispenser
Debiotech’s Insulin Nanopump
Each pump actuation injects only 200
nanoliters of drug,and reproducibility is
better than 2%, bringing it very close
to physiological delivery of insulin.
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Aerosol dispenser
By the micro holes an aerosol can be dispensed with
droplets of a very well defined droplet diameter
(droplets of circa 1 micron diameter)
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Aerosol dispenser
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Catheters for key-hole surgery
A surgical doctor inspects a pressure sensor before he
Starts measuring the pressure in the heart of the patient
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Catheters for brain measurements
Length: 340 mm
Diameter: 0,6 mm
Electrodes: 31 + 1
Array length: ca. 6 mm
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Neuroprobes for brain probing
2mm shank length: 112 electrodes
8 mm shank length: 512 electrodes
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Full 3D array for brain probing
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Microfluidics: Market
World Market Microfluidics (MST News Feb 2008)
2004 2009 (prognosis)
Volume 630 M USD 1500 M USD
Microfluidic Chips 65% 67%
Pressure Sensors 23% 13%
Drug Delivery 1% 13%
IR Sensors 5% 3%
Micro Spectrometers 3% 2%
Other 2% 3%
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Lab-on-a-chip (micro array)
By capillary action the sample is pulled to the reactive spots
Small sample volume + large number of analysis simultaneously
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Microfluidics: Overview
One important manner in which microfluidics differs from micro
electronics. Is that the fundamental physics changes more rapidly as
the size scale is decreased
Micro fluidics quickly reach length scales were fundamental fluid
physics change dramatically.
E.g.
Reynolds (Re) = inertial / viscous = . U0 .L0 / 
Péclet (Pe) = convection / diffusion = U0 . L0 / D
Capillary (Ca) = viscous / interfacial =  . U0 / 
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Micro fluidics: Reynolds (viscous / interfacial)
Reynolds (Re) = inertial / viscous = . U0 .L0 / 
Flow in micro channels has typically Re 10 -6 to 10
{ water (1 mPa.s, diameter (L0) 1 – 100 mm, flow (U0) 1m/s to 1cm/s }
Flow in micro channels is always laminair as
viscous forces >> inertial forces
Spermatozoa ~ 1×10 −2
Blood flow in brain ~ 1×102
Blood flow in aorta ~ 1×103
Onset of turbulent flow ~ 2.3×103
Person swimming ~ 4×106
Aircraft ~ 1×107
Blue whale ~ 3×108
A large ship (RMS Queen Elizabeth 2) ~ 5×109
Jan Eite Bullema 218
Jan Eite Bullema 219
Microchannels in Plastics
Micro channels are used more and more in ‘Lab on a Chip’ products
The example is a capillary with a width of 100 micron
Jan Eite Bullema 219
Jan Eite Bullema 220
Lab-on-a-Disk
The Gyros device uses a passive valve principle. Some parts of the
micro-channels have hydrophobic properties. These will act as a closed
valve, fluid can not pass due to the hydrophobic surface. As the device
is rotated, centrifugal forces will overcome the hydrophobic forces and
pass the hydrophobic valve region.
Gyros: Lab-on-a-Disk
Jan Eite Bullema 220
Jan Eite Bullema 221
Legionella detection
Jan Eite Bullema 221
Jan Eite Bullema 222
Smart Diagnostics for Healthcare
Sample
Biopsy
Filtering /
Concentrating
Lysis /
Extract DNA
Seperating
DNA / Rest
PCR
Washing /
Filtering
DNA
detection
Sample preparation and analysis on a 1’ x 3’ (25 x 75 mm) lab-on-a-chip
Washing
1 2 3 4
4 65 7
Jan Eite Bullema 222
Jan Eite Bullema 223
Genome Size
FERN 160,000,000,000
LUNGFISH 139,000,000,000
SALAMANDER 81,300,000,000
NEWT 20,600,000,000
ONION 18,000,000,000
GORILLA 3,523,200,000
MOUSE 3,454,200,000
HUMAN 3,400,000,000 31,000
Drosophila 137,000,000 13,500
C. Elegans 96,000,000 19,000
Yeast 12,000,000 6,315
E. Coli 5,000,000 5,361
smallest Genome ??????
genes
Jan Eite Bullema 223
Jan Eite Bullema 224
Cells
Humans
60 trillion (1012) cells
320 cell types
Jan Eite Bullema 224
Jan Eite Bullema 225
Jan Eite Bullema 225
The original Watson and Crick’s paper
Jan Eite Bullema 226
The central dogma of molecular biology
DNA RNA proteintranscription translation
Jan Eite Bullema 226
Jan Eite Bullema 227
PCR = Polymerase Chain Reaction
Jan Eite Bullema 227
Jan Eite Bullema 228
Silicon PCR chamber
Jan Eite Bullema 228
Jan Eite Bullema 229
Capillary Electrophoresis
Jan Eite Bullema 229
230Jan Eite Bullema
Capillary Electrophoresis
231Jan Eite Bullema
Capillary Electrophoresis
Jan Eite Bullema 232
Capillary Electrophoresis
Jan Eite Bullema 232
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
233Jan Eite Bullema
Jan Eite Bullema 234
Packaging of MEMS
Packaging of MEMS converts a machined structure into a useful
assembly that can safely and reliable interact with its environment
Definition of MEMS packaging is broad because each application is
unique in its packaging requirements
Function =
Protect the micro machined structure to a broadening range of
environments. It must also provide interconnections toelectrical signals,
electrical interconnect, access to environment and interaction with
environment
Jan Eite Bullema 234
Jan Eite Bullema 235
Packaging Hierarchy
(level of packaging)
Jan Eite Bullema 235
Jan Eite Bullema 236
Package Functions
- Power distribution
- Signal distribution
- Heat dissipation
- Protection
- Manufacturability /
Processing of
Components
Jan Eite Bullema 236
Jan Eite Bullema 237
Typical MEMS packaging process flow
Jan Eite Bullema 237
Jan Eite Bullema 238
Saw and Dice wafer
In a FAB thousands of micro structures are made simultaneously.
Dicing separates the structures into individual components
Most common is a diamond saw with 75 - 250 micron thick
blades, The wafer is held by a blue colored sticky tape and
the wafer is cooled continuously
Potential damaging of the structure during the process
Sometimes the last sacrificial etching is done after dicing
Jan Eite Bullema 238
Jan Eite Bullema 239
Process Flow Wire Bonding
Jan Eite Bullema 239
Jan Eite Bullema 240
Characteristics Flip Chip Bonding
Flip Chip implies bonding the die face down. Electrical contacts are
made by means of plated bumps between bond pads on the die and
metal pads on the package substrate. The attachment is intimate with
small spaces (50 - 200 micron) between the die and the package. The
pads can be all over the surface of the die (area arrays) resulting in an
increase in density of (I/Os)
Inductance of a solder bump
is less than 0.05 nH compared
to 1 nH for a 125 micron long
and 25 micro thick wire bond
Jan Eite Bullema 240
Jan Eite Bullema 242
Thermal Condsiderations
More complex chips make more demands on efficient heat removal
from the chips.
Silicon chips limited to approximately 100ºC for normal operation
which limits power densities on chip to a maximum of 10watts/cm2
in current IC packages.
Imposes a limit average on power dissipation per individual circuit
on chip of approximately 1µW/circuit for a 10 million transistor chip
of area 1cm × 1 cm.
Jan Eite Bullema 242
Jan Eite Bullema 243
Thermomechanical Considerations
Important to reduce power dissipation/circuit and improve package
thermal design in order to produce larger, more complex ICs in the
future.
Differential thermal expansion of package parts gives rise to
mechanical stresses and reliability risks.
E.g. Coffin Manson behaviour
# cycles before failure = Function ( thickness / T *  CTE)
Jan Eite Bullema 243
Jan Eite Bullema 244
Package Sealing and Encapsulation
Intended to protect the chip and package metallisation from corroding
environments and from mechanical damage due to handling.
Moisture is one of the major sources of corrosion.
Plastic materials, such as silicones and epoxies, developed with low water
diffusion properties are used extensively for IC encapsulation.
For high reliability devices hermetic sealing used based on welding or brazing
of ceramic/metal packages. More expensive and time-consuming than plastic
encapsulation
Jan Eite Bullema 244
Jan Eite Bullema 245
Protective coating and media isolation
Coatings are often used in flow sensors and pressure sensors.
- in cars salt water sprays, acid rain polutants can attack the sensor
- home applyances oftengive alkaline environments
An often used coating is parylene ( p-xylylene) which can
be deposited at room temperature and gives a conformal
coating resistant to: exhaust gasses, fuel, salt spray,
water, alcohol, organic solvents.
Strong acids and bases dissolve parylene
Jan Eite Bullema 245
246Jan Eite Bullema
Thermal Shock
Thermal
Humidity
Corrosive
Dust
Vibration
Power Cycling
Voltage Margining
Frequency Margining
Relative Causes for Failure in Electronics
Jan Eite Bullema 247
Characteristics of Ceramic Packaging
Ceramics are hard and brittle materials made by shaping a nonmetalic
mineral, then firing at high temperatures for densification. Most
ceramics are electrical insulators and good thermal conductors
Jan Eite Bullema 247
Jan Eite Bullema 248
Process Flow Ceramic Package
Jan Eite Bullema 248
Jan Eite Bullema 249
Ceramic Packaging of DMD
The DMD package is a ceramic package.
A DMD sells for several hundred dollars.
An accelerometer packaged in ceramic would cost 35 USD, a plastic
packaged accelerometer only 2-4USD
Jan Eite Bullema 249
Jan Eite Bullema 250
Capping
Jan Eite Bullema 250
251Jan Eite Bullema
Thin Film Capping
Jan Eite Bullema 252
Metal Package
Metal packages are attractive for MEMS because they can be
prototyped in small series and are hermetic. Disadvantage is the
high costs relative to plastic
Jan Eite Bullema 252
253Jan Eite Bullema
Plastic Packaging
254Jan Eite Bullema
Ceramic Package
255Jan Eite Bullema
Optical Package
Jan Eite Bullema 256
Molded plastic packaging
Post molded: plastic is molded after the die is attached to a lead
frame (process subject die and interconnect to harsh molding
conditions)
A major disadvantage of plastic
packages is hat they are not
hermetic
Yet in traditional electronics plastic
packages are prefered:
low cost few pennies per pin
high reliability: one failure
per billion hours operating time
Jan Eite Bullema 256
Jan Eite Bulema 257
Plastic Cap for MEMS
Feasibility of polymers for wafer scale packaging of RF MEMS
P.J. Bolt, J.E. Bullema, R. Korbee, 4M, Cardiff 2008
Jan Eite Bullema 257
Jan Eite Bullema 258
3D - Packaging
3D Technology according to Suss
Jan Eite Bullema 258
Jan Eite Bullema 259
3D - Packaging
(e.g. MEMS Scale Package)
J.E. Bullema, M.H.M. Meuwissen, E.P. Veninga, " Design Study for Stacked MEMS",
Proceedings Eurosime 2003, Key note Paper, 30 March - 2 April 2003, p279..283,
Jan Eite Bullema 259
Jan Eite Bullema 260
3D - Packaging
Typical System in Package in 2010 [Wolf,2007]
Jan Eite Bullema 260
261Jan Eite Bullema
Tire Pressure Sensor
(FHG – IZM)
262Jan Eite Bullema
TX on micro processor
(FHG – IZM)
263Jan Eite Bullema
RF sensor with TSV
(Omron)
264Jan Eite Bullema
RF sensor with TSV
(Omron)
265Jan Eite Bullema
Future MEMS Packaging with TSV
Build Up of the Micro- and
Nanotechnology course
Introduction
History, markets, expectations
Materials for micro and nano
Processes and technologies
Micro and nano products
Converging technologies: MNBT
Medical applications
Packaging
Wrap-up / multiple choice test
266Jan Eite Bullema
Jan Eite Bullema 267
Wrap - Up
Some Collective Multiple Choise
A typical proof mass of an accelerometer is in the range of:
A 10 micro gram to 100 micro gram
B 100 micro gram to 1 milligram
C 1 micro gram to 100 micro gram
D 0,1 micro gram to 100 micro gram
Jan Eite Bullema 267

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2011 Introduction micro and nanotechnology

  • 1. Jan Eite Bullema version 2011 Introduction Micro- and Nano Technolgy
  • 2. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 2Jan Eite Bullema
  • 3. Reference Books Reader: Introduction Micro- and Nano Technology, J.E. Bullema Further reading: An Introduction to Micro Electro Mechanical Systems Engineering, Nadim Maluf, ISBN 0-89006-581-0, 2004 Comprehensive Microsystems, Yogesh B.Gianchandani , 2007 Fundamentals of Micro System Packaging, Rao Tummala, 2001 Micro and Nanomanufacturing, Mark Jackson, 2010 Micro Systems Technology, Wolfgang Menz, 2001 Nano-Bio- Electronic, Photonic and MEMS Packaging, C.P. Wong 2010 3Jan Eite Bullema
  • 4. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 4Jan Eite Bullema
  • 5. Definition of Micro Systems Technology MEMS/ Micro Systems Technology is simultaneously a toolbox, a physical product, and a methodology, all in one: • It is a portfolio of techniques and processes to design and create miniature systems. • It is a physical product often specialized and unique to a final application one can seldom buy a generic MEMS / MST product at the neighborhood electronics store. • “MEMS / MST is a way of making things,” reports the Microsystems Technology Office of the United States DARPA. These “things” merge the functions of sensing and actuation with computation and communication to locally control physical parameters at the microscale, yet cause effects at much grander scales. 5Jan Eite Bullema
  • 6. Definition of Nanotechnology The U.S. National Nanotechnology Initiative gives the following defining features of nanotechnology: 1. Nanotechnology involves research and technology development at the 1nm-to-100nm range. 2. Nanotechnology creates and uses structures that have novel properties because of their small size. 3. Nanotechnology builds on the ability to control or manipulate at the atomic scale. 6Jan Eite Bullema
  • 7. The Micro and Nano meter domain 7Jan Eite Bullema Hair Flake EggLouse Diode Solder- line Digital Mirror Transistor IC line (157 nm)) Pore 1 mm 0,1mm 0,01mm 1mu 0,1mu Atom (Co on Pt) Back Finger Nail Bacteria DNA PCB ICTelevision Quantum structure Buckey Ball Semen 1m 0,1m 0,01mu 1nm 0,1nm0,01m BIOLOGICAL Scale TECHNOLOGICAL Scale
  • 8. History Micro and Nano Technology: Feynman The origin of the concept of micro and nano technology is the speech ‘There is plenty of room at the bottom’ given by Richard Feynman for the American Society of Physics on December 29, 1959. Feynman argued in his lecture that one would be able to do amazing things by decreasing the size. • Why cannot we write the entire 24 volumes of the Encyclopedia Brittanica on the head of a pin? • He also presented the "weird possibility" of "swallowing the doctor" This concept involved building a tiny, swallowable surgical robot by developing a set of one-quarter-scale manipulator hands slaved to the operator's hands to build one-quarter scale machine tools analogous to those found in any machine shop. 8Jan Eite Bullema
  • 9. History Micro and Nano Technology: Taniguchi "‘Nano-technology’ mainly consists of the processing of separation, consolidation, and deformation of materials by one atom or one molecule." 9Jan Eite Bullema
  • 10. History Micro and Nano Technology: Drexler Eric Drexler, a student of Feynman, wrote in 1986, Engines of Creation: The Coming Era of Nanotechnology. Describing self-replicating nano- assemblers building objects one atom at a time. 10Jan Eite Bullema
  • 11. History MNT: Binning and Rohrer Binnig and Rohrer at IBM Zurich invented the scanning tunneling microscope (STM) the first instrument to generate real-space images of surfaces with atomic resolution. This discovery opened up the important new field of nanotechnology and was recognized by the 1986 Nobel Prize in Physics. Subsequently, the atomic force microscope (AFM) was developed. STM and AFM enabled not only the imaging of individual atoms, but also the manipulation of a single atom. 11Jan Eite Bullema
  • 12. History Micro and Nano Technology: Smalley Richard Smalley, is one of the scientists that is credited with discovering buckyballs. Smalley and his co-workers, produced the buckyballs in a device by vaporizing carbon with a laser and allowing the carbon atoms to condense. 12Jan Eite Bullema
  • 13. History Micro and Nano Technology: Geim Andre Geim and Konstatin Novoselov discovered graphene. Graphene is a 2D mono layer of carbon, with remarkable physical properties. Extreme mechanical strength, optical transparent, hermetic, excellent electrical conduction. Graphene is already produced in industrial quantities for display applications. As graphene is electrical conductive and transparent (98% per carbon layer) 13Jan Eite Bullema
  • 14. Market Expectations: Perspective 2010 Estimates: World Total Business ~ 55,000 Billion USD Electronics Market ~ 1,000 Billion USD GDP the Netherlands ~ 650 Billion USD Semiconductor Market ~ 350 Billion USD PhotoVoltaic Market ~ 40 Billion USD Turnover Philips Electronics ~ 33 Billion USD MEMS/MST Market ~ 7 Billion USD Turnover ASML ~ 5,4 Billion USD Nano Materials Composites ~ 0,5 Billion USD 14Jan Eite Bullema
  • 15. Market Expectations: MEMS / MST Market (Source PCB May 2011) 15Jan Eite Bullema Sales M$ MEMS family Major Market Texas Instruments Hewlett Packard Robert Bosch STM Microelectronics Panasonic Seiko Epson Canon Denso Freescale Semicond. Avago Technologies 856 807 637 600 376 305 293 265 240 226 Electro Optic Electro Fluidic Electro Mech. Electro Mech. Electro Fluidic Electro Fluidic Electro Fluidic Electro Mech. Electro Mech. Various Projection / mobile Ink jet printer cartridge Airbag accelerometer Airbag / Game acceler. Ink jet printer cartridge Ink jet printer cartridge Ink jet printer cartridge Airbag Accelerometer Airbag Accelerometer Various 1. Ink jet cartridges, almost $2B 2. Airbag and gaming accelerometer, $1.8B 3. Projection, over $800M
  • 16. Market Expectations: MEMS / MST Market (Source Yole August 2011) 16Jan Eite Bullema Sales M$ MEMS family Major Market Texas Instruments Hewlett Packard Robert Bosch STM Microelectronics Panasonic Seiko Epson Canon Denso Freescale Semicond. Avago Technologies 856 807 637 600 376 305 293 265 240 226 Electro Optic Electro Fluidic Electro Mech. Electro Mech. Electro Fluidic Electro Fluidic Electro Fluidic Electro Mech. Electro Mech. Various Projection / mobile Ink jet printer cartridge Airbag accelerometer Airbag / Game acceler. Ink jet printer cartridge Ink jet printer cartridge Ink jet printer cartridge Airbag Accelerometer Airbag Accelerometer Various 1. Ink jet cartridges, almost $2B 2. Airbag and gaming accelerometer, $1.8B 3. Projection, over $800M
  • 17. MEMS and Sensors in Mobile Phones (Source Yole August 2011 17Jan Eite Bullema
  • 18. Market Expectations: Medical MNT Devices The total market for Medical Devices is estimated as follows: Drugs and drug delivery 80 B USD Blood Analyis 22 B USD Heart Pacemakers & other implants 16 B USD Endoscopes and MIS tools 5 B USD Hearing Aids 4 B USD DNA & Lab on a Chip 1,2 B USD Micro and Nano Technology based Products accounts for an estimated 7 B USD, components account for 326 M USD. www.tft-ltd.co.uk 18Jan Eite Bullema
  • 19. Market Expectations: Dutch MNT Companies Company Product / Service Aquamarijn Micro sieves ASMI Various equipment ASML Wafer stepper Bronkhorst High Tech Flowsensors C2V / Thermo fisher micro Gas chromatography Cavendish Kinetics Non volatile memory Cytocentrics Patch Clamping Chemtrix Process intensification EPCOS RF Switches Fei Company Electron microscopy Fluxxion Micro sieves 19Jan Eite Bullema
  • 20. Market Expectations: Dutch MNT Companies Company Product / Service Friesland Foods Application of micro fluidics in foods Holst Institute System in Package development IMS Micro Assembly Equipment Levitor ALD Equipment Lionix Development of technologies Mapper Lithographic Equipment Medspray Aerosol dispensing Medtronic Maastricht Medical equipment , pacemakers Microflown Acoustic pressure measurement Mikronit Lab-on-a-chip Miplazza Open innovation research facility 20Jan Eite Bullema
  • 21. Market Expectations: Dutch MNT Companies Company Product / Service Nanomi Functional Emulsions NT MDT Scientific Equipment for Nanotechnology NTS Ter Strake Equipment for Large Area Printing NXP Oscillators, BAW filters Oce Ink jet printing Phoenix Software Philips Electronics Various applications Pie Medical Ultrasonic imaging Sensata Pressure sensors Sentron Solid State pH sensor SolayTech ALD Equipment 21Jan Eite Bullema
  • 22. Market Expectations: Dutch MNT Companies Company Product / Service Solmates Pulsed Laser Deposition Tempress Production Equipment, ovens TNO Development of technology Wetsus Sustainable water technology XiO Photonics Optical switching Xensor Integration Hall sensors MinacNed is a Dutch interest group that brings companies together in this field. Regular meetings are organized for interested parties. A yearly conference Micro Nano Conference is organized, mostly in November of a year. http://www.minacned.nl/home.html 22Jan Eite Bullema
  • 23. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 23Jan Eite Bullema
  • 24. MEMS: Materials and Material Properties Silicon Silicon Oxide and Nitride Thin metal films Polymers Other materials and substrates Silicon Carbide, Gallium Arsenide, Shape Memory Alloys Important properties and physical effects Piezoresistivity, Piezoelectricity, Thermoelectricity, Hall Effect 24Jan Eite Bullema
  • 25. Silicon as a Mechanical Material Kurt Petersen 1982 25Jan Eite Bullema
  • 26. Mechanical Properties of Crystalline Silicon Silicon is hard and brittle. Yield strength of 7 G Pa (equivalent to 700 kg on 1 square millimetre) Young modulus is dependent on the crystal orientation. Average 160 GPa (for a (100) wafer E110 = 169 GPa E100 = 130 GPa) Mechanical properties are influenced by dopants (e.g. introduction of internal stress) 26Jan Eite Bullema
  • 28. Silicon is a Semiconductor A semiconductor is a material with an electrical conductivity that is intermediate between that of an insulator and a conductor. A semiconductor behaves as an insulator at very low temperature, and has an appreciable electrical conductivity at room temperature although much lower conductivity than a conductor. Bandgap Diamont (C) 5,9 eV Gallium Arsenide (GaAs) 1,42 eV Silicon (Si) 1,14 eV Germanium (Ge) 0,7 eV Tin (Sn) 0,01 eV Grafeen (C) 0 eV (halfmetal) A bandgap below 3 eV is associated with a semiconductor 28Jan Eite Bullema
  • 29. Impurity Doping Impurity doping. Introducing into a semiconductor material impurities of foreign atoms (dopants) in relative dilute concentrations Relative dilute is 10 13 - 10 20 foreign atoms / cm3 The impurities alter the electrical properties of the semiconductor. At room temperature the carrier concentration is nearly equal to the dopant concentration. If the dopant is n-type (Arsenic, Phosphorus) there is an excess of electrons. For p-type there is an excess of holes (dopant Boron) 29Jan Eite Bullema
  • 30. Electron Speeds in Various Semiconductors 30Jan Eite Bullema
  • 31. Resistivity of Doped Silicon 31Jan Eite Bullema
  • 32. Availability of Silicon Three forms of Silicon are relevant for MEMS - Crystalline - Poly Crystalline / poly silicon - Amorphous Crystalline silicon is available in circulair wafers 100 mm (4''), 150 mm (6''), 200 mm (8'') and 300 mm (12") 450 mm is expected in the near future 100 mm wafer has a thickness of 525 micron 150 mm wafer has a thickness of 650 micron 32Jan Eite Bullema
  • 33. Miller Indices Orientations in planes are often described in so-called Miller indices [100] x,y,z vector orientation <100> 6 directions +x,-x,+y,-y,+z,-y (111) a plane  on the [111] vector {111} describes all 8 equivalent (111) planes Planes and there orientations 33Jan Eite Bullema
  • 34. Anisotropic Properties of Silicon 34Jan Eite Bullema (a) face view (100); (b) edge view (110); (c) vertex view (111). Three crystallographic planes and their Miller indexes Four of the eight equivalent (111) planes in the {111} family.
  • 35. Anisotropic Properties of Silicon 35Jan Eite Bullema
  • 36. Silicon Wafers Material manufacturers cut thin circular wafers from silicon boules along specific crystal planes. The cut plane - the top surface of the wafer - is known as the orientation cut, and is encoded on the wafer itself in the form of a primary and a secondary flat located on the side of the wafer. Commercially available wafers are predominantly of {100} orientation, which is the preferred orientation cut for CMOS technology. In addition to the cut impurity doping (p or n) and electrical resistivity (in Ohm m) are specified by the supplier 36Jan Eite Bullema
  • 37. KOH Etch of Silicon 37Jan Eite Bullema The etch rate of silicon with KOH depends on: - the concentration of the KOH solution - the temperature - the Si crystal orientation
  • 38. Poly Silicon Usually deposited as layer or thin film (5 micron) on a surface. It is used as: - micromechanical structure (e.g in accelerometer of Analog Devices) - electrical interconnect - thermocouples - p-n junction Mature technology to create planar micro mechanical structures 38Jan Eite Bullema
  • 39. Poly Silicon an Amorphous Silicon The mechanical properties vary with deposition conditions, but in general they are the same as for single-crystal silicon Normally both suffer from intrinsic stress (hundreds of M Pa) which requires annealing at elevated temperatures (> 900 °C) Beams of poly silicon or amorphous silicon that have not been subjected to a careful stress annealing step can curl up under the effect of intrinsic stress 39Jan Eite Bullema
  • 40. Material Properties of Crystaline Silicon 40Jan Eite Bullema
  • 41. Interesting Properties of Silicon Silicon conducts heat circa 100 times better than glass. Silicon does not function as a Laser (as GaAs for instance does), but can interact with light and function as a detector. Silicon is transparent above wavelengths of 1,1 micron. Silicon reflects light below circa 400 nm (Bleu) at 60 % Above 500 degrees °C Silicon becomes soft, plastic deformation sets in. 41Jan Eite Bullema
  • 42. Interesting Properties of Silicon Silicon is resistant to most chemicals (e.g freon or brake fluids) Interaction with gasses, chemicals, biological fluids, and enzymes remains subject of studies In medicine and biology there are on-going studies to evaluate silicon for chronic medical implants. Preliminary medical evidence indicates that silicon is benign in the body and does not release toxic substances 42Jan Eite Bullema
  • 44. Selected Properties of Silicon 44Jan Eite Bullema
  • 45. Properties of Silicon Oxide SiO2 Softens above 700 degrees Celsius. Important that it is electrically insulating, unlike germanium oxide which oxide is also soluble in water. Gallium Arsenide which oxide can not be grown appreciably. Various forms of SiO2 and SiOx, silicate glass are used in micromachining due to their excellent electrical and thermal insulation properties. Also often used as sacrificial layer in surface micromachining processes, because they can be preferentially etched with hydrofluoric acid (HF) which is selective to Silicon 45Jan Eite Bullema
  • 46. Etching of SiO2 in KOH KOH etching of silicon dioxide is observable. The etch rates are considerably slower (1-2 orders of magnitude) than that of silicon but should be considered when deep etching is being done. 46Jan Eite Bullema
  • 47. Silicon On Insulator (SOI) SOI wafer, where the top single crystalline silicon layer (device layer) on an oxide film(buried oxide) is fabricated on a silicon wafer (handle wafer), is widely used in microsystems as well as in semiconductor devices. In microsystems, the most attractive feature is that the single crystalline silicon can be used as structural materials. In surface micromachined devices. Relatively thick SOI wafers, whose device layer thickness is more than a few microns, are widely used in accelerometers, vibrating gyroscopes, and micromirrors. 47Jan Eite Bullema
  • 48. Properties of Silicon Nitride Si3N4, SiyNx is also widely used as an insulation thin film, it has also excellent properties as a barrier against mobile ion diffusion. In particular sodium and potassium ions as found in biological environments Its Young modulus is higher than that of silicon and can be controlled by the specifics of the deposition process Silicon nitride is an effective masking material in many alkaline etching solution 48Jan Eite Bullema
  • 49. Etching of Silicon Nitride in KOH KOH etching of silicon nitride was not observed in the study. Therefore, the silicon nitride etch rate is under 1 nanometer per hour if it etches at all. If silicon nitride is being used as a mask for silicon etching, potential etching of the silicon nitride need not be taken into consideration. J. Electrochem. Soc. Vol 137, 11, Nov 1990, 3612-3632. 49Jan Eite Bullema
  • 50. Thin Metal Films Metal  .cm) Typical Areas of Application Ag 1.58 Electrochemistry Al 2.7 Electrical Inteconections Optical reflection visible & infrared Au 2.4 High Temp. Electrical Interconnect Optical reflection infrared Electrochemistry Cr 12.9 Intermdiate Adhesion Layer Cu 1.7 Low Resisitivity Interconnects ITO 300 - 3000 Transparent Conductive Layer W 5.5 High Temperature Interconnects 50Jan Eite Bullema
  • 51. Thin Metal Films Metal  .cm) Typical Areas of Application Pd 10.8 Electrochemistry Solder Wetting layer Permalloy - Magnetic Transducing Pt 10,6 Electrochemistry Electrodes for Bio-potential SiCr 2000 Thin Laser Trimmed Resistor SnO2 5000 Chemo-resistance Gas Sensors TaN 300 - 500 Negative TCR TiNi 80 Shape Memory Alloy TiW 75 - 200 Intermediate Adhesion Layer Near Zero TCR 51Jan Eite Bullema
  • 52. Thin Metal Films Metal  .cm) Typical Areas of Application Ir 5.1 Electrochemistry Micro Electrodes Bio-potential Ni 6.8 Magnetic Transducing NiCr 200 - 500 Laser-trimmed resistor 52Jan Eite Bullema
  • 53. Polymers (SU8) In silicon micromaching polymers are often deposited in thin layers from a few nanometers to hundreds of microns Special photoresists (e.g. SU-8) can be brought up to 1000 micron thick. Hardening under UV light produces rigid structures. Spin on organic polymers are general limited in their application due to shrinkage due to solvent evaporation 53Jan Eite Bullema
  • 54. SU8 SU-8 is a negative-tone photoresist chemically amplified resist system with excellent sensitivity and high aspect ratios. The primary applications are micro fabricated mechanical structures (MEMS) and other microsystems. Examples are sensors, microfluidic components, electronic coils, inkjet print head nozzles, MR and GMR heads, multichip modules, actuators, LCD spacers and moulds for plastic, stamps for hot embossing and electroplating 54Jan Eite Bullema
  • 55. PolyDiMethylSiloxane (PDMS) Polydimethylsiloxane is one of the most widely used polymers in MEMS, especially in microfluidic and bioMEMS. It belongs to a class of polymers called silicones, which are synthetic polymers containing a Si–O backbone. Silicones are different from most other polymers in that the backbone chain of atoms is silicon rather than carbon. Silicones are very compliant and have been used as the deformable membrane in valves, as well as being a common die-attach material in packaging. 55Jan Eite Bullema
  • 56. Glass, Quartz Glass and silicon fit together well. Close match of CTE and suitable for anodic bonding Quartz has as an extra advantage that it shows piezo electrical behaviour Machining can be done by: - HF etching, - ultrasonic machining or - powder blasting 56Jan Eite Bullema
  • 57. Silicon Carbide and Diamond Both materials offer extraordinary hardness and resistance to harsh environments. Micro machining of both materials is still in its infancy Both materials demonstrate piezoresistive properties Silicon carbide is sometimes used as a coating material for harsh environments Bandgap of SiC is 3,03 eV 57Jan Eite Bullema
  • 58. III-V Semiconductors Very well suitable for manufacture of lasers and other optical devices Use in RF devices and high speed electronics. GaN is becoming more important in LED applications and power electronic applications. • GaAs • InP • AlGaAs • GaN • InGaN 58Jan Eite Bullema
  • 59. Smart Memory Alloys Invented in 1951 AuCd alloy The material remembers its original form after being strained and deformed. Alloys: • TiNi • Cu Al Ni • FeNi • Fe Pt Practical limitation lies in the transition temperature. 59Jan Eite Bullema
  • 60. Jan Eite Bullema 60 Shape Memory Alloys A shape memory alloy (SMA) (also known as memory metal or smart wire) is a metal that remembers its geometry. After it is deformed, it regains its original geometry by itself during heating (one-way effect) or, at higher ambient temperatures, simply during unloading Jan Eite Bullema 60
  • 61. Jan Eite Bullema 61 Important Physical Effects Piezoresistivity Piezo electricity Thermoelectricity Hall-Effect Jan Eite Bullema 61
  • 62. Jan Eite Bullema 62 Strain Gauge A strain gauge is a device used to measure deformation (strain) of an object. The most common type of strain gage consists of a flexible backing which supports a metallic foil pattern etched onto the backing. As the object is deformed, the foil pattern is deformed, causing its electrical resistance to change. This resistance change, usually measured using a Wheatstone bridge circuit Jan Eite Bullema 62
  • 63. Jan Eite Bullema 63 Piezo electricity Certain classes of crystals exhibit the peculiar property of producing an electrical field when subjected to an external force They are attractive to MEMS because they can be used as well as sensors as well as actuators and they can be deposited as thin film on silicon Jan Eite Bullema 63
  • 64. Jan Eite Bullema 64 Piezo electric coefficients Jan Eite Bullema 64
  • 65. Jan Eite Bullema 65 Piezo electric effect Jan Eite Bullema 65
  • 66. Jan Eite Bullema 66 Thermo electricity The Seebeck effect is the conversion of heat differences directly into electricity. The Peltier effect is the reverse of the Seebeck effect; a creation of a heat difference from an electric voltage Thomson effect, describes the heating or cooling of a current-carrying conductor with a temperature gradient. Any current-carrying conductor, with a temperature difference between two points, will either absorb or emit heat, depending on the material. Seebeck is most used, in thermocouples to measure temperature differences Jan Eite Bullema 66
  • 67. Jan Eite Bullema 67 Seebeck coefficients relative to Pt Jan Eite Bullema 67
  • 68. Jan Eite Bullema 68 Hall Effect (www.sensedu.com) Jan Eite Bullema 68
  • 69. Jan Eite Bullema 69 Some Sensing methods Piezo resistive Capacitive Electromagnetic Thermoelectric Jan Eite Bullema 69
  • 70. Jan Eite Bullema 70 Capacitive sensing Capacitive sensing relies on an external physical parameter changing spacing or dielectric constant Advantage of capacitate measurement are (1) that it requires little energy (2) it is relative temperature insensitive (3) it gives the possibility to closed loop feedback Disadvantages are (1) Capacitive sensing requires large electronics Measurements can be done down to pF level Jan Eite Bullema 70
  • 71. Jan Eite Bullema 71 Piezo Electric actuation Piezo Electric actuation can provide relative large forces Thick Piezo electric films are used up to a few Newton's with a few hundred Volts applied Thin films ( < 5 micron) only a few milli Newton's Jan Eite Bullema 71
  • 72. Jan Eite Bullema 72 Actuators A complete paradigm change is necessary when thinking of actuating at a micro scale. A four stroke engine is not scalable Electrostatic Actuation Piezo Electric Actuation Thermal Actuation Magnetic Actuation Shape Memory alloys Jan Eite Bullema 72
  • 73. Jan Eite Bullema 73 Thermal Actuation Thermal actuation consumes more power than electrostatic or piezo electric actuation. But it can provide, despite its gross inefficiencies, actuation to hundreds of milli Newton's or higher - Traditional bimetal - Thermo pneumatic - Suspended beam heating Notice: First two methods are ambient temperature dependent Jan Eite Bullema 73
  • 74. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 74Jan Eite Bullema
  • 75. Jan Eite Bullema 75 MEMS Processes Basic Process Tools: Epitaxy, Oxidation, Sputter deposition, Evaporation, Chemical Vapor Deposition Spin-on methods, Lithography, Etching Advanced Process Tools: Anodic bonding, silicon fusion bonding, grinding polishing and Electrochemical polishing, Sol-gel deposition methods Bosch Process: DRIE Jan Eite Bullema 75
  • 76. Jan Eite Bullema 76 MEMS Processes Jan Eite Bullema 76
  • 77. Jan Eite Bullema 77 Epitaxy General method to grow a crystaline layer of silicon on a silicon wafer, with use of dopants specific properties can be given {AsH3, PH3 (n-type), B2H6 (p-type)} - layer thickness 1- 20 micron - same crystaline orientation as wafer - much used in CMOS (efficient p-n junctions) - Temperature (> 800 °C) with SiH4, SiH2Cl2, SiCl4 - grow speeds 0,2 - 1,5 micron per minute Jan Eite Bullema 77
  • 78. Jan Eite Bullema 78 Epitaxy: Silicon on Safire So called hetero epitaxy, were two different materials are grown. In this case Silicon on Safire (Al2O3) Process is called SOS Due to crystalline structure the layers of silicon on safire have to stay thin (due to increasing defects the electrical properties of silicon degrade) SOS is used when optical or electrical properties require this Jan Eite Bullema 78
  • 79. Jan Eite Bullema 79 Oxidation Silicon dioxide is obtained by oxidizing silicon with dry oxygen or steam at 850 - 1100 °C Very well known process. Oxidation introduces compression stress in the material because SiO2 needs more volume than Silicon The compression stress can be several hundreds MPa Stress in a layer can lead to warping and curling Jan Eite Bullema 79
  • 80. Jan Eite Bullema 80 Sputtering In sputtering a target material is bombarded with inert ions (e.g. Argon or Helium) Some material of the target is released and deposited on a wafer Three basic forms - DC glow discharge - Planar RF - Cylindrical Magnetron or S-gun Large range of materials: Al, Ti, Cr, Pt, Pa, Si, glass, Piezomaterial. Jan Eite Bullema 80
  • 81. Jan Eite Bullema 81 Sputtering Schematic illustration of a sputtering apparatus. In the sputtering process, positively charged argon ions strike the target biased negatively and remove target atoms. These sputtered atoms condense on the substrate to form a thin film. Sputtering parameters such as substrate temperature, sputter gas pressure, target-to- substrate distance, and target power play an important role in the structure and composition of deposited films. Jan Eite Bullema 81
  • 82. Jan Eite Bullema 82 Sputtering Depending on target size a good step covering can be obtained. The film has a fine granular structure Depending on the sputtering pressure the stress in the layer goes from tensile (low pressures 0,1 - 1.0 Pa) to compressive (1 - 10 Pa) Good pressure control is necessary for controlling stress Advantage of sputtering is the relative low temperature (150 C) Jan Eite Bullema 82
  • 83. Jan Eite Bullema 83 Evaporation Local heating of target material with subsequent condensation on a substrate. Nearly any material is suitable: Al, Si, Ti, Mo, glass, Al2O3, etc Inclusive refractory materials: W, Au, Cr, Pd, Pt as long as the vapor pressure is higher than the background pressure Important is that the carrier (mostly W) does not evaporate Stress in the layer can become very large (depending on the temperature) in W up to 500 MPa Jan Eite Bullema 83
  • 84. Jan Eite Bullema 84 Thermal Evaporation Jan Eite Bullema 84
  • 85. Jan Eite Bullema 85 Chemical Vapour Deposition Chemical Vapour Deposition is mostly a process at elevated temperatures (> 300 °C) Materials that can be deposited are: - silicon, - poly silicon - amorf silicon - SiO2 - Si3N4 - Cu and low r material Jan Eite Bullema 85
  • 86. 86Jan Eite Bullema Common CVD Deposition Chemistries
  • 87. Jan Eite Bullema 87 Chemical Vapour Deposition There two important forms of CVD: - Low pressure Chemical Vapour Deposition (LPCVD) - Plasma Enhanced Chemical Vapour Deposition (PECVD) LPCVD temperatures > 800 °C PECVD temperatures ~ 300 °C Many layer properties can be controlled with deposition parameters (pressure, temperature, gas flow, dopants, power and plasma excitation) Jan Eite Bullema 87
  • 88. Jan Eite Bullema 88 Example PE- CVD Equipment The Plasma Enhanced Chemical Vapor Deposition (PECVD) machine is used to deposit thin dielectric films. It combines up to four gases at pressures between 0.1 and 1 Torr and uses an RF source of up to 200 Watts to ionize the resultant gas mixture, causing film deposition on a heated substrate. Films deposited with the system include: SiO2, SiOxNy, and Si3N4. Jan Eite Bullema 88
  • 89. Jan Eite Bullema 89 Polysilicon with CVD Polysilicon deposition on a wafer can be done from tens of nm to several microns thickness on a silicon wafer Easy to apply by pyrolysis of Silane (SiH4) with LPCVD at 550 - 750 °C. PECVD is also possible. Depending on process conditions amorphous or crystalline silicon is obtained. Good step covering Stress can be reduced by annealing > 900 °C Jan Eite Bullema 89
  • 90. Jan Eite Bullema 90 Silicon dioxide with CVD Silane and oxygen in a CVD reactor result in on SiO2 layer Boron and or phosphorus can be build in to obtain specific properties. E.g. Low Temperature Oxide (LTO) which can be used to obtain an excellent step coverage of the SiO2 layer by heating to 1000 °C Silicon oxide also can be obtained by pyrolysis of [Si(OC2H5)4] TEOS (tetra ethoxy silane) in LPCVD at 650 - 700 °C Jan Eite Bullema 90
  • 91. Jan Eite Bullema 91 Silicon Nitride with CVD Silicon nitride is good for passivation and an excellent barrier for water and sodium ions. For MEMS it is an excellent mask for etching with KOH Stoichiometric Si3N4 is obtained by atmospheric CVD of SiH4 and NH3 or SiCl2H2 and NH3 at 700 - 900 °C H2 is absorbed in the layer which lead too large tensile stresses (e.g. 1000 MPa) Jan Eite Bullema 91
  • 92. Jan Eite Bullema 92 Spin on methods With spin on methods layers of dielectric insulators and organic materials can be applied A table spins with typical 500 - 5000 rpm Thicknesses are 0,5 - 20 micron For SU-8 epoxy it can be 1 up to 1000 micron Glasses also can be applied Jan Eite Bullema 92
  • 93. Jan Eite Bullema 93 Lithography Lithography has three essential steps: - application of photoresist with a photosensitive emulsion layer - optical exposure to print an image of the mask into the resist - immersion in an aqueous development solution to dissolve exposed resist and render visible the latent image Jan Eite Bullema 93
  • 94. Jan Eite Bullema 94 Lithography There are three main forms of lithography - Contact - Proximity - Projection Jan Eite Bullema 94
  • 95. Jan Eite Bullema 95 Lithography Resolution: - contact 1 - 2 micron - proximity 5 micron (Fresnel limitation) - projection (better than 1 micron) Depth of Focus is sometimes limiting for thicker structures Jan Eite Bullema 95
  • 96. 96Jan Eite Bullema Comparison Wet and Dry Etching
  • 97. Jan Eite Bullema 97 Example Lithography Equipment The Canon Parallel Light Mask Aligner is a machine used in the process of lithography. The shown machine allows for the use of 4-5 inch photomasks and can handle 2-5 inch wafers. Both the mask and wafer can be brought into sharp focus, facilitating the proper alignment of mask and wafer for maximum exposure accuracy. .The maximum print diameter is 5 inches, which is a relatively large exposure area. As such, the number of devices per wafer and throughput is increased. This Canon Aligner is also equipped with an auto feeder, allowing hands-off loading and unloading of the wafer Jan Eite Bullema 97
  • 98. Jan Eite Bullema 98 Double Sided Lithography Jan Eite Bullema 98
  • 99. Jan Eite Bullema 99 Thick resist With multiple spin on process a thick resist layer can be obtained. Due to height differences (topological height variations) some processes become very difficult. Jan Eite Bullema 99
  • 100. Jan Eite Bullema 100 Etching Etching processes in MEMS are derived from traditional etch processes for semiconductor processes. ‘Underpinning is in science, much remains an art’ The objective is to selectively remove material using imaged photoresist as a masking template. Jan Eite Bullema 100
  • 102. 102 Isotropic and Anisotropic Etching Jan Eite Bullema 102
  • 104. 104Jan Eite Bullema Anisotropic Etching: Suspended beam
  • 105. 105 Etchants of Thin Metal Films and Insulators Jan Eite Bullema 105
  • 106. Jan Eite Bullema 106 Deep Reactive Ion Etching (Bosch Process) Jan Eite Bullema 106
  • 107. Jan Eite Bullema 107 Deep Reactive Ion Etching (Bosch Process) Jan Eite Bullema 107
  • 108. Jan Eite Bullema 108 Deep Reactive Ion Etching (Bosch Process) Jan Eite Bullema 108
  • 109. 109 Isotropic wet Etching Common wet etchant is HNA also known as poly etch H = Hydrofluoric Acid (HF) N = Nitric Acid (HNO3) A = Acetic Acid (CH3COOH) Nitric acid oxidizes silicon which is removed by HF Etch depth and surface condition are mostly difficult to control (Etch rate up to 20 micron) Jan Eite Bullema 109
  • 110. Jan Eite Bullema 110 Anisotropic wet etching Anisotropic wet etchants include the hydroxides of alkali metals (KOH, NaOH, CsOH, etc), simple and quaternary ammonium hydroxides (NH4OH, (CH3)4NOH) Potassium hydroxide is the most common KOH etches the {111} planes 100 times faster than the {100} planes. This feature is routinely used to make V shaped grooves that are precisely delineated by the {111} crystallographic planes Jan Eite Bullema 110
  • 111. Jan Eite Bullema 111 Anodic bonding Bonding of silicon and sodium containing glass (Pyrex 7740 and 7070 or Schott 8330 and 8329) It is fundamental to manufacture of a wide variety of sensors, including pressure sensors, because it provides a rigid support in the form of a glass substrate rather than the fragile silicon bonding at 200 - 500 °C in vacuum, air or inert application of a voltage 500 - 1500 V across the two substrates Jan Eite Bullema 111
  • 112. Jan Eite Bullema 112 Anodic bonding Jan Eite Bullema 112
  • 113. Jan Eite Bullema 113 Silicon fusion bonding Silicon fusion bonding, also known as direct wafer bonding is a process capable of securely joining two silicon substrates The bonding mechanism is not well understood but it is widely believed that it occurs at a molecular level. Formation of OH groups on the surface and cleanliness are important. A temperature anneal at 800 - 1000 °C promotes and strengthen the bond reaction Jan Eite Bullema 113
  • 114. LIGA (LIthography, Galvanie, Abformung) Jan Eite Bullema 114
  • 115. Jan Eite Bullema 115 SU-8 Process Jan Eite Bullema 115
  • 116. Jan Eite Bullema 116 SU-8 Epoxy SU-8 Epoxy Structures Examples of SU-8 epoxy structures that are available as foundry processes. Structure heights from 1 micron to 1 millimeter are possible and side-wall angle can also be controlled for various geometries. Jan Eite Bullema 116
  • 117. Jan Eite Bullema 117 Process Flow Jan Eite Bullema 117
  • 118. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 118Jan Eite Bullema
  • 119. Jan Eite Bullema 119 MEMS Products Pressure Sensor Accelerometer Mass Flow Sensors Digital Micro mirror Device Angular Rate Sensors Fluid Nozzles, inkjet print nozzles, micro filtration Micro machined valves Jan Eite Bullema 119
  • 120. Jan Eite Bullema 120 Relative Merits different sensing principles Jan Eite Bullema 120
  • 121. Jan Eite Bullema 121 Pressure sensor Jan Eite Bullema 121
  • 122. Jan Eite Bullema 122 Fabrication steps for a piezoresistive gauge Pressure sensor Jan Eite Bullema 122
  • 123. Jan Eite Bullema 123 Pressure sensor Jan Eite Bullema 123
  • 124. Jan Eite Bullema 124 Pressure sensor Fabrication process of a SOI high-temperature pressure sensor. Jan Eite Bullema 124
  • 126. Jan Eite Bullema 126 Pressure sensor The machined silicon-structure is protected in an elektronics package Jan Eite Bullema 126
  • 127. Jan Eite Bullema 127 Nano Probe Beams of the Silicon part are 20 – 30 m thick, the function of the nano probe requires thin beams For assembly thin beams are challenging Jan Eite Bullema 127
  • 128. Jan Eite Bullema 128 Flow Sensor Gas flow cools the upstream heater and heats the downstream heater. Temperature-sensitive resistors are used to measure the temperature of each heater and consequently infer the flow rate. The etched pit underneath the heater provides exceptional thermal isolation to the silicon support frame. Jan Eite Bullema 128
  • 129. Jan Eite Bullema 129 Accelerometer Acceleration (1) Front and side airbag crash sensing (2) Electrically controlled car suspension. (3) Safety belt pretensioning . (3) Vehicle and traction control systems. (4) Inertial measurement, (5) object positioning, and navigation (6) Human activity for pacemaker control Vibration (1) Engine management (2) Condition-based maintenance of engines and machinery (3) Security device (4) Shock and impact monitoring (5) Monitoring of seismic activity Angles of inclination (1) Inclinometers and tilt sensing (2) Vehicle stability and roll (3) Computer peripherals (e.g., joystick,head mounted displays … ) (4) Handwriting recognition (e.g., SmartQuill from British Telecom) (5) Bridges, ramps, and construction Jan Eite Bullema 129
  • 130. Jan Eite Bullema 130 Acclerometer: Principle Jan Eite Bullema 130
  • 131. Jan Eite Bullema 131 Differences in G measurements Airbag 50 G Bandwidth 1 k Hz Motor sensor: 1 G resolution 100 micro G Bandwidth > 10 kHz Hart sensor: 2 G Bandwidth 50 Hz ultra low power consumption Military sensor: 1000 G Drop test: 10 000 G Jan Eite Bullema 131
  • 132. Jan Eite Bullema 132 Accelerometer Illustration of a piezoresistive accelerometer from Endevco Corporation fabricated using anisotropic etching in {110} wafers. The middle core contains the inertial mass suspended from a hinge. Two piezoresistive sense elements measure the deflection of the mass. The axis of sensitivity is in the plane of the middle core. Jan Eite Bullema 132
  • 133. Jan Eite Bullema 133 Bulk micro machined PZR sensor Proof mass typical 100 micro grams PZR (Boron doped Silicon) 0,6 micro thick 3,4 micron broad Signal in Wheatstone bridge typical 1 G / 25 mV over 10 V Measurement until 6000 G Shock proof 10000 G Bandwidth 28 k Hz Jan Eite Bullema 133
  • 134. Jan Eite Bullema 134 Accelerometer Capacitive bulk-micromachined accelerometer. The inertial mass in the middle wafer forms the movable electrode of a variable differential capacitive circuit. Adapted from the accelerometer product catalog Jan Eite Bullema 134
  • 135. Jan Eite Bullema 135 Accelerometer Process steps to fabricate the middle wafer containing the hinge and the inertial mass of a capacitive bulk-micromachined accelerometer Jan Eite Bullema 135
  • 136. Jan Eite Bullema 136 Bulk Micro Machined Capacitive Sensor Proof mass typical 100 micro grams Capicitance translated to + - 2,5 V Measurement 1.5 to 50 G Shock proof 20000 G Bandwidth 400 Hz Jan Eite Bullema 136
  • 137. Jan Eite Bullema 137 Accelerometer Basic structure of the ADXL family of surface- micromachined accelerometers. A comb-like structure suspended from springs forms the inertial mass. Displacements of the mass are measured capacitively with respect to two sets of stationary finger-like electrodes. Jan Eite Bullema 137
  • 138. Jan Eite Bullema 138 Surface Micro Machined Capacitive Sensor Proof mass typical 0.3 to 1 micro grams Total capacitance 100 f F (f = femto = 10-15) Measurement 100 aF (a = atto = 10-18) 100 aF equals circa 625 electrons no parasitic currents are allowed all signal processing on the sensor Measurement typical airbag 1 - 50 G Price current below 3 USD per product (Bosch and Analog Devices) Jan Eite Bullema 138
  • 139. Jan Eite Bullema 139 Accelerometer Photograph of a deep-reactive-ion-etched (DRIE) accelerometer using 60-mm-thick comb structures. Jan Eite Bullema 139
  • 140. Jan Eite Bullema 140 DRIE Capacitive Sensor Proof mass typical 43 micro grams Total capicitance 3 pF (p = pico = 10-12) Thermal Noise: 10 G /  Hz Compared to surface micro machined sensor Thermal Noise: 500 G /  Hz Jan Eite Bullema 140
  • 141. Jan Eite Bullema 141 Accelerometers Commercial accelerometers only cost a few Euros Jan Eite Bullema 141
  • 142. Jan Eite Bullema 142 Angular-rate sensor A conventional mechanical gyroscope and the three rotational degrees of freedom it can measure. Jan Eite Bullema 142
  • 143. Jan Eite Bullema 143 Angular-rate sensor The Coriolis acceleration on an object moving with a velocity vector v on the surface of Earth from either pole towards the equator. The Coriolis acceleration deflects the object in a counterclockwise manner in the northern hemisphere and a clockwise direction in the southern hemisphere. The vector  represents the rotation of the planet. Jan Eite Bullema 143
  • 144. Jan Eite Bullema 144 Angular-rate sensor Tuning fork structure for angular-rate sensing. The Coriolis effect transfers energy from a primary, flexural mode to a secondary, torsional mode. Jan Eite Bullema 144
  • 145. Jan Eite Bullema 145 Angular-rate sensor The corresponding standing wave pattern Jan Eite Bullema 145
  • 146. Jan Eite Bullema 146 Angular-rate sensor Angular-rate sensor. The basic structure consists of a ring shell suspended from an anchor by support flexures. A total of 32 electrodes (only a few are shown) distributed around the entire perimeter of the ring excite a primary mode of resonance using electrostatic actuation. A second set of distributed electrodes capacitively sense the vibration modes. The angular shift of the standing wave pattern is a measure of the angular velocity. Jan Eite Bullema 146
  • 147. Jan Eite Bullema 147 Angular-rate sensor VSG angular-rate sensor from British Aerospace Systems and Equipment, and corresponding fabrication process. The device uses a vibratory ring shell design, similar to the Delco sensor. Eight current loops in a magnetic field, B, provide the excitation and sense functions. For simplicity, only one of the current loops is shown. Jan Eite Bullema 147
  • 148. Jan Eite Bullema 148 Angular-rate sensor Angular-rate sensor from Daimler Benz. The structure is a strict implementation of a tuning fork in silicon. A piezoelectric actuator excites the fork into resonance. The Coriolis force results in torsional shear stress in the stem which is measured by a piezoresistive sense element. Jan Eite Bullema 148
  • 149. Jan Eite Bullema 149 Angular-rate sensor The main fabrication steps for the Daimler Benz micromachined angular-rate sensor. Jan Eite Bullema 149
  • 150. Jan Eite Bullema 153 Carbon monoxide sensor Carbon monoxide sensor, its equivalent circuit model, and the final packaged part. The surface resistance of tin-oxide changes in response to carbon monoxide. A polysilicon heater maintains the sensor at a temperature between 100 and 450º C in order to reduce the adverse effects of humidity. Jan Eite Bullema 153
  • 151. Jan Eite Bullema 154 DMD™ Single DMD™ pixel in its resting and actuated states. The basic structure consists of a bottom aluminum layer containing electrodes, a middle aluminum layer containing a yoke suspended by two torsional hinges, and a top reflective aluminum mirror. An applied electrostatic voltage on a bias-electrode deflects the yoke and the mirror towards that electrode. A pixel is 17 m on a side. Jan Eite Bullema 154
  • 152. Jan Eite Bullema 155 DMD™ Optical beam-steering using the switching of micromirrors. Off-axis illumination reflects into the pupil of the projection lens only when the micromirror is tilted in its +10º-state, giving the pixel a bright appearance. In the other two states, the pixel appears dark Jan Eite Bullema 155
  • 153. Jan Eite Bullema 156 DMD™ Jan Eite Bullema 156
  • 154. Jan Eite Bullema 157 DMD™ Jan Eite Bullema 157
  • 155. Jan Eite Bullema 158 DMD™ Jan Eite Bullema 158
  • 156. Jan Eite Bullema 159 Grating Light Valve Operating principle of a single pixel in the grating light valve. Electrostatic pull- down of alternate ribbons changes the optical properties of the surface from reflective to diffractive. Jan Eite Bullema 159
  • 157. Jan Eite Bullema 160 Passive structures Nozzles are the most simple passive structure Patents for IBM In the 1970s for silicon nozzles for ink jet application Patents for Ford in the 1980s for motor fuel injection applications Nowadays these patents are expired. Many new research in the field of medical inhalers, atomizers, fluid spray systems Jan Eite Bullema 160
  • 158. Jan Eite Bullema 161 Passive structure Jan Eite Bullema 161
  • 159. Jan Eite Bullema 162 Passive structures Jan Eite Bullema 162
  • 160. Jan Eite Bullema 163 Inkjet Cross-sectional illustration of a thermal inkjet head and the ink firing sequence. Jan Eite Bullema 163
  • 162. Jan Eite Bullema 167 Various actuation methods Jan Eite Bullema 167
  • 163. Jan Eite Bullema 168 Micro Valves Jan Eite Bullema 168
  • 164. Jan Eite Bullema 169 Micro Valves Jan Eite Bullema 169
  • 165. Development of Microfluidic Interconnection Jan Eite Bullema Areas of Expertise 172
  • 166. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 173Jan Eite Bullema
  • 169. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 176Jan Eite Bullema
  • 170. Medical Applications of Micro and Nano Technology Jan Eite Bullema ‘It would be interesting in surgery if you could swallow the surgeon’ Richard P. Feynman 177
  • 171. Jan Eite Bullema 178 Pacemaker The pacemaker is one of the oldest examples of a MST product Jan Eite Bullema 178
  • 172. Jan Eite Bullema 179 Pacemaker Historic Developments (1950) Jan Eite Bullema 179
  • 173. Jan Eite Bullema 180 Pacemaker Historic Developments (2000s) Jan Eite Bullema 180
  • 174. Jan Eite Bullema 181 Pacemaker ( Integration of Functions) Integration of Functions In the pacemaker by: - MEMS Accelerometer - Digital control - Remote diagnostics - use of MEMS switches Jan Eite Bullema 181
  • 175. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Pacemaker Decreasing Dimensions MEDTRONIC, is using micro electronics and chip manufacturing to shrink pacemakers – implanted devices that regulate the hearts rhythm. Whereas current pacemakers are the size of a silver dollar. Medtronics new device would be smaller than a tic-tac. At that size the pacemaker could be inserted through a catheter rather than invasive surgery http://www.technologyreview.com/biomedicine/32436
  • 176. Jan Eite Bullema 183 Implantable wireless pressure sensor CardioMEMs’ device measures blood pressure in people who have an abdominal aortic aneurysm. Doctors can treat the bulging artery with a stent graft, stents can fail, aneurysm patients require lifetime monitoring Jan Eite Bullema 183
  • 177. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Implantable wireless pressure sensor 184
  • 178. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technolo Stents 185
  • 179. Jan Eite Bullema 186 Hearing Aid Trend is that products become smaller and smarter This is enabled by developments In micro electronics and in micro systems technology Jan Eite Bullema 186
  • 180. Jan Eite Bullema 187 Type Typical cost Euro per unit Behind the ear 200 - 300 In the ear 500 - 700 In the canal 700 - 1000 Completely in the canal 1400 - 2000 Cochlear Implants 35000 - 50000 Hearing Aids & Cochlear implants Jan Eite Bullema 187
  • 181. Jan Eite Bullema 188 Hearing Aids Source: Phonak Jan Eite Bullema 188
  • 182. Jan Eite Bullema 189 Cochlear Implants 1985 1991 1997 1999 2000 2004 Jan Eite Bullema 189
  • 183. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Flexible Solar Retinal Implants Age related Macular Degeneration (AMD) Affects about 1,5 Million people per year in the US and is the most prevalent cause for blindness in the US
  • 184. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Flexible Solar Retinal Implants
  • 185. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Flexible Solar Retinal Implants
  • 186. Retinal Implant Jan Eite Bulllema 193 Jan Eite Bullema 193
  • 187. jan_eite.bullema@tno.nl Medical Applications of Micro and Nano Technology Eye pressure measurement in glaucoma patients In the eye pressure sensor - a pressure sensor - a low-power microprocessor - a solar cell - a wireless radio - memory - and a thin film battery. http://techknowbits.com
  • 188. Jan Eite Bullema 195 Endoscope Source: PENTAX FG-32UA Jan Eite Bullema 195
  • 189. Jan Eite Bullema 196 Smart pill This smart-pill (M2A capsule) contains a number of the functions that a microsystem can have: - The pill can observe with a camera - The pill has a processor to process signals to information -The pill has coil to transmit information - The pill has a battery for energy supply purposes Jan Eite Bullema 196
  • 190. Jan Eite Bullema 197 Properties of the smart pill The capsule is 11mm x 26mm (<4 grams) Field of view is 140 degrees. Detection of objects at a minimum size less than 0.1 mm In a normal (8 hr) procedure the generates approximately 57,000 images, at a rate of two frames / second. Jan Eite Bullema 197
  • 191. Jan Eite Bullema 198 Capsule Endoscopy Image Eosinophilic Enteritis visualizing folds of the cecum Cecum Nematodes Pinworm in healthy volunteer Note thickened... Kaposi’s Sarcoma cutaneous Kaposi’s Normal ColonHemorrhagic 60 year old woman Normal vessels Jan Eite Bullema 198
  • 192. Jan Eite Bullema 199 Billicheck improves comfort Not a heel puncture but an optical measurement The analysis is done with a plastic grating The grating is made with LIGA technology Jan Eite Bullema 199
  • 193. Jan Eite Bullema 200 Optical Diagnosis with MST components Source: Micro Parts Color Check of Teeth Bili Check for Jaundice Jan Eite Bullema 200
  • 194. Jan Eite Bullema 201 Drug Delivery Pill: iPill by Philips Philips has developed a drug delivery pill (2.6 x 1.1 Ø cm) 30% is drug container It measures pH and temperature and can deliver drugs on site IMAPS iPill for controlled drug delivery – Frits Dijksman, November 20-th 3-rd, 2008
  • 195. Jan Eite Bullema Drug Delivery Pill: iPill by Philips Length small intestines 4-6 m Drift velocity (due to peristalsis) in small intestines 1 m/h Residence time in small intestines 4-5 hrs Length large intestines 1-1.5 m Throughput time1-5 days 202
  • 196. Jan Eite Bullema Drug Delivery Pill: iPill by Philips 203
  • 197. Jan Eite Bullema Drug Delivery Pill: iPill by Philips • Crohn’s Disease and Ulcerative Colitis • Chronic autoimmune disease of • unknown etiology • Prevalence: ~1.4M in U.S., similar in Europe • High patient burden and cost to society • Significant unmet needs in diagnosis, treatments, and disease management 204
  • 198. Jan Eite Bullema Drug Delivery Pill: iPill by Philips • Dimensions length 26 mm, diameter 11 mm • Weight 3.2 gr (specific mass 1450 kg/m3) • Medication content 300 micro liter • Minimum dispensed volume 1 micro liter • Once per 20 seconds the status on temperature, pH, medication content, battery will be transmitted to the outside of the body • Reach RF link 0.3 m in the body 205
  • 199. Jan Eite Bullema Drug Delivery Pill Diagnostic Therapeutic Non-invasive Non Invasive Miniaturized Miniaturized Patient Comfort Intelligent Device Ease of Use Individual Therapy High Data Content Disease Management Faster Health Monitoring Cheaper Compliance Monitoring 206
  • 200. Jan Eite Bullema207 Permanent medication dosing The artificial pancreas gives the diabetic patient a continuous and correct dosing of insulin
  • 201. Jan Eite Bullema208 Insulin Dispenser Debiotech’s Insulin Nanopump Each pump actuation injects only 200 nanoliters of drug,and reproducibility is better than 2%, bringing it very close to physiological delivery of insulin.
  • 202. Jan Eite Bullema209 Aerosol dispenser By the micro holes an aerosol can be dispensed with droplets of a very well defined droplet diameter (droplets of circa 1 micron diameter)
  • 203. Jan Eite Bullema Aerosol dispenser 210
  • 204. Jan Eite Bullema 211 Catheters for key-hole surgery A surgical doctor inspects a pressure sensor before he Starts measuring the pressure in the heart of the patient Jan Eite Bullema 211
  • 205. Jan Eite Bullema 212 Catheters for brain measurements Length: 340 mm Diameter: 0,6 mm Electrodes: 31 + 1 Array length: ca. 6 mm Jan Eite Bullema 212
  • 206. Jan Eite Bullema 213 Neuroprobes for brain probing 2mm shank length: 112 electrodes 8 mm shank length: 512 electrodes Jan Eite Bullema 213
  • 207. Jan Eite Bullema 214 Full 3D array for brain probing Jan Eite Bullema 214
  • 208. Jan Eite Bullema 215 Microfluidics: Market World Market Microfluidics (MST News Feb 2008) 2004 2009 (prognosis) Volume 630 M USD 1500 M USD Microfluidic Chips 65% 67% Pressure Sensors 23% 13% Drug Delivery 1% 13% IR Sensors 5% 3% Micro Spectrometers 3% 2% Other 2% 3% Jan Eite Bullema 215
  • 209. Jan Eite Bullema 216 Lab-on-a-chip (micro array) By capillary action the sample is pulled to the reactive spots Small sample volume + large number of analysis simultaneously Jan Eite Bullema 216
  • 210. Jan Eite Bullema 217 Microfluidics: Overview One important manner in which microfluidics differs from micro electronics. Is that the fundamental physics changes more rapidly as the size scale is decreased Micro fluidics quickly reach length scales were fundamental fluid physics change dramatically. E.g. Reynolds (Re) = inertial / viscous = . U0 .L0 /  Péclet (Pe) = convection / diffusion = U0 . L0 / D Capillary (Ca) = viscous / interfacial =  . U0 /  Jan Eite Bullema 217
  • 211. Jan Eite Bullema 218 Micro fluidics: Reynolds (viscous / interfacial) Reynolds (Re) = inertial / viscous = . U0 .L0 /  Flow in micro channels has typically Re 10 -6 to 10 { water (1 mPa.s, diameter (L0) 1 – 100 mm, flow (U0) 1m/s to 1cm/s } Flow in micro channels is always laminair as viscous forces >> inertial forces Spermatozoa ~ 1×10 −2 Blood flow in brain ~ 1×102 Blood flow in aorta ~ 1×103 Onset of turbulent flow ~ 2.3×103 Person swimming ~ 4×106 Aircraft ~ 1×107 Blue whale ~ 3×108 A large ship (RMS Queen Elizabeth 2) ~ 5×109 Jan Eite Bullema 218
  • 212. Jan Eite Bullema 219 Microchannels in Plastics Micro channels are used more and more in ‘Lab on a Chip’ products The example is a capillary with a width of 100 micron Jan Eite Bullema 219
  • 213. Jan Eite Bullema 220 Lab-on-a-Disk The Gyros device uses a passive valve principle. Some parts of the micro-channels have hydrophobic properties. These will act as a closed valve, fluid can not pass due to the hydrophobic surface. As the device is rotated, centrifugal forces will overcome the hydrophobic forces and pass the hydrophobic valve region. Gyros: Lab-on-a-Disk Jan Eite Bullema 220
  • 214. Jan Eite Bullema 221 Legionella detection Jan Eite Bullema 221
  • 215. Jan Eite Bullema 222 Smart Diagnostics for Healthcare Sample Biopsy Filtering / Concentrating Lysis / Extract DNA Seperating DNA / Rest PCR Washing / Filtering DNA detection Sample preparation and analysis on a 1’ x 3’ (25 x 75 mm) lab-on-a-chip Washing 1 2 3 4 4 65 7 Jan Eite Bullema 222
  • 216. Jan Eite Bullema 223 Genome Size FERN 160,000,000,000 LUNGFISH 139,000,000,000 SALAMANDER 81,300,000,000 NEWT 20,600,000,000 ONION 18,000,000,000 GORILLA 3,523,200,000 MOUSE 3,454,200,000 HUMAN 3,400,000,000 31,000 Drosophila 137,000,000 13,500 C. Elegans 96,000,000 19,000 Yeast 12,000,000 6,315 E. Coli 5,000,000 5,361 smallest Genome ?????? genes Jan Eite Bullema 223
  • 217. Jan Eite Bullema 224 Cells Humans 60 trillion (1012) cells 320 cell types Jan Eite Bullema 224
  • 218. Jan Eite Bullema 225 Jan Eite Bullema 225 The original Watson and Crick’s paper
  • 219. Jan Eite Bullema 226 The central dogma of molecular biology DNA RNA proteintranscription translation Jan Eite Bullema 226
  • 220. Jan Eite Bullema 227 PCR = Polymerase Chain Reaction Jan Eite Bullema 227
  • 221. Jan Eite Bullema 228 Silicon PCR chamber Jan Eite Bullema 228
  • 222. Jan Eite Bullema 229 Capillary Electrophoresis Jan Eite Bullema 229
  • 223. 230Jan Eite Bullema Capillary Electrophoresis
  • 224. 231Jan Eite Bullema Capillary Electrophoresis
  • 225. Jan Eite Bullema 232 Capillary Electrophoresis Jan Eite Bullema 232
  • 226. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 233Jan Eite Bullema
  • 227. Jan Eite Bullema 234 Packaging of MEMS Packaging of MEMS converts a machined structure into a useful assembly that can safely and reliable interact with its environment Definition of MEMS packaging is broad because each application is unique in its packaging requirements Function = Protect the micro machined structure to a broadening range of environments. It must also provide interconnections toelectrical signals, electrical interconnect, access to environment and interaction with environment Jan Eite Bullema 234
  • 228. Jan Eite Bullema 235 Packaging Hierarchy (level of packaging) Jan Eite Bullema 235
  • 229. Jan Eite Bullema 236 Package Functions - Power distribution - Signal distribution - Heat dissipation - Protection - Manufacturability / Processing of Components Jan Eite Bullema 236
  • 230. Jan Eite Bullema 237 Typical MEMS packaging process flow Jan Eite Bullema 237
  • 231. Jan Eite Bullema 238 Saw and Dice wafer In a FAB thousands of micro structures are made simultaneously. Dicing separates the structures into individual components Most common is a diamond saw with 75 - 250 micron thick blades, The wafer is held by a blue colored sticky tape and the wafer is cooled continuously Potential damaging of the structure during the process Sometimes the last sacrificial etching is done after dicing Jan Eite Bullema 238
  • 232. Jan Eite Bullema 239 Process Flow Wire Bonding Jan Eite Bullema 239
  • 233. Jan Eite Bullema 240 Characteristics Flip Chip Bonding Flip Chip implies bonding the die face down. Electrical contacts are made by means of plated bumps between bond pads on the die and metal pads on the package substrate. The attachment is intimate with small spaces (50 - 200 micron) between the die and the package. The pads can be all over the surface of the die (area arrays) resulting in an increase in density of (I/Os) Inductance of a solder bump is less than 0.05 nH compared to 1 nH for a 125 micron long and 25 micro thick wire bond Jan Eite Bullema 240
  • 234. Jan Eite Bullema 242 Thermal Condsiderations More complex chips make more demands on efficient heat removal from the chips. Silicon chips limited to approximately 100ºC for normal operation which limits power densities on chip to a maximum of 10watts/cm2 in current IC packages. Imposes a limit average on power dissipation per individual circuit on chip of approximately 1µW/circuit for a 10 million transistor chip of area 1cm × 1 cm. Jan Eite Bullema 242
  • 235. Jan Eite Bullema 243 Thermomechanical Considerations Important to reduce power dissipation/circuit and improve package thermal design in order to produce larger, more complex ICs in the future. Differential thermal expansion of package parts gives rise to mechanical stresses and reliability risks. E.g. Coffin Manson behaviour # cycles before failure = Function ( thickness / T *  CTE) Jan Eite Bullema 243
  • 236. Jan Eite Bullema 244 Package Sealing and Encapsulation Intended to protect the chip and package metallisation from corroding environments and from mechanical damage due to handling. Moisture is one of the major sources of corrosion. Plastic materials, such as silicones and epoxies, developed with low water diffusion properties are used extensively for IC encapsulation. For high reliability devices hermetic sealing used based on welding or brazing of ceramic/metal packages. More expensive and time-consuming than plastic encapsulation Jan Eite Bullema 244
  • 237. Jan Eite Bullema 245 Protective coating and media isolation Coatings are often used in flow sensors and pressure sensors. - in cars salt water sprays, acid rain polutants can attack the sensor - home applyances oftengive alkaline environments An often used coating is parylene ( p-xylylene) which can be deposited at room temperature and gives a conformal coating resistant to: exhaust gasses, fuel, salt spray, water, alcohol, organic solvents. Strong acids and bases dissolve parylene Jan Eite Bullema 245
  • 238. 246Jan Eite Bullema Thermal Shock Thermal Humidity Corrosive Dust Vibration Power Cycling Voltage Margining Frequency Margining Relative Causes for Failure in Electronics
  • 239. Jan Eite Bullema 247 Characteristics of Ceramic Packaging Ceramics are hard and brittle materials made by shaping a nonmetalic mineral, then firing at high temperatures for densification. Most ceramics are electrical insulators and good thermal conductors Jan Eite Bullema 247
  • 240. Jan Eite Bullema 248 Process Flow Ceramic Package Jan Eite Bullema 248
  • 241. Jan Eite Bullema 249 Ceramic Packaging of DMD The DMD package is a ceramic package. A DMD sells for several hundred dollars. An accelerometer packaged in ceramic would cost 35 USD, a plastic packaged accelerometer only 2-4USD Jan Eite Bullema 249
  • 242. Jan Eite Bullema 250 Capping Jan Eite Bullema 250
  • 243. 251Jan Eite Bullema Thin Film Capping
  • 244. Jan Eite Bullema 252 Metal Package Metal packages are attractive for MEMS because they can be prototyped in small series and are hermetic. Disadvantage is the high costs relative to plastic Jan Eite Bullema 252
  • 248. Jan Eite Bullema 256 Molded plastic packaging Post molded: plastic is molded after the die is attached to a lead frame (process subject die and interconnect to harsh molding conditions) A major disadvantage of plastic packages is hat they are not hermetic Yet in traditional electronics plastic packages are prefered: low cost few pennies per pin high reliability: one failure per billion hours operating time Jan Eite Bullema 256
  • 249. Jan Eite Bulema 257 Plastic Cap for MEMS Feasibility of polymers for wafer scale packaging of RF MEMS P.J. Bolt, J.E. Bullema, R. Korbee, 4M, Cardiff 2008 Jan Eite Bullema 257
  • 250. Jan Eite Bullema 258 3D - Packaging 3D Technology according to Suss Jan Eite Bullema 258
  • 251. Jan Eite Bullema 259 3D - Packaging (e.g. MEMS Scale Package) J.E. Bullema, M.H.M. Meuwissen, E.P. Veninga, " Design Study for Stacked MEMS", Proceedings Eurosime 2003, Key note Paper, 30 March - 2 April 2003, p279..283, Jan Eite Bullema 259
  • 252. Jan Eite Bullema 260 3D - Packaging Typical System in Package in 2010 [Wolf,2007] Jan Eite Bullema 260
  • 253. 261Jan Eite Bullema Tire Pressure Sensor (FHG – IZM)
  • 254. 262Jan Eite Bullema TX on micro processor (FHG – IZM)
  • 255. 263Jan Eite Bullema RF sensor with TSV (Omron)
  • 256. 264Jan Eite Bullema RF sensor with TSV (Omron)
  • 257. 265Jan Eite Bullema Future MEMS Packaging with TSV
  • 258. Build Up of the Micro- and Nanotechnology course Introduction History, markets, expectations Materials for micro and nano Processes and technologies Micro and nano products Converging technologies: MNBT Medical applications Packaging Wrap-up / multiple choice test 266Jan Eite Bullema
  • 259. Jan Eite Bullema 267 Wrap - Up Some Collective Multiple Choise A typical proof mass of an accelerometer is in the range of: A 10 micro gram to 100 micro gram B 100 micro gram to 1 milligram C 1 micro gram to 100 micro gram D 0,1 micro gram to 100 micro gram Jan Eite Bullema 267