This chapter introduces simple (bivariate, linear) regression analysis. It covers computing the regression line equation from sample data and interpreting the slope and intercept. It also discusses residual analysis to test regression assumptions and examine model fit, and computing measures like the standard error of the estimate and coefficient of determination to evaluate the model. The chapter teaches how to use the regression model to estimate y values and test hypotheses about the slope and model. The overall goal is for students to understand and apply the key concepts of simple regression.