1 The Outcomes of Neural Stem Cell Transplantation and Localized Drug Therapy on Patients Suffering from Traumatic Brain Injury John Doe Panther ID: 1212121 Assignment #3 Florida International University 2 Method Traumatic Brain Injury (TBI) is a resonating issue here in the U.S. and it comes as no surprise that it has increased in awareness as one of the nation’s most prevalent injury related deaths within the last 15 years (American Speech-Language-Hearing Association [ASHA], 2009). It is an illness of great importance due to its association of injuries related to military combat operations, both the Department of Defense (DoD) and Veteran Affairs (VA) are recognized leaders in TBI care and are in constant joint health practices with research based universities such as The University of Miami Miller School of Medicine and The University of Michigan Health System [UMHS] (Dennis, 2013). My methods paper will incorporate a holistic overview of the overall effectiveness of Neural Stem Cell (NSC) engraftment on TBI patients based on publications reported within scholarly journals. The overall efficacy of treatment will be compared to many control groups that serve as a basis to see if NSC outcomes lessen or diminish possible injuries, as a disclaimer, findings within TBI based research do not support nor condone that there is a cure to secondary injuries such as comas, neuronal cell death, loss of motor or cognitive function, paralysis, or even death due to TBI. Simply put, this research paper will look at collaborative efforts that a controlled laboratory setting has made in regards to ameliorating TBI conditions in either acute or severe injuries and review the success of treatment in the hopes that it can serve patients and their respective loved ones in finding more adequate treatment platforms that can efficiently save lives in the long run. Research Method & Design Appropriateness According to Martyn Shuttleworth (2008), the top three most widely used research methods are Experimental Research Methods, Opinion Based Research Methods, and Observational Research Methods. There are a myriad of factors to take into account and evaluate 3 when choosing the correct research method. Every experimental design must make compromises and generalizations, so each individual researcher must minimize these, but, also do it while being realistic (Shuttleworth, 2008). Experimental Research Methods is a more straightforward experiment that involves the standard practice of manipulating quantitative data and independent variables to generate statistically analyzable data. The results generated can be quantified using a testable hypothesis, with statistical information giving a clear and unambiguous picture (Shuttleworth, 2008). Opinion Based Research Methods generally involve designing an experiment and collecting numerical data that that can be repr ...